α1, 6-fucosyltransferase and tumor: Recent progress / 第二军医大学学报

Core fucose glycosylation catalyzed by α1, 6-fucosetransferase(Fut8) is an important way for protein post-translational modification and functional regulation; it directly influences a series of biological characteristics of cells and is always seen under some pathological conditions. This paper reviews the recent studies on the regulation, biological function of Fut8 and its relationship with different kinds of tumors.