Pesquisa | Secretaria de Estado da Saúde

1.

An Engineered CRISPR-Cas9 Mouse Line for Simultaneous Readout of Lineage Histories and Gene Expression Profiles in Single Cells.

Bowling, Sarah; Sritharan, Duluxan; Osorio, Fernando G; Nguyen, Maximilian; Cheung, Priscilla; Rodriguez-Fraticelli, Alejo; Patel, Sachin; Yuan, Wei-Chien; Fujiwara, Yuko; Li, Bin E; Orkin, Stuart H; Hormoz, Sahand; Camargo, Fernando D.

Cell ; 181(6): 1410-1422.e27, 2020 06 11.

Artigo Inglês | MEDLINE | ID: mdl-32413320

2.

An Engineered CRISPR-Cas9 Mouse Line for Simultaneous Readout of Lineage Histories and Gene Expression Profiles in Single Cells.

Bowling, Sarah; Sritharan, Duluxan; Osorio, Fernando G; Nguyen, Maximilian; Cheung, Priscilla; Rodriguez-Fraticelli, Alejo; Patel, Sachin; Yuan, Wei-Chien; Fujiwara, Yuko; Li, Bin E; Orkin, Stuart H; Hormoz, Sahand; Camargo, Fernando D.

Cell ; 181(7): 1693-1694, 2020 Jun 25.

Artigo Inglês | MEDLINE | ID: mdl-32589959

3.

The architecture of parent-of-origin effects in mice.

Mott, Richard; Yuan, Wei; Kaisaki, Pamela; Gan, Xiangchao; Cleak, James; Edwards, Andrew; Baud, Amelie; Flint, Jonathan.

Cell ; 156(1-2): 332-42, 2014 Jan 16.

Artigo Inglês | MEDLINE | ID: mdl-24439386

4.

Targeting myeloid chemotaxis to reverse prostate cancer therapy resistance.

Guo, Christina; Sharp, Adam; Gurel, Bora; Crespo, Mateus; Figueiredo, Ines; Jain, Suneil; Vogl, Ursula; Rekowski, Jan; Rouhifard, Mahtab; Gallagher, Lewis; Yuan, Wei; Carreira, Suzanne; Chandran, Khobe; Paschalis, Alec; Colombo, Ilaria; Stathis, Anastasios; Bertan, Claudia; Seed, George; Goodall, Jane; Raynaud, Florence; Ruddle, Ruth; Swales, Karen E; Malia, Jason; Bogdan, Denisa; Tiu, Crescens; Caldwell, Reece; Aversa, Caterina; Ferreira, Ana; Neeb, Antje; Tunariu, Nina; Westaby, Daniel; Carmichael, Juliet; Fenor de la Maza, Maria Dolores; Yap, Christina; Matthews, Ruth; Badham, Hannah; Prout, Toby; Turner, Alison; Parmar, Mona; Tovey, Holly; Riisnaes, Ruth; Flohr, Penny; Gil, Jesus; Waugh, David; Decordova, Shaun; Schlag, Anna; Calì, Bianca; Alimonti, Andrea; de Bono, Johann S.

Nature ; 623(7989): 1053-1061, 2023 Nov.

Artigo Inglês | MEDLINE | ID: mdl-37844613

5.

Identification of the potassium-binding site in serotonin transporter.

Hellsberg, Eva; Boytsov, Danila; Chen, Qingyang; Niello, Marco; Freissmuth, Michael; Rudnick, Gary; Zhang, Yuan-Wei; Sandtner, Walter; Forrest, Lucy R.

Proc Natl Acad Sci U S A ; 121(18): e2319384121, 2024 Apr 30.

Artigo Inglês | MEDLINE | ID: mdl-38652746

6.

Spin current from sub-terahertz-generated antiferromagnetic magnons.

Li, Junxue; Wilson, C Blake; Cheng, Ran; Lohmann, Mark; Kavand, Marzieh; Yuan, Wei; Aldosary, Mohammed; Agladze, Nikolay; Wei, Peng; Sherwin, Mark S; Shi, Jing.

Nature ; 578(7793): 70-74, 2020 02.

Artigo Inglês | MEDLINE | ID: mdl-31988510

7.

m⁶ A deposition is regulated by PRMT1-mediated arginine methylation of METTL14 in its disordered C-terminal region.

Wang, Zhihao; Pan, Zhicheng; Adhikari, Samir; Harada, Bryan T; Shen, Lei; Yuan, Wei; Abeywardana, Tharindumala; Al-Hadid, Qais; Stark, Jeremy M; He, Chuan; Lin, Lan; Yang, Yanzhong.

