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1.
Ann Otol Rhinol Laryngol ; 121(1): 44-50, 2012 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-22312927

RESUMO

OBJECTIVES: Airway management in infants with Robin sequence (RS) remains controversial, ranging from conservative to operative methods. In some centers, tracheostomy remains the mainstay for those infants with severe respiratory obstruction. The goals of this retrospective case cohort study were to determine the length of time to decannulation without further surgical intervention (ie, "natural" decannulation) in patients with severe RS who underwent tracheostomy and to investigate potential factors associated with successful decannulation. METHODS: We reviewed all infants with RS treated at a large tertiary center from 1994 to 2010. Patients who had undergone tracheostomy were identified. Baseline demographics, complications, deaths, and time to "natural" decannulation were recorded. Statistical analysis was performed with univariate analysis and Kaplan-Meier log-rank tests. RESULTS: Of 61 infants with RS with obstructive events, 25 infants (14 with isolated RS and 11 with syndromic RS) required tracheostomy. At a mean follow-up of 4 years, the rate of tracheostomy-specific complications was 52%; the tracheostomy-specific mortality rate was 12%. Overall, 13 of 25 infants (52%) were "naturally" decannulated, with a median time to decannulation of 97 months. Patients with syndromic RS had a significantly longer median time to decannulation than did those with isolated RS (more than 73 months versus 19 months, respectively; p = 0.019). In addition, patients with long-term tracheostomy dependence had significantly higher maximum carbon dioxide levels before tracheostomy than did patients who were successfully decannulated (82.4 versus 63.2 mEq/L, respectively; p = 0.02). CONCLUSIONS: Tracheostomy in infants with RS is associated with inordinately high rates of mortality, morbidity, and long-term tracheostomy dependence, particularly in patients with syndromic RS and in those with high maximum carbon dioxide levels before tracheostomy.


Assuntos
Obstrução das Vias Respiratórias/etiologia , Obstrução das Vias Respiratórias/cirurgia , Síndrome de Pierre Robin/complicações , Traqueostomia/métodos , Estudos de Coortes , Feminino , Humanos , Lactente , Masculino , Estudos Retrospectivos
2.
Pediatr Clin North Am ; 69(2): 301-317, 2022 04.
Artigo em Inglês | MEDLINE | ID: mdl-35337541

RESUMO

Stridor is a high-pitched extrathoracic noise associated with turbulent airflow, commonly associated with respiratory distress in infants. Workup for stridor requires evaluation of the upper-respiratory airway, with severe distress requiring evaluation under anesthesia. The differential diagnosis of stridor depends on location of the obstruction, age of the patient, and acuity of the symptoms. The most common reason is laryngomalacia; most patients can be managed conservatively with resolution of symptoms by 2 years of age. In children who do not improve or have severe disease, supraglottoplasty is the treatment of choice, and the majority will have resolution of stridor postoperatively.


Assuntos
Anestesia , Laringomalácia , Laringe , Criança , Humanos , Lactente , Laringomalácia/complicações , Laringomalácia/diagnóstico , Laringomalácia/cirurgia , Sons Respiratórios/diagnóstico , Sons Respiratórios/etiologia
3.
Laryngoscope ; 131(9): 2141-2147, 2021 09.
Artigo em Inglês | MEDLINE | ID: mdl-33635575

RESUMO

OBJECTIVES/HYPOTHESIS: To identify any potential barriers for decannulation in children undergoing double-staged laryngotracheal reconstruction (dsLTR) beyond the severity of disease itself. STUDY DESIGN: Case series with chart review. METHODS: We performed a retrospective chart review from 2008 to 2018 of 41 children who had undergone dsLTR as primary treatment for laryngotracheal stenosis at a stand-alone tertiary children's hospital. We examined the effect of demographic, medical, and surgical factors on successful decannulation and time to decannulation after dsLTR. RESULTS: Of the 41 children meeting inclusion criteria who underwent dsLTR, 34 (82%) were decannulated. Age, gender, race, insurance status, medical comorbidity, and multilevel stenosis did not predict overall decannulation. Insurance status did not impact time to decannulation (P = .13, Log-rank). Factors that increased length of time to decannulation were the use of anterior and posterior cartilage grafts (P = .001, Log-rank), history of pulmonary disease (P = .05, Log rank), history of cardiac disease (P = .017, Log-rank), and race/ethnicity (P = .001 Log-rank). CONCLUSION: In a cohort with a similar decannulation rates to previous dsLTR cohorts, we identified no demographic or medical factors that influenced overall decannulation. We did observe that pulmonary comorbidity, cardiac comorbidity, and race/ethnicity lengthens time to decannulation. LEVEL OF EVIDENCE: 4 Laryngoscope, 131:2141-2147, 2021.


