The correlation between the cardiovascular instability and the size of the developed ischaemic lesions in patients who underwent carotid stenting.

AIMS: In this study we investigated the relationship between cardiovascular instability and the size of the developed ischaemic lesions during carotid stent implantation by diffusion-weighted (DWI) magnetic resonance (MR) examination. MATERIAL AND METHODS: We retrospectively analyzed anaesthesia reports and follow-up MR examinations after stent implantation of 192 patients in a 3-year period. Nineteen aspects of cardiovascular status were analyzed. We registered the duration of the intervention, low and high blood pressure (BP) values during anaesthesia and heart rates. The fluctuations of BP and heart rate and the time of their compensations after the stent expansion were also recorded. Values were compared with the number and the size of ischaemic lesions on DWI scans. We used Spearman and Kendall rank correlations and Welch's tests for statistical analysis. Values of p ≤ 0.05 were considered as statistically significant. RESULTS: Decreased heart rate significantly correlated with the number (p = 0.0123) and size (p = 0.00323) of ischaemic lesions during stent expansion. Other cardiovascular parameters did not show any significant correlations. CONCLUSIONS: Our results indicate that only heart rate attenuation affects the size of ischaemic lesions; thus the prevention of bradycardia is highly important.

Effect of diltiazem injection on blood pressure control after carotid artery stent implantation / 中国生化药物杂志

Objective To investigate the effect of diltiazem injection on the blood pressure and heart rate of patients with carotid artery stent implantation. Methods 60 patients with carotid artery stent implantation from February 2015 to March 2017 were divided into control group and observation group, with 30 cases in each group. The control group was given conventional medication, the observation group was treated with diltiazem on the basis of routine medication in the control group. The mean arterial pressure (MAP) and heart rate (HR) were measured at 72 hours after operation. The number of patients with low blood pressure was measured. Results The stenosis rate of the two groups was significantly lower than that of the control group, while the observation group was significantly lower than the control group (P<0.05). The blood pressure of the observation group was lower than that of the control group at 72 h after operation, but there was no statistical significance. There was no significant difference between the two groups in the rate of hypotension. Conclusion Application of diltiazem injection can help stabilize the carotid artery stent implantation in patients with blood pressure and heart rate, to avoid the occurrence of accidents.

Effect of diltiazem injection on blood pressure control after carotid artery stent implantation / 中国生化药物杂志

Objective To investigate the effect of diltiazem injection on the blood pressure and heart rate of patients with carotid artery stent implantation. Methods 60 patients with carotid artery stent implantation from February 2015 to March 2017 were divided into control group and observation group, with 30 cases in each group. The control group was given conventional medication, the observation group was treated with diltiazem on the basis of routine medication in the control group. The mean arterial pressure (MAP) and heart rate (HR) were measured at 72 hours after operation. The number of patients with low blood pressure was measured. Results The stenosis rate of the two groups was significantly lower than that of the control group, while the observation group was significantly lower than the control group (P<0.05). The blood pressure of the observation group was lower than that of the control group at 72 h after operation, but there was no statistical significance. There was no significant difference between the two groups in the rate of hypotension. Conclusion Application of diltiazem injection can help stabilize the carotid artery stent implantation in patients with blood pressure and heart rate, to avoid the occurrence of accidents.