Facile and Widely Applicable Route to Self-Adaptive Emissivity Modulation: Energy-Saving Demonstration with Transparent Wood.

The cooling power provided by radiative cooling is unwanted during cold hours. Therefore, self-adaptive regulation is desired for radiative cooling, especially in all-weather applications. However, current routes for radiative cooling regulation are constrained by substrates and complicated processing. Here, self-adaptive radiative cooling regulation on various potential substrates (transparent wood, PET, normal glass, and cement) was achieved by a Fabry-Perot structure consisting of a silver nanowires (AgNWs) bottom layer, PMMA spacer, and W-VO2 top layer. The emissivity-modulated transparent wood (EMTW) exhibits an emissivity contrast of 0.44 (ε8-13-L = ∼0.19 and ε8-13-H = ∼0.63), which thereby yields considerable energy savings across different climate zones. The emissivity contrast can be adjusted by varying the spinning parameters during the deposition process. Positive emissivity contrast was also achieved on three other industrially relevant substrates via this facile and widely applicable route. This proves the great significance of the approach to the promotion and wide adoption of radiative cooling regulation concept in the built environment.

Love Matters: The Effect of Mating Motive on Female Food Choice.

The prevalence of obesity has been increasing globally in recent decades. Behind the phenomenon, high-fat food consumption has been conceived as an important driver. In the current study, we explored whether mating motive caused an effect on female food choice as well as the psychological mechanism underlying it. In Study 1, we recruited 64 participants from a university and asked them to complete a mating prime, after which they would finish a food choice task in which food with different flavors were shown. In Study 2, we replicated Study 1 with a different mating priming method and examined the mediating role of body shaping desire on the relation between mating motive and female food choice. Results showed that: (1) The salience of mating motive decreased female's high-fat food choice but increased male's high-fat food choice; (2) the effect of mating motive in females was robust and more salient for sweet food rather than salty food; and (3) the body shaping desire partially mediated the effect of mating motive on female food choice.

Tn6674 Is a Novel Enterococcal optrA-Carrying Multiresistance Transposon of the Tn554 Family.

The novel 12,932-bp nonconjugative multiresistance transposon Tn6674 was identified in the chromosomal DNA of a porcine Enterococcus faecalis strain. Tn6674 belongs to the Tn554 family of transposons. It shares the same arrangement of the transposase genes tnpA, tnpB, and tnpC with Tn554 However, in addition to the Tn554-associated resistance genes spc and erm(A), Tn6674 harbored the resistance genes fexA and optrA Circular forms of Tn6674 were detected and suggest the functional activity of this transposon.

Transparent, Stretchable, and Adhesive Conductive Ionic Hydrogel-Based Self-Powered Sensors for Smart Elderly Care Systems.

Nowadays, with the intensification of the aging society, the demand for elderly care and medical services is increasing and the elderly care and health systems are facing serious challenges. Therefore, it is imperative to develop a smart elderly care system to achieve real-time interaction between the elderly, the community, and medical personnel and to improve the efficiency of caring for the elderly. Here, we prepared ionic hydrogels with stable properties of high mechanical strength, high electrical conductivity, and high transparency by the one-step immersion method and used them in self-powered sensors for smart elderly care systems. The complexation of Cu2+ ions with polyacrylamide (PAAm) endows ionic hydrogels with excellent mechanical properties and electrical conductivity. Meanwhile, potassium sodium tartrate prevents the generated complex ions from precipitating into precipitates, thus ensuring the transparency of the ionic conductive hydrogel. After optimization, the transparency, tensile strength, elongation at break, and conductivity of the ionic hydrogel reached 94.1% at 445 nm, 192 kPa, 1130%, and 6.25 S/m, respectively. By processing and coding the collected triboelectric signals, a self-powered human-machine interaction system attached to the finger of the elderly was developed. The elderly can complete the transmission of distress and basic needs by simply bending their fingers, greatly reducing the pressure of inadequate medical care in an aging society. This work demonstrates the value of self-powered sensors in the field of smart elderly care systems, showing a wide implication in human-computer interface.

Plasmid Fusion and Recombination Events That Occurred during Conjugation of poxtA-Carrying Plasmids in Enterococci.

