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1.
Sensors (Basel) ; 24(12)2024 Jun 14.
Artigo em Inglês | MEDLINE | ID: mdl-38931654

RESUMO

Conveyor belts serve as the primary mode of ore transportation in mineral processing plants. Feeders, comprised of shorter conveyors, regulate the material flow from silos to longer conveyor belts by adjusting their velocity. This velocity manipulation is facilitated by automatic controllers that gauge the material weight on the conveyor using scales. However, due to positioning constraints of these scales, a notable delay ensues between measurement and the adjustment of the feeder speed. This dead time poses a significant challenge in control design, aiming to prevent oscillations in material levels on the conveyor belt. This paper contributes in two key areas: firstly, through a simulation-based comparison of various control techniques addressing this issue across diverse scenarios; secondly, by implementing the Smith predictor solution in an operational plant and contrasting its performance with that of a single PID controller. Evaluation spans both the transient flow rate during step change setpoints and a month-long assessment. The experimental results reveal a notable increase in production by 355 t/h and a substantial reduction in flow rate oscillations on the conveyor belt, evidenced by a 55% decrease in the standard deviation.

2.
J Radiol Prot ; 44(2)2024 Apr 04.
Artigo em Inglês | MEDLINE | ID: mdl-38530296

RESUMO

Calibration of 22 gamma camera units was performed at 15 hospitals in southern and western Sweden to estimate137Cs contamination in humans in a supine static geometry, with a new developed calibration protocol and phantom. The minimum detectable activities (MDAs) and the estimated committed effective doses (CEDs) were calculated for each calibration. Generic calibration factors were calculated for five predetermined groups based on the detector type and manufacturer. Group 1 and 2 included NaI-based gamma cameras from General Electrics (GEs) with a crystal thickness of 5/8'' and 3/8'' respectively. Group 3 and 4 included NaI-based gamma cameras from Siemens Healthineers with a crystal thickness of 3/8'', with a similar energy window as the GE NaI-based cameras and a dual window respectively. Group 5 included semiconductor-based gamma cameras from GE with a CdZnTe (CZT) detector. The generic calibration factors were 60.0 cps kBq-1, 52.3 cps kBq-1, 50.3 cps kBq-1, 53.2 cps kBq-1and 48.4 cps kBq-1for group 1, 2, 3, 4, and 5 respectively. The MDAs ranged between 169 and 1130 Bq for all groups, with measurement times of 1-10 min, corresponding to a CED of 4.77-77.6µSv. A dead time analysis was performed for group 1 and suggested a dead time of 3.17µs for137Cs measurements. The dead time analysis showed that a maximum count rate of 232 kcps could be measured in the calibration geometry, corresponding to a CED of 108-263 mSv. It has been shown that semiconductor-based gamma cameras with CZT detectors are feasible for estimating137Cs contamination. The generic calibration factors derived in this study can be used for gamma cameras of the same models in other hospitals, for measurements in the same measurement geometry. This will increase the measurement capability for estimating internal137Cs contamination in the recovery phase following radiological or nuclear events.


Assuntos
Cádmio , Radioisótopos de Césio , Câmaras gama , Telúrio , Zinco , Humanos , Calibragem
3.
J Radiol Prot ; 2024 Sep 24.
Artigo em Inglês | MEDLINE | ID: mdl-39317230

RESUMO

Following a radiological or nuclear (RN) event, rapid measurement of131I in members of the public is of utmost importance, and much equipment is needed for a high throughput. In this study, three gamma cameras, two thyroid uptake meters and one whole-body counter were calibrated for activity measurements of131I in the thyroid. Minimum detectable activity was derived for the gamma cameras, the thyroid uptake meters and the whole-body counter giving that a committed effective dose (CED) in the interval 2.0-85 µSv, 13-700 µSv and 0.52-6.4 µSv, and thyroid absorbed doses in the interval 0.075-2.1 mGy, 0.48-17 mGy, and 0.020-0.15 mGy, respectively, can be assessed for children, adolescents, and adults. These numbers are based on 10-min measurement, performed at 1, 3 and 7 days after intake, and the CED includes intake by ingestion and inhalation of aerosols Type F, with an activity median aerodynamic diameter (AMAD) of 1 µm. For a fractional signal loss of 63% due to dead time, a CED up to 2.0, 84 and 3.6 Sv and thyroid absorbed dose up to 47 Gy, 2000 Gy and 88 Gy for the three systems, respectively, can be assessed for children and intake by ingestion as a worst-case scenario in terms of CED, measured 7 days after intake. This study demonstrates the potential and limitations of using equipment readily available at larger hospitals for estimation of131I content in thyroid, which could increase the measurement capability following an RN event. .

