Pesquisa | Secretaria de Estado da Saúde

1.

Human Adaptive Immunity Rescues an Inborn Error of Innate Immunity.

Israel, Laura; Wang, Ying; Bulek, Katarzyna; Della Mina, Erika; Zhang, Zhao; Pedergnana, Vincent; Chrabieh, Maya; Lemmens, Nicole A; Sancho-Shimizu, Vanessa; Descatoire, Marc; Lasseau, Théo; Israelsson, Elisabeth; Lorenzo, Lazaro; Yun, Ling; Belkadi, Aziz; Moran, Andrew; Weisman, Leonard E; Vandenesch, François; Batteux, Frederic; Weller, Sandra; Levin, Michael; Herberg, Jethro; Abhyankar, Avinash; Prando, Carolina; Itan, Yuval; van Wamel, Willem J B; Picard, Capucine; Abel, Laurent; Chaussabel, Damien; Li, Xiaoxia; Beutler, Bruce; Arkwright, Peter D; Casanova, Jean-Laurent; Puel, Anne.

Cell ; 168(5): 789-800.e10, 2017 02 23.

Artigo Inglês | MEDLINE | ID: mdl-28235196

2.

Hormone-induced enhancer assembly requires an optimal level of hormone receptor multivalent interactions.

Chen, Lizhen; Zhang, Zhao; Han, Qinyu; Maity, Barun K; Rodrigues, Leticia; Zboril, Emily; Adhikari, Rashmi; Ko, Su-Hyuk; Li, Xin; Yoshida, Shawn R; Xue, Pengya; Smith, Emilie; Xu, Kexin; Wang, Qianben; Huang, Tim Hui-Ming; Chong, Shasha; Liu, Zhijie.

Mol Cell ; 83(19): 3438-3456.e12, 2023 10 05.

Artigo Inglês | MEDLINE | ID: mdl-37738977

3.

Label-free detection and profiling of individual solution-phase molecules.

Needham, Lisa-Maria; Saavedra, Carlos; Rasch, Julia K; Sole-Barber, Daniel; Schweitzer, Beau S; Fairhall, Alex J; Vollbrecht, Cecilia H; Wan, Sushu; Podorova, Yulia; Bergsten, Anders J; Mehlenbacher, Brandon; Zhang, Zhao; Tenbrake, Lukas; Saimi, Jovanna; Kneely, Lucy C; Kirkwood, Jackson S; Pfeifer, Hannes; Chapman, Edwin R; Goldsmith, Randall H.

Nature ; 2024 May 08.

Artigo Inglês | MEDLINE | ID: mdl-38720082

4.

The HP1 homolog rhino anchors a nuclear complex that suppresses piRNA precursor splicing.

Zhang, Zhao; Wang, Jie; Schultz, Nadine; Zhang, Fan; Parhad, Swapnil S; Tu, Shikui; Vreven, Thom; Zamore, Phillip D; Weng, Zhiping; Theurkauf, William E.

Cell ; 157(6): 1353-1363, 2014 Jun 05.

Artigo Inglês | MEDLINE | ID: mdl-24906152

5.

Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade.

Dai, Xiaoming; Bu, Xia; Gao, Yang; Guo, Jianping; Hu, Jia; Jiang, Cong; Zhang, Zhao; Xu, Kexin; Duan, Jinzhi; He, Shaohui; Zhang, Jinfang; Wan, Lixin; Liu, Tianjie; Zhou, Xiaobo; Hung, Mien-Chie; Freeman, Gordon J; Wei, Wenyi.

Mol Cell ; 81(11): 2317-2331.e6, 2021 06 03.

Artigo Inglês | MEDLINE | ID: mdl-33909988

6.

Large-scale migration into Britain during the Middle to Late Bronze Age.

Patterson, Nick; Isakov, Michael; Booth, Thomas; Büster, Lindsey; Fischer, Claire-Elise; Olalde, Iñigo; Ringbauer, Harald; Akbari, Ali; Cheronet, Olivia; Bleasdale, Madeleine; Adamski, Nicole; Altena, Eveline; Bernardos, Rebecca; Brace, Selina; Broomandkhoshbacht, Nasreen; Callan, Kimberly; Candilio, Francesca; Culleton, Brendan; Curtis, Elizabeth; Demetz, Lea; Carlson, Kellie Sara Duffett; Edwards, Ceiridwen J; Fernandes, Daniel M; Foody, M George B; Freilich, Suzanne; Goodchild, Helen; Kearns, Aisling; Lawson, Ann Marie; Lazaridis, Iosif; Mah, Matthew; Mallick, Swapan; Mandl, Kirsten; Micco, Adam; Michel, Megan; Morante, Guillermo Bravo; Oppenheimer, Jonas; Özdogan, Kadir Toykan; Qiu, Lijun; Schattke, Constanze; Stewardson, Kristin; Workman, J Noah; Zalzala, Fatma; Zhang, Zhao; Agustí, Bibiana; Allen, Tim; Almássy, Katalin; Amkreutz, Luc; Ash, Abigail; Baillif-Ducros, Christèle; Barclay, Alistair.