Assuntos
Cateterismo/estatística & dados numéricos , Laringoestenose/cirurgia , Procedimentos de Cirurgia Plástica/classificação , Estenose Traqueal/cirurgia , Adolescente , Adulto , Cartilagem/transplante , Cateterismo/tendências , Comorbidade , Feminino , Humanos , Laringoestenose/diagnóstico , Laringe/patologia , Masculino , Pessoa de Meia-Idade , Procedimentos de Cirurgia Plástica/métodos , Procedimentos de Cirurgia Plástica/estatística & dados numéricos , Estudos Retrospectivos , Índice de Gravidade de Doença , Fatores de Tempo , Traqueia/patologia , Estenose Traqueal/diagnóstico , Transplantes/estatística & dados numéricos , Transplantes/transplante , Adulto Jovem
4.
Int J Pediatr Otorhinolaryngol ; 141: 110565, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33341719

RESUMO

OBJECTIVES: To provide recommendations to otolaryngologists, pulmonologists, and allied clinicians for tracheostomy decannulation in pediatric patients. METHODS: An iterative questionnaire was used to establish expert recommendations by the members of the International Pediatric Otolaryngology Group. RESULTS: Twenty-six members completed the survey. Recommendations address patient criteria for decannulation readiness, airway evaluation prior to decannulation, decannulation protocol, and follow-up after both successful and failed decannulation. CONCLUSION: Tracheostomy decannulation recommendations are aimed at improving patient-centered care, quality and safety in children with tracheostomies.


Assuntos
Otolaringologia , Traqueostomia , Criança , Remoção de Dispositivo , Humanos , Lactente , Assistência Centrada no Paciente , Estudos Retrospectivos
5.
Int J Pediatr Otorhinolaryngol ; 129: 109770, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31733596

RESUMO

INTRODUCTION: Advanced practice providers (APPs), including nurse practitioners and physician assistants, have been deployed in children's hospital-based academic pediatric otolaryngology practices for many years. However, this relationship in terms of prevalence, roles, financial consequences and satisfaction has not been examined. The objective of this study is to explore how APPs impact healthcare delivery in this setting. METHODS: Pediatric otolaryngology chiefs of all academic children's hospitals in the US were electronically surveyed about the ways APPs intersected clinically and financially in their respective practice. RESULTS: A total of 29 of 36 children's hospital-based pediatric otolaryngology practices completed the survey, of which 26 practices (90%) utilized APP. There were large variances within the APP practice cohort in faculty size (mean/median/range = 9.4/8.5/3-29); annual patient visits (mean/median = 18,373/17,600); number of practice site (mean/median/range = 4.3/4/2-9) and number of outpatient APP (mean/median/range = 6.3/5/1-30). No factors (faculty size, annual visits and number of practice sites) differentiated between the APP and non-APP practices. Among APP practices, significant correlation (p<.00001) was observed between size of APP cohort to faculty size and annual visits. 69% of the practices did not differentiate job functions of nurse practitioners and physician assistants. 85% of the practices utilized APPs in all practice sites and 19% utilized APPs in the operating room. 77% of APPs billed independently and 46% had on-site supervision. The most prevalent APP salary bracket based on 0-5, 6-10 and > 11 years of tenure were $76-100K (65%), $100-150K (77%) and $100-150K (86%), respectively. In 46% of the practices, APPs were able to generate enough revenue to cover more than 75% of their salary and 23% of practices generated a profit. 81% of the chiefs ranked the effectiveness of APPs as high (4 and 5) on a 5-point Likert scale. DISCUSSION: The majority of academic pediatric otolaryngology practices employed APPs. Despite the diversity seen in practice complexity, APP functionality and financial impact, most found the APP model to be beneficial in improving patient care, patient access and faculty productivity.


