Contamination, spatial distribution, and source contribution of persistent organic pollutants in the soil of Guiyang city, China: a case study.

The contamination of persistent organic pollutants (POPs), including dichlorodiphenyltrichloroethane (DDT), hexachlorocyclohexane (HCH), and polycyclic aromatic hydrocarbon (PAH), is the most studied environmental issue. In 2020, a total of sixty soil samples collected from ten locations in Guiyang were analyzed to assess the presence of four DDTs and HCHs and sixteen PAHs. The concentrations of total DDTs, total HCHs and Σ16PAHs in the soil were between 0.26 and 12.76, 0.23 and 51.80 µg/kg, and 10.02 and 1708.86 µg/kg, respectively. The mean and median concentrations of total DDTs, total HCHs and Σ16PAHs in the soil were 1.04 and 0.26 µg/kg, 4.32 and 0.23 µg/kg, 139.14 and 98.98 µg/kg, respectively. p,p'-DDT, p,p'-DDD and γ-HCH the dominant organochloride pollutants in the soil, while 4-ring PAHs were the dominant PAHs, occupying 41.1-53.6% of the total PAHs in the soil. The highest levels of PAHs in the soil were observed in areas of Guiyang with relatively larger population densities and more developed heave industries. Various diagnostic tools were used to identify the potential sources of the POPs in the soil. The data indicated that DDTs and HCHs were from past and recent common inputs and that mixtures of several combustion activities (biomass, coal and petroleum combustion, diesel, gasoline, and vehicular emissions) were the major sources of PAHs in the Guiyang soil. The results provide information for the assessment of the extent of POP pollution in the Guiyang soil and can help authorities establish environmental protection regulations and soil remediation techniques.

An incentive-based source separation model for sustainable municipal solid waste management in China.

Municipal solid waste (MSW) management (MSWM) is most important and challenging in large urban communities. Sound community-based waste management systems normally include waste reduction and material recycling elements, often entailing the separation of recyclable materials by the residents. To increase the efficiency of source separation and recycling, an incentive-based source separation model was designed and this model was tested in 76 households in Guiyang, a city of almost three million people in southwest China. This model embraced the concepts of rewarding households for sorting organic waste, government funds for waste reduction, and introducing small recycling enterprises for promoting source separation. Results show that after one year of operation, the waste reduction rate was 87.3%, and the comprehensive net benefit under the incentive-based source separation model increased by 18.3 CNY tonne(-1) (2.4 Euros tonne(-1)), compared to that under the normal model. The stakeholder analysis (SA) shows that the centralized MSW disposal enterprises had minimum interest and may oppose the start-up of a new recycling system, while small recycling enterprises had a primary interest in promoting the incentive-based source separation model, but they had the least ability to make any change to the current recycling system. The strategies for promoting this incentive-based source separation model are also discussed in this study.

Growth history of hepatitis C virus among HIV/HCV co-infected patients in Guizhou Province.

