Detalhe da pesquisa
1.
Personalised modelling of clinical heterogeneity between medium-chain acyl-CoA dehydrogenase patients.
BMC Biol
; 21(1): 184, 2023 09 04.
Artigo
Inglês
| MEDLINE | ID: mdl-37667308
2.
The discovAIR project: a roadmap towards the Human Lung Cell Atlas.
Eur Respir J
; 60(2)2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35086829
3.
Impaired Very-Low-Density Lipoprotein catabolism links hypoglycemia to hypertriglyceridemia in Glycogen Storage Disease type Ia.
J Inherit Metab Dis
; 44(4): 879-892, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33739445
4.
The promiscuous enzyme medium-chain 3-keto-acyl-CoA thiolase triggers a vicious cycle in fatty-acid beta-oxidation.
PLoS Comput Biol
; 13(4): e1005461, 2017 04.
Artigo
Inglês
| MEDLINE | ID: mdl-28369071
5.
Living on the edge: substrate competition explains loss of robustness in mitochondrial fatty-acid oxidation disorders.
BMC Biol
; 14(1): 107, 2016 12 07.
Artigo
Inglês
| MEDLINE | ID: mdl-27927213
6.
Translational Targeted Proteomics Profiling of Mitochondrial Energy Metabolic Pathways in Mouse and Human Samples.
J Proteome Res
; 15(9): 3204-13, 2016 09 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27447838
7.
Biochemical competition makes fatty-acid ß-oxidation vulnerable to substrate overload.
PLoS Comput Biol
; 9(8): e1003186, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23966849
8.
The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism.
J Lipid Res
; 54(9): 2325-40, 2013 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-23821742
9.
Gut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids.
Am J Physiol Gastrointest Liver Physiol
; 305(12): G900-10, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-24136789
10.
Testing biochemistry revisited: how in vivo metabolism can be understood from in vitro enzyme kinetics.
PLoS Comput Biol
; 8(4): e1002483, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22570597
11.
Rebalancing of mitochondrial homeostasis through an NAD+-SIRT1 pathway preserves intestinal barrier function in severe malnutrition.
EBioMedicine
; 96: 104809, 2023 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-37738832
12.
Full humanization of the glycolytic pathway in Saccharomyces cerevisiae.
Cell Rep
; 39(13): 111010, 2022 06 28.
Artigo
Inglês
| MEDLINE | ID: mdl-35767960
13.
Metabolic regulation rather than de novo enzyme synthesis dominates the osmo-adaptation of yeast.
Yeast
; 28(1): 43-53, 2011 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-20803479
14.
Systems biochemistry in practice: experimenting with modelling and understanding, with regulation and control.
Biochem Soc Trans
; 38(5): 1189-96, 2010 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-20863282
15.
Systems biology from micro-organisms to human metabolic diseases: the role of detailed kinetic models.
Biochem Soc Trans
; 38(5): 1294-301, 2010 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-20863302
16.
Simultaneous Induction of Glycolysis and Oxidative Phosphorylation during Activation of Hepatic Stellate Cells Reveals Novel Mitochondrial Targets to Treat Liver Fibrosis.
Cells
; 9(11)2020 11 11.
Artigo
Inglês
| MEDLINE | ID: mdl-33187083
17.
Oncogenic ß-catenin and PIK3CA instruct network states and cancer phenotypes in intestinal organoids.
J Cell Biol
; 216(6): 1567-1577, 2017 06 05.
Artigo
Inglês
| MEDLINE | ID: mdl-28442534
18.
A systems study reveals concurrent activation of AMPK and mTOR by amino acids.
Nat Commun
; 7: 13254, 2016 11 21.
Artigo
Inglês
| MEDLINE | ID: mdl-27869123
19.
Molecular mechanisms of mTOR regulation by stress.
Mol Cell Oncol
; 2(2): e970489, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-27308421
20.
Protection against the Metabolic Syndrome by Guar Gum-Derived Short-Chain Fatty Acids Depends on Peroxisome Proliferator-Activated Receptor γ and Glucagon-Like Peptide-1.
PLoS One
; 10(8): e0136364, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-26292284