Detalhe da pesquisa
1.
A unifying structural and functional model of the coronavirus replication organelle: Tracking down RNA synthesis.
PLoS Biol
; 18(6): e3000715, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32511245
2.
Adaptive Mutations in Replicase Transmembrane Subunits Can Counteract Inhibition of Equine Arteritis Virus RNA Synthesis by Cyclophilin Inhibitors.
J Virol
; 93(18)2019 09 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31243130
3.
Host Factors in Coronavirus Replication.
Curr Top Microbiol Immunol
; 419: 1-42, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-28643204
4.
A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins.
J Virol
; 89(16): 8318-33, 2015 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-26041291
5.
Design, synthesis and evaluation of a series of acyclic fleximer nucleoside analogues with anti-coronavirus activity.
Bioorg Med Chem Lett
; 25(15): 2923-6, 2015 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26048809
6.
Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture.
Antimicrob Agents Chemother
; 58(8): 4875-84, 2014 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-24841269
7.
Cyclophilin inhibitors block arterivirus replication by interfering with viral RNA synthesis.
J Virol
; 87(3): 1454-64, 2013 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-23152531
8.
MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment.
J Gen Virol
; 94(Pt 8): 1749-1760, 2013 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-23620378
9.
Cyclosporin A inhibits the replication of diverse coronaviruses.
J Gen Virol
; 92(Pt 11): 2542-2548, 2011 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-21752960
10.
Immunogenicity and efficacy of one and two doses of Ad26.COV2.S COVID vaccine in adult and aged NHP.
J Exp Med
; 218(7)2021 07 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33909009
11.
Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses.
NPJ Vaccines
; 5: 91, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-33083026
12.
Cyclophilins and cyclophilin inhibitors in nidovirus replication.
Virology
; 522: 46-55, 2018 09.
Artigo
Inglês
| MEDLINE | ID: mdl-30014857
13.
Coronaviruses and arteriviruses display striking differences in their cyclophilin A-dependence during replication in cell culture.
Virology
; 517: 148-156, 2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29249267
14.
Alisporivir inhibits MERS- and SARS-coronavirus replication in cell culture, but not SARS-coronavirus infection in a mouse model.
Virus Res
; 228: 7-13, 2017 01 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27840112
15.
The in vitro RNA synthesizing activity of the isolated arterivirus replication/transcription complex is dependent on a host factor.
J Biol Chem
; 283(24): 16525-36, 2008 Jun 13.
Artigo
Inglês
| MEDLINE | ID: mdl-18411274