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Understanding the global epidemiology of AML is critical for assessing therapeutic demand and informing healthcare resource allocation. This study estimated current and future AML incidence in 27 countries, described AML survival trends in the United States, and calculated average years of life lost (AYLL). Incidence rates were age-standardized using rates from IARC's Cancer Incidence in Five Continents and SEER databases and ranged from 0.70 to 3.23 cases per 100,000 persons. Crude incidence rates were projected from 2024 to 2040; growth varied from +1% to +46%. Median overall survival was derived from SEER databases and increased from 4 to 11 months over the last 40 years. Median AYLL of 18.6 years was estimated for 27 countries. This study projected significant growth in new AML diagnoses over the next two decades. Despite improvements in survival over the last four decades, median survival among AML patients remains poor highlighting the need for novel treatments.
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BACKGROUND: HIV epidemic is mostly targeted adults and has numerous negative health, social, economic, cultural and political consequences. In this study Life Expectancy (LE) and Average Years of Life Lost (AYLL) in HIV/AIDS patients are estimated. MATERIALS AND METHODS: In this descriptive study all the patients at the age of 18 and more under the care of BandarAbbas Behavioral Disorders Counseling Center (BBDCC) during 2005-2015 are included. The town of BandarAbbas is center of Hormozgan Province in southern Iran. LE and AYLL have been estimated based on Life Table. RESULTS: One hundred thirty four of the 426 eligible patients died during the study period. Compared to the general population LE for HIV/AIDS patients at age 20 is 46 years less in comparison with the general population of BandarAbbas. Moreover, a total of 8839 years of life lost during 2005-2015. CONCLUSION: LE in HIV/AIDS patients is less than LE among BandarAbbas general population and AYLL among them is more than general population. Most of the years of life lost are preventable if the health care system seriously will implement programs to control HIV/AIDS.
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Objective] To analyze the death causes of malignant tumors among residents in Ouhai District of Wenzhou City and provide basis for formulating targeted intervention . [ Methods] The causes of death from 2010 to 2012 were classified according to International Classification of Diseases ( ICD-10 ) and statistically analyzed by the death cause statistical software DeathReg 2005, Excel, and SPSS13.0. [ Results] The annual average mortality of malignant tumors among residents in Ouhai District was 150.41/100 000, the standardized mortality rate was 130.02/100 000.The mortality of malignant tumors was 197.48/100 000 in males and 101.93/100 000 in females, and there was significant gender difference .The top five death causes of malignant tumors were lung cancer , hepatic carcinoma , gastric cancer , colon-rectum-anus cancer , and esophagus carcinoma .The malignant tumor death causes in different age groups were different , and the mortality rate rose with the increase of age .The potential years of life lost ( PYLL) of malignant tumor death was 14 634.5 person-years.The average years of life lost ( AYLL) and PYLL rate were 8.01 years/person and 12.05‰, respectively. [Conclusion] The first cause of death among residents is malignant tumor in Ouhai District of Wenzhou City .According to characteristics of different tumors for different population, comprehensive intervention measures should be implemented to reduce the morbidity of malignant tumors .