Assuntos
Profissionais de Enfermagem/estatística & dados numéricos , Otolaringologia/organização & administração , Otolaringologia/estatística & dados numéricos , Assistentes Médicos/estatística & dados numéricos , Papel Profissional , Docentes de Medicina/estatística & dados numéricos , Hospitais Pediátricos , Humanos , Renda/estatística & dados numéricos , Profissionais de Enfermagem/organização & administração , Otolaringologia/economia , Otolaringologia/educação , Assistentes Médicos/organização & administração , Inquéritos e Questionários
6.
Otolaryngol Head Neck Surg ; 140(6): 907-11, 2009 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-19467413

RESUMO

OBJECTIVE: Controversies remain regarding the management of orbital cellulitis (OC). The objective of this study was to examine the outcomes of patients admitted to our institution for orbital cellulitis during a 7-year period. STUDY DESIGN: Case series with chart review. SETTING: Tertiary referral pediatric hospital. SUBJECTS AND METHODS: Charts of 465 consecutive OC admissions were reviewed for presentation, imaging, medical and surgical treatment, and outcome. RESULTS: Of these patients, 189 were treated in the emergency room and 276 were admitted. CT scan was performed on 240 patients. Subperiosteal abscess (SPA) was noted in 68 patients. Of these, 47 were treated medically and 21 had surgery. Surgical patients were older (8.3 vs 6.2 years, P = 0.039), had larger abscesses (>10 mm, P < 0.001), required a longer admission (10.2 vs 6.6 days, P < 0.001), and had higher temperatures on admission (38.0 degrees C vs 37.3 degrees C, P = 0.03). CONCLUSION: The majority of small SPAs as diagnosed on CT scans in younger children can be successfully treated medically. Surgery, however, should be considered for a worsening clinical examination. Our findings confirm those of previous reports on this clinical entity.


Assuntos
Abscesso/terapia , Celulite Orbitária/terapia , Periósteo , Abscesso/diagnóstico por imagem , Antibacterianos/uso terapêutico , Distribuição de Qui-Quadrado , Criança , Endoscopia , Feminino , Humanos , Masculino , Celulite Orbitária/diagnóstico por imagem , Estudos Retrospectivos , Tomografia Computadorizada por Raios X , Resultado do Tratamento
7.
Ann Otol Rhinol Laryngol ; 118(8): 592-7, 2009 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-19746759

RESUMO

OBJECTIVES: We describe our series in the surgical treatment of laryngomalacia using a microdebrider. METHODS: We performed a retrospective review of patients who underwent microdebrider-assisted supraglottoplasty for laryngomalacia between October 2004 and February 2008. Patients with neurologic conditions and secondary airway lesions were excluded. The main outcome measures included complications, pain, resolution of stridor, presence of aspiration, and need for revision surgery. RESULTS: Twenty-eight patients underwent microdebrider-assisted supraglottoplasty. The mean age at diagnosis was 109 days, and the mean age at the time of the procedure was 182 days. Nineteen patients (68%) had gastroesophageal reflux at diagnosis. The average operative time was 35.7 minutes (range, 11 to 65 minutes). No intraoperative complications or device problems occurred. Two patients remained intubated after the procedure. One patient required a tracheotomy, and 1 patient underwent revision supraglottoplasty. Three patients had aspiration that resolved. There was negligible pain from the procedure, as all patients immediately resumed a diet. All patients had immediate or eventual resolution of stridor. CONCLUSIONS: This is the largest series of patients who underwent microdebrider-assisted supraglottoplasty for laryngomalacia. This procedure is relatively safe, with minimal pain, and effective in patients with laryngomalacia. Microdebrider-assisted supraglottoplasty is the method of choice for supraglottoplasty in our institution.


Assuntos
Desbridamento/métodos , Endoscopia , Laringomalácia/patologia , Laringomalácia/cirurgia , Microcirurgia/instrumentação , Pré-Escolar , Estudos de Coortes , Feminino , Glote/cirurgia , Humanos , Lactente , Recém-Nascido , Mucosa Laríngea/cirurgia , Masculino , Estudos Retrospectivos , Resultado do Tratamento
8.
Ann Otol Rhinol Laryngol ; 118(7): 495-9, 2009 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-19708488

