Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 52
Filtrar
1.
J Arthroplasty ; 39(2): 427-432, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-37597819

RESUMO

BACKGROUND: Osteoporosis increases the risk of periprosthetic fracture and loosening in hip arthroplasty. Many methods have been proposed to assess bone quality in X-rays, including both qualitative such as the Dorr classification and quantitative such as the Calcar-Canal Ratio (CCR) and Cortical-Thickness index/Canal-Bone ratio (CTI/CBR). The Canal-Diaphysis ratio (CDR) has been described as a predictor for hip fragility fractures; however, its relationship with bone mineral density (BMD) has not been described. The purpose of this study was to evaluate the correlation of the Dorr classification, CCR, CTI/CBR, and CDR with BMD of the proximal femur in patients without hip fracture. METHODS: Forty-seven patients over 45 years of age who had less than 6 months between radiographs and dual-energy X-ray absorptiometry were evaluated. Measurements of CCR, CBR, CDR, and Dorr classification were performed in all radiographs by 2 independent observers. RESULTS: The CDR had a high correlation (r = 0.74, P=<0.01) with BMD, whereas the CTI/CBR had a moderate correlation (r = 0.49, P=<0.01), and the CCR had no correlation with BMD (r = 0.06, P = .96). When evaluating the receiver operating characteristic curve, CDR showed the best performance (area under curve [AUC] = 0.75) followed by CBR (AUC = 0.73) and CCR (AUC = 0.61). The optimal cutoff value for the CDR was 0.49, with 100% sensitivity and 58% specificity. The inter- and intra-observer variability was good for all methods. No differences were found between Dorr classification of patients who had or did not have osteoporosis. CONCLUSION: Of all the analyzed methods, the CDR was found to have the best correlation with BMD. This study proposes the use of CDR as a tool for assessing bone quality when deciding the implant fixation method in hip arthroplasty.


Assuntos
Fraturas do Quadril , Osteoporose , Humanos , Lactente , Diáfises , Densidade Óssea , Absorciometria de Fóton , Osteoporose/diagnóstico por imagem , Osso e Ossos , Fêmur/diagnóstico por imagem , Fêmur/cirurgia
2.
Rev Med Chil ; 150(10): 1361-1369, 2022 Oct.
Artigo em Espanhol | MEDLINE | ID: mdl-37358095

RESUMO

Musculoskeletal tumors are uncommon. However, the true burden of all bone and soft tissue tumors of extremities is underestimated. Usually, the diagnosis of sarcomas is missed or delayed. Therefore, an adequate clinical and radiological assessment, along with the awareness and application of simple guidelines for referral to a specialized center, are of utmost importance. These are critical steps for an appropriate diagnosis and treatment of sarcomas, improving their prognosis.


Assuntos
Neoplasias Ósseas , Neoplasias Musculares , Encaminhamento e Consulta , Sarcoma , Neoplasias de Tecidos Moles , Humanos , Neoplasias Ósseas/diagnóstico por imagem , Neoplasias Ósseas/terapia , Diagnóstico Tardio , Diagnóstico Ausente , Neoplasias Musculares/diagnóstico por imagem , Neoplasias Musculares/terapia , Guias de Prática Clínica como Assunto , Prognóstico , Sarcoma/diagnóstico por imagem , Sarcoma/terapia , Neoplasias de Tecidos Moles/diagnóstico por imagem , Neoplasias de Tecidos Moles/terapia , Adolescente
3.
Rev Med Chil ; 147(2): 199-205, 2019 Feb.
Artigo em Espanhol | MEDLINE | ID: mdl-31095168

RESUMO

BACKGROUND: As the population ages, patients exposed to osteoporotic fractures increase, especially hip fracture, which is the most severe and costly. AIM: To characterize surgical practices in the management of hip fractures in older patients through a nationwide survey of specialized hip surgeons dedicated to the care of these patients. MATERIAL AND METHODS: A survey composed of 32 questions was formulated, including demographic factors, preoperative evaluation, definitive treatment, and postoperative management. It was sent to 140 specialists. 84 of them replied (61%), and 71 answers were included. RESULTS: Eighty six percent of respondents agreed that orthogeriatric management is fundamental in the outcome of these patients, but only 73% had the collaboration of an internist or a geriatrician. Although 97% considered 72 hours or less the ideal time to perform surgery, only 52% of the respondents declared performing surgery within that timeframe, with differences between private and public system. Regarding surgical treatment, 94-98% of femoral neck fractures are treated with an arthroplasty and 98-99% of per-subtrochanteric fractures are treated with internal fixation and osteosynthesis. Osteoporosis treatment is only carried out by 51% of the respondents and with significant variation. CONCLUSIONS: This survey shows that there is agreement in surgical practice between specialists treating these patients, but clear differences in preoperative optimization, treatment timeframe, and post fracture medical treatment.


