Pesquisa | Secretaria de Estado da Saúde

1.

Tissue Immunity in the Bladder.

Bowyer, Georgina S; Loudon, Kevin W; Suchanek, Ondrej; Clatworthy, Menna R.

Annu Rev Immunol; 40: 499-523, 2022 04 26.

Artigo Inglês | MEDLINE | ID: mdl-35471839

2.

Distinct microbial and immune niches of the human colon.

James, Kylie R; Gomes, Tomas; Elmentaite, Rasa; Kumar, Nitin; Gulliver, Emily L; King, Hamish W; Stares, Mark D; Bareham, Bethany R; Ferdinand, John R; Petrova, Velislava N; Polanski, Krzysztof; Forster, Samuel C; Jarvis, Lorna B; Suchanek, Ondrej; Howlett, Sarah; James, Louisa K; Jones, Joanne L; Meyer, Kerstin B; Clatworthy, Menna R; Saeb-Parsy, Kourosh; Lawley, Trevor D; Teichmann, Sarah A.

Nat Immunol; 21(3): 343-353, 2020 03.

Artigo Inglês | MEDLINE | ID: mdl-32066951

3.

Dynamic regulation of hypoxia-inducible factor-1α activity is essential for normal B cell development.

Burrows, Natalie; Bashford-Rogers, Rachael J M; Bhute, Vijesh J; Peñalver, Ana; Ferdinand, John R; Stewart, Benjamin J; Smith, Joscelin E G; Deobagkar-Lele, Mukta; Giudice, Girolamo; Connor, Thomas M; Inaba, Akimichi; Bergamaschi, Laura; Smith, Sam; Tran, Maxine G B; Petsalaki, Evangelia; Lyons, Paul A; Espeli, Marion; Huntly, Brian J P; Smith, Kenneth G C; Cornall, Richard J; Clatworthy, Menna R; Maxwell, Patrick H.

Nat Immunol; 21(11): 1408-1420, 2020 11.

Artigo Inglês | MEDLINE | ID: mdl-32868930

4.

The meninges-a cradle and school for nurturing and educating developing B cells.

Clatworthy, Menna R.

Immunity; 54(12): 2688-2690, 2021 12 14.

Artigo Inglês | MEDLINE | ID: mdl-34910935

5.

Reticular Fibroblasts Expressing the Transcription Factor WT1 Define a Stromal Niche that Maintains and Replenishes Splenic Red Pulp Macrophages.

Bellomo, Alicia; Mondor, Isabelle; Spinelli, Lionel; Lagueyrie, Marine; Stewart, Benjamin J; Brouilly, Nicolas; Malissen, Bernard; Clatworthy, Menna R; Bajénoff, Marc.

Immunity; 53(1): 127-142.e7, 2020 07 14.

Artigo Inglês | MEDLINE | ID: mdl-32562599

6.

Author Correction: Dynamic regulation of hypoxia-inducible factor-1α activity is essential for normal B cell development.

Burrows, Natalie; Bashford-Rogers, Rachael J M; Bhute, Vijesh J; Peñalver, Ana; Ferdinand, John R; Stewart, Benjamin J; Smith, Joscelin E G; Deobagkar-Lele, Mukta; Giudice, Girolamo; Connor, Thomas M; Inaba, Akimichi; Bergamaschi, Laura; Smith, Sam; Tran, Maxine G B; Petsalaki, Evangelia; Lyons, Paul A; Espeli, Marion; Huntly, Brian J P; Smith, Kenneth G C; Cornall, Richard J; Clatworthy, Menna R; Maxwell, Patrick H.

Nat Immunol; 22(11): 1465, 2021 Nov.

Artigo Inglês | MEDLINE | ID: mdl-34522040

7.

Local and systemic responses to SARS-CoV-2 infection in children and adults.

