Pesquisa | Secretaria de Estado da Saúde

1.

Distinct Cellular Tropism and Immune Responses to Alphavirus Infection.

Kafai, Natasha M; Diamond, Michael S; Fox, Julie M.

Annu Rev Immunol; 40: 615-649, 2022 04 26.

Artigo Inglês | MEDLINE | ID: mdl-35134315

2.

Human Antibodies Protect against Aerosolized Eastern Equine Encephalitis Virus Infection.

Williamson, Lauren E; Gilliland, Theron; Yadav, Pramod K; Binshtein, Elad; Bombardi, Robin; Kose, Nurgun; Nargi, Rachel S; Sutton, Rachel E; Durie, Clarissa L; Armstrong, Erica; Carnahan, Robert H; Walker, Lauren M; Kim, Arthur S; Fox, Julie M; Diamond, Michael S; Ohi, Melanie D; Klimstra, William B; Crowe, James E.

Cell; 183(7): 1884-1900.e23, 2020 12 23.

Artigo Inglês | MEDLINE | ID: mdl-33301709

3.

A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies.

Hassan, Ahmed O; Case, James Brett; Winkler, Emma S; Thackray, Larissa B; Kafai, Natasha M; Bailey, Adam L; McCune, Broc T; Fox, Julie M; Chen, Rita E; Alsoussi, Wafaa B; Turner, Jackson S; Schmitz, Aaron J; Lei, Tingting; Shrihari, Swathi; Keeler, Shamus P; Fremont, Daved H; Greco, Suellen; McCray, Paul B; Perlman, Stanley; Holtzman, Michael J; Ellebedy, Ali H; Diamond, Michael S.

Cell; 182(3): 744-753.e4, 2020 08 06.

Artigo Inglês | MEDLINE | ID: mdl-32553273

4.

A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2.

Hassan, Ahmed O; Kafai, Natasha M; Dmitriev, Igor P; Fox, Julie M; Smith, Brittany K; Harvey, Ian B; Chen, Rita E; Winkler, Emma S; Wessel, Alex W; Case, James Brett; Kashentseva, Elena; McCune, Broc T; Bailey, Adam L; Zhao, Haiyan; VanBlargan, Laura A; Dai, Ya-Nan; Ma, Meisheng; Adams, Lucas J; Shrihari, Swathi; Danis, Jonathan E; Gralinski, Lisa E; Hou, Yixuan J; Schäfer, Alexandra; Kim, Arthur S; Keeler, Shamus P; Weiskopf, Daniela; Baric, Ralph S; Holtzman, Michael J; Fremont, Daved H; Curiel, David T; Diamond, Michael S.

Cell; 183(1): 169-184.e13, 2020 10 01.

Artigo Inglês | MEDLINE | ID: mdl-32931734

5.

SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function.

Winkler, Emma S; Bailey, Adam L; Kafai, Natasha M; Nair, Sharmila; McCune, Broc T; Yu, Jinsheng; Fox, Julie M; Chen, Rita E; Earnest, James T; Keeler, Shamus P; Ritter, Jon H; Kang, Liang-I; Dort, Sarah; Robichaud, Annette; Head, Richard; Holtzman, Michael J; Diamond, Michael S.

Nat Immunol; 21(11): 1327-1335, 2020 11.

Artigo Inglês | MEDLINE | ID: mdl-32839612

6.

Publisher Correction: SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function.

Winkler, Emma S; Bailey, Adam L; Kafai, Natasha M; Nair, Sharmila; McCune, Broc T; Yu, Jinsheng; Fox, Julie M; Chen, Rita E; Earnest, James T; Keeler, Shamus P; Ritter, Jon H; Kang, Liang-I; Dort, Sarah; Robichaud, Annette; Head, Richard; Holtzman, Michael J; Diamond, Michael S.

Nat Immunol; 21(11): 1470, 2020 Nov.

Artigo Inglês | MEDLINE | ID: mdl-32879513

7.

Potently neutralizing and protective human antibodies against SARS-CoV-2.

