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1.
Clin Oral Investig ; 28(8): 417, 2024 Jul 08.
Artigo em Inglês | MEDLINE | ID: mdl-38972945

RESUMO

OBJECTIVES: The treatment of fractures prioritizes the restoration of functionality through the realignment of fractured segments. Conventional methods, such as titanium plates, have been employed for this purpose; however, certain limitations have been observed, leading to the development of patient-specific plates. Furthermore, recent advancements in digital technology in dentistry enable the creation of virtual models and simulations of surgical procedures. The aim was to assess the clinical effectiveness of patient-specific plates utilizing digital technology in treating mandibular fractures compared to conventional titanium plates. MATERIALS AND METHODS: Twenty patients diagnosed with mandibular fractures were included and randomly assigned to either the study or control groups. The surgical procedure comprised reduction and internal fixation utilizing patient-specific plates generated through virtual surgery planning with digital models for the study group, while the control group underwent the same procedure with conventional titanium plates. Assessment criteria included the presence of malunion, infection, sensory disturbance, subjective occlusal disturbance and occlusal force in functional maximum intercuspation (MICP). Statistical analysis involved using the Chi-square test and one-way repeated measures analysis of variance. RESULTS: All parameters showed no statistically significant differences between the study and control groups, except for the enhancement in occlusal force in functional MICP, where a statistically significant difference was observed (p = 0.000). CONCLUSION: Using patient-specific plates using digital technology has demonstrated clinical effectiveness in treating mandibular fractures, offering advantages of time efficiency and benefits for less experienced surgeons. CLINICAL RELEVANCE: Patient-specific plates combined with digital technology can be clinically effective in mandibular fracture treatment.


Assuntos
Placas Ósseas , Fixação Interna de Fraturas , Fraturas Mandibulares , Titânio , Humanos , Fraturas Mandibulares/cirurgia , Titânio/química , Masculino , Feminino , Fixação Interna de Fraturas/métodos , Fixação Interna de Fraturas/instrumentação , Adulto , Resultado do Tratamento , Pessoa de Meia-Idade , Desenho Assistido por Computador , Cirurgia Assistida por Computador/métodos
2.
Int J Mol Sci ; 22(21)2021 Oct 25.
Artigo em Inglês | MEDLINE | ID: mdl-34768914

RESUMO

Our aim was to investigate the bone regeneration capacity of powder-type biphasic ceramic scaffold (BCP powder), block-type BCP (BCP block), and collagen-added block-type BCP (BCP collagen) with different concentrations of recombinant human bone morphogenetic protein 2 (rhBMP-2) in an animal model. Four rabbits were assigned to each of the following groups: no graft + rhBMP-2 (0.1/0.2 mg/mL), BCP powder + rhBMP-2 (0.1/0.2 mg/mL), BCP block + rhBMP-2 (0.1/0.2 mg/mL), and BCP collagen + rhBMP-2 (0.1/0.2 mg/mL), i.e., a total of 32 rabbits. Polycarbonate tubes (Φ 7 mm × 5 mm) for supporting scaffolds were fixed into a 7 mm round border. Subsequently, 0.1 mL of rhBMP-2 solutions with different concentrations was injected into the tubes. Both radiological and histomorphometric analyses showed that osteogenesis was not enhanced by increasing the concentration of rhBMP-2 in all groups at both 3 and 6 weeks. Radiological analysis showed that bone formation was higher in the BCP collagen group than in the BCP powder and BCP block groups at both rhBMP-2 concentrations at 3 weeks. rhBMP-2 enhanced bone formation; however, as the concentration increased, bone formation could not be enhanced infinitely. Collagen-added alloplastic graft material may be useful for mediating rapid bone formation in initial stages.


Assuntos
Doenças Ósseas/terapia , Proteína Morfogenética Óssea 2/administração & dosagem , Regeneração Óssea , Cerâmica/química , Osteogênese , Fraturas Cranianas/terapia , Alicerces Teciduais/química , Fator de Crescimento Transformador beta/administração & dosagem , Animais , Doenças Ósseas/metabolismo , Doenças Ósseas/patologia , Proteína Morfogenética Óssea 2/metabolismo , Masculino , Coelhos , Proteínas Recombinantes/administração & dosagem , Proteínas Recombinantes/metabolismo , Fraturas Cranianas/metabolismo , Fraturas Cranianas/patologia , Fator de Crescimento Transformador beta/metabolismo
3.
Int J Mol Sci ; 22(22)2021 Nov 20.
Artigo em Inglês | MEDLINE | ID: mdl-34830400

