Detalhe da pesquisa
1.
TGF-ß2 silencing to target biliary-derived liver diseases.
Gut
; 69(9): 1677-1690, 2020 09.
Artigo
Inglês
| MEDLINE | ID: mdl-31992593
2.
Progesterone receptor membrane component 1 regulates lipid homeostasis and drives oncogenic signaling resulting in breast cancer progression.
Breast Cancer Res
; 22(1): 75, 2020 07 13.
Artigo
Inglês
| MEDLINE | ID: mdl-32660617
3.
Copy number variation profiling in pharmacogenes using panel-based exome resequencing and correlation to human liver expression.
Hum Genet
; 139(2): 137-149, 2020 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-31786673
4.
Polycyclic Aromatic Hydrocarbons Activate the Aryl Hydrocarbon Receptor and the Constitutive Androstane Receptor to Regulate Xenobiotic Metabolism in Human Liver Cells.
Int J Mol Sci
; 22(1)2020 Dec 31.
Artigo
Inglês
| MEDLINE | ID: mdl-33396476
5.
Systemic regulation of bilirubin homeostasis: Potential benefits of hyperbilirubinemia.
Hepatology
; 67(4): 1609-1619, 2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29059457
6.
Factors Affecting Interindividual Variability of Hepatic UGT2B17 Protein Expression Examined Using a Novel Specific Monoclonal Antibody.
Drug Metab Dispos
; 47(5): 444-452, 2019 05.
Artigo
Inglês
| MEDLINE | ID: mdl-30819787
7.
Regulation of Drug Metabolism by the Interplay of Inflammatory Signaling, Steatosis, and Xeno-Sensing Receptors in HepaRG Cells.
Drug Metab Dispos
; 46(4): 326-335, 2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29330220
8.
Direct Quantification of Cytochromes P450 and Drug Transporters-A Rapid, Targeted Mass Spectrometry-Based Immunoassay Panel for Tissues and Cell Culture Lysates.
Drug Metab Dispos
; 46(4): 387-396, 2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29343608
9.
The formation of estrogen-like tamoxifen metabolites and their influence on enzyme activity and gene expression of ADME genes.
Arch Toxicol
; 92(3): 1099-1112, 2018 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-29285606
10.
Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes.
Biochim Biophys Acta
; 1859(9): 1218-1227, 2016 09.
Artigo
Inglês
| MEDLINE | ID: mdl-26994748
11.
Coordinating Role of RXRα in Downregulating Hepatic Detoxification during Inflammation Revealed by Fuzzy-Logic Modeling.
PLoS Comput Biol
; 12(1): e1004431, 2016 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-26727233
12.
Model-Based Characterization of Inflammatory Gene Expression Patterns of Activated Macrophages.
PLoS Comput Biol
; 12(7): e1005018, 2016 07.
Artigo
Inglês
| MEDLINE | ID: mdl-27464342
13.
Methyleugenol DNA adducts in human liver are associated with SULT1A1 copy number variations and expression levels.
Arch Toxicol
; 91(10): 3329-3339, 2017 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-28326452
14.
Correction to: Progesterone receptor membrane component 1 regulates lipid homeostasis and drives oncogenic signaling resulting in breast cancer progression.
Breast Cancer Res
; 23(1): 13, 2021 Jan 28.
Artigo
Inglês
| MEDLINE | ID: mdl-33509243
15.
Omics and drug response.
Annu Rev Pharmacol Toxicol
; 53: 475-502, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23140244
16.
Inflammatory regulation of steroid sulfatase: A novel mechanism to control estrogen homeostasis and inflammation in chronic liver disease.
J Hepatol
; 64(1): 44-52, 2016 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-26220752
17.
Association between CYP2E1 polymorphisms and risk of differentiated thyroid carcinoma.
Arch Toxicol
; 90(12): 3099-3109, 2016 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-26783003
18.
Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data.
Lancet Oncol
; 16(16): 1639-50, 2015 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-26603945
19.
Activating and Inhibitory Functions of WNT/ß-Catenin in the Induction of Cytochromes P450 by Nuclear Receptors in HepaRG Cells.
Mol Pharmacol
; 87(6): 1013-20, 2015 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-25824487
20.
Human sterol regulatory element-binding protein 1a contributes significantly to hepatic lipogenic gene expression.
Cell Physiol Biochem
; 35(2): 803-15, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25634759