Background: The evolutionary and epidemiological history and the regional differences of various hepatitis C virus (HCV) genotypes are complex. Our aim was to better understand the molecular epidemiology and evolutionary dynamics of HCV among HIV/HCV co-infected individuals in Guizhou Province. This information could contribute to improve HCV prevention and control strategies in Guizhou and surrounding provinces. Methods: The HCV RNA was extracted from the serum of HIV/HCV co-infected patients, and reverse transcription/nested PCR was performed to amplify nucleotide sequences of the C-E1 region. Then, the successfully amplified sequences were selected for phylogenetic analysis. The available C-E1 region reference sequences from the surrounding provinces of Guizhou (Guangxi, Yunnan, Hunan, and Sichuan) were retrieved in GenBank, and the evolutionary analysis by Bayesian Markov chain Monte Carlo (MCMC) algorithm was performed using BEAST software to reconstruct a phylogeographic tree in order to explore their migration patterns. Finally, the epidemiological history of HCV in the Guizhou region was retraced by reconstructing Bayesian skyline plots (BSPs) after excluding sequences from surrounding provinces. Results: Among 186 HIV/HCV co-infected patients, the C-E1 region sequence was successfully amplified in 177 cases. Phylogenetic analysis classified these sequences into six subtypes: 1a, 1b, 3a, 3b, 6a, and 6n. Among them, subtype 6a was the most dominant strain (n = 70), followed by 3b (n = 55), 1b (n = 31), 3a (n = 11), 1a (n = 8), and 6n (n = 2). By reconstructing the phylogeographic tree, we estimated that the 6a strain in Guizhou mainly originated from Yunnan and Guangxi, while the 3b strain emerged due to transmission from the IDU network in Yunnan. Subtypes 1b, 3a, 3b, and 6a, as the major subtypes of HCV in HIV/HCV co-infected individuals in Guizhou, emerged and later grew more rapidly than the national average. Notably, BSPs of the currently prevalent HCV predominant strain subtype 6a in Guizhou have shown a rapid population growth since 2004. Although the growth rate slowed down around 2010, this growth has continued to date. Conclusion: Overall, despite the improvement and implementation of a series of HCV prevention and control policies and measures, a delayed growth pattern may indicate a unique history of the spread of 6a in Guizhou. Its trend as the dominant strain in Guizhou in recent years may continue to increase slowly over subsequent years.

Analysis of spatial pattern and influencing factors of private clinics in the main urban area of Guiyang in China from 2021 to 2022 based on multi-source data.

BACKGROUND: Private clinics are important places for residents to obtain daily medical care. However, previous researches mainly focused on public medical institutions but ignored the issue of systematic allocation of social medical resources such as clinics. It is critical to understand the private clinics distribution to analyze the rational allocation of medical resources and the spatial difference. METHODS: Based on the field survey, land census, population density, and economic data from Guiyang, this study analyzes the spatial pattern of private clinics in the main urban area of Guiyang and the influencing factors by using spatial analysis methods such as kernel density, standard deviation ellipses, and geo-detector. RESULTS: The private clinics in the main urban area of Guiyang are characterized by "inner dense, outer sparse dense," showing an overall spatial clustering feature of "four cores and two belts with many points" and "dense inside and sparse outside." Different types of private clinics have distinct spatial distribution characteristics and agglomeration forms. The growth of private clinics is closely linked to the population growth of mountainous cities. The most important factors influencing the spatial pattern of private clinics are residential land factors, followed by traffic factors and population density. The impact of economic, natural, and spatial factors is minimal. When using a geo-detector, the results of multi-factor interaction differ from those of single factors, and factor interactions have greater explanatory power than single factors in clinic distribution. CONCLUSION: This study investigates the geographic distribution and influencing variables of private clinics in typical mountain cities and identifies the causes of the current disparity in the distribution of healthcare resources. It is necessary to gradually develop the primary healthcare system in mountainous cities with legislation, counterpart support, and social resources. While ensuring equal access to health care for low-income people and mobile populations, various medical needs of community members should be fully considered and implemented as soon as possible.

Implementing Climate Change Adaptation in Territory Spatial Planning Systems: Challenges and Approaches Based on Practices in Guiyang.

Integrating climate change adaptation into spatial planning has become a global goal in the field of spatial planning. Despite the various relevant policies proposed by governments, there is still a lack of common practice in the field of climate change research and territory spatial planning preparation and research in China. In this study, climate change adaptation planning in the territory spatial planning system (TSPS), based upon risk assessment, is explored using downscaled climate change prediction data (derived from CMIP5) and prefectural master territory spatial planning (MTSP) data from Guiyang. The study found that such practices, despite their feasibility, still face systemic challenges given the current planning system in China, e.g., the deficiency of climate change impact data and analyses, the absence of essential planning tools, and the unsuitability of the current planning system for the integration of adaptation actions. We propose corresponding approaches based on our empirical planning experience and discuss prospects for relevant research and planning.

The Epidemiological Characteristics of Noncommunicable Diseases and Malignant Tumors in Guiyang, China: Cross-sectional Study.