Nature ; 601(7894): 588-594, 2022 01.

Artigo Inglês | MEDLINE | ID: mdl-34937049

7.

OpenFold: retraining AlphaFold2 yields new insights into its learning mechanisms and capacity for generalization.

Ahdritz, Gustaf; Bouatta, Nazim; Floristean, Christina; Kadyan, Sachin; Xia, Qinghui; Gerecke, William; O'Donnell, Timothy J; Berenberg, Daniel; Fisk, Ian; Zanichelli, Niccolò; Zhang, Bo; Nowaczynski, Arkadiusz; Wang, Bei; Stepniewska-Dziubinska, Marta M; Zhang, Shang; Ojewole, Adegoke; Guney, Murat Efe; Biderman, Stella; Watkins, Andrew M; Ra, Stephen; Lorenzo, Pablo Ribalta; Nivon, Lucas; Weitzner, Brian; Ban, Yih-En Andrew; Chen, Shiyang; Zhang, Minjia; Li, Conglong; Song, Shuaiwen Leon; He, Yuxiong; Sorger, Peter K; Mostaque, Emad; Zhang, Zhao; Bonneau, Richard; AlQuraishi, Mohammed.

Nat Methods ; 2024 May 14.

Artigo Inglês | MEDLINE | ID: mdl-38744917

8.

UAP56 couples piRNA clusters to the perinuclear transposon silencing machinery.

Zhang, Fan; Wang, Jie; Xu, Jia; Zhang, Zhao; Koppetsch, Birgit S; Schultz, Nadine; Vreven, Thom; Meignin, Carine; Davis, Ilan; Zamore, Phillip D; Weng, Zhiping; Theurkauf, William E.

Cell ; 151(4): 871-884, 2012 Nov 09.

Artigo Inglês | MEDLINE | ID: mdl-23141543

9.

Experimental observation of non-Abelian topological charges and edge states.

Guo, Qinghua; Jiang, Tianshu; Zhang, Ruo-Yang; Zhang, Lei; Zhang, Zhao-Qing; Yang, Biao; Zhang, Shuang; Chan, C T.

Nature ; 594(7862): 195-200, 2021 06.

Artigo Inglês | MEDLINE | ID: mdl-34108697

10.

Genomic insights into the formation of human populations in East Asia.

Wang, Chuan-Chao; Yeh, Hui-Yuan; Popov, Alexander N; Zhang, Hu-Qin; Matsumura, Hirofumi; Sirak, Kendra; Cheronet, Olivia; Kovalev, Alexey; Rohland, Nadin; Kim, Alexander M; Mallick, Swapan; Bernardos, Rebecca; Tumen, Dashtseveg; Zhao, Jing; Liu, Yi-Chang; Liu, Jiun-Yu; Mah, Matthew; Wang, Ke; Zhang, Zhao; Adamski, Nicole; Broomandkhoshbacht, Nasreen; Callan, Kimberly; Candilio, Francesca; Carlson, Kellie Sara Duffett; Culleton, Brendan J; Eccles, Laurie; Freilich, Suzanne; Keating, Denise; Lawson, Ann Marie; Mandl, Kirsten; Michel, Megan; Oppenheimer, Jonas; Özdogan, Kadir Toykan; Stewardson, Kristin; Wen, Shaoqing; Yan, Shi; Zalzala, Fatma; Chuang, Richard; Huang, Ching-Jung; Looh, Hana; Shiung, Chung-Ching; Nikitin, Yuri G; Tabarev, Andrei V; Tishkin, Alexey A; Lin, Song; Sun, Zhou-Yong; Wu, Xiao-Ming; Yang, Tie-Lin; Hu, Xi; Chen, Liang.

Nature ; 591(7850): 413-419, 2021 03.

Artigo Inglês | MEDLINE | ID: mdl-33618348

11.

A Non-canonical Role of YAP/TEAD Is Required for Activation of Estrogen-Regulated Enhancers in Breast Cancer.

Zhu, Chi; Li, Li; Zhang, Zhao; Bi, Mingjun; Wang, Hu; Su, Wenyue; Hernandez, Karen; Liu, Pingping; Chen, Junqiang; Chen, Mingqiu; Huang, Tim Hui-Ming; Chen, Lizhen; Liu, Zhijie.

Mol Cell ; 75(4): 791-806.e8, 2019 08 22.

Artigo Inglês | MEDLINE | ID: mdl-31303470

12.

Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function.

Wan, Lixin; Xu, Kexin; Wei, Yongkun; Zhang, Jinfang; Han, Tao; Fry, Christopher; Zhang, Zhao; Wang, Yao Vickie; Huang, Liyu; Yuan, Min; Xia, Weiya; Chang, Wei-Chao; Huang, Wen-Chien; Liu, Chien-Liang; Chang, Yuan-Ching; Liu, Jinsong; Wu, Yun; Jin, Victor X; Dai, Xiangpeng; Guo, Jianfeng; Liu, Jia; Jiang, Shulong; Li, Jin; Asara, John M; Brown, Myles; Hung, Mien-Chie; Wei, Wenyi.

