Pesquisa | Secretaria de Estado da Saúde

1.

Spatiotemporal Adaptations of Macrophage and Dendritic Cell Development and Function.

Roquilly, Antoine; Mintern, Justine D; Villadangos, Jose A.

Annu Rev Immunol; 40: 525-557, 2022 04 26.

Artigo Inglês | MEDLINE | ID: mdl-35130030

2.

MHC Class II Ubiquitination Regulates Dendritic Cell Function and Immunity.

Wilson, Kayla R; Jenika, Devi; Blum, Annabelle B; Macri, Christophe; Xu, Bangyan; Liu, Haiyin; Schriek, Patrick; Schienstock, Dominik; Francis, Lauren; Makota, F Victor; Ishido, Satoshi; Mueller, Scott N; Lahoud, Mireille H; Caminschi, Irina; Edgington-Mitchell, Laura E; Villadangos, Jose A; Mintern, Justine D.

J Immunol; 207(9): 2255-2264, 2021 11 01.

Artigo Inglês | MEDLINE | ID: mdl-34599081

3.

Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens.

McWilliam, Hamish E G; Mak, Jeffrey Y W; Awad, Wael; Zorkau, Matthew; Cruz-Gomez, Sebastian; Lim, Hui Jing; Yan, Yuting; Wormald, Sam; Dagley, Laura F; Eckle, Sidonia B G; Corbett, Alexandra J; Liu, Haiyin; Li, Shihan; Reddiex, Scott J J; Mintern, Justine D; Liu, Ligong; McCluskey, James; Rossjohn, Jamie; Fairlie, David P; Villadangos, Jose A.

Proc Natl Acad Sci U S A; 117(40): 24974-24985, 2020 10 06.

Artigo Inglês | MEDLINE | ID: mdl-32958637

4.

Mpeg1 is not essential for antibacterial or antiviral immunity, but is implicated in antigen presentation.

Ebrahimnezhaddarzi, Salimeh; Bird, Catherina H; Allison, Cody C; Tuipulotu, Daniel E; Kostoulias, Xenia; Macri, Christophe; Stutz, Michael D; Abraham, Gilu; Kaiserman, Dion; Pang, Siew Siew; Man, Si Ming; Mintern, Justine D; Naderer, Thomas; Peleg, Anton Y; Pellegrini, Marc; Whisstock, James C; Bird, Phillip I.

Immunol Cell Biol; 100(7): 529-546, 2022 Aug.

Artigo Inglês | MEDLINE | ID: mdl-35471730

5.

Ubiquitination of MHC Class II Is Required for Development of Regulatory but Not Conventional CD4⁺ T Cells.

Liu, Haiyin; Wilson, Kayla R; Schriek, Patrick; Macri, Christophe; Blum, Annabelle B; Francis, Lauren; Heinlein, Melanie; Nataraja, Champa; Harris, James; Jones, Sarah A; Gray, Daniel H D; Villadangos, Jose A; Mintern, Justine D.

J Immunol; 205(5): 1207-1216, 2020 09 01.

Artigo Inglês | MEDLINE | ID: mdl-32747505

6.

Dendritic cell Flt3 - regulation, roles and repercussions for immunotherapy.

Wilson, Kayla R; Villadangos, Jose A; Mintern, Justine D.

Immunol Cell Biol; 99(9): 962-971, 2021 10.

Artigo Inglês | MEDLINE | ID: mdl-34097779

7.

Opportunities for innovation: Building on the success of lipid nanoparticle vaccines.

Huang, Jessica; Yuen, Daniel; Mintern, Justine D; Johnston, Angus P R.

Curr Opin Colloid Interface Sci; 55: 101468, 2021 Oct.

Artigo Inglês | MEDLINE | ID: mdl-34093062

8.

The intracellular pathway for the presentation of vitamin B-related antigens by the antigen-presenting molecule MR1.