RESUMO

This study aimed to evaluate the bone regeneration capacity of a customized alloplastic material and xenograft with recombinant human bone morphogenetic protein-2 (rhBMP-2). We prepared hydroxyapatite (HA)/tricalcium phosphate (TCP) pure ceramic bone blocks made using a 3D printing system and added rhBMP-2 to both materials. In eight beagle dogs, a total of 32 defects were created on the lower jaws. The defective sites of the negative control group were left untreated (N group; 8 defects), and those in the positive control group were filled with particle-type Bio-Oss (P group; 12 defects). The defect sites in the experimental group were filled with 3D-printed synthetic bone blocks (3D group; 12 defects). Radiographic and histological evaluations were performed after healing periods of 6 and 12 weeks and showed no significant difference in new bone formation and total bone between the P and 3D groups. The 3D-printed custom HA/TCP graft with rhBMP-2 showed bone regeneration effects similar to that of particulate Bio-Oss with rhBMP-2. Through further study and development, the application of 3D-printed customized alloplastic grafts will be extended to various fields of bone regeneration.


Assuntos
Proteína Morfogenética Óssea 2/genética , Regeneração Óssea/genética , Anormalidades Maxilomandibulares/terapia , Desenvolvimento Maxilofacial/genética , Fator de Crescimento Transformador beta/genética , Animais , Proteína Morfogenética Óssea 2/farmacologia , Regeneração Óssea/efeitos dos fármacos , Substitutos Ósseos/farmacologia , Fosfatos de Cálcio/farmacologia , Cães , Durapatita/farmacologia , Humanos , Arcada Osseodentária/patologia , Anormalidades Maxilomandibulares/genética , Anormalidades Maxilomandibulares/patologia , Impressão Tridimensional , Proteínas Recombinantes/genética , Proteínas Recombinantes/farmacologia , Crânio/efeitos dos fármacos , Crânio/crescimento & desenvolvimento , Crânio/patologia , Fator de Crescimento Transformador beta/farmacologia
4.
BMC Oral Health ; 21(1): 125, 2021 03 17.
Artigo em Inglês | MEDLINE | ID: mdl-33731091

RESUMO

BACKGROUND: Chronic periodontitis is a multifactorial inflammatory disease resulting in patients exhibiting high levels of inflammatory factors causing systemic inflammatory bone destruction that may lead to osteoporosis development. The association between periodontitis and osteoporosis has been documented; however, the findings remain unclear. This study aimed to identify the association between periodontitis and osteoporosis using a cross-sectional study design and Korean Genome and Epidemiology Study (KoGES) health examinee data. METHODS: This cross-sectional study used epidemiological data from the KoGES during 2004-2016. Of 125,324 participants (age, 40-79 years), 9969 with periodontitis and 115,332 controls (without periodontitis) were selected. We analyzed the history of osteoporosis and fractures of all participants. All participants were examined according to age, sex, income group, obesity, smoking habits, alcohol consumption, and food intake. To analyze the odds ratio (OR) of periodontitis for those with osteoporosis and fractures, a logistic regression model was used. RESULTS: The adjusted odds ratio (aOR) of periodontitis for osteoporosis was 2.16 (95% confidence interval [CI], 2.01-2.31; P < 0.001). The aOR of periodontitis for any fracture was 1.54 (95% CI 1.46-1.62; P < 0.001). CONCLUSION: Osteoporosis and fractures are associated with periodontitis. Performing regular oral hygiene and examinations of bone mineral density are recommended to prevent aggravation of osteoporosis and periodontitis.


Assuntos
Osteoporose , Periodontite , Adulto , Idoso , Densidade Óssea , Estudos Transversais , Humanos , Pessoa de Meia-Idade , Higiene Bucal , Osteoporose/complicações , Osteoporose/epidemiologia , Periodontite/complicações , Periodontite/epidemiologia
5.
Int J Mol Sci ; 21(18)2020 Sep 22.
Artigo em Inglês | MEDLINE | ID: mdl-32971749

