RESUMO
Automated detection of vision threatening eye disease based on high resolution retinal fundus images requires accurate segmentation of the blood vessels. In this regard, detection and segmentation of finer vessels, which are obscured by a considerable degree of noise and poor illumination, is particularly challenging. These noises include (systematic) additive noise and multiplicative (speckle) noise, which arise due to various practical limitations of the fundus imaging systems. To address this inherent issue, we present an efficient unsupervised vessel segmentation strategy as a step towards accurate classification of eye diseases from the noisy fundus images. To that end, an ensemble block matching 3D (BM3D) speckle filter is proposed for removal of unwanted noise leading to improved detection. The BM3D-speckle filter, despite its ability to recover finer details (i.e., vessels in fundus images), yields a pattern of checkerboard artifacts in the aftermath of multiplicative (speckle) noise removal. These artifacts are generally ignored in the case of satellite images; however, in the case of fundus images, these artifacts have a degenerating effect on the segmentation or detection of fine vessels. To counter that, an ensemble of BM3D-speckle filter is proposed to suppress these artifacts while further sharpening the recovered vessels. This is subsequently used to devise an improved unsupervised segmentation strategy that can detect fine vessels even in the presence of dominant noise and yields an overall much improved accuracy. Testing was carried out on three publicly available databases namely Structured Analysis of the Retina (STARE), Digital Retinal Images for Vessel Extraction (DRIVE) and CHASE_DB1. We have achieved a sensitivity of 82.88, 81.41 and 82.03 on DRIVE, SATARE, and CHASE_DB1, respectively. The accuracy is also boosted to 95.41, 95.70 and 95.61 on DRIVE, SATARE, and CHASE_DB1, respectively. The performance of the proposed methods on images with pathologies was observed to be more convincing than the performance of similar state-of-the-art methods.
RESUMO
BACKGROUND AND OBJECTIVE: The purpose of this paper is to propose a fully automated liver vessel segmentation algorithm including portal vein and hepatic vein on contrast enhanced CTA images. METHODS: First, points of a vessel candidate region are extracted from 3-dimensional (3D) CTA image. To generate accurate points, we reduce 3D segmentation problem to 2D problem by generating multiple maximum intensity (MI) images. After the segmentation of MI images, we back-project pixels to the original 3D domain. We call these voxels as vessel candidates (VCs). A large set of MI images can produce very dense and accurate VCs. Finally, for the accurate segmentation of a vessel region, we propose a newly designed active contour model (ACM) that uses the original image, vessel probability map from dense VCs, and the good prior of an initial contour. RESULTS: We used 55 abdominal CTAs for a parameter study and a quantitative evaluation. We evaluated the performance of the proposed method comparing with other state-of-the-art ACMs for vascular images applied directly to the original data. The result showed that our method successfully segmented vascular structure 25%-122% more accurately than other methods without any extra false positive detection. CONCLUSION: Our model can generate a smooth and accurate boundary of the vessel object and easily extract thin and weak peripheral branch vessels. The proposed approach can automatically segment a liver vessel without any manual interaction. The detailed result can aid further anatomical studies.