McWilliam, Hamish E G; Eckle, Sidonia B G; Theodossis, Alex; Liu, Ligong; Chen, Zhenjun; Wubben, Jacinta M; Fairlie, David P; Strugnell, Richard A; Mintern, Justine D; McCluskey, James; Rossjohn, Jamie; Villadangos, Jose A.

Nat Immunol; 17(5): 531-7, 2016 May.

Artigo Inglês | MEDLINE | ID: mdl-27043408

9.

Local Modulation of Antigen-Presenting Cell Development after Resolution of Pneumonia Induces Long-Term Susceptibility to Secondary Infections.

Roquilly, Antoine; McWilliam, Hamish E G; Jacqueline, Cedric; Tian, Zehua; Cinotti, Raphael; Rimbert, Marie; Wakim, Linda; Caminschi, Irina; Lahoud, Mireille H; Belz, Gabrielle T; Kallies, Axel; Mintern, Justine D; Asehnoune, Karim; Villadangos, Jose A.

Immunity; 47(1): 135-147.e5, 2017 07 18.

Artigo Inglês | MEDLINE | ID: mdl-28723546

10.

Enhanced survival of lung tissue-resident memory CD8âº T cells during infection with influenza virus due to selective expression of IFITM3.

Wakim, Linda M; Gupta, Nishma; Mintern, Justine D; Villadangos, Jose A.

Nat Immunol; 14(3): 238-45, 2013 Mar.

Artigo Inglês | MEDLINE | ID: mdl-23354485

11.

Transience of MHC Class I-restricted antigen presentation after influenza A virus infection.

Mintern, Justine D; Bedoui, Sammy; Davey, Gayle M; Moffat, Jessica M; Doherty, Peter C; Turner, Stephen J.

Proc Natl Acad Sci U S A; 106(16): 6724-9, 2009 Apr 21.

Artigo Inglês | MEDLINE | ID: mdl-19346476

12.

Tissue destruction caused by cytotoxic T lymphocytes induces deletional tolerance.

Parish, Ian A; Waithman, Jason; Davey, Gayle M; Belz, Gabrielle T; Mintern, Justine D; Kurts, Christian; Sutherland, Robyn M; Carbone, Francis R; Heath, William R.

Proc Natl Acad Sci U S A; 106(10): 3901-6, 2009 Mar 10.

Artigo Inglês | MEDLINE | ID: mdl-19234128

13.

Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity.

Guillonneau, Carole; Mintern, Justine D; Hubert, François-Xavier; Hurt, Aeron C; Besra, Gurdyal S; Porcelli, Steven; Barr, Ian G; Doherty, Peter C; Godfrey, Dale I; Turner, Stephen J.

Proc Natl Acad Sci U S A; 106(9): 3330-5, 2009 Mar 03.

Artigo Inglês | MEDLINE | ID: mdl-19211791

14.

Marginal zone B cells acquire dendritic cell functions by trogocytosis.

Schriek, Patrick; Ching, Alan C; Moily, Nagaraj S; Moffat, Jessica; Beattie, Lynette; Steiner, Thiago M; Hosking, Laine M; Thurman, Joshua M; Holers, V Michael; Ishido, Satoshi; Lahoud, Mireille H; Caminschi, Irina; Heath, William R; Mintern, Justine D; Villadangos, Jose A.

Science; 375(6581): eabf7470, 2022 02 11.

Artigo Inglês | MEDLINE | ID: mdl-35143312

15.

Ubiquitin-like protein 3 (UBL3) is required for MARCH ubiquitination of major histocompatibility complex class II and CD86.

Liu, Haiyin; Wilson, Kayla R; Firth, Ashley M; Macri, Christophe; Schriek, Patrick; Blum, Annabelle B; Villar, Javiera; Wormald, Samuel; Shambrook, Mitch; Xu, Bangyan; Lim, Hui Jing; McWilliam, Hamish E G; Hill, Andrew F; Edgington-Mitchell, Laura E; Caminschi, Irina; Lahoud, Mireille H; Segura, Elodie; Herold, Marco J; Villadangos, Jose A; Mintern, Justine D.