4.
Microsc Microanal ; 29(3): 1096-1110, 2023 Jun 09.
Artigo em Inglês | MEDLINE | ID: mdl-37749698

RESUMO

Observed photon count rates must be corrected for detector dead time effects for accurate quantification, especially at high count rates. We present the "constant k-ratio" method, a new approach for calibrating dead time for wavelength dispersive spectrometers by measuring k-ratios as a function of beam current. The method is based on the observation that for a given emission line at a specific take-off angle and electron beam energy, the intensity ratio from two materials containing the element should remain constant as a function of beam current, if the dead time calibration is accurate. The method has the advantage that it does not rely on the linearity of the beam current picoammeter, yet also allows the analyst to evaluate the picoammeter linearity, another critical parameter in EPMA calibration. By simultaneously comparing k-ratios for all spectrometers, one can also ascertain k-ratio consensus, essential for inter-laboratory comparisons. We also introduce improved dead time expressions and provide best practices on how to perform these instrument calibrations using this new "constant k-ratio" method. These improvements enable quantitative analysis of major and minor elements with high accuracy at high beam currents, simultaneously with trace elements with high sensitivity, for point analyses and X-ray mapping.

5.
Magn Reson Med ; 87(3): 1360-1374, 2022 03.
Artigo em Inglês | MEDLINE | ID: mdl-34775617

RESUMO

PURPOSE: To overcome limitations in the duration of RF excitation in zero-TE (ZTE) MRI by exploiting intrinsic encoding properties of RF pulses to retrieve data missed during the dead time caused by the pulse. METHODS: An enhanced ZTE signal model was developed using multiple RF pulses, which enables accessing information hidden in the pulse-induced dead time via encoding intrinsically applied by the RF pulses. Such ZTE with pulse encoding was implemented by acquisition of two ZTE data sets using excitation with similar frequency-swept pulses differing only by a small off-resonance in their center frequency. In this way, the minimum scan time is doubled but each acquisition contributes equally to the SNR, as with ordinary averaging. The method was demonstrated on long-T2 and short-T2 phantoms as well as in in vivo experiments. RESULTS: ZTE with pulse encoding provided good image quality at unprecedented dead-time gaps, demonstrated here up to 6 Nyquist dwells. In head imaging, the ability to use longer excitation pulses led to approximately 2-fold improvements in SNR efficiency as compared with conventional ZTE and allowed the creation of T1 contrast. CONCLUSION: Exploiting intrinsic encoding properties of RF pulses in a new signal model enables algebraic reconstruction of ZTE data sets with large dead-time gaps. This permits larger flip angles, which can be used to achieve enhanced T1 contrast and significant improvements in SNR efficiency in case the Ernst angle can be better approached, thus broadening the range of application of ZTE MRI.


Assuntos
Algoritmos , Imageamento por Ressonância Magnética , Frequência Cardíaca , Imagens de Fantasmas
6.
Biotechnol Lett ; 44(3): 415-427, 2022 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-35092530

RESUMO

OBJECTIVES: To obtain a mathematical model that adequately describes the time lag between biomass generation and lactic acid production of lactic fermentations. METHODS: Seven experimental kinetics from other research works were studied to validate our proposal: four studies of Fungal Submerged Fermentation and three cases of Bacterial Submerged Fermentation, including the data recollected by Luedeking and Piret. RESULTS: We introduce a modification to the Luedeking and Piret model that consist in the introduction of a time delay parameter in the model, this parameter would account for the lag time that exists between the production of biomass and lactic acid. It is possible to determine this time delay in a simple way by approximating the biomass and product formation considering that they behave as a first order plus dead time system. The duration of this phenomenon, which is not described with the classical Luedeking and Piret model, is a function of microorganism physiology (ease of biomass growth), environment (nutrients) and type of inoculum. CONCLUSION: The Luedeking and Piret with delay model applications reveal an increase of the R2 in all cases, evidencing the quality of fit and the simplicity of the method proposed. These model would improve the accuracy of bioprocess scaling up.


