Detalhe da pesquisa
1.
Repurposing of 5-nitrofuran-3,5-disubstituted isoxazoles: A thriving scaffold to antitrypanosomal agents.
Arch Pharm (Weinheim)
; 356(4): e2200472, 2023 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-36534890
2.
Synthesis, antitumor activity and in silico analyses of amino acid derivatives of artepillin C, drupanin and baccharin from green propolis.
Bioorg Med Chem
; 47: 116372, 2021 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34454129
3.
Trypanocidal activity of new 1,6-diphenyl-1H-pyrazolo[3,4-b]pyridine derivatives: Synthesis, in vitro and in vivo studies.
Bioorg Med Chem
; 29: 115855, 2021 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33199200
4.
Melatonin decreases circulating Trypanosoma cruzi load with no effect on tissue parasite replication.
Can J Physiol Pharmacol
; 99(8): 795-802, 2021 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-33296274
5.
Dipeptidyl nitrile derivatives suppress the Trypanosoma cruzi in vitro infection.
Exp Parasitol
; 219: 108032, 2020 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-33137308
6.
Effect of Fluorination on the Structure and Anti-Trypanosoma cruzy Activity of Oxorhenium(V) Complexes with S,N,S-Tridentate Thiosemicarbazones and Benzoylthioureas. Synthesis and Structures of Technetium(V) Analogues.
Inorg Chem
; 58(15): 10129-10138, 2019 Aug 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31310108
7.
Dipeptidyl nitrile derivatives have cytostatic effects against Leishmania spp. promastigotes.
Exp Parasitol
; 200: 84-91, 2019 May.
Artigo
Inglês
| MEDLINE | ID: mdl-30954455
8.
Benefits of Ascorbic Acid in Association with Low-Dose Benznidazole in Treatment of Chagas Disease.
Antimicrob Agents Chemother
; 62(9)2018 09.
Artigo
Inglês
| MEDLINE | ID: mdl-29987143
9.
Development and Evaluation of a Nanoemulsion Containing Ursolic Acid: a Promising Trypanocidal Agent : Nanoemulsion with Ursolic Acid Against T. cruzi.
AAPS PharmSciTech
; 18(7): 2551-2560, 2017 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-28224391
10.
Novel naphthoquinone derivatives and evaluation of their trypanocidal and leishmanicidal activities.
Org Biomol Chem
; 13(2): 428-37, 2015 Jan 14.
Artigo
Inglês
| MEDLINE | ID: mdl-25370790
11.
Interaction between diterpene icetexanes and old yellow enzymes of Leishmania braziliensis and Trypanosoma cruzi.
Int J Biol Macromol
; 259(Pt 2): 129192, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38216013
12.
Design and Synthesis of Novel 3-Nitro-1H-1,2,4-triazole-1,2,3-triazole-1,4-disubstituted Analogs as Promising Antitrypanosomatid Agents: Evaluation of In Vitro Activity against Chagas Disease and Leishmaniasis.
J Med Chem
; 67(4): 2584-2601, 2024 Feb 22.
Artigo
Inglês
| MEDLINE | ID: mdl-38305199
13.
In vivo activity of ursolic and oleanolic acids during the acute phase of Trypanosoma cruzi infection.
Exp Parasitol
; 134(4): 455-9, 2013 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-23648663
14.
Evaluation of the in vivo therapeutic properties of (-)-cubebin and (-)-hinokinin against Trypanosoma cruzi.
Exp Parasitol
; 133(4): 442-6, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23274812
15.
In vivo infection by Trypanosoma cruzi: a morphometric study of tissue changes in mice.
Parasitol Res
; 112(1): 431-6, 2013 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-22837101
16.
Ligand-based virtual screening, molecular dynamics, and biological evaluation of repurposed drugs as inhibitors of Trypanosoma cruzi proteasome.
J Biomol Struct Dyn
; 41(23): 13844-13856, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36826433
17.
Novel synthetic derivatives of cinnamic and p-coumaric acids with antiproliferative effect on breast MCF-7 tumor cells.
Nat Prod Res
; 37(24): 4210-4220, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36799539
18.
Trypanosoma cruzi Sirtuin 2 as a Relevant Druggable Target: New Inhibitors Developed by Computer-Aided Drug Design.
Pharmaceuticals (Basel)
; 16(3)2023 Mar 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36986527
19.
Design, synthesis and antitrypanosomatid activity of 2-nitroimidazole-3,5-disubstituted isoxazole compounds based on benznidazole.
Eur J Med Chem
; 260: 115451, 2023 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37573209
20.
In vitro metabolism of grandisin, a lignan with anti-chagasic activity.
Planta Med
; 78(18): 1939-41, 2012 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-23150073