Detalhe da pesquisa
1.
Implementing of Fourier Deconvolution Multiplexing to Fast Polarity Switching Miniaturized Ion Mobility Spectrometer.
Anal Chem
; 96(6): 2360-2368, 2024 Feb 13.
Artigo
Inglês
| MEDLINE | ID: mdl-38289229
2.
SAR exploration at the C-3 position of tetrahydro-ß-carboline sstr3 antagonists.
Bioorg Med Chem Lett
; 26(6): 1529-1535, 2016 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26898814
3.
Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist.
Bioorg Med Chem Lett
; 21(8): 2330-4, 2011 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21439820
4.
Discovery of AG-270, a First-in-Class Oral MAT2A Inhibitor for the Treatment of Tumors with Homozygous MTAP Deletion.
J Med Chem
; 64(8): 4430-4449, 2021 04 22.
Artigo
Inglês
| MEDLINE | ID: mdl-33829783
5.
Optimization of privileged structures for selective and potent melanocortin subtype-4 receptor ligands.
Bioorg Med Chem Lett
; 20(15): 4483-6, 2010 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20598533
6.
Discovery of potent, selective, and orally bioavailable 3H-spiro[isobenzofuran-1,4'-piperidine] based melanocortin subtype-4 receptor agonists.
Bioorg Med Chem Lett
; 20(16): 4895-900, 2010 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-20621473
7.
Discovery of highly potent and efficacious MC4R agonists with spiroindane N-Me-1,2,4-triazole privileged structures for the treatment of obesity.
Bioorg Med Chem Lett
; 20(22): 6524-32, 2010 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-20933410
8.
Discovery of a spiroindane based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor agonist.
Bioorg Med Chem Lett
; 20(7): 2106-10, 2010 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20207541
9.
Spiroindane based amides as potent and selective MC4R agonists for the treatment of obesity.
Bioorg Med Chem Lett
; 20(15): 4399-405, 2010 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20598882
10.
Effects of pyrolysis conditions on migration and distribution of biochar nitrogen in the soil-plant-atmosphere system.
Sci Total Environ
; 723: 138006, 2020 Jun 25.
Artigo
Inglês
| MEDLINE | ID: mdl-32222503
11.
Contributions and mechanisms of components in modified biochar to adsorb cadmium in aqueous solution.
Sci Total Environ
; 733: 139320, 2020 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32446077
12.
Lack of protection with a novel, selective melanocortin receptor subtype-4 agonist RY767 in a rat transient middle cerebral artery occlusion stroke model.
Pharmacology
; 83(1): 38-44, 2009.
Artigo
Inglês
| MEDLINE | ID: mdl-19052481
13.
Synthesis and SAR of potent and orally bioavailable tert-butylpyrrolidine archetype derived melanocortin subtype-4 receptor modulators.
Bioorg Med Chem Lett
; 18(11): 3242-7, 2008 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-18479920
14.
Application of the 15N tracer method to study the effect of pyrolysis temperature and atmosphere on the distribution of biochar nitrogen in the biomass-biochar-plant system.
Sci Total Environ
; 622-623: 79-87, 2018 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29202371
15.
Development of a pharmaceutical cocrystal of a monophosphate salt with phosphoric acid.
Chem Commun (Camb)
; (4): 419-21, 2007 Jan 28.
Artigo
Inglês
| MEDLINE | ID: mdl-17220990
16.
Structure-activity relationship of linear tetrapeptides Tic-DPhe-Arg-Trp-NH2 at the human melanocortin-4 receptor and effects on feeding behaviors in rat.
Peptides
; 26(10): 2017-25, 2005 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-15993513
17.
Discovery of MK-1421, a Potent, Selective sstr3 Antagonist, as a Development Candidate for Type 2 Diabetes.
ACS Med Chem Lett
; 6(5): 513-7, 2015 May 14.
Artigo
Inglês
| MEDLINE | ID: mdl-26005524
18.
Design and pharmacology of N-[(3R)-1,2,3,4-tetrahydroisoquinolinium- 3-ylcarbonyl]-(1R)-1-(4-chlorobenzyl)- 2-[4-cyclohexyl-4-(1H-1,2,4-triazol- 1-ylmethyl)piperidin-1-yl]-2-oxoethylamine (1), a potent, selective, melanocortin subtype-4 receptor agonist.
J Med Chem
; 45(21): 4589-93, 2002 Oct 10.
Artigo
Inglês
| MEDLINE | ID: mdl-12361385
19.
Investigation of Cardiovascular Effects of Tetrahydro-ß-carboline sstr3 antagonists.
ACS Med Chem Lett
; 5(7): 748-53, 2014 Jul 10.
Artigo
Inglês
| MEDLINE | ID: mdl-25050159
20.
Stimulation of Glucose-Dependent Insulin Secretion by a Potent, Selective sst3 Antagonist.
ACS Med Chem Lett
; 3(4): 289-93, 2012 Apr 12.
Artigo
Inglês
| MEDLINE | ID: mdl-24900466