Assuntos
Biotecnologia , Ácido Láctico , Biomassa , Fermentação , Cinética , Modelos Biológicos
7.
Sensors (Basel) ; 22(2)2022 Jan 13.
Artigo em Inglês | MEDLINE | ID: mdl-35062578

RESUMO

This paper proposes a novel hybrid arithmetic-trigonometric optimization algorithm (ATOA) using different trigonometric functions for complex and continuously evolving real-time problems. The proposed algorithm adopts different trigonometric functions, namely sin, cos, and tan, with the conventional sine cosine algorithm (SCA) and arithmetic optimization algorithm (AOA) to improve the convergence rate and optimal search area in the exploration and exploitation phases. The proposed algorithm is simulated with 33 distinct optimization test problems consisting of multiple dimensions to showcase the effectiveness of ATOA. Furthermore, the different variants of the ATOA optimization technique are used to obtain the controller parameters for the real-time pressure process plant to investigate its performance. The obtained results have shown a remarkable performance improvement compared with the existing algorithms.


Assuntos
Algoritmos
8.
Biol Cybern ; 115(2): 177-190, 2021 04.
Artigo em Inglês | MEDLINE | ID: mdl-33742314

RESUMO

The inhomogeneous Poisson point process is a common model for time series of discrete, stochastic events. When an event from a point process is detected, it may trigger a random dead time in the detector, during which subsequent events will fail to be detected. It can be difficult or impossible to obtain a closed-form expression for the distribution of intervals between detections, even when the rate function (often referred to as the intensity function) and the dead-time distribution are given. Here, a method is presented to numerically compute the interval distribution expected for any arbitrary inhomogeneous Poisson point process modified by dead times drawn from any arbitrary distribution. In neuroscience, such a point process is used to model trains of neuronal spikes triggered by the detection of excitatory events while the neuron is not refractory. The assumptions of the method are that the process is observed over a finite observation window and that the detector is not in a dead state at the start of the observation window. Simulations are used to verify the method for several example point processes. The method should be useful for modeling and understanding the relationships between the rate functions and interval distributions of the event and detection processes, and how these relationships depend on the dead-time distribution.


Assuntos
Neurônios , Distribuição de Poisson , Processos Estocásticos
9.
Sensors (Basel) ; 21(4)2021 Feb 09.
Artigo em Inglês | MEDLINE | ID: mdl-33572285

RESUMO

Magnetic nanoparticles (MNP) offer a large variety of promising applications in medicine thanks to their exciting physical properties, e.g., magnetic hyperthermia and magnetic drug targeting. For these applications, it is crucial to quantify the amount of MNP in their specific binding state. This information can be obtained by means of magnetorelaxometry (MRX), where the relaxation of previously aligned magnetic moments of MNP is measured. Current MRX with optically pumped magnetometers (OPM) is limited by OPM recovery time after the shut-off of the external magnetic field for MNP alignment, therewith preventing the detection of fast relaxing MNP. We present a setup for OPM-MRX measurements using a commercially available pulsed free-precession OPM, where the use of a high power pulsed pump laser in the sensor enables a system recovery time in the microsecond range. Besides, magnetometer raw data processing techniques for Larmor frequency analysis are proposed and compared in this paper. Due to the high bandwidth (≥100 kHz) and high dynamic range of our OPM, a software gradiometer in a compact enclosure allows for unshielded MRX measurements in a laboratory environment. When operated in the MRX mode with non-optimal pumping performance, the OPM shows an unshielded gradiometric noise floor of about 600 fT/cm/Hz for a 2.3 cm baseline. The noise floor is flat up to 1 kHz and increases then linearly with the frequency. We demonstrate that quantitative unshielded MRX measurements of fast relaxing, water suspended MNP is possible with the novel OPM-MRX concept, confirmed by the accurately derived iron amount ratios of MNP samples. The detection limit of the current setup is about 1.37 µg of iron for a liquid BNF-MNP-sample (Bionized NanoFerrite) with a volume of 100 µL.