Assuntos
Fraturas do Quadril/cirurgia , Cirurgiões Ortopédicos/estatística & dados numéricos , Padrões de Prática Médica/estatística & dados numéricos , Inquéritos e Questionários , Idoso , Chile , Correio Eletrônico , Fraturas do Colo Femoral/cirurgia , Fixação Interna de Fraturas , Humanos , Pessoa de Meia-Idade , Osteoporose/terapia , Cuidados Pós-Operatórios/estatística & dados numéricos , Tempo para o Tratamento
4.
Clin Orthop Relat Res ; 475(9): 2176-2186, 2017 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-28205076

RESUMO

BACKGROUND: Distinguishing a benign enchondroma from a low-grade chondrosarcoma is a common diagnostic challenge for orthopaedic oncologists. Low interrater agreement has been observed for the diagnosis of cartilaginous neoplasms among radiologists and pathologists, but, to our knowledge, no study has evaluated inter- and intraobserver agreement among orthopaedic oncologists grading these lesions using initial clinical and imaging information. Determining such agreement is important since it reflects the certainty in the diagnosis by orthopaedic oncologists. Agreement also is important as it will guide future treatment and prognosis, considering that there is no gold standard for diagnosis of these lesions. QUESTIONS/PURPOSES: (1) to determine inter- and intraobserver agreement among a multinational panel of expert orthopaedic oncologists in diagnosing cartilaginous neoplasms based on their assessment of clinical symptoms and imaging at diagnosis. (2) To describe the most important clinical and imaging features that experts use during the initial diagnostic process. (3) To determine interobserver agreement for proposed initial treatment strategies for cartilaginous neoplasms by this panel of evaluators. METHODS: Thirty-nine patients with intramedullary cartilaginous neoplasms of the appendicular skeleton of various histopathologic grades were selected and classified as having benign, low-grade malignant, or intermediate- or high-grade malignant neoplasms by 10 experienced orthopaedic oncologists based on clinical and imaging information. Additionally, they chose the three most important clinical or imaging features for the diagnosis of these neoplasms, and they proposed a treatment strategy for each patient. The Kappa coefficient (κ) was used to determine inter- and intraobserver agreement. RESULTS: Inter- and intraobserver agreements were only fair to good, κ = 0.44(95% CI, 0.41-0.48) and κ = 0.62 (95% CI, 0.52-0.72), respectively. The three factors most frequently identified as helpful in making the diagnosis by our panel were cortical involvement in 65% of evaluations (253/390), neoplasm size in 51% (198/390), and pain in 50% (194/390). The interobserver agreement for the proposed initial treatment strategy after diagnosis was poor (κ = 0.21; 95% CI, 0.18-0.24). CONCLUSIONS: This study showed barely fair interobserver and fair to good intraobserver agreement for grading of intramedullary cartilaginous neoplasms by orthopaedic oncologists using initial clinical and imaging findings. These results reflect the insufficient guidance interpreting clinical and imaging features, and the limitations of the systems we use today when making these diagnoses. In the same way, they generate concern for the implications that this may have on different treatment strategies and the future prognosis of our patients. Future studies should build on these observations and focus on clarifying our criteria of diagnosis so that treatment recommendations are standardized regardless of the treating institution or oncologist. LEVEL OF EVIDENCE: Level III, diagnostic study.


Assuntos
Neoplasias Ósseas/diagnóstico , Condrossarcoma/diagnóstico , Tomada de Decisão Clínica/métodos , Oncologistas/estatística & dados numéricos , Cirurgiões Ortopédicos/estatística & dados numéricos , Adulto , Idoso , Idoso de 80 Anos ou mais , Neoplasias Ósseas/patologia , Condrossarcoma/patologia , Feminino , Humanos , Masculino , Oncologia/métodos , Oncologia/normas , Oncologia/estatística & dados numéricos , Pessoa de Meia-Idade , Gradação de Tumores , Variações Dependentes do Observador , Ortopedia/métodos , Ortopedia/normas , Ortopedia/estatística & dados numéricos , Reprodutibilidade dos Testes
5.
Eur Spine J ; 25(2): 590-5, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-25070790

RESUMO

PURPOSE: The prevalence of spondylolysis reported from radiograph-based studies has been questioned in recent computed tomography (CT)-based studies in adults; however, no new data are available in pediatric patients. Spina bifida occulta (SBO), which has been associated to spondylolysis, may be increasing its prevalence, according to recent studies in adults in the last decades, but without new data in pediatric patients. We aimed to determine the prevalence of spondylolysis and SBO in pediatric patients using abdomen and pelvis CT as a screening tool. METHODS: We studied 228 patients 4-15 years old (107 males), who were evaluated with abdomen and pelvis CT scans for reasons not related to the spine. The entire lumbo-sacral spine was evaluated to detect the presence of spondylolysis and SBO. We compared the prevalence of spondylolysis in patients with and without SBO. A logistic regression analysis was performed to determine the effect of age and sex as independent predictors of spondylolysis and SBO. RESULTS: The prevalence of spondylolysis was 3.5 % (1.1-5.9 %); 2/8 patients presented with olisthesis, both with grade I slip. The prevalence of SBO was 41.2 % (34.8-59.2 %) (94 patients). Spondylolysis was not more frequent in patients with SBO than in patients without SBO. Male sex and decreasing age independently predicted the presence of SBO, but not of spondylolysis. CONCLUSION: We observed a 3.5 % prevalence of spondylolysis and a 41.2 % prevalence of SBO. SBO was significantly more frequent in males and younger patients.