BACKGROUND: Studies that address the changing characteristics of diseases are of great importance for preventing and controlling the occurrence and development of diseases and for improving health. However, studies of the epidemiological characteristics of noncommunicable diseases (NCDs) and malignant tumors (MTs) of the residents in Guiyang, China, are lacking. OBJECTIVE: The aim of this study was to evaluate the prevalences of NCDs and MTs in residents of Guiyang, Guizhou Province, China, and analyze differences among ages, genders, and regions. METHODS: A multistage stratified cluster sampling method was used. Based on the inclusion and exclusion criteria, 81,517 individuals were selected for the study. Of these, 77,381 (94.9%) participants completed the study. Structured questionnaires were used to collect information on demographic characteristics, NCDs, and MTs. The chi-square test (with 95% confidence intervals) was used to analyze differences in disease prevalence among genders, ages, and geographical regions. RESULTS: The major chronic NCDs of Guiyang residents are obesity, hypertension, and diabetes. MTs in women are mostly breast cancer, cervical cancer, and endometrial cancer, whereas in men, MTs are mainly lung cancer, rectal cancer, and gastric cancer. The prevalences of hypertension and diabetes in women are higher than in men, but the prevalences of lung cancer and gastric cancer in men are higher than in women. The epidemiological characteristics of individuals in different life stages are dissimilar. In terms of regional distribution, the prevalences of the above diseases in the Baiyun and Yunyan districts of Guiyang are relatively high. CONCLUSIONS: Several NCDs (obesity, hypertension, and diabetes) and MTs (women: breast cancer, cervical cancer, and endometrial cancer; men: lung cancer, rectal cancer, and gastric cancer) should be the focus for the prevention and control of chronic diseases in the future. In particular, the Baiyun and Yunyan districts of Guiyang are the important regions to emphasize.

Correlation between Spatio-Temporal Evolution of Habitat Quality and Human Activity Intensity in Typical Mountain Cities: A Case Study of Guiyang City, China.

The acceleration of the urbanization process brings about the expansion of urban land use, while changes in land-use transformation affect the urban habitat quality, and land-use change brings a threat to regional sustainable development. Against such a backdrop, the assessment of land use on the habitat quality and the relationship between the intensity of human activities is becoming a hot spot in terms of the current land use coordinated with habitat quality. Based on the land-use data of Guiyang in 2000, 2005, 2010, 2015 and 2020, the spatial-temporal evolution characteristics of habitat quality in the study area, combined with the spatial correlation between human activity intensity and habitat quality, were hereby analyzed using the InVEST model. The impact of human activity intensity on habitat quality was correspondingly analyzed. The results show that: (1) From 2000 to 2020, the habitat quality level in Guiyang remained stable without drastic changes, but the changes showed hierarchical distribution and were scattered, mainly reflected in the urban expansion areas of the urban-rural fringe and the key areas of industrial development, and the ecological environment quality fluctuated in a small range. (2) From 2000 to 2020, the intensity of human activities in Guiyang was mainly affected by the relatively concentrated distribution, featuring obvious and significant changes. From 2010 to 2015, the high-impact area surrounded the Guanshan Lake New Area, and the regional habitat quality presented a downward trend. In 2020, the high-impact area of the main urban area and the key industrial development zone was expected to be formed, while the low-impact area was still distributed in forest areas with complex natural conditions. (3) From 2000 to 2020, there was a significant positive correlation between human activity intensity and habitat quality in Guiyang, and such a spatial correlation was weak from 2000 to 2005. The period from 2015 to 2020 witnessed the rapid development of urban construction in Guiyang, human construction activities continue to affect the urban habitat quality. The results show that the intensity of human activities on the promoting function of land use, and the dependencies between them should be considered at the same time, and that explorations on the influence of human activities on land-use intensity and habitat quality of space link are crucial to improving the efficiency of urban land use and ecological environment protection, as well as the coordination between land use and the sustainability of urban development.

Assessing ecological literacy and its application based on linguistic ecology: a case study of Guiyang City, China.