Assuntos
Nanopartículas de Magnetita , Campos Magnéticos , Magnetismo , Software
10.
J Synchrotron Radiat ; 27(Pt 6): 1609-1613, 2020 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-33147185

RESUMO

Under the condition of high counting rate, the phenomenon of nuclear pulse signal pile-up using a single exponential impulse shaping method is still very serious, and leads to a severe loss in counting rate. A real nuclear pulse signal can be expressed as a dual-exponential decay function with a certain rising edge. This paper proposes a new dual-exponential impulse shaping method and shows its deployment in hardware to test its performance. The signal of a high-performance silicon drift detector under high counting rate in an X-ray fluorescence spectrometer is obtained. The result of the experiment shows that the new method can effectively shorten the dead-time caused by nuclear signal pile-up and correct the counting rate.

11.
Entropy (Basel) ; 22(8)2020 Jul 30.
Artigo em Inglês | MEDLINE | ID: mdl-33286617

RESUMO

This paper studies the discrete-time Poisson channel and the noiseless binary channel where, after recording a 1, the channel output is stuck at 0 for a certain period; this period is called the "dead time." The communication capacities of these channels are analyzed, with main focus on the regime where the allowed average input power is close to zero, either because the bandwidth is large, or because the available continuous-time input power is low.

12.
J Synchrotron Radiat ; 26(Pt 5): 1621-1630, 2019 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-31490152

RESUMO

Modern photon-counting pixel detectors have enabled a revolution in applications at synchrotron light sources and beyond in the last decade. One of the limitations of the current detectors is their reduced counting linearity or even paralysis at high counting rates, due to dead-time which results in photon pile-up. Existing dead-time and pile-up models fail to reproduce the complexity of dead-time effects on photon-counting, resulting in empirical calibrations for particular detectors at best, imprecise linearization methods, or no linearization. This problem will increase in the future as many synchrotron light sources plan significant brilliance upgrades and free-electron lasers plan moving to a quasi-continuous operation mode. Presented here are the first models that use the actual behavior of the analog pre-amplifiers in spectroscopic photon-counting pixel detectors with constant current discharge (e.g. the Medipix and CPix families of detectors) to deduce more accurate analytical models and optimal linearization methods. In particular, for detectors with at least two counters per pixel, the need for calibration, or previous knowledge of the detector and beam parameters (dead-time, integration time, large sets of synchrotron filling patterns), is completely eliminated. This is summarized in several models of increasing complexity and accuracy. Finally, a general empirical approach is presented, applicable to any particular cases where the analytical approach is not sufficiently precise.

13.
Microsc Microanal ; 25(2): 418-424, 2019 04.
Artigo em Inglês | MEDLINE | ID: mdl-30757977

RESUMO

Due to the low capacity of contemporary position-sensitive detectors in atom probe tomography (APT) to detect multiple events, material analyses that exhibit high numbers of multiple events are the most subject to compositional biases. To solve this limitation, some researchers have developed statistical correction algorithms. However, those algorithms are only efficient when one is confronted with homogeneous materials having nearly the same evaporation field between elements. Therefore, dealing with more complex materials must be accompanied by a better understanding of the signal loss mechanism during APT experiments. By modeling the evaporation mechanism and the whole APT detection system, it may be possible to predict compositional and spatial biases induced by the detection system. This paper introduces a systematic study of the impact of the APT detection system on material analysis through the development of a simulation tool.

14.
Sensors (Basel) ; 19(14)2019 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-31311160

RESUMO

Dead time estimation is important in the design process of quartz flexure accelerometers. However, to the authors' knowledge, the dead time existing in quartz flexure accelerometers is not well investigated in conventional identification studies. In this paper, the dead time, together with the open-loop transfer function of quartz flexure accelerometers, is identified from step excitation experiments using two steps. Firstly, a monotonicity number was proposed to estimate the dead time. Analysis showed that the monotonicity number was robust enough to measurement noise and sensitive to step excitation. Secondly, parameters of the open-loop transfer function were identified using the least mean squares algorithm. A simulation example was applied to demonstrate the validity of the proposed method. The verified method was used to test a quartz flexure accelerometer. The experimental result shows that the dead time was 500 µs.