Nat Commun; 13(1): 1934, 2022 04 11.

Artigo Inglês | MEDLINE | ID: mdl-35411049

16.

Therapeutic inhibition of the SRC-kinase HCK facilitates T cell tumor infiltration and improves response to immunotherapy.

Poh, Ashleigh R; Love, Christopher G; Chisanga, David; Steer, James H; Baloyan, David; Chopin, Michaël; Nutt, Stephen; Rautela, Jai; Huntington, Nicholas D; Etemadi, Nima; O'Brien, Megan; O'Keefe, Ryan; Ellies, Lesley G; Macri, Christophe; Mintern, Justine D; Whitehead, Lachlan; Gangadhara, Gangadhara; Boon, Louis; Chand, Ashwini L; Lowell, Clifford A; Shi, Wei; Pixley, Fiona J; Ernst, Matthias.

Sci Adv; 8(25): eabl7882, 2022 Jun 24.

Artigo Inglês | MEDLINE | ID: mdl-35731867

17.

The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments.

Zhang, Jian-Guo; Czabotar, Peter E; Policheni, Antonia N; Caminschi, Irina; Wan, Soo San; Kitsoulis, Susie; Tullett, Kirsteen M; Robin, Adeline Y; Brammananth, Rajini; van Delft, Mark F; Lu, Jinhua; O'Reilly, Lorraine A; Josefsson, Emma C; Kile, Benjamin T; Chin, Wei Jin; Mintern, Justine D; Olshina, Maya A; Wong, Wilson; Baum, Jake; Wright, Mark D; Huang, David C S; Mohandas, Narla; Coppel, Ross L; Colman, Peter M; Nicola, Nicos A; Shortman, Ken; Lahoud, Mireille H.

Immunity; 36(4): 646-57, 2012 Apr 20.

Artigo Inglês | MEDLINE | ID: mdl-22483802

18.

Blood-stage Plasmodium infection induces CD8+ T lymphocytes to parasite-expressed antigens, largely regulated by CD8alpha+ dendritic cells.

Lundie, Rachel J; de Koning-Ward, Tania F; Davey, Gayle M; Nie, Catherine Q; Hansen, Diana S; Lau, Lei Shong; Mintern, Justine D; Belz, Gabrielle T; Schofield, Louis; Carbone, Francis R; Villadangos, Jose A; Crabb, Brendan S; Heath, William R.

Proc Natl Acad Sci U S A; 105(38): 14509-14, 2008 Sep 23.

Artigo Inglês | MEDLINE | ID: mdl-18799734

19.

Regulation of dendritic cell function by Fc-Î³-receptors and the neonatal Fc receptor.

Macri, Christophe; Morgan, Huw; Villadangos, Jose A; Mintern, Justine D.

Mol Immunol; 139: 193-201, 2021 11.

Artigo Inglês | MEDLINE | ID: mdl-34560415

20.

Targeted delivery of mycophenolic acid to the mesenteric lymph node using a triglyceride mimetic prodrug approach enhances gut-specific immunomodulation in mice.

Kochappan, Ruby; Cao, Enyuan; Han, Sifei; Hu, Luojuan; Quach, Tim; Senyschyn, Danielle; Ferreira, Vilena Ivanova; Lee, Given; Leong, Nathania; Sharma, Garima; Lim, Shea Fern; Nowell, Cameron J; Chen, Ziqi; von Andrian, Ulrich H; Bonner, Daniel; Mintern, Justine D; Simpson, Jamie S; Trevaskis, Natalie L; Porter, Christopher J H.

J Control Release; 332: 636-651, 2021 04 10.

Artigo Inglês | MEDLINE | ID: mdl-33609620

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