Assuntos
Espinha Bífida Oculta/epidemiologia , Espondilólise/epidemiologia , Adolescente , Fatores Etários , Criança , Pré-Escolar , Estudos Transversais , Feminino , Humanos , Modelos Logísticos , Vértebras Lombares/diagnóstico por imagem , Masculino , Programas de Rastreamento , Prevalência , Fatores Sexuais , Espinha Bífida Oculta/diagnóstico , Espinha Bífida Oculta/diagnóstico por imagem , Espondilólise/diagnóstico , Espondilólise/diagnóstico por imagem , Tomografia Computadorizada por Raios X
6.
Eur Spine J ; 25(2): 596-601, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26153679

RESUMO

PURPOSE: Several studies using magnetic resonance imaging (MRI) to evaluate the lumbar spine in adults have shown a large prevalence of degenerative changes in asymptomatic subjects; however, studies in pediatric patients are scarce. Those studies have suggested a lower rate of degenerative findings in adolescents than in adults, but the actual prevalence of MRI findings in the pediatric population has not yet been determined. We aimed to determine the prevalence of degenerative changes in the lumbar spine of pediatric patients using abdominal and pelvic MRI as the screening tool. METHODS: We studied 103 patients (mean age 6.6 years) who were evaluated with abdominal and pelvic MRI for indications that were not spine related. The entire lumbo-sacral spine was evaluated to detect the presence of disc degeneration (DD), disc displacement, anular rupture with high-intensity zone (HIZ) and Modic changes. RESULTS: In our population, 10.7 % [4.9-16.5] had at least one disc classified as Pfirrmann 2, and no patients presented discs classified as Pfirrmann 3, 4 or 5; patients exhibiting discs classified as Pfirrmann 2 were significantly older than patients who had only Pfirrmann 1 discs. The prevalence of disc bulging was 1 % [0-2.9]. No patients presented disc herniation (including protrusion or extrusions); additionally, no patients exhibited HIZ or Modic changes. CONCLUSIONS: Incidental findings related to DD are very uncommon at this early age, in contrast to findings described in adults or later in adolescence.


Assuntos
Achados Incidentais , Degeneração do Disco Intervertebral/epidemiologia , Deslocamento do Disco Intervertebral/epidemiologia , Disco Intervertebral/patologia , Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Degeneração do Disco Intervertebral/diagnóstico , Degeneração do Disco Intervertebral/patologia , Deslocamento do Disco Intervertebral/diagnóstico , Deslocamento do Disco Intervertebral/patologia , Vértebras Lombares , Imageamento por Ressonância Magnética , Masculino , Programas de Rastreamento , Prevalência
7.
Eur Spine J ; 25(7): 2185-92, 2016 07.
Artigo em Inglês | MEDLINE | ID: mdl-26945747

RESUMO

PURPOSE: We performed an agreement study using two subaxial cervical spine classification systems: the AOSpine and the Allen and Ferguson (A&F) classifications. We sought to determine which scheme allows better agreement by different evaluators and by the same evaluator on different occasions. METHODS: Complete imaging studies of 65 patients with subaxial cervical spine injuries were classified by six evaluators (three spine sub-specialists and three senior orthopaedic surgery residents) using the AOSpine subaxial cervical spine classification system and the A&F scheme. The cases were displayed in a random sequence after a 6-week interval for repeat evaluation. The Kappa coefficient (κ) was used to determine inter- and intra-observer agreement. RESULTS: Inter-observer: considering the main AO injury types, the agreement was substantial for the AOSpine classification [κ = 0.61 (0.57-0.64)]; using AO sub-types, the agreement was moderate [κ = 0.57 (0.54-0.60)]. For the A&F classification, the agreement [κ = 0.46 (0.42-0.49)] was significantly lower than using the AOSpine scheme. Intra-observer: the agreement was substantial considering injury types [κ = 0.68 (0.62-0.74)] and considering sub-types [κ = 0.62 (0.57-0.66)]. Using the A&F classification, the agreement was also substantial [κ = 0.66 (0.61-0.71)]. No significant differences were observed between spine surgeons and orthopaedic residents in the overall inter- and intra-observer agreement, or in the inter- and intra-observer agreement of specific type of injuries. CONCLUSION: The AOSpine classification (using the four main injury types or at the sub-types level) allows a significantly better agreement than the A&F classification. The A&F scheme does not allow reliable communication between medical professionals.