To address the frequent emergence of ecological problems, ecology has intersected with various disciplines. From the perspective of linguistic ecology, ecological literacy is an important concept that combines the subjects of ecology and linguistics. It not only discusses ecological issues, but also establishes a linguistic framework. Here, we constructed a quantitative method of assessing ecological literacy from the perspective of linguistic ecology. Ecological literacy was divided into five parts: ecological knowledge literacy, ecological awareness literacy, ecological ethics literacy, ecological emotional literacy, and ecological behavioral literacy. Each of these was set with four quantitative indicators that were evaluated through eight questions. A case study was conducted to investigate the ecological literacy of the inhabitants of Guiyang City, one of China's top ten ecologically advanced cities. The results showed that the proposed assessment method was an effective way to evaluate the level of ecological literacy comprehensively. In the case analysis, the overall ecological literacy level of Guiyang inhabitants was relatively good, and the levels of the five specific dimensions of them in descending order were as follows: ecological ethics literacy, ecological emotional literacy, ecological awareness literacy, ecological knowledge literacy, and ecological behavioral literacy. The results of this study are conducive to the production of targeted ways to improve the level of ecological literacy for sustainable development.

[Enterobius vermicularis infection in Guiyang City, Guizhou Province: a case report].

The report presents a case with Enterobius vermicularis infections in Guiyang City, Guizhou Province, aiming to strengthen the attention to parasitic infections.

Assessment on water resources carrying capacity in karst areas by using an innovative DPESBRM concept model and cloud model.

The shortage of water resources in karst areas is mainly caused by the development of karst landforms, poor availability of water resources and the difficulty of utilization. To reasonably evaluate water resources carrying capacity (WRCC) of karst areas, based on characteristics of urban water resources utilization in karst areas, this study put forward DPESBRM (Driver-Pressure-Engineering water shortage-State-Ecological basis-Response-Management) concept model the first time to build an urban evaluation index system of WRCC in karst areas. Based on this index system and in allusion to uncertainties that exist during the evaluation process, a cloud model is used to represent index weights and perform comprehensive evaluation calculations, which fully considers the randomness and ambiguity of evaluation objects. WRCC from 2009 to 2018 were evaluated and were classified as five grades (Serious overload - Overload - Critical - Weak carrying capacity - Strong carrying capacity). Results proved that WRCC had improved year after year, gradually changing from a serious overload state in 2009 to a strong carrying capacity state in 2018. 2009 and 2016 were classified as I grade (serious overload). 2010 and 2011 were classified as II grade (overload). 2012, 2013 and 2015 were classified as IV grade (weak bearing capacity). 2014, 2017 and 2018 were classified as V grade (strong bearing capacity). Cloud model assessment results are compared with that of TOPSIS method, and assessment results are basically unanimous. It shows that the established WRCC evaluation method based on cloud model in this study is reasonable and feasible. Population density, urbanization rate and per capital water consumption are important driving factors affecting WRCC. Hence, strengthening the construction of water conservancy facilities, optimizing the water consumption structure, improving the efficiency of industrial water use, reducing per capital water consumption, and narrowing urban water supply and demand gap are important measures to ensure WRCC.

Evaluating urban resource and environment carrying capacity by using an innovative indicator system based on eco-civilization-a case study of Guiyang.

A city's sustainable development should occur via harmonious development of urban resource and environment carrying capacity (URECC) and economic growth. By following laws of harmonious development of man, nature, and society, ecological civilization refers to the sum total of material, spiritual, and institutional achievements made by mankind in promoting social, economic, and cultural development. It is an important way of realizing sustained development in China, which has been taken as an important way and method for solving the conflict between environmental problems and resources. In this study, an indicator system of URECC was built based on ecological civilization, which included 18 indicators chosen from 5 kinds of carrying capacities, which are water, land, atmospheric environment, energy, and solid waste. Then, the built index system was applied in a case study to evaluate URECC. Results showed that the indicator system could not only reveal the development tendency of URECC but also reveal changing situations of original bearing capacity, allowing the administration to take appropriate measures to improve URECC. Therefore, it can be guaranteed that economic and social development does not exceed URECC. It provides a good basis for building a more scientific, accurate, and comprehensive future assessment indicator system and also provides guidance and reference for rapid urban development. Consequently, this method not only addresses deficiencies in the existing researches but also provides a new method for assessing URECC.

