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1.
Artigo em Russo | MEDLINE | ID: mdl-9341010

RESUMO

The presence of correlation between the quantitative content of individual carboxylic acids and aromatic compounds of microbial origin in feces and the degree of the antagonistic activity of feces was proved in experiments on conventional laboratory rats receiving therapeutic doses of tetracyclin and pefloxacin for 8 days. Antagonistic activity was regarded as one of the factors of the colonization resistance of the intestine to the invasion of opportunistic microorganisms, and microbial metabolites studied in this work were regarded as factors contributing to the persistence of these microorganisms.


Assuntos
4-Quinolonas , Infecções por Escherichia coli/microbiologia , Fluoroquinolonas , Gastroenteropatias/microbiologia , Infecções por Klebsiella/microbiologia , Infecções Oportunistas/microbiologia , Infecções por Pseudomonas/microbiologia , Infecções Estafilocócicas/microbiologia , Staphylococcus epidermidis , Animais , Antibacterianos/uso terapêutico , Anti-Infecciosos/uso terapêutico , Antibiose , Infecções por Escherichia coli/tratamento farmacológico , Fezes/química , Fezes/microbiologia , Gastroenteropatias/tratamento farmacológico , Infecções por Klebsiella/tratamento farmacológico , Masculino , Infecções Oportunistas/tratamento farmacológico , Infecções por Pseudomonas/tratamento farmacológico , Quinolonas/uso terapêutico , Ratos , Ratos Wistar , Infecções Estafilocócicas/tratamento farmacológico , Tetraciclina/uso terapêutico , Pefloxacina
2.
Antibiot Khimioter ; 43(4): 40-2, 1998.
Artigo em Russo | MEDLINE | ID: mdl-9606504

RESUMO

Two hundred and sixty eight microbial strains were tested for their antibiotic susceptibility. Azithromycin (sumamed) was shown to have an efficient inhibitory action on pneumococci, streptococci and hemophilic bacilli. Doxycycline and gentamicin were not sufficiently active against gram-positive cocci, the same as trimethoprime/sulfamethoxazole which was equally not sufficiently active against hemophilic bacilli. Adequate therapy of bronchopulmonary diseases requires the pathogen antibioticograms.


Assuntos
Antibacterianos/farmacologia , Azitromicina/farmacologia , Infecções Comunitárias Adquiridas/microbiologia , Haemophilus influenzae/efeitos dos fármacos , Pneumonia Bacteriana/microbiologia , Staphylococcus/efeitos dos fármacos , Streptococcus/efeitos dos fármacos , Adulto , Idoso , Idoso de 80 Anos ou mais , Meios de Cultura , Feminino , Haemophilus influenzae/isolamento & purificação , Humanos , Masculino , Testes de Sensibilidade Microbiana , Pessoa de Meia-Idade , Staphylococcus/isolamento & purificação , Streptococcus/isolamento & purificação
3.
Acta Naturae ; 3(1): 99-106, 2011 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-22649678

RESUMO

Engineered nanoparticles (ENPs) are now being used in many sectors of industry; however, the impact of ENPs on the environment still requires further study, since their use, recycling, and accidental spill can result in the accumulation of nanoparticles in the atmosphere, soil, and water. Plants are an integral part of ecosystems; hence their interaction with ENPs is inevitable. It is important to understand the consequences of this interaction and assess its potential effects. The present research is focused on studying the effects of the industrial material Taunit, containing multi-walled carbon nanotubes (MWNTs), on plants, and testing of its ability to penetrate into plant cells and tissues. Taunit has been found to stimulate the growth of roots and stems and cause an increase in peroxidase activity inOnobrychis arenariaseedlings. Peroxidase activity increases with decreasing concentration of Taunit from 1,000 to 100 mg/l. MWNTs from Taunit were detected in the cells and tissues of seedling roots and leaves, implying the ability of MWNTs to penetrate into roots and accumulate there, as well as their ability to be transported into seedling leaves. Thus, the changes in the physiological parameters of plants are associated not only with MWNT adsorption on the root surface, as previously believed, but also with their penetration, uptake and accumulation in the plant cells and tissues.

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