RESUMO

This study evaluated the mechanical properties and bone regeneration ability of 3D-printed pure hydroxyapatite (HA)/tricalcium phosphate (TCP) pure ceramic scaffolds with variable pore architectures. A digital light processing (DLP) 3D printer was used to construct block-type scaffolds containing only HA and TCP after the polymer binder was completely removed by heat treatment. The compressive strength and porosity of the blocks with various structures were measured; scaffolds with different pore sizes were implanted in rabbit calvarial models. The animals were observed for eight weeks, and six animals were euthanized in the fourth and eighth weeks. Then, the specimens were evaluated using radiological and histological analyses. Larger scaffold pore sizes resulted in enhanced bone formation after four weeks (p < 0.05). However, in the eighth week, a correlation between pore size and bone formation was not observed (p > 0.05). The findings showed that various pore architectures of HA/TCP scaffolds can be achieved using DLP 3D printing, which can be a valuable tool for optimizing bone-scaffold properties for specific clinical treatments. As the pore size only influenced bone regeneration in the initial stage, further studies are required for pore-size optimization to balance the initial bone regeneration and mechanical strength of the scaffold.


Assuntos
Substitutos Ósseos/química , Cerâmica/química , Teste de Materiais , Osteogênese , Impressão Tridimensional , Alicerces Teciduais/química , Animais , Linhagem Celular , Camundongos , Porosidade
6.
Int J Mol Sci ; 21(14)2020 Jul 08.
Artigo em Inglês | MEDLINE | ID: mdl-32650589

RESUMO

In this study, we evaluated the bone regenerative capability of a customizable hydroxyapatite (HA) and tricalcium phosphate (TCP) scaffold using a digital light processing (DLP)-type 3D printing system. Twelve healthy adult male beagle dogs were the study subjects. A total of 48 defects were created, with two defects on each side of the mandible in all the dogs. The defect sites in the negative control group (sixteen defects) were left untreated (the NS group), whereas those in the positive control group (sixteen defects) were filled with a particle-type substitute (the PS group). The defect sites in the experimental groups (sixteen defects) were filled with a 3D printed substitute (the 3DS group). Six dogs each were exterminated after healing periods of 4 and 8 weeks. Radiological and histomorphometrical evaluations were then performed. None of the groups showed any specific problems. In radiological evaluation, there was a significant difference in the amount of new bone formation after 4 weeks (p < 0.05) between the PS and 3DS groups. For both of the evaluations, the difference in the total amount of bone after 8 weeks was statistically significant (p < 0.05). There was no statistically significant difference in new bone between the PS and 3DS groups in both evaluations after 8 weeks (p > 0.05). The proposed HA/TCP scaffold without polymers, obtained using the DLP-type 3D printing system, can be applied for bone regeneration. The 3D printing of a HA/TCP scaffold without polymers can be used for fabricating customized bone grafting substitutes.


Assuntos
Regeneração Óssea/fisiologia , Cerâmica/farmacologia , Mandíbula/efeitos dos fármacos , Alicerces Teciduais/química , Animais , Substitutos Ósseos/farmacologia , Fosfatos de Cálcio/farmacologia , Cães , Durapatita/farmacologia , Masculino , Impressão Tridimensional
7.
J Craniofac Surg ; 30(7): e619-e622, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31157641

RESUMO

Anterior segmental osteotomy (ASO) is considered the treatment modality of choice in patients with the bimaxillary dentoalveolar protrusion. However, this meticulous surgical technique accompanies a number of possible disadvantages. The considerable time required before, during, and after the operation, limited movement of the segment, damage of the mental nerve, loss of tooth vitality, loss of a tooth or teeth, or indeed total loss of the anterior segments are those that affect the result of the surgery. Recently, the authors have devised a computer-aided surgical simulation programme and fabricated the customized osteotomy guides and the spider-shaped plates based on the programme. They were then applied to a 28-year-old patient with the complaint of a bimaxillary dentoalveolar protrusion. This approach helped to overcome several problems related to ASO reported earlier.


Assuntos
Má Oclusão/cirurgia , Osteotomia , Adulto , Feminino , Humanos , Osteotomia/instrumentação , Osteotomia/métodos , Cirurgia Assistida por Computador
8.
BMC Oral Health ; 19(1): 18, 2019 01 15.
Artigo em Inglês | MEDLINE | ID: mdl-30646896

