Pesquisa | Secretaria de Estado da Saúde

1.

Increased Ripk1-mediated bone marrow necroptosis leads to myelodysplasia and bone marrow failure in mice.

Wagner, Patrice N; Shi, Qiong; Salisbury-Ruf, Christi T; Zou, Jing; Savona, Michael R; Fedoriw, Yuri; Zinkel, Sandra S.

Blood ; 133(2): 107-120, 2019 01 10.

Artigo Inglês | MEDLINE | ID: mdl-30413413

2.

Revisiting the case for genetically engineered mouse models in human myelodysplastic syndrome research.

Zhou, Ting; Kinney, Marsha C; Scott, Linda M; Zinkel, Sandra S; Rebel, Vivienne I.

Blood ; 126(9): 1057-68, 2015 Aug 27.

Artigo Inglês | MEDLINE | ID: mdl-26077396

3.

MTG16 contributes to colonic epithelial integrity in experimental colitis.

Williams, Christopher S; Bradley, Amber M; Chaturvedi, Rupesh; Singh, Kshipra; Piazuelo, Maria B; Chen, Xi; McDonough, Elizabeth M; Schwartz, David A; Brown, Caroline T; Allaman, Margaret M; Coburn, Lori A; Horst, Sara N; Beaulieu, Dawn B; Choksi, Yash A; Washington, Mary Kay; Williams, Amanda D; Fisher, Melissa A; Zinkel, Sandra S; Peek, Richard M; Wilson, Keith T; Hiebert, Scott W.

Gut ; 62(10): 1446-55, 2013 Oct.

Artigo Inglês | MEDLINE | ID: mdl-22833394

4.

The broad impact of cell death genes on the human disease phenome.

Rich, Abigail L; Lin, Phillip; Gamazon, Eric R; Zinkel, Sandra S.

Cell Death Dis ; 15(4): 251, 2024 Apr 08.

Artigo Inglês | MEDLINE | ID: mdl-38589365

5.

Acetaminophen inhibits cytochrome c redox cycling induced lipid peroxidation.

Yin, Huiyong; Vergeade, Aurélia; Shi, Qiong; Zackert, William E; Gruenberg, Katherine C; Bokiej, Magdalena; Amin, Taneem; Ying, Weizhen; Masterson, Tina S; Zinkel, Sandra S; Oates, John A; Boutaud, Olivier; Roberts, L Jackson.

Biochem Biophys Res Commun ; 423(2): 224-8, 2012 Jun 29.

Artigo Inglês | MEDLINE | ID: mdl-22634010

6.

Bid regulates the pathogenesis of neurotropic reovirus.

Danthi, Pranav; Pruijssers, Andrea J; Berger, Angela K; Holm, Geoffrey H; Zinkel, Sandra S; Dermody, Terence S.

PLoS Pathog ; 6: e1000980, 2010 Jul 01.

Artigo Inglês | MEDLINE | ID: mdl-20617182

7.

Programmed necroptosis is upregulated in low-grade myelodysplastic syndromes and may play a role in the pathogenesis.

Zou, Jing; Shi, Qiong; Chen, Heidi; Juskevicius, Ridas; Zinkel, Sandra S.

Exp Hematol ; 103: 60-72.e5, 2021 11.

Artigo Inglês | MEDLINE | ID: mdl-34563605

8.

Bid maintains mitochondrial cristae structure and function and protects against cardiac disease in an integrative genomics study.

Salisbury-Ruf, Christi T; Bertram, Clinton C; Vergeade, Aurelia; Lark, Daniel S; Shi, Qiong; Heberling, Marlene L; Fortune, Niki L; Okoye, G Donald; Jerome, W Gray; Wells, Quinn S; Fessel, Josh; Moslehi, Javid; Chen, Heidi; Roberts, L Jackson; Boutaud, Olivier; Gamazon, Eric R; Zinkel, Sandra S.

Elife ; 72018 10 03.

Artigo Inglês | MEDLINE | ID: mdl-30281024

9.

Cardiolipin fatty acid remodeling regulates mitochondrial function by modifying the electron entry point in the respiratory chain.

Vergeade, Aurelia; Bertram, Clinton C; Bikineyeva, Alfiya T; Zackert, William E; Zinkel, Sandra S; May, James M; Dikalov, Sergey I; Roberts, L Jackson; Boutaud, Olivier.

Mitochondrion ; 28: 88-95, 2016 05.

Artigo Inglês | MEDLINE | ID: mdl-27085476

10.

In aged mice, low surrogate light chain promotes pro-B-cell apoptotic resistance, compromises the PreBCR checkpoint, and favors generation of autoreactive, phosphorylcholine-specific B cells.

Ratliff, Michelle; Alter, Sarah; McAvoy, Kelly; Frasca, Daniela; Wright, Jacqueline A; Zinkel, Sandra S; Khan, Wasif N; Blomberg, Bonnie B; Riley, Richard L.

Aging Cell ; 14(3): 382-90, 2015 Jun.

Artigo Inglês | MEDLINE | ID: mdl-25727904

11.

BID binds to replication protein A and stimulates ATR function following replicative stress.

Liu, Yang; Vaithiyalingam, Sivaraja; Shi, Qiong; Chazin, Walter J; Zinkel, Sandra S.

Mol Cell Biol ; 31(21): 4298-309, 2011 Nov.

Artigo Inglês | MEDLINE | ID: mdl-21859891

12.

Investigation of the proapoptotic BCL-2 family member bid on the crossroad of the DNA damage response and apoptosis.

Zinkel, Sandra S.

Methods Enzymol ; 442: 231-50, 2008.

Artigo Inglês | MEDLINE | ID: mdl-18662573

13.

A role for proapoptotic BID in the DNA-damage response.

Zinkel, Sandra S; Hurov, Kristen E; Ong, Christy; Abtahi, Farvardean M; Gross, Atan; Korsmeyer, Stanley J.

Cell ; 122(4): 579-91, 2005 Aug 26.

Artigo Inglês | MEDLINE | ID: mdl-16122425

14.

Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease.

Wang, Jing; Iwasaki, Hiromi; Krivtsov, Andrei; Febbo, Phillip G; Thorner, Aaron R; Ernst, Patricia; Anastasiadou, Ema; Kutok, Jeffery L; Kogan, Scott C; Zinkel, Sandra S; Fisher, Jill K; Hess, Jay L; Golub, Todd R; Armstrong, Scott A; Akashi, Koichi; Korsmeyer, Stanley J.

EMBO J ; 24(2): 368-81, 2005 Jan 26.

Artigo Inglês | MEDLINE | ID: mdl-15635450

15.

Proapoptotic BID is required for myeloid homeostasis and tumor suppression.

Zinkel, Sandra S; Ong, Christy C; Ferguson, David O; Iwasaki, Hiromi; Akashi, Koichi; Bronson, Roderick T; Kutok, Jeffery L; Alt, Frederick W; Korsmeyer, Stanley J.

Genes Dev ; 17(2): 229-39, 2003 Jan 15.

Artigo Inglês | MEDLINE | ID: mdl-12533511

16.

Bid plays a role in the DNA damage response.

Zinkel, Sandra S; Hurov, Kristen E; Gross, Atan.

Cell ; 130(1): 9-10; author reply 10-1, 2007 Jul 13.

Artigo Inglês | MEDLINE | ID: mdl-17632047

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