Assuntos
Vértebras Cervicais/lesões , Fraturas da Coluna Vertebral/classificação , Vértebras Cervicais/diagnóstico por imagem , Humanos , Imageamento por Ressonância Magnética , Lesões do Pescoço/classificação , Lesões do Pescoço/diagnóstico por imagem , Variações Dependentes do Observador , Cirurgiões Ortopédicos , Radiografia , Reprodutibilidade dos Testes , Fraturas da Coluna Vertebral/diagnóstico por imagem , Traumatismos da Coluna Vertebral/classificação , Traumatismos da Coluna Vertebral/diagnóstico por imagem , Tomografia Computadorizada por Raios X
8.
J Spinal Disord Tech ; 28(7): E417-21, 2015 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-24589499

RESUMO

STUDY DESIGN: Retrospective study. OBJECTIVE: To study the clinical outcomes of patients suffering from pyogenic spinal infections (PSI), by comparing the outcomes of patients with an identified microbiological agent with those of patients without an identified pathogen. SUMMARY OF BACKGROUND DATA: PSI is associated with significant risks for morbidity and mortality. Specific antibiotic treatment has been considered a key to successful medical treatment; however, clinicians frequently treat patients with PSI without an identified agent. A paucity of data is available comparing the clinical outcomes of patients with or without an identified pathogen. MATERIALS AND METHODS: The records of 97 consecutive patients discharged from a University Hospital with the diagnosis of PSI during a 14-year period were retrospectively reviewed. Patients' demographics, etiological agent, comorbidities, site of infection, white blood cell count, erythrocyte sedimentation rate, C-reactive protein at the time of presentation, neurological impairment, length of hospital stay, and mortality were registered to compare the clinical outcomes of patients with an identified pathogen with those of patients without an identified agent. RESULTS: The causative organism was identified in 74 patients (76.3%). Patients with microbiological diagnosis were younger, and a larger percentage of them exhibited elevated C-reactive protein value; however, they were not different from those without an identified agent in terms of sex, site of infection, comorbidities, and the presence of a concomitant infection. Our study could not demonstrate different neurological outcomes, length of stay, or mortality rates among the 2 groups. CONCLUSIONS: In a large series of patients with PSI, we did not demonstrate differences in clinical outcomes using empirical antibiotics in patients without an identified pathogen compared with patients with an identified microbiological agent receiving specific antibiotics. Future prospective multicenter studies should be conducted to obtain an answer to this important clinical question.


Assuntos
Antibacterianos/uso terapêutico , Doenças da Coluna Vertebral/tratamento farmacológico , Doenças da Coluna Vertebral/microbiologia , Adulto , Fatores Etários , Idoso , Sedimentação Sanguínea , Proteína C-Reativa/metabolismo , Feminino , Humanos , Tempo de Internação , Contagem de Leucócitos , Masculino , Pessoa de Meia-Idade , Doenças do Sistema Nervoso/etiologia , Osteomielite/tratamento farmacológico , Osteomielite/microbiologia , Reação em Cadeia da Polimerase , Estudos Prospectivos , Estudos Retrospectivos , Fatores Sexuais , Doenças da Coluna Vertebral/mortalidade , Resultado do Tratamento
9.
Neurocirugia (Astur) ; 26(3): 143-6, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25708474

RESUMO

INTRODUCTION: There are published cases of cerebral hemorrhage secondary to vascular alterations caused by choriocarcinoma metastases. However, it is extremely rare to find this type of bleeding secondary to an association of such a metastasis with a brain arteriovenous malformation (AVM). CLINICAL CASE: We present the case of a 19-year-old male who came to the Emergency Department complaining of intense headache of abrupt onset. His physical examination revealed a striking increase in size of the right testicle of tumoral origin. Chest X-ray evidenced metastasis to the lungs and a brain CT showed a frontal hemorrhage of probably metastatic origin. The latter eventually progressed to cause the death of the patient. Pathology of the brain hematoma disclosed a choriocarcinoma within the brain AVM nidus. CONCLUSIONS: The case presented is an extremely rare confluence of choriocarcinoma brain metastasis within an AVM. The hemorrhagic onset could have been secondary to bleeding from either of the two histological components of the subjacent mixed pathological lesion.


Assuntos
Hemorragia Cerebral/etiologia , Coriocarcinoma/complicações , Coriocarcinoma/secundário , Malformações Arteriovenosas Intracranianas/complicações , Neoplasias Vasculares/complicações , Neoplasias Vasculares/secundário , Hemorragia Cerebral/patologia , Evolução Fatal , Humanos , Masculino , Neoplasias Testiculares/complicações , Neoplasias Testiculares/patologia , Adulto Jovem
10.
Int Orthop ; 38(8): 1723-9, 2014 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-24271502

RESUMO

PURPOSE: The number of citations of an article is a marker of its academic influence. Several medical specialties, including orthopaedics, have ranked the articles with more citations. We identified the 50 most cited orthopaedic articles from Latin-America and analyzed the characteristics that made them citable. METHODS: Science Citation Index Expanded was searched for citations of articles originated in Latin-America, published in any of the 63 journals in the category "Orthopaedics" from 1988 to 2013. We created a list ranking the 50 most commonly cited articles and determined the citation density (Citations/years since publication). Information noted for each article included authors, year of publication, country of origin, source journal, article type, and field of research. RESULTS: Latin-American countries were the origin of 1% of orthopaedic articles. The top 50 most cited articles had between 29 and 150 citations (mean, 44.48); the citation density ranged from 1.43 to 15.5 citations/years (mean, 5.25). The articles were published in 19 of the 63 journals (11 general and eight sub-specialty journals), and all were published in English. Most articles (n = 29) were published in 2000 or later. The majority were clinical articles (n=40), and the most common fields were arthroscopy (n = 15) and hip surgery (n = 13). The top 50 articles originated mainly from Brazil (n = 20) and Argentina (n = 15). CONCLUSIONS: This top 50 list displays articles that have become important references for the orthopaedic scientific community. Researchers may use this work to make their future publications more influential on future investigators.


