RESUMO
Pituitary enlargement can occur in primary hypothyroidism. Pituitary volume determination in 20 cases of primary hypothyroidism showed pituitary fossa enlargement in 25% of the patients, with close correlation to highest serum thyrotropin (TSH) levels. Normalization of TSH serum levels should prevent hypertrophy of the thyrotropic cells.
Assuntos
Hipotireoidismo/complicações , Doenças da Hipófise/complicações , Adolescente , Adulto , Idoso , Criança , Feminino , Humanos , Hipertrofia , Pessoa de Meia-Idade , Sela Túrcica/patologia , Tireotropina/sangue , Tiroxina/sangueRESUMO
Pyridoxine has been reported as having an antilactogenic effect, presumably by suppressing prolactin secretion. We have measured serum prolactin levels during pyridoxine administration in two groups of hyperprolactinaemic subjects. In normal postpartum women, the postdelivery fall in serum prolactin levels did not differ significantly in treated and control subjects. In patients with chlorpromazine-induced hyperprolactinaemia and galactorrhoea, pyridoxine did not reduce the elevated levels. In neither group was milk production suppressed.