Yoshida, Masahiro; Worlock, Kaylee B; Huang, Ni; Lindeboom, Rik G H; Butler, Colin R; Kumasaka, Natsuhiko; Dominguez Conde, Cecilia; Mamanova, Lira; Bolt, Liam; Richardson, Laura; Polanski, Krzysztof; Madissoon, Elo; Barnes, Josephine L; Allen-Hyttinen, Jessica; Kilich, Eliz; Jones, Brendan C; de Wilton, Angus; Wilbrey-Clark, Anna; Sungnak, Waradon; Pett, J Patrick; Weller, Juliane; Prigmore, Elena; Yung, Henry; Mehta, Puja; Saleh, Aarash; Saigal, Anita; Chu, Vivian; Cohen, Jonathan M; Cane, Clare; Iordanidou, Aikaterini; Shibuya, Soichi; Reuschl, Ann-Kathrin; Herczeg, Iván T; Argento, A Christine; Wunderink, Richard G; Smith, Sean B; Poor, Taylor A; Gao, Catherine A; Dematte, Jane E; Reynolds, Gary; Haniffa, Muzlifah; Bowyer, Georgina S; Coates, Matthew; Clatworthy, Menna R; Calero-Nieto, Fernando J; Göttgens, Berthold; O'Callaghan, Christopher; Sebire, Neil J; Jolly, Clare; De Coppi, Paolo.

Nature; 602(7896): 321-327, 2022 02.

Artigo Inglês | MEDLINE | ID: mdl-34937051

8.

Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response.

Mulderrig, Lee; Garaycoechea, Juan I; Tuong, Zewen K; Millington, Christopher L; Dingler, Felix A; Ferdinand, John R; Gaul, Liam; Tadross, John A; Arends, Mark J; O'Rahilly, Stephen; Crossan, Gerry P; Clatworthy, Menna R; Patel, Ketan J.

Nature; 600(7887): 158-163, 2021 12.

Artigo Inglês | MEDLINE | ID: mdl-34819667

9.

Cells of the human intestinal tract mapped across space and time.

Elmentaite, Rasa; Kumasaka, Natsuhiko; Roberts, Kenny; Fleming, Aaron; Dann, Emma; King, Hamish W; Kleshchevnikov, Vitalii; Dabrowska, Monika; Pritchard, Sophie; Bolt, Liam; Vieira, Sara F; Mamanova, Lira; Huang, Ni; Perrone, Francesca; Goh Kai'En, Issac; Lisgo, Steven N; Katan, Matilda; Leonard, Steven; Oliver, Thomas R W; Hook, C Elizabeth; Nayak, Komal; Campos, Lia S; Domínguez Conde, Cecilia; Stephenson, Emily; Engelbert, Justin; Botting, Rachel A; Polanski, Krzysztof; van Dongen, Stijn; Patel, Minal; Morgan, Michael D; Marioni, John C; Bayraktar, Omer Ali; Meyer, Kerstin B; He, Xiaoling; Barker, Roger A; Uhlig, Holm H; Mahbubani, Krishnaa T; Saeb-Parsy, Kourosh; Zilbauer, Matthias; Clatworthy, Menna R; Haniffa, Muzlifah; James, Kylie R; Teichmann, Sarah A.

Nature; 597(7875): 250-255, 2021 09.

Artigo Inglês | MEDLINE | ID: mdl-34497389

10.

Gut-educated IgA plasma cells defend the meningeal venous sinuses.

Fitzpatrick, Zachary; Frazer, Gordon; Ferro, Ashley; Clare, Simon; Bouladoux, Nicolas; Ferdinand, John; Tuong, Zewen Kelvin; Negro-Demontel, Maria Luciana; Kumar, Nitin; Suchanek, Ondrej; Tajsic, Tamara; Harcourt, Katherine; Scott, Kirsten; Bashford-Rogers, Rachel; Helmy, Adel; Reich, Daniel S; Belkaid, Yasmine; Lawley, Trevor D; McGavern, Dorian B; Clatworthy, Menna R.

Nature; 587(7834): 472-476, 2020 11.

Artigo Inglês | MEDLINE | ID: mdl-33149302

11.

Epigenetics and tissue immunity-Translating environmental cues into functional adaptations.

Tuong, Zewen Kelvin; Stewart, Benjamin J; Guo, Shuang Andrew; Clatworthy, Menna R.

Immunol Rev; 305(1): 111-136, 2022 01.

Artigo Inglês | MEDLINE | ID: mdl-34821397

12.

Activation of the hypothalamic-pituitary-adrenal axis by exogenous and endogenous GDF15.

Cimino, Irene; Kim, Hanna; Tung, Y C Loraine; Pedersen, Kent; Rimmington, Debra; Tadross, John A; Kohnke, Sara N; Neves-Costa, Ana; Barros, André; Joaquim, Stephanie; Bennett, Don; Melvin, Audrey; Lockhart, Samuel M; Rostron, Anthony J; Scott, Jonathan; Liu, Hui; Burling, Keith; Barker, Peter; Clatworthy, Menna R; Lee, E-Chiang; Simpson, A John; Yeo, Giles S H; Moita, Luís F; Bence, Kendra K; Jørgensen, Sebastian Beck; Coll, Anthony P; Breen, Danna M; O'Rahilly, Stephen.