RESUMO

OBJECTIVES: We performed a retrospective review to determine the utility of bronchoscopy in patients with recurrent croup (RC). METHODS: Bronchoscopy was performed on 30 patients with a diagnosis of RC (age, 14 months to 13.9 years) over a 2-year period. RESULTS: One third of the patients (33.3%) were found to have airway disorders, including subglottic stenosis (7), subglottic edema (2), and a subglottic cyst (1). Patients with RC who were less than 3 years of age were more likely to have an airway abnormality found on endoscopy (9 of 14 or 64.2%) than were those older than 3 years (1 of 16 or 6.2%; chi2 p < 0.001). There was no statistically significant difference in abnormal findings 1) in patients with RC who had a history of prematurity or prior intubations (chi2, p = 0.17 and p = 0.052, respectively); 2) between infectious and spasmodic croup (chi2, p = 0.794); or 3) by number of croup episodes (chi2, p = 0.300). Two patients required surgical intervention (laryngotracheal reconstruction and marsupialization of a subglottic cyst). CONCLUSIONS: Of 30 patients who underwent bronchoscopy for RC, 33% had airway disorders--mostly children less than 3 years old. We suggest a higher index of suspicion for finding airway disorders in children less than 3 years old with RC and having a lower threshold for performing diagnostic bronchoscopy in this population.


Assuntos
Broncoscopia , Crupe/diagnóstico , Crupe/terapia , Adolescente , Fatores Etários , Criança , Pré-Escolar , Estudos de Coortes , Crupe/etiologia , Feminino , Humanos , Lactente , Masculino , Valor Preditivo dos Testes , Recidiva , Estudos Retrospectivos , Fatores de Risco
9.
Int J Pediatr Otorhinolaryngol ; 73(1): 119-25, 2009 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-19062109

RESUMO

With the introduction of vaccination for haemophilus influenza, the epidemiology of epiglottitis in children has changed. Classic childhood epiglottitis is now rare, and unusual forms of the disease may be seen. Nectrotizing epiglottitis is an extremely rare form of epiglottitis. Only four cases of nectrotizing epiglottitis have been previously reported, and all cases were in immunocompromised adult patients. Hemophagocytic lymphohistiocytosis is a rare condition characterized by high fevers, hepatosplenomegaly, and cytopenias caused by an abnormal proliferation and activation of macrophages. We report the first case of a previously healthy 5-year-old male presenting with acute onset of airway distress and pancytopenia. Subsequent airway evaluation led to the diagnosis of nectrotizing epiglottitis, and he was simultaneously diagnosed with infection-induced hemophagocytic lymphohistiocytosis. The patient recovered with intubation and antibiotics. Follow-up direct laryngoscopy revealed an epiglottis remnant with approximately 50% loss of epiglottic tissue. The presentation and pathophysiology of this unusual manifestation of epiglottitis and hemophagocytic lymphohistiocytosis will be reviewed. In the post-haemophilus influenze vaccination era, the pediatric otolaryngologist must be familiar with unusual forms of epiglottitis and its associated manifestations.


Assuntos
Epiglotite/etiologia , Epiglotite/patologia , Linfo-Histiocitose Hemofagocítica/complicações , Linfo-Histiocitose Hemofagocítica/diagnóstico , Infecções Bacterianas/complicações , Pré-Escolar , Epiglotite/terapia , Humanos , Linfo-Histiocitose Hemofagocítica/microbiologia , Masculino , Necrose/diagnóstico , Necrose/etiologia , Necrose/terapia
10.
Otolaryngol Head Neck Surg ; 138(2): 233-41, 2008 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-18241722

RESUMO

OBJECTIVE: The purpose of this study was to determine resource utilization in managing subglottic stenosis. STUDY DESIGN: The Kids' Inpatient Database (KID) 2003 was analyzed. SUBJECTS AND METHODS: International Classification of Diseases, Ninth Revision code 478.74 was the inclusion criteria. RESULTS: Two thousand forty-six admissions with subglottic stenosis were sampled; there were 10 deaths (0.49%). States with the most admissions were Ohio, California, and Illinois; these did not have the highest spending per admission. Two hundred eighteen (10.7%) underwent a laryngeal graft procedure; states with the most were Ohio (35.8%), Texas, California, and Florida. Indicators of increased resource utilization include length of stay, nonelective admission, race, primary payer, hospital location, and type. CONCLUSIONS: For subglottic stenosis, three states account for 37% of admissions, and four states account for 56% of laryngeal graft procedures in 2003. The mean total charges were $53,787; 90% of admissions had total charges less than $139,253. Patients who underwent surgical procedures had total charges of $76,409.


