Pesquisa | Secretaria de Estado da Saúde

1.

Antagonistic RALF peptides control an intergeneric hybridization barrier on Brassicaceae stigmas.

Lan, Zijun; Song, Zihan; Wang, Zhijuan; Li, Ling; Liu, Yiqun; Zhi, Shuaihua; Wang, Ruihan; Wang, Jizong; Li, Qiyun; Bleckmann, Andrea; Zhang, Li; Dresselhaus, Thomas; Dong, Juan; Gu, Hongya; Zhong, Sheng; Qu, Li-Jia.

Cell ; 186(22): 4773-4787.e12, 2023 10 26.

Artigo Inglês | MEDLINE | ID: mdl-37806310

2.

The evolution and diversification of oakleaf butterflies.

Wang, Shuting; Teng, Dequn; Li, Xueyan; Yang, Peiwen; Da, Wa; Zhang, Yiming; Zhang, Yubo; Liu, Guichun; Zhang, Xinshuang; Wan, Wenting; Dong, Zhiwei; Wang, Donghui; Huang, Shun; Jiang, Zhisheng; Wang, Qingyi; Lohman, David J; Wu, Yongjie; Zhang, Linlin; Jia, Fenghai; Westerman, Erica; Zhang, Li; Wang, Wen; Zhang, Wei.

Cell ; 185(17): 3138-3152.e20, 2022 08 18.

Artigo Inglês | MEDLINE | ID: mdl-35926506

3.

A second-generation M1-polarized CAR macrophage with antitumor efficacy.

Lei, Anhua; Yu, Hua; Lu, Shan; Lu, Hengxing; Ding, Xizhong; Tan, Tianyu; Zhang, Hailing; Zhu, Mengmeng; Tian, Lin; Wang, Xudong; Su, Siyu; Xue, Dixuan; Zhang, Shaolong; Zhao, Wei; Chen, Yuge; Xie, Wanrun; Zhang, Li; Zhu, Yuqing; Zhao, Jing; Jiang, Wenhong; Church, George; Chan, Francis Ka-Ming; Gao, Zhihua; Zhang, Jin.

Nat Immunol ; 25(1): 102-116, 2024 Jan.

Artigo Inglês | MEDLINE | ID: mdl-38012418

4.

Pathogenic ubiquitination of GSDMB inhibits NK cell bactericidal functions.

Hansen, Justin M; de Jong, Maarten F; Wu, Qi; Zhang, Li-Shu; Heisler, David B; Alto, Laura T; Alto, Neal M.

Cell ; 184(12): 3178-3191.e18, 2021 06 10.

Artigo Inglês | MEDLINE | ID: mdl-34022140

5.

SARS-CoV-2 501Y.V2 variants lack higher infectivity but do have immune escape.

Li, Qianqian; Nie, Jianhui; Wu, Jiajing; Zhang, Li; Ding, Ruxia; Wang, Haixin; Zhang, Yue; Li, Tao; Liu, Shuo; Zhang, Mengyi; Zhao, Chenyan; Liu, Huan; Nie, Lingling; Qin, Haiyang; Wang, Meng; Lu, Qiong; Li, Xiaoyu; Liu, Junkai; Liang, Haoyu; Shi, Yi; Shen, Yuelei; Xie, Liangzhi; Zhang, Linqi; Qu, Xiaowang; Xu, Wenbo; Huang, Weijin; Wang, Youchun.

Cell ; 184(9): 2362-2371.e9, 2021 04 29.

Artigo Inglês | MEDLINE | ID: mdl-33735608

6.

Exhausted intratumoral VÎ´2^- Î³Î´ T cells in human kidney cancer retain effector function.

Rancan, Chiara; Arias-Badia, Marcel; Dogra, Pranay; Chen, Brandon; Aran, Dvir; Yang, Hai; Luong, Diamond; Ilano, Arielle; Li, Jacky; Chang, Hewitt; Kwek, Serena S; Zhang, Li; Lanier, Lewis L; Meng, Maxwell V; Farber, Donna L; Fong, Lawrence.

Nat Immunol ; 24(4): 612-624, 2023 04.

Artigo Inglês | MEDLINE | ID: mdl-36928415

7.

The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity.

Li, Qianqian; Wu, Jiajing; Nie, Jianhui; Zhang, Li; Hao, Huan; Liu, Shuo; Zhao, Chenyan; Zhang, Qi; Liu, Huan; Nie, Lingling; Qin, Haiyang; Wang, Meng; Lu, Qiong; Li, Xiaoyu; Sun, Qiyu; Liu, Junkai; Zhang, Linqi; Li, Xuguang; Huang, Weijin; Wang, Youchun.

Cell ; 182(5): 1284-1294.e9, 2020 09 03.

Artigo Inglês | MEDLINE | ID: mdl-32730807

8.

Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia.