[Sunshine environment in different forms of communities in Guiyang, China.] / è´µé˜³å¸‚ä¸åŒå½¢æ€ä½åŒºçš„æ—¥ç §çŽ¯å¢ƒ.

In this study, six different types of residential areas in Guiyang were selected as the research objects, including high-rise high-density, high-rise low-density, middle-rise high-density, middle-rise low-density, low-rise high-density and low-rise low-density. The indices of sunshine compliance rate and the building's sunshine hour ratio were constructed to compare and analyze sunshine environment across those six different residential areas. The factors influencing sunshine environment in different residential areas were studied. The results showed that the average sunshine compliance rates of the six types of residential areas were 36.9%, 61.9%, 20.6%, 69.6%, 26.5% and 45.0%, respectively. The average sunshine compliance rate of low-density residential areas was 2.25 times higher than that of high-density residential areas within the same type, among which the sunshine environment of low-density residential areas was better. The sunshine environment of different types of low-density residential areas was different. The sunshine hours for high-rise low-density and middle-rise low-density forms were concentrated in 5-6 hours, while the building's sunshine hour ratio was 0.24 and 0.32, respectively. The sunshine hours for low-rise low-density forms were mainly 6-7 hours, with a building's sunshine hour ratio of 0.28. Compared with other types of residential areas, the low-rise low-density type of sunlight environment was the best. The plot ratio was significantly positively correlated with the building's sunlight ratio of 0-1 h sunlight hours in the residential area.

Comprehensive evaluation for sustainable development based on relative resource carrying capacity-a case study of Guiyang, Southwest China.

On the basis of resource carrying capacity, this study used the revised theory of relative resource carrying capacity, took Guiyang as the study object, and calculated relative carrying capacities of natural resources, economic resources, environmental resources, and social resources from 2003 to 2017. Natural resources were composed of three indicators (energy resources, water resources, and land resources). Human capital resources were incorporated into social resources. Therefore, on the basis of the revised model of relative resource carrying capacity, conclusions were drawn: when taking the whole country as the reference area, Guiyang had an overloaded population from 2003 to 2017 whether under traditional or improved resource-carrying capacity model. But there were different results from these two models. When taking the entire province as the reference area, the result was the opposite. Whether taking the whole country or the entire province as the reference area, contributions of economic resources and social resources to comprehensive resource-carrying capacity were obviously higher than that of natural resources and environmental resources. When taking Guizhou as the reference area, other districts and counties were in the state of surplus, except that Qingzhen was overloaded after 2010 and Xiuwen was overloaded in 2010, 2011, and 2012. Therefore, corresponding countermeasures on sustainable development of Guiyang had been put forward in this study. It is necessary to control the population size, increase the cultivated land resources properly, accelerate regional economic development, strengthen ecological environmental protection, and save energy resources.

Comprehensive evaluation on water resource carrying capacity in karst areas using cloud model with combination weighting method: a case study of Guiyang, southwest China.