EMBO J ; 40(5): e106309, 2021 03 01.

Artigo Inglês | MEDLINE | ID: mdl-33459381

8.

Proteomic Characterization Identifies Clinically Relevant Subgroups of Gastrointestinal Stromal Tumors.

Sun, Mingjun; Tong, Yexin; Yuan, Wei; Wang, Yunzhi; Pu, Yan; Huang, Wen; Lv, Boqiong; Xu, Chen; Jiang, Wei; Luo, Rongkui; Fang, Rundong; Tang, Shaoshuai; Ren, Lei; Wang, Jiachen; Feng, Jinwen; Sun, Cheng; Shen, Kuntang; He, Fuchu; Hou, Yingyong; Ding, Chen.

Gastroenterology ; 166(3): 450-465.e33, 2024 Mar.

Artigo Inglês | MEDLINE | ID: mdl-37995868

9.

Electrical switching of the edge current chirality in quantum anomalous Hall insulators.

Yuan, Wei; Zhou, Ling-Jie; Yang, Kaijie; Zhao, Yi-Fan; Zhang, Ruoxi; Yan, Zijie; Zhuo, Deyi; Mei, Ruobing; Wang, Yang; Yi, Hemian; Chan, Moses H W; Kayyalha, Morteza; Liu, Chao-Xing; Chang, Cui-Zu.

Nat Mater ; 23(1): 58-64, 2024 Jan.

Artigo Inglês | MEDLINE | ID: mdl-37857889

10.

H3K9 methylation drives resistance to androgen receptor-antagonist therapy in prostate cancer.

Baratchian, Mehdi; Tiwari, Ritika; Khalighi, Sirvan; Chakravarthy, Ankur; Yuan, Wei; Berk, Michael; Li, Jianneng; Guerinot, Amy; de Bono, Johann; Makarov, Vladimir; Chan, Timothy A; Silverman, Robert H; Stark, George R; Varadan, Vinay; De Carvalho, Daniel D; Chakraborty, Abhishek A; Sharifi, Nima.

Proc Natl Acad Sci U S A ; 119(21): e2114324119, 2022 05 24.

Artigo Inglês | MEDLINE | ID: mdl-35584120

11.

Atomic-scale probing of heterointerface phonon bridges in nitride semiconductor.

Li, Yue-Hui; Qi, Rui-Shi; Shi, Ruo-Chen; Hu, Jian-Nan; Liu, Zhe-Tong; Sun, Yuan-Wei; Li, Ming-Qiang; Li, Ning; Song, Can-Li; Wang, Lai; Hao, Zhi-Biao; Luo, Yi; Xue, Qi-Kun; Ma, Xu-Cun; Gao, Peng.

Proc Natl Acad Sci U S A ; 119(8)2022 Feb 22.

Artigo Inglês | MEDLINE | ID: mdl-35181607

12.

Nature-Inspired Photocatalytic Azo Bond Cleavage with Red Light.

Zhao, Zijian; Li, Jili; Yuan, Wei; Cheng, Dajiao; Ma, Suze; Li, Ye-Fei; Shi, Zhang-Jie; Hu, Ke.

J Am Chem Soc ; 146(2): 1364-1373, 2024 Jan 17.

Artigo Inglês | MEDLINE | ID: mdl-38082478

13.

Asymmetric Cross-Coupling of Aldehydes with Diverse Carbonyl or Iminyl Compounds by Photoredox-Mediated Cobalt Catalysis.

Chi, Zhiyong; Liao, Jia-Bin; Cheng, Xiuliang; Ye, Ziqi; Yuan, Wei; Lin, Yu-Mei; Gong, Lei.

J Am Chem Soc ; 146(15): 10857-10867, 2024 Apr 17.

Artigo Inglês | MEDLINE | ID: mdl-38587540

14.

Orosomucoid 2 upregulation mediates liver injury-induced colorectal cancer liver metastasis by promoting EMT and cell migration.

Wei, Xundong; Wang, Lei; Yang, Bing; Ma, Yuanyuan; Yuan, Wei; Ma, Jie.

Cancer Sci ; 2024 Mar 12.

Artigo Inglês | MEDLINE | ID: mdl-38475962

15.

Preclinical testing of CT1113, a novel USP28 inhibitor, for the treatment of T-cell acute lymphoblastic leukaemia.

Xu, Jieyu; Peng, Jin; Sun, Shu; Wang, Donghai; Yuan, Wei; Yang, Xueying; Shi, Ting; Wang, Rong; Liu, Hudan; Zhang, Pumin; Zhu, Hong-Hu.