Assuntos
Fator de Impacto de Revistas , Ortopedia , Editoração/estatística & dados numéricos , Artroplastia de Quadril , Artroscopia , Humanos , América Latina
11.
Neurocirugia (Astur) ; 25(3): 136-9, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24630732

RESUMO

OBJECTIVE: To report a unique case of haemorrhagic presentation of a chiasmal and optic tract glioma (OPG) appearing as an extra-axial lesion on MRI scans. CASE REPORT: A 30-year-old female with a preoperative radiological diagnosis of dermoid cyst was operated. No lesion was found in the chiasmal or carotid cisterns within the operative field. The right posterolateral corner of the chiasma and the beginning of the right optic tract appeared swollen. The area was incised and a haemorrhagic fluid poured through the opening. Several samples were taken and the pathological diagnosis was of pilocytic glioma. CONCLUSIONS: We present a unique case of chiasmal bleeding into the optic pathway secondary to an optic glioma which radiologically mimicked an intracisternal cyst. In similar cases, rapid clinical evolution of the symptoms may be vital for the differential diagnosis. Surgery is warranted to prevent permanent damage to the visual pathway.


Assuntos
Hemorragia/etiologia , Quiasma Óptico , Doenças do Nervo Óptico/etiologia , Glioma do Nervo Óptico/complicações , Adulto , Feminino , Humanos , Imageamento por Ressonância Magnética , Glioma do Nervo Óptico/diagnóstico
12.
Eur Spine J ; 22(12): 2815-20, 2013 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-24013780

RESUMO

PURPOSE: Cervical spine pyogenic infections are unusual compared to other vertebral segments, but they can be associated to worse clinical outcomes. We compared all patients with cervical spine pyogenic infections to those with thoracolumbar involvement in terms of epidemiology, prognostic factors and clinical outcomes. METHODS: We retrospectively reviewed all patients discharged from our institution with diagnosis of pyogenic spinal infections (PSI) during a 14-year period. Patients' demographics, etiologic agent, co-morbidities, site of infection, white blood cell count, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) at time of presentation, neurological impairment and mortality were registered to compare clinical outcomes of patients with PSI affecting the cervical spine and other segments. RESULTS: We studied 102 patients with PSI. Nineteen (18.6 %) had cervical involvement; 73.7 % of them were males, with a mean age of 65.22 years. 89.7 % of them presented spondylodiscitis; 12 patients (63.2 %) exhibited a one segment involvement (C5-C6 being the most common), and 11 patients presented an epidural abscess. Thirteen patients (68.4 %) exhibited neurological deficit. Seventeen patients (89.5 %) presented elevated ESR and CRP, while 12 patients (63.2 %) exhibited leukocytosis. The causative organism was identified in 17 patients (89.5 %). Despite similar baseline characteristics, compared to PSI in other locations, patients with cervical PSI presented significantly more neurological involvement (68.4 vs. 41 %; p = 0.03), they more often required surgical treatment (84.2 vs. 46.3 %; p < 0.01), and they had and increased mortality (21.1 % compared to 3.6 %; p = 0.02). CONCLUSION: An early diagnosis and prompt treatment should be the goal treating cervical PSI, considering the potential devastating complications and increased mortality.


Assuntos
Infecções Bacterianas/diagnóstico , Vértebras Cervicais , Espondilite/diagnóstico , Idoso , Infecções Bacterianas/epidemiologia , Infecções Bacterianas/microbiologia , Infecções Bacterianas/terapia , Biomarcadores/metabolismo , Proteína C-Reativa/metabolismo , Comorbidade , Discite/diagnóstico , Discite/epidemiologia , Discite/terapia , Diagnóstico Precoce , Abscesso Epidural/diagnóstico , Abscesso Epidural/epidemiologia , Abscesso Epidural/terapia , Feminino , Humanos , Incidência , Vértebras Lombares , Masculino , Pessoa de Meia-Idade , Osteomielite/diagnóstico , Osteomielite/epidemiologia , Osteomielite/terapia , Estudos Retrospectivos , Espondilite/epidemiologia , Espondilite/microbiologia , Espondilite/terapia , Vértebras Torácicas , Resultado do Tratamento
13.
Data Brief ; 50: 109617, 2023 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-37808543

RESUMO

Glioblastoma, a highly aggressive primary brain tumor, is associated with poor patient outcomes. Although magnetic resonance imaging (MRI) plays a critical role in diagnosing, characterizing, and forecasting glioblastoma progression, public MRI repositories present significant drawbacks, including insufficient postoperative and follow-up studies as well as expert tumor segmentations. To address these issues, we present the "Río Hortega University Hospital Glioblastoma Dataset (RHUH-GBM)," a collection of multiparametric MRI images, volumetric assessments, molecular data, and survival details for glioblastoma patients who underwent total or near-total enhancing tumor resection. The dataset features expert-corrected segmentations of tumor subregions, offering valuable ground truth data for developing algorithms for postoperative and follow-up MRI scans.