Assuntos
Recursos em Saúde/estatística & dados numéricos , Preços Hospitalares/estatística & dados numéricos , Hospitalização/economia , Laringoestenose/cirurgia , Procedimentos Cirúrgicos Otorrinolaringológicos/métodos , Implantação de Prótese/economia , Pré-Escolar , Feminino , Glote , Hospitalização/tendências , Humanos , Laringoestenose/mortalidade , Masculino , Procedimentos Cirúrgicos Otorrinolaringológicos/economia , Implantação de Prótese/métodos , Taxa de Sobrevida , Estados Unidos/epidemiologia
11.
Ann Otol Rhinol Laryngol ; 116(5): 389-97, 2007 May.
Artigo em Inglês | MEDLINE | ID: mdl-17561770

RESUMO

OBJECTIVES: The purpose of this study was to analyze the secretory cell population and distribution of MUC5B and MUC7 mucins in the sinus mucosa of pediatric patients with and without chronic rhinosinusitis (CRS). METHODS: Sinus mucosal specimens were collected at surgery in a pediatric tertiary care facility. Histologic, immunohistochemical, and morphometric analyses were performed on sinus mucosa of 20 children with CRS and 7 children without CRS. RESULTS: A significant increase in the area of submucosal glands was evident in the sinus mucosa of children with CRS as compared to controls. MUC5B and MUC7 mucins were expressed in the submucosal glands, as well as in goblet cells, in the sinus mucosa of both populations. No differences in MUC5B or MUC7 expression were observed when mucin expression was normalized to glandular area. CONCLUSIONS: Children with CRS have an increased number of submucosal glands, indicating that glandular mucins contribute to mucus overproduction in CRS. MUC5B and MUC7 mucins, which have previously been considered only glandular mucins, are also expressed in goblet cells in the sinus mucosa.


Assuntos
Mucinas/metabolismo , Mucosa Nasal/metabolismo , Adolescente , Estudos de Casos e Controles , Criança , Pré-Escolar , Doença Crônica , Epitélio/metabolismo , Feminino , Células Caliciformes/metabolismo , Humanos , Imuno-Histoquímica , Masculino , Rinite/metabolismo , Sinusite/metabolismo
12.
Int J Pediatr Otorhinolaryngol ; 101: 51-56, 2017 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-28964310

RESUMO

INTRODUCTION: The diagnosis and management of type I laryngeal clefts can be controversial and varies across centers and surgeons. Using existing peer-reviewed literature to develop an expert-based consensus will help guide physicians in the treatment of these patients as well as develop research hypotheses to further study this condition. OBJECTIVE: To provide recommendations for the diagnosis and management of type I laryngeal clefts. METHODS: Determination of current expert- and literature-based recommendations, via a survey of the International Pediatric Otolaryngology Group, using a modified Delphi method. SETTING: Multinational, multi-institutional, tertiary pediatric hospitals. RESULTS: Consensus recommendations include diagnostic workup, medical management, pre-operative, intra-operative and post-operative considerations for type I laryngeal clefts. CONCLUSIONS: This guide on the diagnosis and management of patients with type I laryngeal clefts is aimed at improving patient care and promoting future hypothesis generation and research to validate the recommendations made here.


Assuntos
Anormalidades Congênitas/diagnóstico , Laringe/anormalidades , Otolaringologia/métodos , Criança , Anormalidades Congênitas/cirurgia , Consenso , Guias como Assunto , Humanos , Laringe/cirurgia , Médicos , Inquéritos e Questionários
13.
Otolaryngol Head Neck Surg ; 134(5): 852-5, 2006 May.
Artigo em Inglês | MEDLINE | ID: mdl-16647547

RESUMO

OBJECTIVES: To compare postoperative complication rates of coblation and electrocautery adenotonsillectomies. STUDY DESIGN: Retrospective chart review. RESULTS: From January 2000 to June 2004, 1997 pediatric patients underwent adenotonsillectomy. 745 coblation, and 1252 electrocautery tonsillectomies were performed. Primary bleed, secondary bleed, and dehydration were seen in 3, 35, and 23 coblation, and 9, 41, and 64 electrocautery tonsillectomies, respectively. Data analysis revealed no significant difference in primary and secondary hemorrhage rate, but a higher dehydration rate in the electrocautery group (P=0.0423). A total of 602 coblation, 763 curette/cautery, and 632 electrocautery adenoidectomies were performed. Neck pain was seen in 0, 17, and 3 patients, respectively. Data analysis showed a higher incidence of neck pain with the curette/cautery technique compared with coblator and cautery techniques (P=0.0006 and P=0.0119, respectively). CONCLUSIONS: Coblation tonsillectomy had similar rates of primary and secondary hemorrhage when compared with electrocautery tonsillectomy but a lower incidence of postoperative dehydration. Coblation adenoidectomy caused less postoperative neck pain than curette/cautery adenoidectomy without significant advantage over cautery adenoidectomy. EBM RATING: B-3b.