RESUMO

BACKGROUND: Many reports have been published on orthognathic surgery (OGS) using computer-aided surgical simulation (CASS). The purpose of this study was to evaluate the accuracy of the maxillary repositioning and the stability of the maxilla in patients who underwent OGS using a newly developed CASS program, a customized osteotomy guide, and a customized miniplate. METHODS: Thirteen patients who underwent OGS from 2015 to 2017 were included. All patients underwent a bimaxillary operation. First, a skull-dentition hybrid 3D image was rendered by merging the cone beam computed tomography (CBCT) images with the dentition scan file. After virtual surgery (VS) using the FaceGide® program, patient-customized osteotomy guides and miniplates were then fabricated and used in the actual operation. To compare the VS with the actual surgery and postoperative skeletal changes, each reference point marked on the image was compared before the operation (T0) and three days (T1), four months (T2), and a year (T3) after the operation, and with the VS (Tv). The differences between ΔTv (Tv-T0) and ΔT1 (T1-T0) were statistically compared using tooth-based reference points. The superimposed images of Tv and T1 were also investigated at eight bone-based reference points. The differences between the reference points of the bone surface were examined to evaluate the stability of the miniplate on the maxilla over time. RESULTS: None of the patients experienced complications. There were no significant differences between the reference points based on the cusp tip between ΔTv and ΔT1 (p > 0.01). Additionally, there were no significant differences between the Tv and T1 values of the bone surface (p > 0.01). The mean difference in the bone surface between Tv and T1 was 1.01 ± 0.3 mm. Regarding the stability of the miniplate, there were no significant differences between the groups. The difference in the bone surface between T1 and T3 was - 0.37 ± 0.29 mm. CONCLUSIONS: VS was performed using the FaceGide® program, and customized materials produced based on the VS were applied in actual OGS. The maxilla was repositioned in almost the same manner as in the VSP plan, and the maxillary position remained stable for a year.


Assuntos
Tomografia Computadorizada de Feixe Cônico , Maxila/cirurgia , Procedimentos Cirúrgicos Ortognáticos/métodos , Cirurgia Assistida por Computador/métodos , Cefalometria , Humanos , Imageamento Tridimensional , Maxila/diagnóstico por imagem , Cirurgia Ortognática
9.
J Craniofac Surg ; 28(2): 508-512, 2017 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-28027189

RESUMO

PURPOSE: This study was designed to assess the clinical outcomes and surgical convenience of a newly designed Yang's Keyhole plate (YK plate) system for treatment of subcondyle and angle fractures of the mandible. To evaluate the system's clinical outcomes and surgical convenience, chart review and surgical simulation using a mandible replica model were performed. METHODS: The YK plate system, which is a slightly modified sliding plate, has 0.8-mm thick titanium and a widened hole in the anterior region to permit a screw head to be inserted. The clinical results and clinical convenience of the newly developed YK plate system and the existing 4-hole miniplate fixation technique were compared using a surgical simulation. Moreover, the clinical results of the patients who underwent mandibular surgery were compared during the follow-up examination periods (ie, weeks 1, 2, 4, 8, and 16). RESULTS: No critical complications in any of the 22 patients were reported during the 4-month follow-up period. The results of the assessment of clinical convenience using the surgical simulation showed that using the YK plate system was more convenient and saved time compared to using the 4-hole miniplate. CONCLUSION: The newly developed YK plate system can be applied to subcondyle and angle fractures of the mandible and can provide reliable and convenient application and use.


Assuntos
Placas Ósseas , Fixação Interna de Fraturas/métodos , Fraturas Mandibulares/cirurgia , Adulto , Parafusos Ósseos , Feminino , Humanos , Masculino , Mandíbula/cirurgia , Pessoa de Meia-Idade , Desenho de Prótese , Titânio
10.
Am J Orthod Dentofacial Orthop ; 147(3): 381-93, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25726406

RESUMO

Maxillary deficiency is a common feature in patients with repaired cleft lip and palate. Orthognathic surgery has been the conventional approach for the management of cleft-related maxillary hypoplasia. However, for patients with a severe maxillary deficiency, orthognathic surgery alone has many disadvantages, such as high relapse rates of 25% to 40%, instability, limited amount of advancement, and a highly invasive surgical technique. As an alternative treatment method, distraction osteogenesis has been used successfully in the distraction of the mandible, the maxilla, the entire midface, and the orbits as well as the cranial bones, with stable outcomes. The type of distraction device, either external or internal, can be chosen based on the surgical goals set for the patient. In this study, we report on the use of a rigid external distraction device for maxillary advancement in a 22-year-old woman with a repaired unilateral cleft lip and palate and severe maxillary hypoplasia. After the distraction osteogenesis, 2-jaw surgery was performed to correct the maxillary yaw deviation and the mandibular prognathism.


