Detalhe da pesquisa
1.
Model-based dose optimization framework for bedaquiline, pretomanid and linezolid for the treatment of drug-resistant tuberculosis.
Br J Clin Pharmacol
; 90(2): 463-474, 2024 02.
Artigo
Inglês
| MEDLINE | ID: mdl-37817504
2.
Computational neurosciences and quantitative systems pharmacology: a powerful combination for supporting drug development in neurodegenerative diseases.
J Pharmacokinet Pharmacodyn
; 2023 Jul 28.
Artigo
Inglês
| MEDLINE | ID: mdl-37505397
3.
Using a Network-Based Analysis Approach to Investigate the Involvement of S. aureus in the Pathogenesis of Granulomatosis with Polyangiitis.
Int J Mol Sci
; 24(3)2023 Jan 17.
Artigo
Inglês
| MEDLINE | ID: mdl-36768148
4.
Quantitative Systems Pharmacology Modeling Framework of Autophagy in Tuberculosis: Application to Adjunctive Metformin Host-Directed Therapy.
Antimicrob Agents Chemother
; 66(8): e0036622, 2022 08 16.
Artigo
Inglês
| MEDLINE | ID: mdl-35862740
5.
Modelling inflammatory biomarker dynamics in a human lipopolysaccharide (LPS) challenge study using delay differential equations.
Br J Clin Pharmacol
; 88(12): 5420-5427, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-35921300
6.
A Quantitative Systems Pharmacology Perspective on the Importance of Parameter Identifiability.
Bull Math Biol
; 84(3): 39, 2022 02 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35132487
7.
A system pharmacology Boolean network model for the TLR4-mediated inflammatory response in early sepsis.
J Pharmacokinet Pharmacodyn
; 49(6): 645-655, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36261775
8.
Model informed quantification of the feed-forward stimulation of growth hormone by growth hormone-releasing hormone.
Br J Clin Pharmacol
; 86(8): 1575-1584, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32087619
9.
Mathematical Modelling of Alternative Pathway of Complement System.
Bull Math Biol
; 82(2): 33, 2020 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32062771
10.
Quantification of the endogenous growth hormone and prolactin lowering effects of a somatostatin-dopamine chimera using population PK/PD modeling.
J Pharmacokinet Pharmacodyn
; 47(3): 229-239, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32248329
11.
Use of translational modeling and simulation for quantitative comparison of PF-06804103, a new generation HER2 ADC, with Trastuzumab-DM1.
J Pharmacokinet Pharmacodyn
; 47(5): 513-526, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32710210
12.
Mechanistic and Quantitative Understanding of Pharmacokinetics in Zebrafish Larvae through Nanoscale Blood Sampling and Metabolite Modeling of Paracetamol.
J Pharmacol Exp Ther
; 371(1): 15-24, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31371482
13.
How are growth hormone and insulin-like growth factor-1 reported as markers for drug effectiveness in clinical acromegaly research? A comprehensive methodologic review.
Pituitary
; 21(3): 310-322, 2018 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-29605877
14.
Model reduction in mathematical pharmacology : Integration, reduction and linking of PBPK and systems biology models.
J Pharmacokinet Pharmacodyn
; 45(4): 537-555, 2018 08.
Artigo
Inglês
| MEDLINE | ID: mdl-29582349
15.
Correction to: Modelling the delay between pharmacokinetics and EEG effects of morphine in rats: binding kinetic versus effect compartment models.
J Pharmacokinet Pharmacodyn
; 45(5): 763, 2018 10.
Artigo
Inglês
| MEDLINE | ID: mdl-30171443
16.
Modelling the delay between pharmacokinetics and EEG effects of morphine in rats: binding kinetic versus effect compartment models.
J Pharmacokinet Pharmacodyn
; 45(4): 621-635, 2018 08.
Artigo
Inglês
| MEDLINE | ID: mdl-29777407
17.
Methods of Model Reduction for Large-Scale Biological Systems: A Survey of Current Methods and Trends.
Bull Math Biol
; 79(7): 1449-1486, 2017 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-28656491
18.
A mathematical analysis of rebound in a target-mediated drug disposition model: II. With feedback.
J Math Biol
; 75(1): 33-84, 2017 07.
Artigo
Inglês
| MEDLINE | ID: mdl-27832321
19.
A two-step deconvolution-analysis-informed population pharmacodynamic modeling approach for drugs targeting pulsatile endogenous compounds.
J Pharmacokinet Pharmacodyn
; 44(4): 389-400, 2017 08.
Artigo
Inglês
| MEDLINE | ID: mdl-28497294
20.
Pooled population pharmacokinetic model of imipenem in plasma and the lung epithelial lining fluid.
Br J Clin Pharmacol
; 81(6): 1113-23, 2016 06.
Artigo
Inglês
| MEDLINE | ID: mdl-26852277