15.
Sensors (Basel) ; 20(1)2019 Dec 19.
Artigo em Inglês | MEDLINE | ID: mdl-31861695

RESUMO

This paper presents the design and experimental characterization of a 28 nm Complementary Metal Oxide Semiconductor (CMOS) Analog Front-End (AFE) for fast-tracking small-diameter Muon Drift-Tube (sMDT) detectors. The device exploits an innovative analog signal processing that allows a strong increase in the detection rate of events and significantly reduces the impact of fake/pile-up events, which often corrupt incident radiation energy events. The proposed device converts the input charge coming from incident radiations into voltage by a dedicated Charge-Sensitive Preamplifier (CSPreamp). Therefore, the fast-tracking concept relies on sampling the slope of the CSPreamp output voltage and using it for detecting both the incident event arrival instant and the amount of charge that has been effectively read out by MDT detectors. This avoids the long processing times intrinsically needed for baseline recovery transient, during which the detected signal can be severely corrupted by additional and unwanted extra-events, resulting in extra-charge (and thus in CSP output voltage extra-transient) during the signal roll-off. The proposed analog channel operates with a 5-100 fC input charge range and has a maximum dead-time of 200 ns (against the 545 ns of the state-of-the-art). It occupies 0.03 mm2 and consumes 1.9 mW from 1 V of supply voltage.

16.
J Synchrotron Radiat ; 25(Pt 2): 484-495, 2018 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-29488928

RESUMO

Dead-time effects in X-ray spectra taken with a digital pulse processor and a silicon drift detector were investigated when the number of events at the low-energy end of the spectrum was more than half of the total, at counting rates up to 56 kHz. It was found that dead-time losses in the spectra are energy dependent and an analytical correction for this effect, which takes into account pulse pile-up, is proposed. This and the usual models have been applied to experimental measurements, evaluating the dead-time fraction either from the calculations or using the value given by the detector acquisition system. The energy-dependent dead-time model proposed fits accurately the experimental energy spectra in the range of counting rates explored in this work. A selection chart of the simplest mathematical model able to correct the pulse-height distribution according to counting rate and energy spectrum characteristics is included.

17.
Magn Reson Med ; 79(4): 2036-2045, 2018 04.
Artigo em Inglês | MEDLINE | ID: mdl-28856717

RESUMO

PURPOSE: MRI of tissues with short coherence lifetimes T2 or T2* can be performed efficiently using zero echo time (ZTE) techniques such as algebraic ZTE, pointwise encoding time reduction with radial acquisition (PETRA), and water- and fat-suppressed proton projection MRI (WASPI). They share the principal challenge of recovering data in central k-space missed due to an initial radiofrequency dead time. The purpose of this study was to compare the three techniques directly, with a particular focus on their behavior in the presence of ultra-short-lived spins. METHODS: The most direct comparison was enabled by aligning acquisition and reconstruction strategies of the three techniques. Image quality and short- T2* performance were investigated using point spread functions, 3D simulations, and imaging of phantom and bone samples with short (<1 ms) and ultra-short (<100 µs) T2*. RESULTS: Algebraic ZTE offers favorable properties but is limited to k-space gaps up to approximately three Nyquist dwells. At larger gaps, PETRA enables robust imaging with little compromise in image quality, whereas WASPI may be prone to artifacts from ultra-short T2* species. CONCLUSION: For small k-space gaps (<4 dwells) and T2* much larger than the dead time, all techniques enable artifact-free short- T2* MRI. However, if these requirements are not fulfilled careful consideration is needed and PETRA will generally achieve better image quality. Magn Reson Med 79:2036-2045, 2018. © 2017 International Society for Magnetic Resonance in Medicine.