Assuntos
Fenda Labial/cirurgia , Fissura Palatina/cirurgia , Maxila/anormalidades , Procedimentos Cirúrgicos Ortognáticos/métodos , Osteogênese por Distração/métodos , Cefalometria/métodos , Fixadores Externos , Feminino , Mentoplastia/métodos , Humanos , Má Oclusão Classe III de Angle/cirurgia , Maxila/cirurgia , Osteogênese por Distração/instrumentação , Osteotomia de Le Fort/métodos , Osteotomia Sagital do Ramo Mandibular/métodos , Planejamento de Assistência ao Paciente , Prognatismo/cirurgia , Adulto Jovem
11.
J Craniofac Surg ; 25(1): 149-53, 2014 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-24406569

RESUMO

OBJECTIVE: This study compared bone healing following the use of 2 piezoelectric surgery units or conventional mechanical cutting with carbide and diamond drills to explore their future applications for bone surgery. METHODS: Subcritical-size (approximately 1.5-2 mm) calvarial defects were created in the parietal bones of adult mice. Following defect standardization, a full-thickness semicircular defect was created on the parietal bones of 12 mice divided into 4 groups: carbide bur, Surgystar, diamond bur, and Piezoelectric System. Hard tissue healing was assessed using micro-computed tomography at 1 day, 2 weeks, 4 weeks, and 8 weeks after surgery. RESULTS: At 4 weeks, the Surgystar group and Piezoelectric System group showed a significant difference from the carbide group. The Surgystar and Piezoelectric System groups did differ from the diamond group. At 8 weeks, the Surgystar and Piezoelectric System groups differed significantly from the carbide and diamond groups. The fraction of healing results over the 8 weeks demonstrated that the Surgystar group had a significantly higher bone healing percentage than did the carbide group (P = 0.001) and the diamond group (P = 0.026), but it did not differ significantly from the Piezoelectric System group (P = 0.420). CONCLUSIONS: The Surgystar and Piezoelectric System are suitable for bone osteotomy and provide faster bone healing in comparison with mechanical instrumentation.


Assuntos
Regeneração Óssea/fisiologia , Craniotomia/instrumentação , Procedimentos Cirúrgicos Minimamente Invasivos/instrumentação , Osso Parietal/fisiopatologia , Osso Parietal/cirurgia , Piezocirurgia/instrumentação , Instrumentos Cirúrgicos , Animais , Osso e Ossos/cirurgia , Masculino , Camundongos , Osteotomia/instrumentação , Resultado do Tratamento , Microtomografia por Raio-X
12.
Sci Rep ; 14(1): 3397, 2024 02 10.
Artigo em Inglês | MEDLINE | ID: mdl-38336901

RESUMO

Ridge resorption can result in insufficient bone volume for implant surgery, necessitating bone substitutes to restore the resorption area. Recent advances in computer-aided design and manufacturing enable the use of alloplastic bone graft materials with customizable compositions or shapes. This randomized study evaluated the clinical effectiveness of a customized three-dimensional (3D) printed alloplastic bone material. Sixty patients requiring guided bone regeneration for implant installation following tooth extraction due to alveolar bone resorption were recruited at two institutions. The participants were randomly allocated to either a group that received 3D-printed patient-customized bone graft material or a group that received conventional block bone graft material. Implant installation with bone harvesting was performed approximately 5 months after bone grafting. Histological and radiological assessments of the harvested bone area were performed. The experimental group had a significantly higher percent bone volume and a smaller tissue surface than the control group. Bone volume, bone surface, bone surface/volume ratio, bone surface density (bone surface/total volume), and bone mineral density did not differ significantly between groups. Patient-customized bone graft materials offer convenience and reduce patient discomfort. The findings suggest 3D-printed patient-customized bone graft materials could be used as an alternative for simpler bone grafting procedures.


Assuntos
Perda do Osso Alveolar , Substitutos Ósseos , Humanos , Transplante Ósseo/métodos , Estudos Prospectivos , Perda do Osso Alveolar/diagnóstico por imagem , Perda do Osso Alveolar/cirurgia , Regeneração Óssea , Cerâmica
13.
J Dent ; 146: 105061, 2024 07.
Artigo em Inglês | MEDLINE | ID: mdl-38729289

