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1.
Int J Surg Case Rep ; 77: 930-933, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33221137

RESUMO

INTRODUCTION: The lunotriquetral coalition is the fusion of the lunate and triquetral bones of the wrist and is the most frequent carpal coalition type. It is frequently asymptomatic and discovered as an incidental due to chronic wrist pain, trauma, or fracture. This case aims to present an unusual unilateral lunotriquetral coalition and clinical significance for diagnosis and treatment. PRESENTATION OF CASE: In this case, we presented a 37-year-old male who exhibited with right-sided trauma and wrist pain. He was diagnosed to had a type III complete osseous lunotriquetral coalition on the right side and detected by plain radiography and CT without lytic, destructive, and sclerotic lesions. DISCUSSION: An avulsion fracture was recognized in the distal end of the right radius. A fragmented fracture was identified in the scaphoid bone, and an internal fixator extending from scaphoid bone to lunate bone. The internal fixators were observed among the lunate, capitate, and distal end of the radius bones. The plain anteroposterior, lateral radiograph and CT of the right wrist exhibited a right-sided unilateral type III osseous coalition between the lunate and triquetrum bones. CONCLUSION: Knowledge of type III complete fusion is essential to the proper diagnosis and management of this variation when a subject exhibits unexplained wrist pain, trauma, or fracture. It should be noted that plain radiographs and CT can provide an accurate diagnosis in type III complete lunotriquetral coalition without pathological evidence.

2.
Free Radic Res ; 49(8): 1004-14, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25791066

RESUMO

Melatonin is known to reduce detrimental effects of free radicals by stimulating antioxidant enzymes; however, its role has not been studied in 6-hydroxydopamine (6-OHDA)-induced rat model of Parkinson's disease (PD). Therefore, we aimed to elucidate the effects of melatonin on motor activity and oxidative stress parameters in 6-OHDA-induced rat model of PD. Three-month-old male Wistar rats were divided into 5 groups: vehicle (V), melatonin-treated (M), 6-OHDA-injected (6-OHDA), 6-OHDA-injected + melatonin-treated (6-OHDA-Mel), and melatonin-treated + 6-OHDA-injected (Mel-6-OHDA) group. Melatonin was administered intraperitoneally at a dose of 10 mg/kg/day for 30 days in M and Mel-6-OHDA groups, for 7 days in 6-OHDA-Mel group. Rats received a unilateral stereotaxic injection of 6-OHDA into the right medial forebrain bundle. The 6-OHDA-Mel group started receiving melatonin when experimental PD was created and the treatment was continued for 7 days. In the Mel-6-OHDA group, experimental PD was created on the 23rd day of melatonin treatment and continued for the remaining 7 days. Locomotor activity decreased in 6-OHDA group compared with that in vehicle group; however, melatonin treatment did not improve this impairment. 6-OHDA injection caused an obvious reduction in tyrosine-hydroxylase-positive dopaminergic neuron viability as determined by immunohistochemistry. Melatonin supplementation decreased dopaminergic neuron death in 6-OHDA-Mel and Mel-6-OHDA groups compared with that in 6-OHDA group. Biochemical analysis confirmed the beneficial effects of melatonin displaying higher superoxide dismutase, catalase, and glutathione peroxidase activities and lower lipid peroxidation in substantia nigra samples in comparison to non-treated 6-OHDA group. Starting melatonin treatment before creating experimental PD was more effective on observed changes.


Assuntos
Sequestradores de Radicais Livres/farmacologia , Melatonina/farmacologia , Fármacos Neuroprotetores/farmacologia , Doença de Parkinson Secundária/tratamento farmacológico , Animais , Catalase/metabolismo , Avaliação Pré-Clínica de Medicamentos , Glutationa Peroxidase/metabolismo , Peroxidação de Lipídeos , Masculino , Feixe Prosencefálico Mediano/patologia , Atividade Motora , Oxidopamina , Doença de Parkinson Secundária/induzido quimicamente , Doença de Parkinson Secundária/metabolismo , Ratos Wistar , Substância Negra/enzimologia , Superóxido Dismutase/metabolismo , Tirosina 3-Mono-Oxigenase/metabolismo
3.
Ann Anat ; 185(2): 179-82, 2003 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-12725442

RESUMO

A high origin of the radial artery accompanied by muscular and neural abnormalities (three-headed biceps brachii, absence of the palmaris longus muscle, and communication between median and musculocutaneous nerves) were encountered during the dissection of a 25-year-old male cadaver. Co-existence of these variations has not, to our knowledge, been reported in the available literature.


Assuntos
Anormalidades Múltiplas/patologia , Nervo Mediano/anormalidades , Músculo Esquelético/anormalidades , Artéria Radial/anormalidades , Adulto , Cadáver , Humanos , Masculino
4.
Morphologie ; 88(282): 160-3, 2004 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-15641655

RESUMO

An abnormal abductor pollicis longus muscle was encountered bilaterally during the dissection of the upper limb of a 26-year-old male cadaver. In the left side, the abductor pollicis longus had seven tendon slips. The medial two inserted into the abductor pollicis brevis, the other five inserted into the base of the first metacarpal bone. In the right side of the case, the abductor pollicis longus was consisted of three bellies. The lateral belly's tendon was the main abductor pollicis longus tendon and inserted into the base of the first metacarpal bone. The medial belly inserted into the abductor pollicis brevis. Between these muscle bellies, there was an intermediate belly. Its tendon was split into two thin slips and inserted into both the abductor pollicis brevis and the opponens pollicis muscles. The number of such accessory tendons has a functional significance in the development of de Quervain's stenosing tendovaginitis and possibly also has a practical significance. This paper is the first to describe seven tendons of the abductor pollicis longus and extensor pollicis brevis in the same compartment.


Assuntos
Músculo Esquelético/anatomia & histologia , Polegar , Adulto , Cadáver , Humanos , Masculino
7.
Surg Radiol Anat ; 23(5): 331-4, 2001 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-11824133

RESUMO

The canal of the posterior ampullar nerve is located between the inferior part of the internal acoustic meatus and ampulla of the posterior semicircular canal. It permits a more accurate localisation of the underlying labyrinth in inner-ear surgery. An anatomical and radiological study was undertaken to determine the importance the relationship between the canal and the labyrinth. Ten dry and 10 cadaveric temporal bone dissections, together with 20 high resolution CT scans of the same temporal bones were studied in an attempt to describe the anatomy of the canal of the posterior ampullar nerve. The length of the canal of the posterior ampullar nerve, the length of internal acoustic meatus, and distances from porus acusticus to the singular foramen and the transverse crest, and from the singular foramen to the vestibule and transverse crest, and from operculum to the sigmoid sinus and to the porus acusticus were measured. During the transmeatal posterior cranial fossa approach using the canal of the posterior ampullar nerve as a landmark enables more bone to be safely removed from the internal acoustic meatus thus preserving hearing.


Assuntos
Canais Semicirculares/anatomia & histologia , Osso Temporal/anatomia & histologia , Osso Temporal/diagnóstico por imagem , Nervo Vestibular/anatomia & histologia , Cadáver , Humanos , Osso Petroso/anatomia & histologia , Osso Petroso/diagnóstico por imagem , Probabilidade , Valores de Referência , Sensibilidade e Especificidade , Tomografia Computadorizada por Raios X
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