14.
Injury ; 54 Suppl 6: 110724, 2023 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-38143142

RESUMO

INTRODUCTION: hip fracture represents a global health problem, with a high morbidity and mortality rate and an increasing incidence. The treatment of trochanteric fractures is reduction and osteosynthesis, and implant selection depends mainly on the stability of the fracture and lateral wall competence. Lateral wall competence has gained relevance in recent years, which led to the modification of the AO/OTA classification. However, determination of lateral wall integrity is difficult from plain radiographs; the influence of images with traction on its measurement has not been evaluated. METHODS: prospective concordance study, emergency and post-traction radiographs of 65 patients with trochanteric fracture were evaluated by six orthopedic surgeons independently, measuring the lateral wall, classifying the fracture according to the AO/OTA 2018 classification and selecting the implant for osteosynthesis. A comparison of incompetent to intact lateral wall proportion between each image set was made. Secondary outcomes were the inter-observer correlation of lateral wall measurement and inter-observer agreement of classification and implant choice. RESULTS: the proportion of patients with an incompetent lateral wall in emergency x-ray was 37.43% (CI 95% 0.326-0.422), while the proportion in post-traction fluoroscopy was 15% (CI 95% 0.115-0.185), with a statistically significant difference (p < 0.001). 40.1% of patients with an incompetent lateral wall changed to an intact one. Inter-observer correlation for the lateral wall thickness was 0.399 (CI 95% 0.292-0.519) in emergency x-ray and 0.658 (CI 95% 0.564-0.748) in post-traction fluoroscopy, with a substantial agreement. Inter-observer agreement for the fracture classification was fair to moderate using emergency x-ray (κ 0.369 95%CI 0.330-0.408) and fair to moderate with post-traction fluoroscopy (κ 0.400, 95% CI 0.334-0.466). CONCLUSION: traction images significantly change the measurement of the lateral wall in trochanteric fractures, changing from an incompetent to a competent wall in 40% of patients. The correct classification of trochanteric fractures is crucial to make the best decision when deciding which implant to use, and the measurement of the lateral wall is determinant in the actual AO/OTA classification. Therefore, traction images appear as necessary for correct decision-making.


Assuntos
Fraturas do Quadril , Tração , Humanos , Estudos Prospectivos , Variações Dependentes do Observador , Fraturas do Quadril/diagnóstico por imagem , Fraturas do Quadril/cirurgia , Radiografia , Reprodutibilidade dos Testes
15.
Cancers (Basel) ; 15(6)2023 Mar 22.
Artigo em Inglês | MEDLINE | ID: mdl-36980783

RESUMO

The globally accepted surgical strategy in glioblastomas is removing the enhancing tumor. However, the peritumoral region harbors infiltration areas responsible for future tumor recurrence. This study aimed to evaluate a predictive model that identifies areas of future recurrence using a voxel-based radiomics analysis of magnetic resonance imaging (MRI) data. This multi-institutional study included a retrospective analysis of patients diagnosed with glioblastoma who underwent surgery with complete resection of the enhancing tumor. Fifty-five patients met the selection criteria. The study sample was split into training (N = 40) and testing (N = 15) datasets. Follow-up MRI was used for ground truth definition, and postoperative structural multiparametric MRI was used to extract voxel-based radiomic features. Deformable coregistration was used to register the MRI sequences for each patient, followed by segmentation of the peritumoral region in the postoperative scan and the enhancing tumor in the follow-up scan. Peritumoral voxels overlapping with enhancing tumor voxels were labeled as recurrence, while non-overlapping voxels were labeled as nonrecurrence. Voxel-based radiomic features were extracted from the peritumoral region. Four machine learning-based classifiers were trained for recurrence prediction. A region-based evaluation approach was used for model evaluation. The Categorical Boosting (CatBoost) classifier obtained the best performance on the testing dataset with an average area under the curve (AUC) of 0.81 ± 0.09 and an accuracy of 0.84 ± 0.06, using region-based evaluation. There was a clear visual correspondence between predicted and actual recurrence regions. We have developed a method that accurately predicts the region of future tumor recurrence in MRI scans of glioblastoma patients. This could enable the adaptation of surgical and radiotherapy treatment to these areas to potentially prolong the survival of these patients.

