Role of hydrogen sulfide in dermatological diseases.

Hydrogen sulfide (H2S), together with carbon monoxide (CO) and nitric oxide (NO), is recognized as a vital gasotransmitter. H2S is biosynthesized by enzymatic pathways in the skin and exerts significant physiological effects on a variety of biological processes, such as apoptosis, modulation of inflammation, cellular proliferation, and regulation of vasodilation. As a major health problem, dermatological diseases affect a large proportion of the population every day. It is urgent to design and develop effective drugs to deal with dermatological diseases. Dermatological diseases can arise from a multitude of etiologies, including neoplastic growth, infectious agents, and inflammatory processes. The abnormal metabolism of H2S is associated with many dermatological diseases, such as melanoma, fibrotic diseases, and psoriasis, suggesting its therapeutic potential in the treatment of these diseases. In addition, therapies based on H2S donors are being developed to treat some of these conditions. In the review, we discuss recent advances in the function of H2S in normal skin, the role of altering H2S metabolism in dermatological diseases, and the therapeutic potential of diverse H2S donors for the treatment of dermatological diseases.

Study on clinic efficacy of Qiwei Liaoshang Powder on empyrosis / 国际中医中药杂志

Objective To investigate the clinic efficacy of Qiwei Liaoshang Powder on empyrosis. Methods 176inpatients suffering empyrosis were included in our study. A prospective randomized study was adopted to evaluate the efficacy of Qiwei Liaoshang Powder, while exposure therapy of San Huang Cream was taken as control. Bacteria culture,healing time, and pain of wounds were compared. Results Qiwei Liaoshang Powder had less healing time, pain and infection rate than San Huang Cream. Conclusion Qiwei Liaoshang Powder is effective to treat empyrosis.