Detalhe da pesquisa
1.
Concurrent tau pathologies in frontotemporal lobar degeneration with TDP-43 pathology.
Neuropathol Appl Neurobiol
; 48(2): e12778, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34823271
2.
Loss of Tmem106b exacerbates FTLD pathologies and causes motor deficits in progranulin-deficient mice.
EMBO Rep
; 21(10): e50197, 2020 10 05.
Artigo
Inglês
| MEDLINE | ID: mdl-32761777
3.
Machine learning-based decision tree classifier for the diagnosis of progressive supranuclear palsy and corticobasal degeneration.
Neuropathol Appl Neurobiol
; 47(7): 931-941, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33763863
4.
A role of the frontotemporal lobar degeneration risk factor TMEM106B in myelination.
Brain
; 143(7): 2255-2271, 2020 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32572497
5.
Loss of TMEM106B leads to myelination deficits: implications for frontotemporal dementia treatment strategies.
Brain
; 143(6): 1905-1919, 2020 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32504082
6.
Lysosomal Dysfunction and Other Pathomechanisms in FTLD: Evidence from Progranulin Genetics and Biology.
Adv Exp Med Biol
; 1281: 219-242, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33433878
7.
The interaction between progranulin and prosaposin is mediated by granulins and the linker region between saposin B and C.
J Neurochem
; 143(2): 236-243, 2017 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28640985
8.
Regulated intramembrane proteolysis of the frontotemporal lobar degeneration risk factor, TMEM106B, by signal peptide peptidase-like 2a (SPPL2a).
J Biol Chem
; 289(28): 19670-80, 2014 Jul 11.
Artigo
Inglês
| MEDLINE | ID: mdl-24872421
9.
TGFß1 inhibits IFNγ-mediated microglia activation and protects mDA neurons from IFNγ-driven neurotoxicity.
J Neurochem
; 134(1): 125-34, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-25827682
10.
Spatially resolved transcriptome of the aging mouse brain.
Aging Cell
; 23(5): e14109, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38372175
11.
Endogenous transforming growth factor-beta promotes quiescence of primary microglia in vitro.
Glia
; 61(2): 287-300, 2013 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-23065670
12.
TMEM106B and myelination: rare leukodystrophy families reveal unexpected connections.
Brain
; 140(12): 3069-3080, 2017 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29194508
13.
Silibinin Prevents TGFß-Induced EMT of RPE in Proliferative Vitreoretinopathy by Inhibiting Stat3 and Smad3 Phosphorylation.
Invest Ophthalmol Vis Sci
; 64(13): 47, 2023 10 03.
Artigo
Inglês
| MEDLINE | ID: mdl-37906058
14.
TGFß signalling plays an important role in IL4-induced alternative activation of microglia.
J Neuroinflammation
; 9: 210, 2012 Sep 04.
Artigo
Inglês
| MEDLINE | ID: mdl-22947253
15.
Regulation of cathepsin D activity by the FTLD protein progranulin.
Acta Neuropathol
; 134(1): 151-153, 2017 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28493053
16.
Regulation of lysosomal trafficking of progranulin by sortilin and prosaposin.
Brain Commun
; 4(1): fcab310, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35169707
17.
Application of team-based learning to ophthalmology in China.
Front Public Health
; 10: 922325, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36299748
18.
Macrophages acquire fibroblast characteristics in a rat model of proliferative vitreoretinopathy.
Ophthalmic Res
; 45(4): 180-90, 2011.
Artigo
Inglês
| MEDLINE | ID: mdl-21051916
19.
Loss of Tmem106b leads to cerebellum Purkinje cell death and motor deficits.
Brain Pathol
; 31(3): e12945, 2021 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33709463
20.
Progranulin deficiency leads to reduced glucocerebrosidase activity.
PLoS One
; 14(7): e0212382, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31291241