16.
Int Orthop ; 36(12): 2571-6, 2012 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-23129225

RESUMO

PURPOSE: The Surgical Apgar Score (SAS) is a simple tally based on intra-operative heart rate, blood pressure and blood loss; it predicts 30-day major postoperative complications and mortality in different surgical fields, but no validation has been performed in general orthopaedic surgery. METHODS: A prospective assessment of the SAS in 723 consecutive patients undergoing major and intermediate orthopaedic procedures was performed in an 18-month period. The SAS was calculated immediately after surgery, and the occurrence of major complications or death was registered within a 30-day follow-up. RESULTS: Thirty-seven patients had ≥1 complication (5.12 %). The complication rate did not augment as the score decreased (SAS 9-10 = 6.56 %; SAS 7-8 = 2.62 %; SAS 5-6 = 7.21 %; SAS ≤4 = 10.2 %), the relative risk did not augment as the score decreased and the likelihood ratio did not increase with decreasing SAS values, except in the subgroup of patients undergoing spine surgery. The C-statistic was 0.59 (95 % confidence interval 0.48-0.69), a weak discriminatory value. Using a threshold of 7 to define high-risk and low-risk patients, the SAS allowed risk stratification only for spine surgery. CONCLUSIONS: The SAS does not predict 30-day major complications and death in patients undergoing general orthopaedic surgery, but it is useful in the subgroup of patients undergoing spine surgery.


Assuntos
Monitorização Intraoperatória/métodos , Monitorização Intraoperatória/normas , Procedimentos Ortopédicos/efeitos adversos , Procedimentos Ortopédicos/mortalidade , Complicações Pós-Operatórias/epidemiologia , Perda Sanguínea Cirúrgica/fisiopatologia , Pressão Sanguínea/fisiologia , Seguimentos , Indicadores Básicos de Saúde , Frequência Cardíaca/fisiologia , Humanos , Valor Preditivo dos Testes , Estudos Prospectivos , Medição de Risco , Taxa de Sobrevida
17.
J Knee Surg ; 35(14): 1610-1618, 2022 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-33932950

RESUMO

Calipered kinematically aligned (KA) total knee arthroplasty (TKA) restores the patient's prearthritic joint lines and sets internal-external rotation of the tibial component parallel to the flexion-extension (FE) plane, which is not a mechanical alignment (MA) target. Two asymmetric tibial components designed for MA set the tibial component to either a femoral component (FC) target or a tibial tubercle (TT) target. The study determined the optimal asymmetric tibial component to use with KA as the one with smaller IE deviation from the MA target, greater coverage of tibial resection, and lower incidence of cortical overhang. The study included 40 patients treated with bilateral calipered KA TKA with different asymmetric tibial components in opposite knees. A best-fit of a kinematic tibial template to the tibial resection set the template's slot parallel to the knee's FE plane. Each asymmetric tibial component's anterior-posterior (AP) axis was set parallel to the slot. Computer tomography analysis determined the IE deviation (-internal/+ external) of each tibial component from its MA target, tibial resection coverage by the baseplate and insert, and incidence of cortical overhang. The patient-reported Forgotten Joint Score (FJS) and Oxford Knee Score (OKS) determined outcomes. The mean IE deviation from the MA target was 2 degrees external for the FC-target asymmetric tibial component and -8 degrees internal for the TT-target asymmetric tibial component (p < 0.001). Tibial resection coverage by the baseplate (insert) was 88% (84%) for the FC target and 84% (79%) for the TT target (p < 0.001 for baseplate and insert). The FC target insert covered 3 mm more of the posterolateral resection (p < 0.001). Posteromedial coverage was comparable. The incidence of cortical overhang was 2.5% for each baseplate. There was no difference in FJS and OKS. When performing calipered KA, the more optimal design was the asymmetric tibial component with the FC target because of the smaller deviation from its MA target and the greater coverage of the tibial resection by the baseplate and insert.


Assuntos
Artroplastia do Joelho , Prótese do Joelho , Osteoartrite do Joelho , Humanos , Artroplastia do Joelho/métodos , Articulação do Joelho/cirurgia , Tíbia/cirurgia , Fenômenos Biomecânicos , Incidência , Prótese do Joelho/efeitos adversos , Osteoartrite do Joelho/cirurgia , Osteoartrite do Joelho/etiologia
18.
J Pers Med ; 12(9)2022 Sep 07.
Artigo em Inglês | MEDLINE | ID: mdl-36143253