Zost, Seth J; Gilchuk, Pavlo; Case, James Brett; Binshtein, Elad; Chen, Rita E; Nkolola, Joseph P; Schäfer, Alexandra; Reidy, Joseph X; Trivette, Andrew; Nargi, Rachel S; Sutton, Rachel E; Suryadevara, Naveenchandra; Martinez, David R; Williamson, Lauren E; Chen, Elaine C; Jones, Taylor; Day, Samuel; Myers, Luke; Hassan, Ahmed O; Kafai, Natasha M; Winkler, Emma S; Fox, Julie M; Shrihari, Swathi; Mueller, Benjamin K; Meiler, Jens; Chandrashekar, Abishek; Mercado, Noe B; Steinhardt, James J; Ren, Kuishu; Loo, Yueh-Ming; Kallewaard, Nicole L; McCune, Broc T; Keeler, Shamus P; Holtzman, Michael J; Barouch, Dan H; Gralinski, Lisa E; Baric, Ralph S; Thackray, Larissa B; Diamond, Michael S; Carnahan, Robert H; Crowe, James E.

Nature; 584(7821): 443-449, 2020 08.

Artigo Inglês | MEDLINE | ID: mdl-32668443

8.

Structural basis of Chikungunya virus inhibition by monoclonal antibodies.

Zhou, Qun Fei; Fox, Julie M; Earnest, James T; Ng, Thiam-Seng; Kim, Arthur S; Fibriansah, Guntur; Kostyuchenko, Victor A; Shi, Jian; Shu, Bo; Diamond, Michael S; Lok, Shee-Mei.

Proc Natl Acad Sci U S A; 117(44): 27637-27645, 2020 11 03.

Artigo Inglês | MEDLINE | ID: mdl-33087569

9.

A cross-reactive antibody protects against Ross River virus musculoskeletal disease despite rapid neutralization escape in mice.

Fox, Julie M; Huang, Ling; Tahan, Stephen; Powell, Laura A; Crowe, James E; Wang, David; Diamond, Michael S.

PLoS Pathog; 16(8): e1008743, 2020 08.

Artigo Inglês | MEDLINE | ID: mdl-32760128

10.

Human monoclonal antibodies against Ross River virus target epitopes within the E2 protein and protect against disease.

Powell, Laura A; Fox, Julie M; Kose, Nurgun; Kim, Arthur S; Majedi, Mahsa; Bombardi, Robin; Carnahan, Robert H; Slaughter, James C; Morrison, Thomas E; Diamond, Michael S; Crowe, James E.

PLoS Pathog; 16(5): e1008517, 2020 05.

Artigo Inglês | MEDLINE | ID: mdl-32365139

11.

A Potently Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection.

Alsoussi, Wafaa B; Turner, Jackson S; Case, James B; Zhao, Haiyan; Schmitz, Aaron J; Zhou, Julian Q; Chen, Rita E; Lei, Tingting; Rizk, Amena A; McIntire, Katherine M; Winkler, Emma S; Fox, Julie M; Kafai, Natasha M; Thackray, Larissa B; Hassan, Ahmed O; Amanat, Fatima; Krammer, Florian; Watson, Corey T; Kleinstein, Steven H; Fremont, Daved H; Diamond, Michael S; Ellebedy, Ali H.

J Immunol; 205(4): 915-922, 2020 08 15.

Artigo Inglês | MEDLINE | ID: mdl-32591393

12.

Modified mRNA Vaccines Protect against Zika Virus Infection.

Richner, Justin M; Himansu, Sunny; Dowd, Kimberly A; Butler, Scott L; Salazar, Vanessa; Fox, Julie M; Julander, Justin G; Tang, William W; Shresta, Sujan; Pierson, Theodore C; Ciaramella, Giuseppe; Diamond, Michael S.

Cell; 168(6): 1114-1125.e10, 2017 03 09.

Artigo Inglês | MEDLINE | ID: mdl-28222903

13.

Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.

Fox, Julie M; Long, Feng; Edeling, Melissa A; Lin, Hueylie; van Duijl-Richter, Mareike K S; Fong, Rachel H; Kahle, Kristen M; Smit, Jolanda M; Jin, Jing; Simmons, Graham; Doranz, Benjamin J; Crowe, James E; Fremont, Daved H; Rossmann, Michael G; Diamond, Michael S.

Cell; 163(5): 1095-1107, 2015 Nov 19.

Artigo Inglês | MEDLINE | ID: mdl-26553503

14.

Modified mRNA Vaccines Protect against Zika Virus Infection.

Richner, Justin M; Himansu, Sunny; Dowd, Kimberly A; Butler, Scott L; Salazar, Vanessa; Fox, Julie M; Julander, Justin G; Tang, William W; Shresta, Sujan; Pierson, Theodore C; Ciaramella, Giuseppe; Diamond, Michael S.

