Detalhe da pesquisa
1.
Quantitative Systems Pharmacology and Machine Learning: A Match Made in Heaven or Hell?
J Pharmacol Exp Ther
; 387(1): 92-99, 2023 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37652709
2.
Free Drug Theory - No Longer Just a Hypothesis?
Pharm Res
; 39(2): 213-222, 2022 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-35112229
3.
Identifying and characterising the impact of excitability in a mathematical model of tumour-immune interactions.
J Theor Biol
; 501: 110250, 2020 09 21.
Artigo
Inglês
| MEDLINE | ID: mdl-32199856
4.
Complete Substrate Inhibition of Cytochrome P450 2C8 by AZD9496, an Oral Selective Estrogen Receptor Degrader.
Drug Metab Dispos
; 46(9): 1268-1276, 2018 09.
Artigo
Inglês
| MEDLINE | ID: mdl-29921707
5.
Structural identifiability for mathematical pharmacology: models of myelosuppression.
J Pharmacokinet Pharmacodyn
; 45(1): 79-90, 2018 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-29396780
6.
Oxygen-Driven Tumour Growth Model: A Pathology-Relevant Mathematical Approach.
PLoS Comput Biol
; 11(10): e1004550, 2015 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-26517813
7.
Tumour stromal morphology impacts nanomedicine cytotoxicity in patient-derived xenografts.
Nanomedicine
; 11(5): 1247-52, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-25752857
8.
Determination of the safety and efficacy of therapeutic neutralization of tumor necrosis factor-α (TNF-α) using AZD9773, an anti-TNF-α immune Fab, in murine CLP sepsis.
Inflamm Res
; 63(2): 149-60, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-24240228
9.
Experimental and mathematical analysis of in vitro Pitavastatin hepatic uptake across species.
Xenobiotica
; 44(11): 961-74, 2014 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-25028049
10.
The design and analysis of parallel experiments to produce structurally identifiable models.
J Pharmacokinet Pharmacodyn
; 40(1): 93-100, 2013 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-23300030
11.
Skipping a pillar does not make for strong foundations: Pharmacokinetic-pharmacodynamic reasoning behind the shape of dose-response relationships in oncology.
CPT Pharmacometrics Syst Pharmacol
; 12(11): 1591-1601, 2023 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-37771203
12.
Population pharmacokinetic/pharmacodynamic modelling of the anti-TNF-α polyclonal fragment antibody AZD9773 in patients with severe sepsis.
J Pharmacokinet Pharmacodyn
; 39(6): 591-9, 2012 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-23001587
13.
The ingredients for an antimicrobial mathematical modelling broth.
Int J Antimicrob Agents
; 60(4): 106641, 2022 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-35872295
14.
How translational modeling in oncology needs to get the mechanism just right.
Clin Transl Sci
; 15(3): 588-600, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34716976
15.
Comparison of classical tumour growth models for patient derived and cell-line derived xenografts using the nonlinear mixed-effects framework.
J Biol Dyn
; 16(1): 160-185, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-35404766
16.
Step-by-step comparison of ordinary differential equation and agent-based approaches to pharmacokinetic-pharmacodynamic models.
CPT Pharmacometrics Syst Pharmacol
; 11(2): 133-148, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34399036
17.
Epstein-Barr Virus Reactivation After Paediatric Haematopoietic Stem Cell Transplantation: Risk Factors and Sensitivity Analysis of Mathematical Model.
Front Immunol
; 13: 903063, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35903096
18.
A meta-analysis of tumour response and relapse kinetics based on 34,881 patients: A question of cancer type, treatment and line of treatment.
Eur J Cancer
; 150: 42-52, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33892406
19.
Preclinical Comparison of the Blood-brain barrier Permeability of Osimertinib with Other EGFR TKIs.
Clin Cancer Res
; 27(1): 189-201, 2021 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33028591
20.
Clone Wars: Quantitatively Understanding Cancer Drug Resistance.
JCO Clin Cancer Inform
; 4: 938-946, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-33112660