RESUMO

BACKGROUND: Unrestricted caliper-verified kinematically aligned (KA) TKA restores patient's prearthritic coronal and sagittal alignments, which have a wide range containing outliers that concern the surgeon practicing mechanical alignment (MA). Therefore, knowing which radiographic parameters are associated with dissatisfaction could help a surgeon decide whether to rely on them as criteria for revising an unhappy patient with a primary KA TKA using MA principles. Hence, we determined whether the femoral mechanical angle (FMA), hip-knee-ankle angle (HKAA), tibial mechanical angle (TMA), tibial slope angle (TSA), and the indicators of patellofemoral tracking, including patella tilt angle (PTA) and the lateral undercoverage of the trochlear resection (LUCTR), are associated with clinical outcome scores. METHODS: Forty-three patients with a CT scan and skyline radiograph after a KA TKA with PCL retention and medial stabilized design were analyzed. Linear regression determined the strength of the association between the FMA, HKA angle, PTS, PTA, and LUCTR and the forgotten joint score (FJS), Oxford knee score (OKS), and KOOS Jr score obtained at a mean of 23 months. RESULTS: There was no correlation between the FMA (range 2° varus to -10° valgus), HKAA (range 10° varus to -9° valgus), TMA (range 10° varus to -0° valgus), TSA (range 14° posterior to -4° anterior), PTA (range, -10° medial to 14° lateral), and the LUCTR resection (range 2 to 9 mm) and the FJS (median 83), the OKS (median 44), and the KOOS Jr (median 85) (r = 0.000 to 0.079). CONCLUSIONS: Surgeons should be cautious about using postoperative FMA, HKAA, TMA, TSA, PTA, and LUCTR values within the present study's reported ranges to explain success and dissatisfaction after KA TKA.

19.
Injury ; 53(2): 514-518, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-34991863

RESUMO

BACKGROUND: Sacral fractures treatment frequently involves both spine and pelvic trauma surgeons; therefore, a consistent communication among surgical specialists is required. We independently assessed the new AOSpine sacral fracture classification's agreement from the perspective of spine and pelvic trauma surgeons. METHODS: Complete computerized tomography (CT) scans of 80 patients with sacral fractures were selected and classified using the new AOSpine sacral classification system by six spine surgeons and three pelvic trauma surgeons. After four weeks, the 80 cases were presented and reassessed by the same raters in a new random sequence. The Kappa coefficient (κ) was used to measure the inter-and intra-observer agreement. RESULTS: The inter-observer agreement considering the fracture severity types (A, B, or C) was substantial for spine surgeons (κ= 0.68 [0.63 - 0.72]) and pelvic trauma surgeons (κ= 0.74 (0.64 - 0.84). Regarding the subtypes, both groups achieved moderate agreement with κ= 0.52 (0.49 - 0.54) for spine surgeons and κ= 0.51 (0.45 - 0.57) for pelvic trauma surgeons. The intra-observer agreement considering the fracture types was substantial for spine surgeons (κ= 0.74 [0.63 - 0.75]) and almost perfect for pelvic trauma surgeons (κ= 0.84 [0.74 - 0.93]). Concerning the subtypes, both groups achieved substantial agreement with, κ= 0.61 (0.56 - 0.67) for spine surgeons and κ= 0.68 (0.62 - 0.74) for pelvic trauma surgeons. CONCLUSION: This classification allows an adequate communication for spine surgeons and pelvic trauma surgeons at the fracture severity type, but the agreement is only moderate at the subtype level. Future prospective studies are required to evaluate whether this classification allows for treatment recommendations and establishing prognosis in patients with sacral fractures.


Assuntos
Fraturas da Coluna Vertebral , Cirurgiões , Humanos , Variações Dependentes do Observador , Reprodutibilidade dos Testes , Sacro/diagnóstico por imagem , Sacro/cirurgia , Fraturas da Coluna Vertebral/diagnóstico por imagem , Fraturas da Coluna Vertebral/cirurgia
20.
J Knee Surg ; 34(13): 1486-1494, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-32403149

RESUMO

There are no reports of in vivo internal-external (I-E) rotational alignment and coverage of the proximal tibia after performing a best-fit method of an anatomically designed and asymmetrically shaped tibial baseplate during calipered kinematically aligned (KA) total knee arthroplasty (TKA). We hypothesized that a best-fit plane sets the anterior-posterior (A-P) axis of the anatomic baseplate closely parallel to the flexion-extension (F-E) plane of the knee and covers a high percentage of the proximal tibia. A total of 145 consecutive primary TKAs were prospectively collected. The calipered KA method and verification checks set the positions and orientations of the components without ligament release in all knees without restrictions on the preoperative deformities. A best-fit method selected one of six trials of anatomic baseplates that maximized coverage and set I-E rotation parallel to and within the cortical edge of the proximal tibia. The angle between the transverse axes of the components (i.e., the deviation of the A-P axis of the anatomic baseplate from the F-E plane of the native knee) and the cross-sectional area (CSA) of the proximal tibia were measured on postoperative computerized tomographic scans. The mean deviation of the anatomic baseplate from the F-E plane was 2-degree external ± 5 degrees. The mean coverage of the proximal tibia was 87 ± 6% (CSA of baseplate from the manufacturer/CSA of proximal tibia × 100). The anatomic baseplate and best-fit method adequately set I-E rotation of the baseplate closely parallel to the F-E plane of the knee and cover a high percentage of the proximal tibia.


Assuntos
Artroplastia do Joelho , Prótese do Joelho , Fenômenos Biomecânicos , Humanos , Articulação do Joelho/diagnóstico por imagem , Articulação do Joelho/cirurgia , Rotação , Tíbia/diagnóstico por imagem , Tíbia/cirurgia
SELEÇÃO DE REFERÊNCIAS
Detalhe da pesquisa