Linezolid plays a crucial role in the treatment of infections caused by multiresistant Gram-positive bacteria. The poxtA gene not only confers oxazolidinone and phenicol resistance but also decreases susceptibility to tetracycline. In this study, we investigated structural changes in mobilizable poxtA-carrying plasmids in enterococci which occurred during conjugation experiments using S1-PFGE (pulsed-field gel electrophoresis), Southern blot hybridization, and whole-genome sequencing (WGS) analysis. Two poxtA-carrying strains were identified in Enterococcus faecalis E006 and Enterococcus lactis E843, respectively. E. faecalis E006 contains the 121,520-bp conjugative plasmid pE006-121 and the 19,832-bp mobilizable poxtA-carrying plasmid pE006-19, while E. lactis E843 contains the 171,930-bp conjugative plasmid pE843-171 and the 27,847-bp mobilizable poxtA-carrying plasmid pE843-27. Moreover, both poxtA-carrying plasmids were mobilized by their respective conjugative plasmid in enterococci by plasmid fusion; one was generated by homologous recombination in E. faecalis through an identical 864-bp homologous region in the plasmids of the parental strain, while another was generated by an IS1216E-mediated plasmid integration in E. lactis, involving a replicative transposition. IMPORTANCE Until now, all the poxtA genes described in enterococci, including E. faecalis, E. faecium, and E. hirae, are plasmid-borne, suggesting that plasmids play an important role in the dissemination of the poxtA gene among enterococci. This study showed that the mobilizable poxtA-carrying plasmid could transfer with the help of conjugative plasmid in enterococci via plasmid fusion, with one generated by homologous recombination in E. faecalis, and another by replicative transposition in E. lactis. During both the fusion events, the poxtA-carrying plasmids changed from nonconjugative to conjugative, leading to the generation and enhanced dissemination of the larger phenicol-oxazolidinone-tetracycline resistance-encoding plasmids in enterococci.

Structurally Different Flavonoid Subclasses Attenuate High-Fat and High-Fructose Diet Induced Metabolic Syndrome in Rats.

Metabolic syndrome is a serious health problem worldwide. Increasing evidence indicates that flavonoid-rich foods exert beneficial effects. However, the function of flavonoids in metabolic syndrome is controversial. Here, we focus on the structural effects of flavonoids by comparing the effect of five purified subclasses of flavonoids on high-fat and high-fructose diet (HFFD) induced metabolic syndrome in vivo. Sprague-Dawley (SD) rats were fed with (i) basal diet (3.21 kcal/g) (ii) HFFD (25% lard and 25% fructose, 4.70 kcal/g), and (iii) HFFD with flavonoids representing different subclasses (2.6 mmol/kg diet): apigenin (flavones), quercetin (flavonols), genistein (isoflavones), naringenin (flavanones), and epigallocatechin gallate (flavanols) for 13 weeks. Our results showed that structurally different flavonoid subclasses prevented the HFFD-induced metabolic syndrome. Apigenin significantly decreased adipose fat and leptin levels and increased adiponectin levels. Epigallocatechin gallate and naringenin were both effective on dyslipidemia and hepatic lipid accumulations. The proinflammatory cytokines TNF-α and IL-6 were alleviated by quercetin, genistein, and naringenin. All the flavonoids exerted significant functions on improving insulin resistance and fasting glucose. In conclusion, flavonoid subclasses structurally exert antihyperlipidemic, antidiabetic, and anti-inflammatory functions by attenuating the lipid metabolism, glucose metabolism, and inflammation of metabolic syndrome.

Protective Effects of Five Structurally Diverse Flavonoid Subgroups against Chronic Alcohol-Induced Hepatic Damage in a Mouse Model.

Alcoholic liver disease (ALD) has become one of the major global health problems, with augmented morbidity and mortality. Evidence indicates that flavonoids can reduce the risk of ALD owing to their biological properties. However, the effect of structurally different flavonoid subclasses on alleviating alcohol-induced liver damage in a same model has never been studied. In this study, mice were supplemented with five kinds of flavonoid subgroups, apigenin (flavone), quercetin (flavonol), naringenin (flavanone), (-)-epigallocatechin gallate (flavanol), and genistein (isoflavone), in the same dose (0.3 mmol kg-1 body weight) and then given 50% alcohol by gastric perfusion for five consecutive weeks. The results demonstrated that genistein and naringenin had greater benefits in terms of mitigating fibrosis and apoptosis, respectively, in the liver. Lipid deposition, partial inflammatory-related factors (nuclear factor kappa B p65, cyclooxygenase-2, and interleukin-6 levels), and hepatic histopathological alterations were similarly attenuated by five kinds of flavonoids. All the flavonoids also showed different degrees of influence on protecting against alcoholic liver injury on other aspects, such as serum biochemistry makers, hepatic lipid accumulation, lipid peroxidation, antioxidant capacities, and inflammation.

"Freezing", morphing, and folding of stretchy tough hydrogels.

Highly stretchable and tough Ca-alginate/polyacrylamide hydrogels were "frozen" and folded into program-controlled shapes by exposing them to an Fe3+ ion aqueous solution. The elastic modulus of the as-made tough gels increased either in bulk or locally up to 2.90 MPa, while the toughness remained within the range from 8.18 to 4.41 kJ m-2.