Br J Haematol ; 2024 Apr 29.

Artigo Inglês | MEDLINE | ID: mdl-38685813

16.

Extracellular matrix stiffness and tumor-associated macrophage polarization: new fields affecting immune exclusion.

Yu, Ke-Xun; Yuan, Wei-Jie; Wang, Hui-Zhen; Li, Yong-Xiang.

Cancer Immunol Immunother ; 73(6): 115, 2024 May 02.

Artigo Inglês | MEDLINE | ID: mdl-38693304

17.

A High-Voltage-Specialized Direct-Current Triboelectric Nanogenerator for Air Purification.

Shi, Jianxun; Zhao, Zhihao; Gao, Yikui; Yuan, Wei; Ma, Wenlong; Zhang, Jiayue; Zhang, Baofeng; Liu, Dongyang; Wang, Jie.

Small ; : e2311930, 2024 Mar 03.

Artigo Inglês | MEDLINE | ID: mdl-38433391

18.

MetBil as a novel molecular regulator in ischemia-induced cardiac fibrosis via METTL3-mediated m6A modification.

Zhuang, Yuting; Li, Tingting; Hu, Xiaoxi; Xie, Yilin; Pei, Xinyu; Wang, Chaoqun; Li, Yuyang; Liu, Junwu; Tian, Zhongrui; Zhang, Xiaowen; Peng, Lili; Meng, Bo; Wu, Hao; Yuan, Wei; Pan, Zhenwei; Lu, Yanjie.

FASEB J ; 37(3): e22797, 2023 03.

Artigo Inglês | MEDLINE | ID: mdl-36753405

19.

Radix Bupleuri-Radix Paeoniae Alba Inhibits the Development of Hepatocellular Carcinoma through Activation of the PTEN/PD-L1 Axis within the Immune Microenvironment.

Zhang, Fan; Zhou, Kun; Yuan, Wei; Sun, Kewei.

Nutr Cancer ; 76(1): 63-79, 2024.

Artigo Inglês | MEDLINE | ID: mdl-37909316

20.

Total Synthesis of Quebrachamine and Kopsiyunnanine D.

Liu, Hui; Yuan, Wei; Ran, Meng-Yan; Wei, Gang; Zhao, Yi; Liao, Zhi-Qiang; Liang, Hong; Chen, Zhen-Feng; Wang, Fang-Xin.

J Org Chem ; 89(8): 5905-5910, 2024 Apr 19.

Artigo Inglês | MEDLINE | ID: mdl-38579179

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An Engineered CRISPR-Cas9 Mouse Line for Simultaneous Readout of Lineage Histories and Gene Expression Profiles in Single Cells.

An Engineered CRISPR-Cas9 Mouse Line for Simultaneous Readout of Lineage Histories and Gene Expression Profiles in Single Cells.

The architecture of parent-of-origin effects in mice.

Targeting myeloid chemotaxis to reverse prostate cancer therapy resistance.

Identification of the potassium-binding site in serotonin transporter.

Spin current from sub-terahertz-generated antiferromagnetic magnons.

m⁶ A deposition is regulated by PRMT1-mediated arginine methylation of METTL14 in its disordered C-terminal region.

Proteomic Characterization Identifies Clinically Relevant Subgroups of Gastrointestinal Stromal Tumors.

Electrical switching of the edge current chirality in quantum anomalous Hall insulators.

H3K9 methylation drives resistance to androgen receptor-antagonist therapy in prostate cancer.

Atomic-scale probing of heterointerface phonon bridges in nitride semiconductor.

Nature-Inspired Photocatalytic Azo Bond Cleavage with Red Light.

Asymmetric Cross-Coupling of Aldehydes with Diverse Carbonyl or Iminyl Compounds by Photoredox-Mediated Cobalt Catalysis.

Orosomucoid 2 upregulation mediates liver injury-induced colorectal cancer liver metastasis by promoting EMT and cell migration.

Preclinical testing of CT1113, a novel USP28 inhibitor, for the treatment of T-cell acute lymphoblastic leukaemia.

Extracellular matrix stiffness and tumor-associated macrophage polarization: new fields affecting immune exclusion.

A High-Voltage-Specialized Direct-Current Triboelectric Nanogenerator for Air Purification.

MetBil as a novel molecular regulator in ischemia-induced cardiac fibrosis via METTL3-mediated m6A modification.

Radix Bupleuri-Radix Paeoniae Alba Inhibits the Development of Hepatocellular Carcinoma through Activation of the PTEN/PD-L1 Axis within the Immune Microenvironment.

Total Synthesis of Quebrachamine and Kopsiyunnanine D.