Proc Natl Acad Sci U S A; 118(27)2021 07 06.

Artigo Inglês | MEDLINE | ID: mdl-34187898

13.

Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis.

Jing, Chenzhi; Castro-Dopico, Tomas; Richoz, Nathan; Tuong, Zewen K; Ferdinand, John R; Lok, Laurence S C; Loudon, Kevin W; Banham, Gemma D; Mathews, Rebeccah J; Cader, Zaeem; Fitzpatrick, Susan; Bashant, Kathleen R; Kaplan, Mariana J; Kaser, Arthur; Johnson, Randall S; Murphy, Michael P; Siegel, Richard M; Clatworthy, Menna R.

Proc Natl Acad Sci U S A; 117(26): 15160-15171, 2020 06 30.

Artigo Inglês | MEDLINE | ID: mdl-32541026

14.

MicroRNA antagonist therapy during normothermic machine perfusion of donor kidneys.

Thompson, Emily R; Sewpaul, Avinash; Figuereido, Rodrigo; Bates, Lucy; Tingle, Samuel J; Ferdinand, John R; Situmorang, Gerhard R; Ladak, Shameem S; Connelly, Chloe M; Hosgood, Sarah A; Nicholson, Michael L; Clatworthy, Menna R; Ali, Simi; Wilson, Colin H; Sheerin, Neil S.

Am J Transplant; 22(4): 1088-1100, 2022 04.

Artigo Inglês | MEDLINE | ID: mdl-34932895

15.

B cell class switching in intestinal immunity in health and disease.

Fleming, Aaron; Castro-Dopico, Tomas; Clatworthy, Menna R.

Scand J Immunol; 95(2): e13139, 2022 Feb.

Artigo Inglês | MEDLINE | ID: mdl-34978077

16.

B Lymphocyte-Derived CCL7 Augments Neutrophil and Monocyte Recruitment, Exacerbating Acute Kidney Injury.

Inaba, Akimichi; Tuong, Zewen K; Riding, Alexandra M; Mathews, Rebeccah J; Martin, Jack L; Saeb-Parsy, Kourosh; Clatworthy, Menna R.

J Immunol; 205(5): 1376-1384, 2020 09 01.

Artigo Inglês | MEDLINE | ID: mdl-32737150

17.

Renal Sodium Gradient Orchestrates a Dynamic Antibacterial Defense Zone.

Berry, Miriam R; Mathews, Rebeccah J; Ferdinand, John R; Jing, Chenzhi; Loudon, Kevin W; Wlodek, Elizabeth; Dennison, Thomas W; Kuper, Christoph; Neuhofer, Wolfgang; Clatworthy, Menna R.

Cell; 170(5): 860-874.e19, 2017 Aug 24.

Artigo Inglês | MEDLINE | ID: mdl-28803730

18.

Neutrophils in secondary lymphoid organs.

Lok, Laurence S C; Clatworthy, Menna R.

Immunology; 164(4): 677-688, 2021 12.

Artigo Inglês | MEDLINE | ID: mdl-34411302

19.

Cytokine absorption during human kidney perfusion reduces delayed graft function-associated inflammatory gene signature.

Ferdinand, John R; Hosgood, Sarah A; Moore, Tom; Ferro, Ashley; Ward, Christopher J; Castro-Dopico, Tomas; Nicholson, Michael L; Clatworthy, Menna R.

Am J Transplant; 21(6): 2188-2199, 2021 06.

Artigo Inglês | MEDLINE | ID: mdl-33098231

20.

Lysis of cold-storage-induced microvascular obstructions for ex vivo revitalization of marginal human kidneys.

DiRito, Jenna R; Hosgood, Sarah A; Reschke, Melanie; Albert, Claire; Bracaglia, Laura G; Ferdinand, John R; Stewart, Benjamin J; Edwards, Christopher M; Vaish, Anand G; Thiru, Sathia; Mulligan, David C; Haakinson, Danielle J; Clatworthy, Menna R; Saltzman, W Mark; Pober, Jordan S; Nicholson, Michael L; Tietjen, Gregory T.

Am J Transplant; 21(1): 161-173, 2021 01.

Artigo Inglês | MEDLINE | ID: mdl-32627324

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