Detalhe da pesquisa
1.
Causal discovery approach with reinforcement learning for risk factors of type II diabetes mellitus.
BMC Bioinformatics
; 24(1): 296, 2023 Jul 21.
Artigo
Inglês
| MEDLINE | ID: mdl-37480046
2.
Late-Stage Functionalization for the Divergent Synthesis of Podophyllotoxin Derivatives by Rhodium Catalysis.
Chemistry
; 29(43): e202300960, 2023 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37070241
3.
Late-Stage Functionalization for the Divergent Synthesis of Podophyllotoxin Derivatives by Rhodium Catalysis.
Chemistry
; : e202301878, 2023 Jul 03.
Artigo
Inglês
| MEDLINE | ID: mdl-37395436
4.
A Discrete 3d-4f Metallacage as an Efficient Catalytic Nanoreactor for a Three-Component Aza-Darzens Reaction.
Inorg Chem
; 61(9): 4009-4017, 2022 Mar 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35188386
5.
Steric Enforcement of cis-Epoxide Formation in the Radical C-O-Coupling Reaction by Which (S)-2-Hydroxypropylphosphonate Epoxidase (HppE) Produces Fosfomycin.
J Am Chem Soc
; 141(51): 20397-20406, 2019 12 26.
Artigo
Inglês
| MEDLINE | ID: mdl-31769979
6.
Recyclable and Stable α-Methylproline-Derived Chiral Ligands for the Chemical Dynamic Kinetic Resolution of free C,N-Unprotected α-Amino Acids.
Molecules
; 24(12)2019 Jun 13.
Artigo
Inglês
| MEDLINE | ID: mdl-31200582
7.
Stereochemical and Mechanistic Investigation of the Reaction Catalyzed by Fom3 from Streptomyces fradiae, a Cobalamin-Dependent Radical S-Adenosylmethionine Methylase.
Biochemistry
; 57(33): 4972-4984, 2018 08 21.
Artigo
Inglês
| MEDLINE | ID: mdl-30036047
8.
Chemical Resolution of C, N-Unprotected α-Substituted ß-Amino Acids Using Stable and Recyclable Proline-Derived Chiral Ligands.
J Org Chem
; 83(17): 9870-9878, 2018 09 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30004225
9.
Design, synthesis, and structure-activity relationships of novel 4,7,12,12a-tetrahydro-5H-thieno[3',2':3,4]pyrido[1,2-b]isoquinoline and 5,8,12,12a-tetrahydro-6H-thieno[2',3':4,5]pyrido[2,1-a]isoquinoline derivatives as cellular activators of adenosine 5'-monophosphate-activated protein kinase (AMPK).
Bioorg Med Chem
; 26(8): 2017-2027, 2018 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29545016
10.
Purely Chemical Approach for Preparation of d-α-Amino Acids via (S)-to-(R)-Interconversion of Unprotected Tailor-Made α-Amino Acids.
J Org Chem
; 81(9): 3501-8, 2016 05 06.
Artigo
Inglês
| MEDLINE | ID: mdl-27053152
11.
[Lead compound optimization strategy(5) reducing the hERG cardiac toxicity in drug development].
Yao Xue Xue Bao
; 51(10): 1530-9, 2016 10.
Artigo
Chinês
| MEDLINE | ID: mdl-29932317
12.
Asymmetric Synthesis of (2S,3S)-α-(1-Oxoisoindolin-3-yl)glycines under Low-Basicity "Kinetic" Control.
J Org Chem
; 80(22): 11275-80, 2015 Nov 20.
Artigo
Inglês
| MEDLINE | ID: mdl-26523334
13.
Chemical Dynamic Thermodynamic Resolution and S/R Interconversion of Unprotected Unnatural Tailor-made α-Amino Acids.
J Org Chem
; 80(20): 9817-30, 2015 Oct 16.
Artigo
Inglês
| MEDLINE | ID: mdl-26352915
14.
Recyclable Ligands for the Non-Enzymatic Dynamic Kinetic Resolution of Challenging α-Amino Acids.
Angew Chem Int Ed Engl
; 54(44): 12918-22, 2015 Oct 26.
Artigo
Inglês
| MEDLINE | ID: mdl-26367134
15.
The facile construction of the phthalazin-1(2H)-one scaffold via copper-mediated C-H(sp(2))/C-H(sp) coupling under mild conditions.
Beilstein J Org Chem
; 11: 1624-31, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-26664581
16.
Asymmetric synthesis of chiral heterocyclic amino acids via the alkylation of the Ni(II) complex of glycine and alkyl halides.
J Org Chem
; 79(17): 7872-9, 2014 Sep 05.
Artigo
Inglês
| MEDLINE | ID: mdl-25121412
17.
Design, synthesis and evaluation of benzo[a]thieno[3,2-g]quinolizines as novel l-SPD derivatives possessing dopamine D1, D2 and serotonin 5-HT1A multiple action profiles.
Bioorg Med Chem
; 22(21): 5838-46, 2014 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25308766
18.
Chemical kinetic resolution of unprotected ß-substituted ß-amino acids using recyclable chiral ligands.
Angew Chem Int Ed Engl
; 53(30): 7883-6, 2014 Jul 21.
Artigo
Inglês
| MEDLINE | ID: mdl-24917560
19.
Electrochemical oxidative cyclization of N-allylamides for the synthesis of CF3-containing benzoxazines and oxazolines.
RSC Adv
; 14(1): 154-159, 2024 Jan 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38173567
20.
Enantioselective synthesis of 2-substitued-tetrahydroisoquinolin-1-yl glycine derivatives via oxidative cross-dehydrogenative coupling of tertiary amines and chiral nickel(II) glycinate.
J Org Chem
; 78(22): 11204-12, 2013 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24111642