Assuntos
Processamento de Imagem Assistida por Computador/métodos , Imageamento por Ressonância Magnética , Algoritmos , Animais , Artefatos , Osso e Ossos/diagnóstico por imagem , Bovinos , Simulação por Computador , Humanos , Interpretação de Imagem Assistida por Computador , Imageamento Tridimensional , Modelos Teóricos , Imagens de Fantasmas , Polimetil Metacrilato/química , Prótons , Ondas de Rádio , Tíbia/diagnóstico por imagem
18.
J Synchrotron Radiat ; 22(5): 1190-201, 2015 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-26289270

RESUMO

Dead-time losses are well recognized and studied drawbacks in counting and spectroscopic systems. In this work the abilities on dead-time correction of a real-time digital pulse processing (DPP) system for high-rate high-resolution radiation measurements are presented. The DPP system, through a fast and slow analysis of the output waveform from radiation detectors, is able to perform multi-parameter analysis (arrival time, pulse width, pulse height, pulse shape, etc.) at high input counting rates (ICRs), allowing accurate counting loss corrections even for variable or transient radiations. The fast analysis is used to obtain both the ICR and energy spectra with high throughput, while the slow analysis is used to obtain high-resolution energy spectra. A complete characterization of the counting capabilities, through both theoretical and experimental approaches, was performed. The dead-time modeling, the throughput curves, the experimental time-interval distributions (TIDs) and the counting uncertainty of the recorded events of both the fast and the slow channels, measured with a planar CdTe (cadmium telluride) detector, will be presented. The throughput formula of a series of two types of dead-times is also derived. The results of dead-time corrections, performed through different methods, will be reported and discussed, pointing out the error on ICR estimation and the simplicity of the procedure. Accurate ICR estimations (nonlinearity < 0.5%) were performed by using the time widths and the TIDs (using 10 ns time bin width) of the detected pulses up to 2.2 Mcps. The digital system allows, after a simple parameter setting, different and sophisticated procedures for dead-time correction, traditionally implemented in complex/dedicated systems and time-consuming set-ups.

19.
Phys Med ; 119: 103298, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38309102

RESUMO

BACKGROUND: The dead-time loss reportedly degrades the accuracy of dosimetry using a gamma camera for targeted radionuclide therapy with Lu-177; therefore, the dead-time loss needs to be corrected. However, the correction is challenging. In this study, we propose a novel and simple method to shorten the apparent dead time rather than correcting it through experiments and Monte Carlo simulations. METHODS: An energy window of 208 keV ± 10 % is generally used for the imaging of Lu-177. Lower-energy gamma photons and X-rays of Lu-177 do not contribute to image formation but lead to dead-time losses. In our proposed method, a thin lead sheet was used to shield gamma photons and X-rays with energies lower than 208 keV, while detecting 208 keV gamma photons that penetrated the thin sheet. We measured and simulated the energy spectra and count rate characteristics of a clinical gamma camera system using a cylindrical phantom filled with a Lu-177 solution. Lead sheets of 1.0- and 0.5-mm thicknesses were used as thin shields, and the dead-time losses in tumour imaging with consumed Lu-177 were simulated. RESULTS: The apparent dead times with lead sheets of 1.0- and 0.5-mm thicknesses and without a lead sheet were 1.7, 1.9, and 5.8 µs for an energy window of 208 keV ± 10 %, respectively. The dead-time losses could be reduced from 10 % to 1.3 % using the 1.0-mm thick lead sheet in the simulated imaging of tumour. CONCLUSION: Our method is promising in clinical situations and studies on Lu-177 dosimetry for tumours.


Assuntos
Neoplasias , Radioisótopos , Humanos , Radioisótopos/uso terapêutico , Câmaras gama , Lutécio/uso terapêutico , Imagens de Fantasmas , Método de Monte Carlo
20.
Appl Radiat Isot ; 209: 111321, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38648701

RESUMO

In nuclear radiation detection, some measured radiation counts are lost due to dead time. Estimation of dead time is necessary to restore the counting information in quantitative analysis. This study aims to propose a method for estimating dead time at high counting rate. First of all, a measurement system of pulse interval distribution was used to estimate the true input counting rate of the detection system and implemented in FPGA. Then, a digital pole-zero cancellation technique was introduced in the measurement system to decrease the decay time constant of pulse. This was aimed at mitigating the impact of pile-up on the pulse interval distribution spectrum, especially at high counting rate. The feasibility of this measurement system at high counting rate was verified by the experimental platform of EDXRF. The dead time was calculated using the measured counting rate and the estimated true input counting rate. The accuracy of the dead time relies on the precision of the estimated true count rate. When the counting rate reaches 600 kCPS, the relative error between the theoretical counting rate and the estimated true input counting rate is less than 5%.

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