[Immunosuppressive properties of the influenza virus]. / Immunosuppressivnye svoistva virusa grippa.

In experimental influenza infection in mice, inhibition of generation of antibody and antibody-producing cells was observed against reduced activity of T-suppressors and activation of T-helpers. These data indicate that the immunosuppressive effect of influenza virus is associated with inhibition of some other elements in the lymphocyte T-system rather than T-helpers.

[The development of protracted pneumonias in patients with a history of influenza and acute respiratory diseases]. / Razvitie zatiazhnykh pnevmonii u bol'nykh, perenesshikh gripp i ostrye respiratornye zabolevaniia.

A study is presented of 582 patients with acute viral-bacterial pneumonia in those with a history of influenza and acute respiratory disease (ARD). Protracted course of the disease was observed in 121 (20.8%) and 461 (79.2%) the course of pneumonia was acute. It is shown that the formation of protracted of acute pneumonia in patients with influenza and ARD is furthered by several factors: age, foci of chronic infection, a history of inflammation, increased level of circulating immune complexes, late hospitalization and inadequate therapy. Experiments on Syrian hamsters with induced parainfluenzal infection showed that mixed viral-bacterial infection is more severe than monoinfection.