Mol Cell ; 69(2): 279-291.e5, 2018 01 18.

Artigo Inglês | MEDLINE | ID: mdl-29351847

13.

Fluorogenic DNA-PAINT for faster, low-background super-resolution imaging.

Chung, Kenny K H; Zhang, Zhao; Kidd, Phylicia; Zhang, Yongdeng; Williams, Nathan D; Rollins, Bennett; Yang, Yang; Lin, Chenxiang; Baddeley, David; Bewersdorf, Joerg.

Nat Methods ; 19(5): 554-559, 2022 05.

Artigo Inglês | MEDLINE | ID: mdl-35501386

14.

MATR3-antisense LINE1 RNA meshwork scaffolds higher-order chromatin organization.

Zhang, Yuwen; Cao, Xuan; Gao, Zehua; Ma, Xuying; Wang, Qianfeng; Xu, Xiaoxuan; Cai, Xiumei; Zhang, Yan; Zhang, Zhao; Wei, Gang; Wen, Bo.

EMBO Rep ; 24(8): e57550, 2023 08 03.

Artigo Inglês | MEDLINE | ID: mdl-37381832

15.

Colossal barocaloric effects in plastic crystals.

Li, Bing; Kawakita, Yukinobu; Ohira-Kawamura, Seiko; Sugahara, Takeshi; Wang, Hui; Wang, Jingfan; Chen, Yanna; Kawaguchi, Saori I; Kawaguchi, Shogo; Ohara, Koji; Li, Kuo; Yu, Dehong; Mole, Richard; Hattori, Takanori; Kikuchi, Tatsuya; Yano, Shin-Ichiro; Zhang, Zhao; Zhang, Zhe; Ren, Weijun; Lin, Shangchao; Sakata, Osami; Nakajima, Kenji; Zhang, Zhidong.

Nature ; 567(7749): 506-510, 2019 03.

Artigo Inglês | MEDLINE | ID: mdl-30918372

16.

Visual pigment-deficient cones survive and mediate visual signaling despite the lack of outer segments.

Xu, Hui; Jin, Nange; Chuang, Jen-Zen; Zhang, Zhao; Zhong, Xiaoyue; Zhang, Zhijing; Sung, Ching-Hwa; Ribelayga, Christophe P; Fu, Yingbin.

Proc Natl Acad Sci U S A ; 119(9)2022 03 01.

Artigo Inglês | MEDLINE | ID: mdl-35197287

17.

Inhibition of EZH2 transactivation function sensitizes solid tumors to genotoxic stress.

Liao, Yiji; Chen, Chen-Hao; Xiao, Tengfei; de la Peña Avalos, Bárbara; Dray, Eloise V; Cai, Changmeng; Gao, Shuai; Shah, Neel; Zhang, Zhao; Feit, Avery; Xue, Pengya; Liu, Zhijie; Yang, Mei; Lee, Ji Hoon; Xu, Han; Li, Wei; Mei, Shenglin; Pierre, Roodolph S; Shu, Shaokun; Fei, Teng; Duarte, Melissa; Zhao, Jin; Bradner, James E; Polyak, Kornelia; Kantoff, Philip W; Long, Henry; Balk, Steven P; Liu, X Shirley; Brown, Myles; Xu, Kexin.

Proc Natl Acad Sci U S A ; 119(3)2022 01 18.

Artigo Inglês | MEDLINE | ID: mdl-35031563

18.

Bergamot essential oil improves CUMS-induced depression-like behaviour in rats by protecting the plasticity of hippocampal neurons.

Chang, Jun; Yang, Huimin; Shan, Xiaoqian; Zhao, Lan; Li, Yujiao; Zhang, Zhao; Abankwah, Joseph Kofi; Zhang, Mingxing; Bian, Yuhong; Guo, Yi.

J Cell Mol Med ; 28(8): e18178, 2024 Apr.

Artigo Inglês | MEDLINE | ID: mdl-38553964

19.

Integrated metabolome, full-length sequencing, and transcriptome analyses unveil the molecular mechanisms of color formation of the canary yellow and red bracts of Bougainvillea × buttiana 'Chitra'.

Kang, Yuqian; Li, Yuxin; Zhang, Tingting; Wang, Peng; Liu, Wen; Zhang, Zhao; Yu, Wengang; Wang, Jian; Wang, Jian; Zhou, Yang.

Plant J ; 116(5): 1441-1461, 2023 Dec.

Artigo Inglês | MEDLINE | ID: mdl-37648415

20.

Castration alters the ileum microbiota of Holstein bulls and promotes beef flavor compounds.

Shi, Jinping; Li, Zemin; Jia, Li; Ma, Yue; Huang, Yongliang; He, Pengjia; Ran, Tao; Liu, Wangjing; Zhang, Wangdong; Cheng, Qiang; Zhang, Zhao; Lei, Zhaomin.

BMC Genomics ; 25(1): 426, 2024 Apr 29.

Artigo Inglês | MEDLINE | ID: mdl-38684965

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