RESUMO

OBJECTIVES: Orthognathic surgery (OS) has evolved with technological advancements, notably through the implementation of computer-assisted orthognathic surgery (CAOS). This article aims to elucidate various types of CAOS and their efficiency and accuracy, supplemented by a thorough literature review focusing on their clinical applications in South Korea. STUDY SELECTION, DATA, AND SOURCES: A comprehensive search strategy was employed, including systematic reviews, meta-analyses, randomized controlled trials, and observational studies published until December 2023 in the PubMed, MEDLINE, and Google Scholar databases. The literature search was limited to articles written in English. RESULTS: Static CAOS demonstrated high precision, reduced operative time, and high accuracy, suggesting its potential reliability in orthognathic procedures. Dynamic CAOS presented a promising avenue for exploration, showing an accuracy comparable to that of traditional methods. The critical considerations for CAOS include accuracy, time efficiency, and cost-effectiveness. Recent studies have indicated advancements in the time efficiency of static CAOS. Static CAOS requires less equipment and is more cost-effective than dynamic CAOS. CONCLUSIONS: CAOS offers clear advantages over conventional OS in terms of surgical convenience and accuracy in implementing the surgical plan. To achieve recognition as the gold standard method for maxillofacial deformity treatment, CAOS must overcome its limitations and undergo continuous verification via well-designed studies. CLINICAL SIGNIFICANCE: The introduction of CAOS, mainly static CAOS with high precision and reduced surgical time, signifies a notable advancement in OS. However, rigorous studies are warranted to validate CAOS as the gold standard for treating maxillofacial deformities.


Assuntos
Procedimentos Cirúrgicos Ortognáticos , Cirurgia Assistida por Computador , Humanos , Cirurgia Assistida por Computador/métodos , República da Coreia , Duração da Cirurgia
14.
J Dent ; 147: 105030, 2024 08.
Artigo em Inglês | MEDLINE | ID: mdl-38685341

RESUMO

OBJECTIVES: Temporomandibular disorder (TMD) is a common condition that affects the temporomandibular joint (TMJ) and the muscles of the jaw, resulting in pain and dysfunction. TMD is affected by both behavioral and psychological factors. Digital therapeutics (DTx) can exert therapeutic effects by controlling behavioral factors through the delivery of appropriate interventions. Here, we report an open-label randomized control trial to evaluate the efficacy of DTx for TMD. METHODS: We recruited 40 participants diagnosed with TMD. Participants were randomly divided into an intervention group (DTx use, n = 20) and a control group (n = 20). The intervention group received the usual treatment process for TMD in addition to the use of the DTx. The control group received the usual treatments only. Patients in both groups were followed up for 3-4 weeks, and outcome data were collected and analyzed. RESULT: The intervention group showed a significant reduction in pain scores as measured by the numerical rating scale (NRS) (p = 0.016). Additionally, the intervention group showed a statistically significant increase in maximal mouth opening compared to the control group (p = 0.0079). However, there were no significant differences in improvement in the Jaw Functional Limitation Scale, Oral Behavior Checklist, and Patient Health Questionnaire-4 between the two groups (p = 0503, = 0.820, and = 0.943, respectively). CONCLUSION: This RCT reveals DTx potential in TMD, showing pain and mouth opening improvements with conventional treatment. But no significant changes were noted in other outcomes. The findings advocate for more extensive, long-term research to solidify DTx's role in TMD management. CLINICAL SIGNIFICANCE: This research underlines DTx potential to improve pain outcomes in TMD therapy, reinforcing its value as a complementary treatment modality.


Assuntos
Dor Facial , Medição da Dor , Transtornos da Articulação Temporomandibular , Humanos , Feminino , Masculino , Projetos Piloto , Transtornos da Articulação Temporomandibular/terapia , Adulto , Dor Facial/terapia , Resultado do Tratamento , Pessoa de Meia-Idade , Amplitude de Movimento Articular/fisiologia , Adulto Jovem , Articulação Temporomandibular/fisiopatologia , Terapia Assistida por Computador/métodos
15.
Bioengineering (Basel) ; 11(6)2024 Jun 07.
Artigo em Inglês | MEDLINE | ID: mdl-38927812

RESUMO

This study assessed AI-processed low-dose cone-beam computed tomography (CBCT) images for single-tooth diagnosis. Human-equivalent phantoms were used to evaluate CBCT image quality with a focus on the right mandibular first molar. Two CBCT machines were used for evaluation. The first CBCT machine was used for the experimental group, in which images were acquired using four protocols and enhanced with AI processing to improve quality. The other machine was used for the control group, where images were taken in one protocol without AI processing. The dose-area product (DAP) was measured for each protocol. Subjective clinical image quality was assessed twice by five dentists, with a 2-month interval in between, using 11 parameters and a six-point rating scale. Agreement and statistical significance were assessed with Fleiss' kappa coefficient and intra-class correlation coefficient. The AI-processed protocols exhibited lower DAP/field of view values than non-processed protocols, while demonstrating subjective clinical evaluation results comparable to those of non-processed protocols. The Fleiss' kappa coefficient value revealed statistical significance and substantial agreement. The intra-class correlation coefficient showed statistical significance and almost perfect agreement. These findings highlight the importance of minimizing radiation exposure while maintaining diagnostic quality as the usage of CBCT increases in single-tooth diagnosis.