Cell; 169(1): 176, 2017 03 23.

Artigo Inglês | MEDLINE | ID: mdl-28340344

15.

Mxra8 is a receptor for multiple arthritogenic alphaviruses.

Zhang, Rong; Kim, Arthur S; Fox, Julie M; Nair, Sharmila; Basore, Katherine; Klimstra, William B; Rimkunas, Rebecca; Fong, Rachel H; Lin, Hueylie; Poddar, Subhajit; Crowe, James E; Doranz, Benjamin J; Fremont, Daved H; Diamond, Michael S.

Nature; 557(7706): 570-574, 2018 05.

Artigo Inglês | MEDLINE | ID: mdl-29769725

16.

Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice.

Sapparapu, Gopal; Fernandez, Estefania; Kose, Nurgun; Fox, Julie M; Bombardi, Robin G; Zhao, Haiyan; Nelson, Christopher A; Bryan, Aubrey L; Barnes, Trevor; Davidson, Edgar; Mysorekar, Indira U; Fremont, Daved H; Doranz, Benjamin J; Diamond, Michael S; Crowe, James E.

Nature; 540(7633): 443-447, 2016 12 15.

Artigo Inglês | MEDLINE | ID: mdl-27819683

17.

Requirement of Fc-Fc Gamma Receptor Interaction for Antibody-Based Protection against Emerging Virus Infections.

Keeler, Shamus P; Fox, Julie M.

Viruses; 13(6)2021 05 31.

Artigo Inglês | MEDLINE | ID: mdl-34072720

18.

A Simplified Quantitative Real-Time PCR Assay for Monitoring SARS-CoV-2 Growth in Cell Culture.

Shema Mugisha, Christian; Vuong, Hung R; Puray-Chavez, Maritza; Bailey, Adam L; Fox, Julie M; Chen, Rita E; Wessel, Alex W; Scott, Jason M; Harastani, Houda H; Boon, Adrianus C M; Shin, Haina; Kutluay, Sebla B.

mSphere; 5(5)2020 09 02.

Artigo Inglês | MEDLINE | ID: mdl-32878932

19.

An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis.

Kim, Arthur S; Zimmerman, Ofer; Fox, Julie M; Nelson, Christopher A; Basore, Katherine; Zhang, Rong; Durnell, Lorellin; Desai, Chandni; Bullock, Christopher; Deem, Sharon L; Oppenheimer, Jonas; Shapiro, Beth; Wang, Ting; Cherry, Sara; Coyne, Carolyn B; Handley, Scott A; Landis, Michael J; Fremont, Daved H; Diamond, Michael S.

Cell Host Microbe; 27(3): 428-440.e9, 2020 03 11.

Artigo Inglês | MEDLINE | ID: mdl-32075743

20.

Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.

Powell, Laura A; Miller, Andrew; Fox, Julie M; Kose, Nurgun; Klose, Thomas; Kim, Arthur S; Bombardi, Robin; Tennekoon, Rashika N; Dharshan de Silva, A; Carnahan, Robert H; Diamond, Michael S; Rossmann, Michael G; Kuhn, Richard J; Crowe, James E.

Cell Host Microbe; 28(5): 699-711.e7, 2020 11 11.

Artigo Inglês | MEDLINE | ID: mdl-32783883

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Distinct Cellular Tropism and Immune Responses to Alphavirus Infection.

Human Antibodies Protect against Aerosolized Eastern Equine Encephalitis Virus Infection.

A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies.

A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2.

SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function.

Publisher Correction: SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function.

Potently neutralizing and protective human antibodies against SARS-CoV-2.

Structural basis of Chikungunya virus inhibition by monoclonal antibodies.

A cross-reactive antibody protects against Ross River virus musculoskeletal disease despite rapid neutralization escape in mice.

Human monoclonal antibodies against Ross River virus target epitopes within the E2 protein and protect against disease.

A Potently Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection.

Modified mRNA Vaccines Protect against Zika Virus Infection.

Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.

Modified mRNA Vaccines Protect against Zika Virus Infection.

Mxra8 is a receptor for multiple arthritogenic alphaviruses.

Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice.

Requirement of Fc-Fc Gamma Receptor Interaction for Antibody-Based Protection against Emerging Virus Infections.

A Simplified Quantitative Real-Time PCR Assay for Monitoring SARS-CoV-2 Growth in Cell Culture.

An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis.

Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.