Detalhe da pesquisa
1.
Low-dose Ad26.COV2.S protection against SARS-CoV-2 challenge in rhesus macaques.
Cell
; 184(13): 3467-3473.e11, 2021 06 24.
Artigo
Inglês
| MEDLINE | ID: mdl-34133941
2.
Quantitative Mass Spectrometry Imaging to Study Drug Distribution in the Intestine Following Oral Dosing.
Anal Chem
; 93(4): 2144-2151, 2021 02 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33470103
3.
Exacerbation of Background Nuclear Cataracts in Sprague-Dawley Rats in Embryo-Fetal Development Studies With JNJ-42165279, a Fatty Acid Amide Hydrolase Inhibitor.
Toxicol Pathol
; 49(6): 1193-1205, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34128434
4.
Cross-Species Molecular Imaging of Bile Salts and Lipids in Liver: Identification of Molecular Structural Markers in Health and Disease.
Anal Chem
; 90(20): 11835-11846, 2018 10 16.
Artigo
Inglês
| MEDLINE | ID: mdl-30232879
5.
Comparison of the Local Tolerability to 5 Long-acting Drug Nanosuspensions with Different Stabilizing Excipients, Following a Single Intramuscular Administration in the Rat.
Toxicol Pathol
; 46(1): 85-100, 2018 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29096596
6.
Translational safety biomarkers of colonic barrier integrity in the rat.
J Appl Toxicol
; 38(10): 1282-1292, 2018 10.
Artigo
Inglês
| MEDLINE | ID: mdl-29781175
7.
Modeling the Time Course of the Tissue Responses to Intramuscular Long-acting Paliperidone Palmitate Nano-/Microcrystals and Polystyrene Microspheres in the Rat.
Toxicol Pathol
; 44(2): 189-210, 2016 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-26698322
8.
Intestinal organoids as an in vitro platform to characterize disposition, metabolism, and safety profile of small molecules.
Eur J Pharm Sci
; 188: 106481, 2023 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37244450
9.
Booster vaccination with Ad26.COV2.S or an Omicron-adapted vaccine in pre-immune hamsters protects against Omicron BA.2.
NPJ Vaccines
; 8(1): 40, 2023 Mar 16.
Artigo
Inglês
| MEDLINE | ID: mdl-36927774
10.
An analysis of pharmaceutical experience with decades of rat carcinogenicity testing: support for a proposal to modify current regulatory guidelines.
Toxicol Pathol
; 39(4): 716-44, 2011 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-21666103
11.
Ad26.COV2.S protects Syrian hamsters against G614 spike variant SARS-CoV-2 and does not enhance respiratory disease.
NPJ Vaccines
; 6(1): 39, 2021 Mar 19.
Artigo
Inglês
| MEDLINE | ID: mdl-33741993
12.
Immunogenicity and efficacy of one and two doses of Ad26.COV2.S COVID vaccine in adult and aged NHP.
J Exp Med
; 218(7)2021 07 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33909009
13.
Testing of acetaminophen in support of the international multilaboratory in vivo rat Pig-a assay validation trial.
Environ Mol Mutagen
; 61(5): 508-525, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32187737
14.
In vitro evaluation of poloxamer in situ forming gels for bedaquiline fumarate salt and pharmacokinetics following intramuscular injection in rats.
Int J Pharm X
; 1: 100016, 2019 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-31517281
15.
The effect of macrophage and angiogenesis inhibition on the drug release and absorption from an intramuscular sustained-release paliperidone palmitate suspension.
J Control Release
; 230: 95-108, 2016 05 28.
Artigo
Inglês
| MEDLINE | ID: mdl-27067365
16.
High-resolution laser ablation-inductively coupled plasma-mass spectrometry imaging of cisplatin-induced nephrotoxic side effects.
Anal Chim Acta
; 945: 23-30, 2016 Nov 16.
Artigo
Inglês
| MEDLINE | ID: mdl-27968712
17.
"All pigs are equal" Does the background data from juvenile Göttingen minipigs support this?
Reprod Toxicol
; 64: 105-15, 2016 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27112527
18.
Mass Spectrometry Imaging of Drug Related Crystal-Like Structures in Formalin-Fixed Frozen and Paraffin-Embedded Rabbit Kidney Tissue Sections.
J Am Soc Mass Spectrom
; 27(1): 117-23, 2016 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-26384683
19.
Juvenile animal testing of hydroxypropyl-ß-cyclodextrin in support of pediatric drug development.
Reprod Toxicol
; 56: 87-96, 2015 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26013174
20.
Multimodal non-linear optical imaging for the investigation of drug nano-/microcrystal-cell interactions.
Eur J Pharm Biopharm
; 96: 338-48, 2015 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-26347923