Assuntos
Adenoidectomia/métodos , Tonsila Faríngea/cirurgia , Eletrocoagulação/tendências , Tonsilectomia/métodos , Tonsilite/cirurgia , Adenoidectomia/tendências , Adolescente , Criança , Pré-Escolar , Doença Crônica , Seguimentos , Humanos , Incidência , Lactente , Hemorragia Pós-Operatória/epidemiologia , Estudos Retrospectivos , Tonsilectomia/tendências , Tonsilite/complicações , Resultado do Tratamento
14.
Ann Otol Rhinol Laryngol ; 115(6): 477-81, 2006 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-16805381

RESUMO

OBJECTIVES: This pilot study evaluated the role of cartilage-derived morphogenic proteins (CDMPs) as promoters of cartilage growth and differentiation and as a possible alternative to autologous cartilage grafts in laryngotracheal reconstruction. METHODS: In phase 1, 6 New Zealand rabbits underwent subperichondrial injection of CDMP-1, CDMP-2, or CDMP-3 in the right thyroid ala and normal saline solution in the left thyroid ala as controls. In phase 2, 14 rabbits underwent anterior cricoid split and interposition of a fibrillar collagen sponge saturated with normal saline solution, CDMP-2, or CDMP-3. RESULTS: In both phases, saline solution failed to induce new cartilage or bone growth. Small foci of cartilage and/or bone formation were observed within the thyroid subperichondria of those rabbits injected with CDMP-2 or CDMP-3. In phase 2, a few small foci of new cartilage and/or bone formation were observed at the edges of the cricoid split with CDMP-2 and CDMP-3. CONCLUSIONS: A different carrier of CDMP, a change in dosage, or a combination of CDMPs might yield more significant neochondrification. The role of CDMPs as promoters of cartilage and differentiation could not be disqualified in this study and should be further investigated.


Assuntos
Proteínas Morfogenéticas Ósseas/uso terapêutico , Laringoestenose/tratamento farmacológico , Estenose Traqueal/tratamento farmacológico , Animais , Proteínas Morfogenéticas Ósseas/administração & dosagem , Modelos Animais de Doenças , Seguimentos , Fator 5 de Diferenciação de Crescimento , Injeções , Cartilagens Laríngeas , Laringoestenose/complicações , Laringoestenose/patologia , Projetos Piloto , Coelhos , Estenose Traqueal/complicações , Estenose Traqueal/patologia , Fator de Crescimento Transformador beta/administração & dosagem , Fator de Crescimento Transformador beta/uso terapêutico , Resultado do Tratamento
15.
Ear Nose Throat J ; 95(3): 108-12, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26991219

RESUMO

Otogenic lateral sinus thrombosis (LST) is a rare but serious intracranial complication of acute or chronic otitis media. Reported mortality rates have ranged from 8 to 25%; the pediatric mortality rate might be as low as 5%. Controversy still exists over the medical and surgical management of this condition. We conducted a retrospective chart review of 7 cases of pediatric otogenic LST that were treated at our institution over a period of 8 years. We hypothesized that good outcomes in very sick patients can be achieved by aggressively managing the mastoid cavity and without the need for a thrombectomy. Our study group was made up of 4 boys and 3 girls, aged 6 to 15 years (mean: 11.1). All patients received intravenous antibiotics and underwent mastoidectomy with unroofing of the sigmoid sinus and placement of a tympanostomy tube. Sinus exploration with thrombectomy was not performed in any patient. Anticoagulation was used perioperatively in 5 patients (71%) without complication. All patients recovered well without major sequelae, which supports our hypothesis. We also describe the case of a patient with multiple concomitant intracranial comorbidities associated with this rare condition.


Assuntos
Trombose do Seio Lateral/terapia , Processo Mastoide/cirurgia , Mastoidite/complicações , Otite Média/complicações , Adolescente , Antibacterianos/uso terapêutico , Anticoagulantes/uso terapêutico , Criança , Feminino , Humanos , Trombose do Seio Lateral/etiologia , Masculino , Ventilação da Orelha Média , Estudos Retrospectivos
16.
Otolaryngol Head Neck Surg ; 132(2): 226-31, 2005 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-15692531

