Spontaneous Resolution of Iatrogenic Aortic Dissection After Coronary Arterial Stenting.

Although rare, coronary arterial angiography carries a life-threatening risk of iatrogenic aortic dissection (AD). Given the paucity of data, an optimal treatment option for iatrogenic AD is a conundrum. In this report, we present our experience of spontaneous resolution of AD in a patient with catheter-driven iatrogenic AD during coronary arterial intervention. (Level of Difficulty: Advanced.).

Surgical treatment of acute aortic dissection Stanford type A in the third trimester of pregnancy: A case report.

BACKGROUND: Aortic dissection is rare in pregnancy, but it is often life-threatening. Thus, early diagnosis and optimal treatment are crucial. In addition, regular multidisciplinary care plays an important role in improving the therapeutic outcome. CASE: A 31-year-old pregnant woman (gravida 2, para 1, abortus 0) was transferred to our centre at 34 weeks of gestation with onset of dyspnoea and serious chest pain radiating to her back. Ultrasonography unexpectedly revealed a dilation of the aortic root with a sign of dissection. Computed tomography confirmed a type A aortic dissection based on the Stanford classification. She was successfully treated by caesarean section prior to open repair of acute type A dissection and received multidisciplinary care. The patient was discharged on the 16th postoperative day, and the baby is still alive without adverse events. CONCLUSION: Aortic dissection in pregnancy is relatively rare, but physicians should be on high alert for the condition when a pregnant woman has chest pain. Early diagnosis and adequate treatment in addition to regular multidisciplinary care are crucial to achieve favourable results.

Sole Obstruction of the Inferior Mesenteric Artery With Acute Aortic Dissection Causing Critical Mesenteric Ischemia.

Inferior mesenteric artery obstruction rarely causes critical mesenteric ischemia, because of the good collateral blood supply. We report a rare case of critical mesenteric ischemia due to sole inferior mesenteric artery obstruction accompanied by acute aortic dissection. Early diagnosis and treatment of mesenteric ischemia are important. (Level of Difficulty: Advanced.).

Successful Conservative Treatment of a Type A Aortic Intramural Hematoma.

Type A intramural hematoma (IMH) constitutes a variant of acute aortic syndrome. Western guidelines support an aggressive surgical approach, whereas Asian centers propose initial conservative treatment. Further expanding on this notion, we present a case of conservative subacute type A IMH management, resulting in radical hematoma resorption within 4 weeks. (Level of Difficulty: Beginner.).

Genetic Deletion of Socs3 in Smooth Muscle Cells Ameliorates Aortic Dissection in Mice.

Aortic dissection (AD) is the acute destruction of aortic wall and is reportedly induced by inflammatory response. Here we investigated the role of smooth muscle Socs3 (a negative regulator of Janus kinases/signal transducer and activator of transcription signaling) in AD pathogenesis using a mouse model generated via ß-aminopropionitrile and angiotensin II infusion. Socs3 deletion specifically in smooth muscle cells yielded a chronic inflammatory response of the aortic wall, which was associated with increased fibroblasts, reinforced aortic tensile strength, and less-severe tissue destruction. Although an acute inflammatory response is detrimental in AD, smooth muscle-regulated inflammatory response seemed protective against AD.