Detalhe da pesquisa
1.
Optical Mapping of cAMP Signaling at the Nanometer Scale.
Cell
; 182(6): 1519-1530.e17, 2020 09 17.
Artigo
Inglês
| MEDLINE | ID: mdl-32846156
2.
Optical Mapping of cAMP Signaling at the Nanometer Scale.
Cell
; 184(10): 2793, 2021 May 13.
Artigo
Inglês
| MEDLINE | ID: mdl-33989549
3.
The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration under stress conditions.
PLoS Biol
; 22(4): e3002582, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38683874
4.
Functional modulation of PTH1R activation and signaling by RAMP2.
Proc Natl Acad Sci U S A
; 119(32): e2122037119, 2022 08 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35914163
5.
ß-Arrestin biosensors reveal a rapid, receptor-dependent activation/deactivation cycle.
Nature
; 531(7596): 661-4, 2016 Mar 31.
Artigo
Inglês
| MEDLINE | ID: mdl-27007855
6.
Stepwise activation of a class C GPCR begins with millisecond dimer rearrangement.
Proc Natl Acad Sci U S A
; 116(20): 10150-10155, 2019 05 14.
Artigo
Inglês
| MEDLINE | ID: mdl-31023886
7.
Constitutive activation of PKA catalytic subunit in adrenal Cushing's syndrome.
N Engl J Med
; 370(11): 1019-28, 2014 Mar 13.
Artigo
Inglês
| MEDLINE | ID: mdl-24571724
8.
Single-molecule analysis of fluorescently labeled G-protein-coupled receptors reveals complexes with distinct dynamics and organization.
Proc Natl Acad Sci U S A
; 110(2): 743-8, 2013 Jan 08.
Artigo
Inglês
| MEDLINE | ID: mdl-23267088
9.
Comparison of the activation kinetics of the M3 acetylcholine receptor and a constitutively active mutant receptor in living cells.
Mol Pharmacol
; 82(2): 236-45, 2012 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-22564786
10.
ß-arrestin1 and 2 exhibit distinct phosphorylation-dependent conformations when coupling to the same GPCR in living cells.
Nat Commun
; 13(1): 5638, 2022 09 26.
Artigo
Inglês
| MEDLINE | ID: mdl-36163356
11.
Calcium-dependent membrane association sensitizes soluble guanylyl cyclase to nitric oxide.
Nat Cell Biol
; 4(4): 307-11, 2002 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-11887187
12.
FRET-based sensors for the human M1-, M3-, and M5-acetylcholine receptors.
Bioorg Med Chem
; 19(3): 1048-54, 2011 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20716489
13.
Determination of G-protein-coupled receptor oligomerization by molecular brightness analyses in single cells.
Nat Protoc
; 16(3): 1419-1451, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33514946
14.
Site-specific, orthogonal labeling of proteins in intact cells with two small biarsenical fluorophores.
Bioconjug Chem
; 21(5): 853-9, 2010 May 19.
Artigo
Inglês
| MEDLINE | ID: mdl-20429545
15.
Development of a Conformational Histamine H3 Receptor Biosensor for the Synchronous Screening of Agonists and Inverse Agonists.
ACS Sens
; 5(6): 1734-1742, 2020 06 26.
Artigo
Inglês
| MEDLINE | ID: mdl-32397705
16.
A universal bioluminescence resonance energy transfer sensor design enables high-sensitivity screening of GPCR activation dynamics.
Commun Biol
; 1: 105, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-30271985
17.
Single-Molecule Microscopy Reveals Dynamic FLNA Interactions Governing SSTR2 Clustering and Internalization.
Endocrinology
; 159(8): 2953-2965, 2018 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29931263
18.
FRET Studies of Quinolone-Based Bitopic Ligands and Their Structural Analogues at the Muscarinic M1 Receptor.
ACS Chem Biol
; 12(3): 833-843, 2017 03 17.
Artigo
Inglês
| MEDLINE | ID: mdl-28117571
19.
Synaptic localization of nitric oxide synthase and soluble guanylyl cyclase in the hippocampus.
J Neurosci
; 22(20): 8961-70, 2002 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-12388603
20.
PKA catalytic subunit mutations in adrenocortical Cushing's adenoma impair association with the regulatory subunit.
Nat Commun
; 5: 5680, 2014 Dec 05.
Artigo
Inglês
| MEDLINE | ID: mdl-25477193