RESUMO

OBJECTIVE: To evaluate the success and complications of various treatment options of congenital subglottic hemangioma. STUDY DESIGN AND SETTINGS: Reported cases were grouped by treatment modalities and corresponding outcome evaluated. RESULTS: From 1986 through 2002, 372 patients were reported in 28 series. Carbon dioxide laser had 88.9% success rate yet 5.5 % significant subglottic stenosis. It shortened the tracheotomy duration by 13.7 months. Corticosteroids were not that beneficial (useful in only 24.5%) with 12.9% side effects. Intralesional corticosteroids were successful in 86.4% with 5.6% complication rate. Surgical excision (as young as 2.5 months), was useful in 98% with 10% complication rate, using cartilage grafts in 34%. Other modalities were less popular. CONCLUSION: Treatment should be individualized. Guidelines are suggested. Priority is given to secure the airways. The CO 2 laser is useful when used cautiously. Steroids may be beneficial. Excision is for stubborn cases.


Assuntos
Glote/cirurgia , Hemangioma/congênito , Hemangioma/terapia , Neoplasias Laríngeas/congênito , Neoplasias Laríngeas/terapia , Procedimentos Cirúrgicos Otorrinolaringológicos/tendências , Pré-Escolar , Feminino , Hemangioma/diagnóstico , Humanos , Lactente , Recém-Nascido , Neoplasias Laríngeas/diagnóstico , Masculino , Resultado do Tratamento
17.
Ann Otol Rhinol Laryngol ; 114(12): 958-65, 2005 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-16425564

RESUMO

OBJECTIVES: The purpose of this study was to analyze MUC5AC protein expression in sinus mucosal specimens of children with and without chronic sinusitis. METHODS: Morphometric, histologic, and immunohistochemical analyses were carried out on sinus mucosa of 7 children with chronic sinusitis and 6 children without sinusitis. RESULTS: MUC5AC protein was expressed in a subset of goblet cells in the surface epithelium, but not in the submucosal glands in either pediatric population. The number of goblet cells that expressed MUC5AC mucin was not significantly different in patients with and without chronic sinusitis. All specimens had similar numbers of goblet cells in the surface epithelium. CONCLUSIONS: The data demonstrate that neither goblet cell hyperplasia nor increased MUC5AC expression occurs in the sinus mucosa of children with chronic sinusitis. This suggests that in contrast to asthma, in which goblet cell hyperplasia is present in the lower respiratory tract, mucus hypersecretion in pediatric chronic sinusitis may involve other secretory cells, eg, submucosal glandular cells, and mucins secreted by these glandular cells.


Assuntos
Mucinas/genética , Mucinas/metabolismo , Mucosa Nasal/metabolismo , Mucosa Nasal/patologia , Sinusite/metabolismo , Contagem de Células , Criança , Pré-Escolar , Doença Crônica , Feminino , Células Caliciformes/patologia , Humanos , Hiperplasia/patologia , Imuno-Histoquímica , Masculino , Mucina-5AC , Sinusite/genética , Sinusite/patologia
18.
Int J Pediatr Otorhinolaryngol ; 69(3): 305-9, 2005 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-15733588

RESUMO

OBJECTIVE: Although laryngomalacia is a common cause for infantile stridor, few patients eventually go on to require surgical intervention. When surgery is required, the location of tissue excised may vary depending on the endoscopic findings, but only two methods of tissue excision are described-cold knife excision and carbon dioxide laser. We present our experience of using the microdebrider to excise tissue during supraglottoplasty. METHODS: Over the last 12 months, patients were identified who had undergone supraglottoplasty, and their final outcomes with regards to resolution of stridor, cor pulmonale, and/or failure to thrive were assessed. A description of the indications for supraglottoplasty and the actual technique utilizing the microdebrider is included. RESULTS: Five patients were identified as having undergone a microdebrider-assisted supraglottoplasty. All five had resolution of their stridor following surgery. No new complications such as aspiration or supraglottic stenosis were identified. No revision surgeries were required. The microdebrider was used to trim the aryepiglottic folds and/or redundant arytenoid mucosa in all cases. CONCLUSIONS: The microdebrider appears to be a safe and effective tool to remove redundant tissue during supraglottoplasty.