Wang, Jun; Xu, Yanhui; Chen, Zhanghua; Liang, Jiankun; Lin, Zefeng; Liang, Huiying; Xu, Yiping; Wu, Qi; Guo, Xuanjie; Nie, Junli; Lu, Bingtai; Huang, Bing; Xian, Huifang; Wang, Xiaohui; Wu, Qiang; Zeng, Jixiao; Chai, Chengwei; Zhang, Meixue; Lin, Yuzhen; Zhang, Li; Zhao, Shanmeizi; Tong, Yanlu; Zeng, Liang; Gu, Xiaoqiong; Chen, Zhuang-Gui; Yi, Shuhong; Zhang, Tong; Delfouneso, David; Zhang, Yan; Nutt, Stephen L; Lew, Andrew M; Lu, Liwei; Bai, Fan; Xia, Huimin; Wen, Zhe; Zhang, Yuxia.

Cell ; 183(7): 1867-1883.e26, 2020 12 23.

Artigo Inglês | MEDLINE | ID: mdl-33248023

9.

Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways.

Huang, Bing; Chen, Zhanghua; Geng, Lanlan; Wang, Jun; Liang, Huiying; Cao, Yujie; Chen, Huan; Huang, Wanming; Su, Meiling; Wang, Hanqing; Xu, Yanhui; Liu, Yukun; Lu, Bingtai; Xian, Huifang; Li, Huiwen; Li, Huilin; Ren, Lu; Xie, Jing; Ye, Liping; Wang, Hongli; Zhao, Junhong; Chen, Peiyu; Zhang, Li; Zhao, Shanmeizi; Zhang, Ting; Xu, Banglao; Che, Di; Si, Wenyue; Gu, Xiaoqiong; Zeng, Liang; Wang, Yong; Li, Dingyou; Zhan, Yifan; Delfouneso, David; Lew, Andrew M; Cui, Jun; Tang, Wai Ho; Zhang, Yan; Gong, Sitang; Bai, Fan; Yang, Min; Zhang, Yuxia.

Cell ; 179(5): 1160-1176.e24, 2019 11 14.

Artigo Inglês | MEDLINE | ID: mdl-31730855

10.

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.

Quigley, David A; Dang, Ha X; Zhao, Shuang G; Lloyd, Paul; Aggarwal, Rahul; Alumkal, Joshi J; Foye, Adam; Kothari, Vishal; Perry, Marc D; Bailey, Adina M; Playdle, Denise; Barnard, Travis J; Zhang, Li; Zhang, Jin; Youngren, Jack F; Cieslik, Marcin P; Parolia, Abhijit; Beer, Tomasz M; Thomas, George; Chi, Kim N; Gleave, Martin; Lack, Nathan A; Zoubeidi, Amina; Reiter, Robert E; Rettig, Matthew B; Witte, Owen; Ryan, Charles J; Fong, Lawrence; Kim, Won; Friedlander, Terence; Chou, Jonathan; Li, Haolong; Das, Rajdeep; Li, Hui; Moussavi-Baygi, Ruhollah; Goodarzi, Hani; Gilbert, Luke A; Lara, Primo N; Evans, Christopher P; Goldstein, Theodore C; Stuart, Joshua M; Tomlins, Scott A; Spratt, Daniel E; Cheetham, R Keira; Cheng, Donavan T; Farh, Kyle; Gehring, Julian S; Hakenberg, Jörg; Liao, Arnold; Febbo, Philip G.

Cell ; 174(3): 758-769.e9, 2018 07 26.

Artigo Inglês | MEDLINE | ID: mdl-30033370

11.

Sequencing of N⁶-methyl-deoxyadenosine at single-base resolution across the mammalian genome.

Feng, Xinran; Cui, Xiaolong; Zhang, Li-Sheng; Ye, Chang; Wang, Pingluan; Zhong, Yuhao; Wu, Tong; Zheng, Zhong; He, Chuan.

Mol Cell ; 84(3): 596-610.e6, 2024 Feb 01.

Artigo Inglês | MEDLINE | ID: mdl-38215754

12.

The deubiquitinase Otub1 controls the activation of CD8⁺ T cells and NK cells by regulating IL-15-mediated priming.

Zhou, Xiaofei; Yu, Jiayi; Cheng, Xuhong; Zhao, Baoyu; Manyam, Ganiraju C; Zhang, Li; Schluns, Kimberly; Li, Pingwei; Wang, Jing; Sun, Shao-Cong.

Nat Immunol ; 20(7): 879-889, 2019 07.

Artigo Inglês | MEDLINE | ID: mdl-31182807

13.

Author Correction: A second-generation M1-polarized CAR macrophage with antitumor efficacy.

Lei, Anhua; Yu, Hua; Lu, Shan; Lu, Hengxing; Ding, Xizhong; Tan, Tianyu; Zhang, Hailing; Zhu, Mengmeng; Tian, Lin; Wang, Xudong; Su, Siyu; Xue, Dixuan; Zhang, Shaolong; Zhao, Wei; Chen, Yuge; Xie, Wanrun; Zhang, Li; Zhu, Yuqing; Zhao, Jing; Jiang, Wenhong; Church, George; Chan, Francis Ka-Ming; Gao, Zhihua; Zhang, Jin.