It is important to maintain the sustainable development of water resources. Objective assessment on water resource carrying capacity (WRCC) is beneficial to the formulation of scientific and reasonable water management practices. In view of the problem that evaluation indicators of WRCC cannot describe the fuzziness and randomness, a cloud model was introduced into regional WRCC assessment. This study selected a typical karst area (Guiyang) as the research object to study WRCC by using cloud model with combination weighting method. WRCC was assessed from the following five dimensions: water environment subsystem, social subsystem, economic subsystem, ecological subsystem, and humanities (water resource management and policy regulation) subsystem. In addition, evaluation results after normalizing all of indicators data were also calculated. And these two kinds of evaluation results were compared with that of technique of order preference similarity to the ideal solution (TOPSIS), finding that evaluation results of cloud model were consistent with that of TOPSIS method. The cloud model realizes the transformation from qualitative evaluation to quantitative evaluation, which overcome insufficiencies of traditional evaluation methods in considering fuzziness and randomness. Results showed that during the period of 2008-2017, the state of WRCC in Guiyang was improving year by year, increasing from the serious overload carrying capacity level in 2008 to the strong carrying capacity level in 2017 (serious overload-overload-critical-weak carrying capacity-strong carrying capacity). However, some certain evaluation indicators are still in danger situation, such as population natural growth rate and use of the fertilizer per unit cultivated area, which needs to be further enhanced and improved. Moreover, the contradiction among economic development, population growth, and water resources is becoming increasingly apparent. To ensure the effective utilization of water resources in Guiyang, reasonable policies and measures should be formulated and put into effect. Research results could provide certain reference for the sustainable development of regional water resources.

Seasonal Variation and Quality Assessment of the Major and Trace Elements of Atmospheric Dust in a Typical Karst City, Southwest China.

Atmospheric dust plays an important role in bio-geochemical cycling and the ecological environment. In urban areas, atmospheric dust is more likely to be the carrier of pollutants, thus affecting the air quality of cities. In this study, samples of atmospheric dust were collected monthly for one year in Guiyang City, and the contents of major and trace elements in the dust were determined. The results showed that the major and trace elements in the atmospheric dust of Guiyang city vary with the seasons. The concentrations of trace elements in the dust of autumn and winter were significantly higher than those in spring and summer. Most of the major elements in dust were higher than those in the corresponding topsoil, while most trace elements were similar to those in the topsoil except for Pb. The enrichment factor (EF) values calculated by topsoil as background showed that the Ca and Pb have higher EF values than the rest elements, indicating that some dust may be contaminated by Ca and Pb. The high content of Ca in the dust might be derived from concrete buildings in urban areas, while Pb might be closely related to motor vehicle emissions. The relationship between La and Yb of the atmospheric dust showed that the dust in Guiyang have the same pattern as those of Libo, it also revealed that these dust probably come mainly from natural sources and are less affected by human activities.

[Temporal Response of Subterranean Karst Stream Hydrochemistry to Urbanization].

The hydrochemical responses of underground rivers to urbanization were studied using a 25-year groundwater observation dataset and remote sensing. We found that as urbanization progresses, the mineralization degree of underground rivers gradually increases; time-series data for dominant hydrochemical indicators changed from HCO3·SO4-Ca·Mg during the dry season and HCO3-Ca·Mg during flood season to HCO3·Cl-Ca, HCO3·SO4-Ca, HCO3-Ca, and HCO3·SO4-Ca·Mg. Influenced by surface precipitation input, the groundwater chemistry of underground rivers varies greatly during the dry season and the flood season. Prior to urbanization,[Mg2+]/[Ca2+] and[HCO3-]/[SO42-] molar ratios are affected by water-rock interactions, agricultural activities, and acid rain infiltration, the average values of which were 0.86 and 29.34, respectively. After urbanization, agricultural activities and the contribution from acid rain decreased gradually. During the periods 1990-1995, 1996-2010, and 2011-2015, the main sensitive geochemical cations were Ca2+, Mg2+, Na+, and NH4+, and the main anions were HCO3-, HCO3-, and SO42-, and Cl-. The hydrochemical response of underground rivers to urbanization was characterized by clear temporal phases.

Drug resistance and genetic diversity of clinical strains of Helicobacter pylori in the Qiannan Prefecture and Guiyang City,and their relationships with diseases / 中国人兽共患病学报