16.
Bioengineering (Basel) ; 11(4)2024 Mar 27.
Artigo em Inglês | MEDLINE | ID: mdl-38671740

RESUMO

With the growing demand for orthognathic surgery and other facial treatments, the accurate identification of anatomical landmarks has become crucial. Recent advancements have shifted towards using three-dimensional radiologic analysis instead of traditional two-dimensional methods, as it allows for more precise treatment planning, primarily relying on direct identification by clinicians. However, manual tracing can be time-consuming, mainly when dealing with a large number of patients. This study compared the accuracy and reliability of identifying anatomical landmarks using artificial intelligence (AI) and manual identification. Thirty patients over 19 years old who underwent pre-orthodontic and orthognathic surgery treatment and had pre-orthodontic three-dimensional radiologic scans were selected. Thirteen anatomical indicators were identified using both AI and manual methods. The landmarks were identified by AI and four experienced clinicians, and multiple ANOVA was performed to analyze the results. The study results revealed minimal significant differences between AI and manual tracing, with a maximum deviation of less than 2.83 mm. This indicates that utilizing AI to identify anatomical landmarks can be a reliable method in planning orthognathic surgery. Our findings suggest that using AI for anatomical landmark identification can enhance treatment accuracy and reliability, ultimately benefiting clinicians and patients.

17.
J Craniofac Surg ; 24(5): 1801-5, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-24036784

RESUMO

PURPOSE: A novel maxillomandibular fixation (MMF) procedure using a skeletal anchorage screw (SAS) (in the maxilla) and an arch bar (in the mandible), which we call "hybrid maxillomandibular fixation," was explored in this study. The aims of the study were to examine the efficacy of our hybrid MMF method and to compare periodontal tissue health and occlusal rehabilitation among 3 MMF methods. MATERIALS AND METHODS: In total, 112 patients who had undergone open reduction at the Department of Oral and Maxillofacial Surgery between September 2005 and December 2012 were selected for this study. The participants were assigned to one of the following groups: SAS (maxilla), SAS (mandible), SAS-arch bar, or arch bar-arch bar. Periodontal health was evaluated using the Gingival Index, and the perioperative occlusal reproducibility was evaluated using a score of 1 to 3. Statistical analysis was performed using parametric tests (Student t test or 1-way analysis of variance followed by post hoc Tukey test). RESULTS: In the Gingival Index comparison performed 1 month after the surgery, only the group using the arch bars and wiring was significantly different from the other groups (P < 0.05). The occlusal reproducibility scores were not significantly different. The pain and discomfort of the patients were reduced in the hybrid MMF group. CONCLUSIONS: The hybrid MMF takes advantage of MMF using both arch bars and SASs for mandibular fractures. In addition, it overcomes many problems presented by previous MMF methods.


Assuntos
Fixação Interna de Fraturas/métodos , Técnicas de Fixação da Arcada Osseodentária , Fraturas Mandibulares/cirurgia , Adolescente , Adulto , Parafusos Ósseos , Feminino , Gengivite/diagnóstico , Humanos , Masculino , Pessoa de Meia-Idade , Duração da Cirurgia , Índice Periodontal , Reprodutibilidade dos Testes , Resultado do Tratamento
18.
J Craniofac Surg ; 24(6): 1927-30, 2013 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-24220375

RESUMO

The objective of this study was to demonstrate that a silk fibroin (SF) and 4-hexylresorcinol (4-HR) incorporation membrane could be used for a guided bone regeneration technique. Fourier transform infrared measurements were obtained to determine change of physical property of SF membrane by 4-HR incorporation. Two peri-implant defects, 3.0 × 5.0 mm (width × length), were prepared on the lateral side of the implant hole in the tibia of New Zealand white rabbits (n = 8). The peri-implant defect was left unfilled in the control group. Silk fibroin + 4-HR membrane was applied to the peri-implant defect in the experimental group. The 8 animals were killed at 8 weeks after implantation. Subsequently, removal torque test and histomorphometric evaluation were done. Fourier transform infrared spectroscopy showed no specific chemical interaction between 4-HR and SF. In the histomorphometric analysis, the mean bone regeneration was 18.3 ± 1.9 mm(2) in the experimental group and 9.3 ± 0.9 mm(2) in the control group (P = 0.004). In conclusion, the SF and 4-HR incorporation membrane successfully regenerated bone in the rabbit tibia peri-implant bone defect model.