Assuntos
Desbridamento/instrumentação , Glote/cirurgia , Doenças da Laringe/cirurgia , Laringoscopia/métodos , Microcirurgia/instrumentação , Humanos , Laringe/anormalidades , Laringe/cirurgia , Índice de Gravidade de Doença
19.
JAMA Otolaryngol Head Neck Surg ; 141(10): 919-22, 2015 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-26356011

RESUMO

IMPORTANCE: Interest in pediatric otolaryngology fellowship training is growing. The workforce implications of this growing interest are unclear and understudied. OBJECTIVES: To analyze trends in pediatric otolaryngology training, determine where fellows who graduated over the past 10 years are currently practicing, and test the hypothesis that graduates from Accreditation Council for Graduate Medical Education (ACGME)­accredited programs were more likely to have academic tertiary positions with faculty appointments. DESIGN, SETTING, AND PARTICIPANTS: We conducted a web-based analysis of pediatric otolaryngology fellowship graduates. The names of all 274 applicants who were matched to pediatric otolaryngology fellowships from May 31, 2003, to May 31, 2014, were obtained from the SF Match website. Accreditation status of each program for each match year was obtained from the ACGME website. We then performed an Internet search for the current practice location of each matched applicant. Analysis was conducted from January 1, 2015, to May 1, 2015. MAIN OUTCOMES AND MEASURES: Practice setting per year of fellowship match and accreditation status of program. RESULTS: For the 2003 to the 2014 match years, there was an increase from 5 to 22 accredited pediatric otolaryngology fellowship programs overall; simultaneously, the number of yearly matched applicants increased from 14 to 35. More graduates with ACGME accreditation practice at academic settings compared with graduates without ACGME accreditation although the difference was not statistically significant (67.1% vs. 50.7%; P = .15). Graduates from accredited programs, however, were significantly more likely to practice at a hospital-based setting compared with those from nonaccredited programs (81.7% vs. 65.5%; P = .003). Fellows trained in the last 10 years are relatively well distributed across the country. CONCLUSIONS AND RELEVANCE: The number of pediatric otolaryngology fellowship applicants as well as total number of matched applicants and ACGME-accredited positions has risen in the last 10 years. It appears that a higher proportion of fellows trained in accredited programs work in academic positions in hospital-based practices. The long-term effect on the pediatric otolaryngology workforce of training more fellows in accredited fellowships remains to be seen.


Assuntos
Acreditação/estatística & dados numéricos , Escolha da Profissão , Educação de Pós-Graduação em Medicina/estatística & dados numéricos , Bolsas de Estudo/estatística & dados numéricos , Otolaringologia/educação , Pediatria/educação , Humanos , Estados Unidos
20.
Arch Otolaryngol Head Neck Surg ; 128(4): 425-8, 2002 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-11926919

RESUMO

OBJECTIVE: To assess the advantages of powered instrumentation vs the carbon dioxide laser in treating patients with juvenile-onset recurrent respiratory papillomatosis. DESIGN: A retrospective study. SETTING: Tertiary care children's hospital. PATIENTS: Patients operated on for juvenile-onset recurrent respiratory papillomatosis between January 1, 1999, and December 31, 2000. Papillomas were excised using the microdebrider in one group and the carbon dioxide laser in the second group. INTERVENTIONS: Direct laryngoscopy and bronchoscopy, suspension microlaryngoscopy, and excision of papillomas by the carbon dioxide laser or the microdebrider. MAIN OUTCOME MEASURES: Operative time and postoperative complications. RESULTS: Seventy-three operations were performed (23 with the laser and 50 with the microdebrider). Sixteen patients were included, 10 with active disease and 5 with disease in remission; 1 was lost to follow-up. They had a mean age of 3.75 years, and the male-female ratio was 7:9. The patients presented mostly with hoarseness (13 [81%]). Four (25%) had soft tissue complications with the laser. The microdebrider was less time-consuming than the laser, although those treated with the microdebrider had more active disease. No factor could be used to measure treatment outcome due to disease variability. Those who were older, female, and African American tended to have less severe manifestations of disease. CONCLUSIONS: The microdebrider proved to be less time-consuming than the carbon dioxide laser when used in patients with juvenile-onset recurrent respiratory papillomatosis. Soft tissue complications were nonexistent. In addition to safety, the microdebrider is more appealing to the surgeon, anesthesiologist, and parents, especially because these children often need subsequent surgical procedures.


Assuntos
Broncoscopia/métodos , Laringoscopia/métodos , Neoplasias Primárias Múltiplas/cirurgia , Papiloma/cirurgia , Neoplasias do Sistema Respiratório/cirurgia , Criança , Pré-Escolar , Desbridamento/instrumentação , Feminino , Humanos , Lactente , Neoplasias Laríngeas/cirurgia , Terapia a Laser , Masculino , Microcirurgia/instrumentação , Complicações Pós-Operatórias
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