To understand Helicobacter pylori's drug resistance,genetic diversity,and relationship with clinical diseases in the Guiyang and Qiannan minority areas of Guizhou Province,we collected samples through endoscopy,and isolated and cul-tured H.pylori.The drug resistance and genotype characteristics were determined.The differences in different regions and dis-ease types were compared,and the structural characteristics of H.pylori and mixed infections with different strains of H.py-lori in Qiannan Prefecture were analyzed.A difference in the composition ratio of EPYIA typing in the cagA variable region was observed between the two areas(P=0.012),and the composition ratio of the vacA genotype differed(P=0.000).A total of 94.6％(53/56)new sequences of H.pylori strains from two regions were obtained by MLST.The rate of infection by H.pylori mixed with different strains was 44.4％in Qiannan Pre-fecture,and no significant difference was observed in the com-position of H.pylori mixed infections among patients with dif-ferent clinical diseases(P=0.349).Differences in EPI YA typ-ing and the vacA genotype composition ratio in the cagA varia-ble region of H.pylori were observed between the Qiannan Prefecture and Guiyang City.

Study on the spatial distribution and related factors of medical insurance designated retail pharmacies in Guiyang / 中国药房

OBJECTIVE To pr ovide theoretic support for Guiyang to scientifically guide the development of drug retail industry and implement national health policies . METHODS The data were collected through statistical yearbook ，data cloud ， coordinate acquisition device of Application Programming Interface of Baidu map and so on. The spatial distribution characteristics and accessibility of medical insurance designated retail pharmacies （shorted for “designated pharmacies ”）in Guiyang were analyzed by spatial analysis based on Geographic Information System. The related factors for the distribution of designated pharmacies in Guiyang were analyzed by statistical method. RESULTS The number of designated pharmacies ，designated pharmacies per thousand people and designated pharmacies per 10 km2 in Guiyang increased from 2 018，0.41 and 2.51 in 2020 to 2 500，0.42 and 3.11 in 2021，with growth rates of 23.89％，2.44％ and 23.90％ respectively. The service area of the designated pharmacies that residents of Guiyang reached within 15 minutes on foot was 10.27％ of the total service area of designated pharmacies in Guiyang. The results of correlation analysis showed that the correlation coefficients between the regional gross regional production ，total retail sales of consumer goods ，population，urban per capita disposable income and the number of designated pharmacies in Guiyang were 0.999，0.999，0.977 and 0.992，respectively （all P＜0.05）. CONCLUSIONS The distribution of designated pharmacies is insufficient in Guiyang ，the development of designated pharmacies in various administrative regions is uneven ，and the layout of pharmacies is significantly affected by economic and demographic factors. It is suggested that the local government should explore the strategy of scientifically and reasonably expanding the coverage of designated pharmacies in urban and rural areas，promote the rational layout of pharmacies with appropriate economic and demographic policies ，and pay attention to improving the service capacity of designated pharmacies ，so as to improve the quality of life of the people and guide the healthy and high-quality development of drug retail industry.

Enterobius vermicularis infection in Guiyang City, Guizhou Province: a case report / 中国血吸虫病防治杂志

The report presents a case with Enterobius vermicularis infections in Guiyang City, Guizhou Province, aiming to strengthen the attention to parasitic infections.

[Level and the Courses of Heavy Metals and Its Risk Assessment in Indoor Dust of City: Take Guiyang as a Case].

A total of 73 household dust and 6 office dust were collected and the concentrations of Ca, Fe, Cd, Cr, Cu, Ni, Pb and Zn were measured by ICP-OES, in order to study the levels of heavy metals in city indoor dust and assessits risk from indoor and outdoor dust to children. The result showed that: 1 The concentrations of Ca, Fe were 107, 31.9 g·kg-1 and those of Cd, Cr, Cu, Ni, Pb and Zn were 1.77, 107, 231, 81.9, 199, 721 mg·kg-1, respectively. 2The levels of Cu and Zn in office dust were significantly higher than those in household dust, and the levels of other elements had no obvious difference from those in household dust. 3The levels of Ca and Fe in household dust with different floor numbers were not significantly different, but the levels of Cd, Cu and Pb in household dust with different floor numbers had obvious difference. The levels of elements in household dust from 1th floor were relatively higher, and the level of Pb in household dust from higher floors was higher than that on lower floors. 4Outdoor environment, indoor decoration and life styles may cause the difference of elements level in different household dust. 5There was no obvious risk from heavy metals in dust to children.