Nat Immunol ; 25(3): 576, 2024 Mar.

Artigo Inglês | MEDLINE | ID: mdl-38110523

14.

Brain endothelial GSDMD activation mediates inflammatory BBB breakdown.

Wei, Chao; Jiang, Wei; Wang, Ruiyu; Zhong, Haoyu; He, Huabin; Gao, Xinwei; Zhong, Shilin; Yu, Fengting; Guo, Qingchun; Zhang, Li; Schiffelers, Lisa D J; Zhou, Bin; Trepel, Martin; Schmidt, Florian I; Luo, Minmin; Shao, Feng.

Nature ; 2024 Apr 17.

Artigo Inglês | MEDLINE | ID: mdl-38632402

15.

The long noncoding RNA glycoLINC assembles a lower glycolytic metabolon to promote glycolysis.

Zhu, Youming; Jin, Lei; Shi, Ronghua; Li, Jinming; Wang, Yan; Zhang, Li; Liang, Chao-Zhao; Narayana, Vinod K; De Souza, David P; Thorne, Rick F; Zhang, Li Rong; Zhang, Xu Dong; Wu, Mian.

Mol Cell ; 82(3): 542-554.e6, 2022 02 03.

Artigo Inglês | MEDLINE | ID: mdl-35081364

16.

Uridine-derived ribose fuels glucose-restricted pancreatic cancer.

Nwosu, Zeribe C; Ward, Matthew H; Sajjakulnukit, Peter; Poudel, Pawan; Ragulan, Chanthirika; Kasperek, Steven; Radyk, Megan; Sutton, Damien; Menjivar, Rosa E; Andren, Anthony; Apiz-Saab, Juan J; Tolstyka, Zachary; Brown, Kristee; Lee, Ho-Joon; Dzierozynski, Lindsey N; He, Xi; Ps, Hari; Ugras, Julia; Nyamundanda, Gift; Zhang, Li; Halbrook, Christopher J; Carpenter, Eileen S; Shi, Jiaqi; Shriver, Leah P; Patti, Gary J; Muir, Alexander; Pasca di Magliano, Marina; Sadanandam, Anguraj; Lyssiotis, Costas A.

Nature ; 618(7963): 151-158, 2023 Jun.

Artigo Inglês | MEDLINE | ID: mdl-37198494

17.

Structural insights into the functional divergence of WhiB-like proteins in Mycobacterium tuberculosis.

Wan, Tao; Horová, Magdaléna; Beltran, Daisy Guiza; Li, Shanren; Wong, Huey-Xian; Zhang, Li-Mei.

Mol Cell ; 81(14): 2887-2900.e5, 2021 07 15.

Artigo Inglês | MEDLINE | ID: mdl-34171298

18.

Interferon-Î³ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation.

Yu, Man; Peng, Zhengxin; Qin, Min; Liu, Yang; Wang, Jingning; Zhang, Cai; Lin, Jiaming; Dong, Tianqi; Wang, Lulu; Li, Shasha; Yang, Yongqin; Xu, Shan; Guo, Wencong; Zhang, Xiao; Shi, Mingjun; Peng, Huiming; Luo, Xianwen; Zhang, Huixia; Zhang, Li; Li, Yan; Yang, Xiang-Ping; Sun, Shuguo.

Mol Cell ; 81(6): 1216-1230.e9, 2021 03 18.

Artigo Inglês | MEDLINE | ID: mdl-33606996

19.

Clonal Deletion of Tumor-Specific T Cells by Interferon-Î³ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade.

Pai, Chien-Chun Steven; Huang, John T; Lu, Xiaoqing; Simons, Donald M; Park, Chanhyuk; Chang, Anthony; Tamaki, Whitney; Liu, Eric; Roybal, Kole T; Seagal, Jane; Chen, Mingyi; Hagihara, Katsunobu; Wei, Xiao X; DuPage, Michel; Kwek, Serena S; Oh, David Y; Daud, Adil; Tsai, Katy K; Wu, Clint; Zhang, Li; Fasso, Marcella; Sachidanandam, Ravi; Jayaprakash, Anitha; Lin, Ingrid; Casbon, Amy-Jo; Kinsbury, Gillian A; Fong, Lawrence.

Immunity ; 50(2): 477-492.e8, 2019 02 19.

Artigo Inglês | MEDLINE | ID: mdl-30737146

20.

Sperm, but not oocyte, DNA methylome is inherited by zebrafish early embryos.

Jiang, Lan; Zhang, Jing; Wang, Jing-Jing; Wang, Lu; Zhang, Li; Li, Guoqiang; Yang, Xiaodan; Ma, Xin; Sun, Xin; Cai, Jun; Zhang, Jun; Huang, Xingxu; Yu, Miao; Wang, Xuegeng; Liu, Feng; Wu, Chung-I; He, Chuan; Zhang, Bo; Ci, Weimin; Liu, Jiang.

Cell ; 153(4): 773-84, 2013 May 09.

Artigo Inglês | MEDLINE | ID: mdl-23663777

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