Assuntos
Regeneração Óssea/fisiologia , Fibroínas/uso terapêutico , Regeneração Tecidual Guiada/instrumentação , Hexilresorcinol/uso terapêutico , Membranas Artificiais , Animais , Doenças Ósseas/patologia , Doenças Ósseas/terapia , Implantação Dentária Endóssea/métodos , Implantes Dentários , Fibroínas/química , Hexilresorcinol/química , NF-kappa B/antagonistas & inibidores , Osteogênese/fisiologia , Coelhos , Seda , Espectroscopia de Infravermelho com Transformada de Fourier , Tíbia/patologia , Tíbia/cirurgia , Fatores de Tempo , Torque
19.
J Craniofac Surg ; 24(5): 1535-8, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-24036721

RESUMO

PURPOSE: Changes in the condylar position after bilateral sagittal split ramus osteotomy (BSSO) can cause many complications, such as condylar dysfunction and increased risk of relapse. This study evaluated a simple approach for condylar repositioning in BSSO as a method to rapidly obtain the patient's centric relation (CR) bite position without prefabricated equipment. METHODS: The study subjects included 9 patients (5 men and 4 women; mean age, 23.7 years) who underwent BSSO in the Department of Oral and Maxillofacial Surgery in Hallym University hospital between December 2009 and March 2012. We performed BSSO with the condylar-repositioning method according to the patient's CR bite. RESULTS: Measurements of changes in the condylar position via radiographic images (lateral cephalometric radiographs) did not indicate significant differences after surgery (P < 0.05). In surveys of temporomandibular joint symptoms, the scores for categories (sound, pain, mouth opening limitation) also did not show any increases after surgery. CONCLUSIONS: Within a standard operating time, the condyle was effectively repositioned using the condylar-repositioning method described in this study. These results indicate this new repositioning method is simple and eliminates the need for any additional device.


Assuntos
Relação Central , Técnicas de Fixação da Arcada Osseodentária/instrumentação , Mandíbula/cirurgia , Côndilo Mandibular/anatomia & histologia , Osteotomia Sagital do Ramo Mandibular/métodos , Pontos de Referência Anatômicos/diagnóstico por imagem , Cefalometria/métodos , Assimetria Facial/cirurgia , Feminino , Humanos , Processamento de Imagem Assistida por Computador/métodos , Masculino , Côndilo Mandibular/diagnóstico por imagem , Complicações Pós-Operatórias/prevenção & controle , Prognatismo/cirurgia , Radiografia , Contenções , Transtornos da Articulação Temporomandibular/prevenção & controle , Adulto Jovem
20.
Sci Rep ; 13(1): 10603, 2023 06 30.
Artigo em Inglês | MEDLINE | ID: mdl-37391453

RESUMO

Distortion of dentition may occur in cone-beam computed tomography (CBCT) scans due to artifacts, and further imaging is frequently required to produce digital twins. The use of a plaster model is common; however, it has certain drawbacks. This study aimed to assess the feasibility of different digital dentition models over that of plaster casts. Plaster models, alginate impressions, intraoral scan (IOS) images, and CBCT images of 20 patients were obtained. The desktop model scanner was used to scan the alginate impression twice, five minutes and two hours after impression-making. Using an IOS, the full arch was scanned in segments using CS 3600 and simultaneously with i700 wireless. The digital twins obtained from the alginate impression and IOS were superimposed with those obtained from the plaster cast. The differences and distances at each reference point were measured. Scans of alginate impressions after two hours showed the greatest discrepancies, but these were all less than the CBCT voxel size of 0.39 mm. Alginate impression scans and IOS are suitable supplements to CBCT compared to the plaster model. Accuracy can be improved by scanning the alginate impression within five minutes or by intraoral scanning of the entire arch with segmentation.


Assuntos
Tomografia Computadorizada de Feixe Cônico , Dentição , Humanos , Alginatos , Artefatos , Hematopoiese Clonal
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