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1.
Hepatogastroenterology ; 50 Suppl 2: ccxlix-ccli, 2003 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-15244192

RESUMO

Mesenchymal Hamartoma (MH) of the liver constitutes the third or the fourth most common tumour of the liver in childhood and occurs most commonly in the first two years of life. It is often misdiagnosed clinically as a malignant tumour because of its rapid increase in size within a short period of time, or as a hepatic collections or abscess because of its cystic appearance. Although a benign lesion, MH may cause heart failure due to arteriovenous shunts, or death as a result of respiratory complications. A typical case of MH was recently encountered in a 6-years-old-boy. The patient presented with progres sive abdominal distension; surgery revealed a large mass arising from the right lobe of the liver. The mass was predominantly formed by fluid collections. Loose mesenchymal tissue and branched, tortuous bile ducts were the key diagnostic features. When predominantly cystic, MH may mimic lymphangioma both grossly and microscopically. Prudent examination of the cystic structures can establish a correct diagnosis.


Assuntos
Hamartoma/diagnóstico , Hepatopatias/diagnóstico , Criança , Hamartoma/cirurgia , Humanos , Hepatopatias/cirurgia , Masculino
2.
Pathologica ; 98(3): 181-3, 2006 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-17036947

RESUMO

Sarcomatoid renal cell carcinoma (SRCC) is an uncommon, aggressive renal cell carcinoma (RCC) accounting for 1.2% to 12.3% of renal cell carcinomas. SRCC may arise from any RCC subtype as it probably results from the de-differentiation of any renal epithelial malignancy. SRCC is characterised by a rapid progression and high metastatic rate. Currently there is no specific effective treatment for it. We report a new case of a 32-year-old man presented with two months backache. Ultrasound revealed a 7.5 cm heterogeneous mass at the inferior pole of the left kidney. A nephrectomy was performed. Histological study diagnosed a sarcomatoid renal cell carcinoma. The patient was doing well 6 months after initial surgery and then was lost to follow-up.


Assuntos
Biomarcadores Tumorais/análise , Carcinoma de Células Renais/patologia , Neoplasias Renais/patologia , Actinas/análise , Adulto , Carcinoma de Células Renais/química , Proliferação de Células , Humanos , Imuno-Histoquímica , Queratinas/análise , Neoplasias Renais/química , Masculino , Vimentina/análise
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