Detalhe da pesquisa
1.
Discovery of Small Molecule Drugs Targeting the Biogenesis of microRNA-155 for the Treatment of Systemic Lupus Erythematosus.
Chimia (Aarau)
; 74(10): 798-802, 2020 Oct 28.
Artigo
Inglês
| MEDLINE | ID: mdl-33115563
2.
Conformationally locked lanthanide chelating tags for convenient pseudocontact shift protein nuclear magnetic resonance spectroscopy.
J Biomol NMR
; 72(1-2): 29-38, 2018 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-30117038
3.
Blocking metabotropic glutamate receptor subtype 7 (mGlu7) via the Venus flytrap domain (VFTD) inhibits amygdala plasticity, stress, and anxiety-related behavior.
J Biol Chem
; 289(16): 10975-10987, 2014 Apr 18.
Artigo
Inglês
| MEDLINE | ID: mdl-24596089
4.
Dialdehydes lead to exceptionally fast bioconjugations at neutral pH by virtue of a cyclic intermediate.
Angew Chem Int Ed Engl
; 53(41): 10928-31, 2014 Oct 06.
Artigo
Inglês
| MEDLINE | ID: mdl-25164607
5.
Inducing axial chirality in a "Geländer" oligomer by length mismatch of the oligomer strands.
Angew Chem Int Ed Engl
; 53(52): 14587-91, 2014 Dec 22.
Artigo
Inglês
| MEDLINE | ID: mdl-25367838
6.
Discovery of novel indolinone-based, potent, selective and brain penetrant inhibitors of LRRK2.
Bioorg Med Chem Lett
; 23(14): 4085-90, 2013 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23768909
7.
Modulation of Host-Parasite Interactions with Small Molecules Targeting Schistosoma mansoni microRNAs.
ACS Infect Dis
; 8(10): 2028-2034, 2022 10 14.
Artigo
Inglês
| MEDLINE | ID: mdl-36098656
8.
Anti-cancer activity of 5-O-alkyl 1,4-imino-1,4-dideoxyribitols.
Bioorg Med Chem
; 19(24): 7720-7, 2011 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22079865
9.
Localization of ligands within human carbonic anhydrase II using 19F pseudocontact shift analysis.
Chem Sci
; 10(19): 5064-5072, 2019 May 21.
Artigo
Inglês
| MEDLINE | ID: mdl-31183057
10.
Model-free extraction of spin label position distributions from pseudocontact shift data.
Chem Sci
; 8(4): 2751-2757, 2017 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28553510
11.
Identification and biological characterization of 6-aryl-7-isopropylquinazolinones as novel TRPV1 antagonists that are effective in models of chronic pain.
J Med Chem
; 49(2): 471-4, 2006 Jan 26.
Artigo
Inglês
| MEDLINE | ID: mdl-16420034
12.
Gd(III) complexes for electron-electron dipolar spectroscopy: Effects of deuteration, pH and zero field splitting.
J Magn Reson
; 259: 163-73, 2015 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-26342680
13.
Cyclophilin D as a drug target.
Curr Med Chem
; 10(16): 1485-506, 2003 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-12871122
14.
Discovery of a potent and selective protein kinase CK2 inhibitor by high-throughput docking.
J Med Chem
; 46(13): 2656-62, 2003 Jun 19.
Artigo
Inglês
| MEDLINE | ID: mdl-12801229
15.
Catalytic carbene transfer allows the direct customization of cyclic purine dinucleotides.
Chem Commun (Camb)
; 50(62): 8499-502, 2014 Aug 11.
Artigo
Inglês
| MEDLINE | ID: mdl-24946836