Pesquisa | Secretaria de Estado da Saúde

1.

Inflammatory Caspases: Toward a Unified Model for Caspase Activation by Inflammasomes.

Ross, Connie; Chan, Amy H; von Pein, Jessica B; Maddugoda, Madhavi P; Boucher, Dave; Schroder, Kate.

Annu Rev Immunol; 40: 249-269, 2022 04 26.

Artigo Inglês | MEDLINE | ID: mdl-35080918

2.

An alloy of zinc and innate immunity: Galvanising host defence against infection.

von Pein, Jessica B; Stocks, Claudia J; Schembri, Mark A; Kapetanovic, Ronan; Sweet, Matthew J.

Cell Microbiol; 23(1): e13268, 2021 01.

Artigo Inglês | MEDLINE | ID: mdl-32975847

3.

Modified horseshoe crab peptides target and kill bacteria inside host cells.

Amiss, Anna S; von Pein, Jessica B; Webb, Jessica R; Condon, Nicholas D; Harvey, Peta J; Phan, Minh-Duy; Schembri, Mark A; Currie, Bart J; Sweet, Matthew J; Craik, David J; Kapetanovic, Ronan; Henriques, Sónia Troeira; Lawrence, Nicole.

Cell Mol Life Sci; 79(1): 38, 2021 Dec 31.

Artigo Inglês | MEDLINE | ID: mdl-34971427

4.

Frontline Science: LPS-inducible SLC30A1 drives human macrophage-mediated zinc toxicity against intracellular Escherichia coli.

Stocks, Claudia J; von Pein, Jessica B; Curson, James E B; Rae, James; Phan, Minh-Duy; Foo, Darren; Bokil, Nilesh J; Kambe, Taiho; Peters, Kate M; Parton, Robert G; Schembri, Mark A; Kapetanovic, Ronan; Sweet, Matthew J.

J Leukoc Biol; 109(2): 287-297, 2021 02.

Artigo Inglês | MEDLINE | ID: mdl-32441444

5.

Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1ß Secretion.

Chen, Kaiwen W; Lawlor, Kate E; von Pein, Jessica B; Boucher, Dave; Gerlic, Motti; Croker, Ben A; Bezbradica, Jelena S; Vince, James E; Schroder, Kate.

J Immunol; 200(10): 3341-3346, 2018 05 15.

Artigo Inglês | MEDLINE | ID: mdl-29661823

6.

Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2.

Das Gupta, Kaustav; Shakespear, Melanie R; Curson, James E B; Murthy, Ambika M V; Iyer, Abishek; Hodson, Mark P; Ramnath, Divya; Tillu, Vikas A; von Pein, Jessica B; Reid, Robert C; Tunny, Kathryn; Hohenhaus, Daniel M; Moradi, Shayli Varasteh; Kelly, Gregory M; Kobayashi, Takumi; Gunter, Jennifer H; Stevenson, Alexander J; Xu, Weijun; Luo, Lin; Jones, Alun; Johnston, Wayne A; Blumenthal, Antje; Alexandrov, Kirill; Collins, Brett M; Stow, Jennifer L; Fairlie, David P; Sweet, Matthew J.

Cell Rep; 30(8): 2712-2728.e8, 2020 02 25.

Artigo Inglês | MEDLINE | ID: mdl-32101747

7.

Noncanonical inflammasome signaling elicits gasdermin D-dependent neutrophil extracellular traps.

Chen, Kaiwen W; Monteleone, Mercedes; Boucher, Dave; Sollberger, Gabriel; Ramnath, Divya; Condon, Nicholas D; von Pein, Jessica B; Broz, Petr; Sweet, Matthew J; Schroder, Kate.

Sci Immunol; 3(26)2018 08 24.

Artigo Inglês | MEDLINE | ID: mdl-30143554

8.

Interleukin-1ß Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion.

Monteleone, Mercedes; Stanley, Amanda C; Chen, Kaiwen W; Brown, Darren L; Bezbradica, Jelena S; von Pein, Jessica B; Holley, Caroline L; Boucher, Dave; Shakespear, Melanie R; Kapetanovic, Ronan; Rolfes, Verena; Sweet, Matthew J; Stow, Jennifer L; Schroder, Kate.

Cell Rep; 24(6): 1425-1433, 2018 08 07.

Artigo Inglês | MEDLINE | ID: mdl-30089254

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