Detalhe da pesquisa
1.
Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds.
Cell
; 160(1-2): 339-50, 2015 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25533786
2.
Biological phosphoryl-transfer reactions: understanding mechanism and catalysis.
Annu Rev Biochem
; 80: 669-702, 2011.
Artigo
Inglês
| MEDLINE | ID: mdl-21513457
3.
A kinetic mechanism for systems-level behavior in GTPase signaling.
Trends Biochem Sci
; 47(6): 459-460, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35190221
4.
CRISPR-Cas tools for simultaneous transcription & translation control in bacteria.
Nucleic Acids Res
; 52(9): 5406-5419, 2024 May 22.
Artigo
Inglês
| MEDLINE | ID: mdl-38613390
5.
Engineering activatable promoters for scalable and multi-input CRISPRa/i circuits.
Proc Natl Acad Sci U S A
; 120(30): e2220358120, 2023 07 25.
Artigo
Inglês
| MEDLINE | ID: mdl-37463216
6.
Portable bacterial CRISPR transcriptional activation enables metabolic engineering in Pseudomonas putida.
Metab Eng
; 66: 283-295, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33930546
7.
The Relationship between Effective Molarity and Affinity Governs Rate Enhancements in Tethered Kinase-Substrate Reactions.
Biochemistry
; 59(23): 2182-2193, 2020 06 16.
Artigo
Inglês
| MEDLINE | ID: mdl-32433869
8.
CRISPR-Cas-Mediated Chemical Control of Transcriptional Dynamics in Yeast.
Chembiochem
; 20(12): 1519-1523, 2019 06 14.
Artigo
Inglês
| MEDLINE | ID: mdl-30710419
9.
Prospects for engineering dynamic CRISPR-Cas transcriptional circuits to improve bioproduction.
J Ind Microbiol Biotechnol
; 45(7): 481-490, 2018 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-29740742
10.
Probing the origins of catalytic discrimination between phosphate and sulfate monoester hydrolysis: comparative analysis of alkaline phosphatase and protein tyrosine phosphatases.
Biochemistry
; 53(43): 6811-9, 2014 Nov 04.
Artigo
Inglês
| MEDLINE | ID: mdl-25299936
11.
Engineering bacteria for cancer immunotherapy.
Curr Opin Biotechnol
; 85: 103061, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38219524
12.
The Axin scaffold protects the kinase GSK3ß from cross-pathway inhibition.
Elife
; 122023 08 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37548359
13.
Multi-layer CRISPRa/i circuits for dynamic genetic programs in cell-free and bacterial systems.
Cell Syst
; 13(3): 215-229.e8, 2022 03 16.
Artigo
Inglês
| MEDLINE | ID: mdl-34800362
14.
Expanding the Scope of Bacterial CRISPR Activation with PAM-Flexible dCas9 Variants.
ACS Synth Biol
; 11(12): 4103-4112, 2022 12 16.
Artigo
Inglês
| MEDLINE | ID: mdl-36378874
15.
CRISPR-Cas-Mediated Tethering Recruits the Yeast HMR Mating-Type Locus to the Nuclear Periphery but Fails to Silence Gene Expression.
ACS Synth Biol
; 10(11): 2870-2877, 2021 11 19.
Artigo
Inglês
| MEDLINE | ID: mdl-34723510
16.
The Scaffold Protein Axin Promotes Signaling Specificity within the Wnt Pathway by Suppressing Competing Kinase Reactions.
Cell Syst
; 10(6): 515-525.e5, 2020 06 24.
Artigo
Inglês
| MEDLINE | ID: mdl-32553184
17.
Challenges and opportunities with CRISPR activation in bacteria for data-driven metabolic engineering.
Curr Opin Biotechnol
; 64: 190-198, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32599515
18.
Conditional Recruitment to a DNA-Bound CRISPR-Cas Complex Using a Colocalization-Dependent Protein Switch.
ACS Synth Biol
; 9(9): 2316-2323, 2020 09 18.
Artigo
Inglês
| MEDLINE | ID: mdl-32816470
19.
Effective CRISPRa-mediated control of gene expression in bacteria must overcome strict target site requirements.
Nat Commun
; 11(1): 1618, 2020 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32238808
20.
Arginine coordination in enzymatic phosphoryl transfer: evaluation of the effect of Arg166 mutations in Escherichia coli alkaline phosphatase.
Biochemistry
; 47(29): 7663-72, 2008 Jul 22.
Artigo
Inglês
| MEDLINE | ID: mdl-18627128