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1.
Sensors (Basel) ; 19(12)2019 Jun 14.
Artigo em Inglês | MEDLINE | ID: mdl-31208014

RESUMO

There are some special merits for the orthogonal frequency division multiplexing (OFDM)chirp waveform as multiple input multiple output (MIMO) signals. This signal has high rangeresolution, good Doppler tolerance, and constant modulus superiority since it exploits a fullbandwidth and is based on chirp signals. The correlation sidelobe peaks level are critical for thedetection requirement of MIMO radar signals, however conventional OFDM chirp signals producehigh autocorrelation sidelobe peaks (ASP) and cross-correlation peaks (CP), which reducesdetection performance. In this paper, we explore the structure of OFDM chirp signals'autocorrelation function and proposed a scheme to reduce the designed signal's ASP by a designingsuitable range of subchirp bandwidth and a segmented transmit-receive mode. Next, we explore asuitable range of interval between the chirp rates of each two signals to reduce the CP. Thesimulation of designed signals verifies the effectiveness of the proposed methods in the reductionof ASP and CP, with the correlation performance being compared with recent relate studies. Inaddition, the multiple signals detection and one-dimensional range image simulation show thegood detection performance of a designed signal in MIMO radar detection.

2.
J Magn Reson Imaging ; 46(6): 1728-1737, 2017 12.
Artigo em Inglês | MEDLINE | ID: mdl-28295824

RESUMO

PURPOSE: To assess the wavelet entropy for the characterization of intrinsic aberrant temporal irregularities in the time series of resting-state blood-oxygen-level-dependent (BOLD) signal fluctuations. Further, to evaluate the temporal irregularities (disorder/order) on a voxel-by-voxel basis in the brains of children with Rolandic epilepsy. MATERIALS AND METHODS: The BOLD time series was decomposed using the discrete wavelet transform and the wavelet entropy was calculated. Using a model time series consisting of multiple harmonics and nonstationary components, the wavelet entropy was compared with Shannon and spectral (Fourier-based) entropy. As an application, the wavelet entropy in 22 children with Rolandic epilepsy was compared to 22 age-matched healthy controls. The images were obtained by performing resting-state functional magnetic resonance imaging (fMRI) using a 3T system, an 8-element receive-only head coil, and an echo planar imaging pulse sequence ( T2*-weighted). The wavelet entropy was also compared to spectral entropy, regional homogeneity, and Shannon entropy. RESULTS: Wavelet entropy was found to identify the nonstationary components of the model time series. In Rolandic epilepsy patients, a significantly elevated wavelet entropy was observed relative to controls for the whole cerebrum (P = 0.03). Spectral entropy (P = 0.41), regional homogeneity (P = 0.52), and Shannon entropy (P = 0.32) did not reveal significant differences. CONCLUSION: The wavelet entropy measure appeared more sensitive to detect abnormalities in cerebral fluctuations represented by nonstationary effects in the BOLD time series than more conventional measures. This effect was observed in the model time series as well as in Rolandic epilepsy. These observations suggest that the brains of children with Rolandic epilepsy exhibit stronger nonstationary temporal signal fluctuations than controls. LEVEL OF EVIDENCE: 2 Technical Efficacy: Stage 3 J. Magn. Reson. Imaging 2017;46:1728-1737.


Assuntos
Mapeamento Encefálico/métodos , Encéfalo/diagnóstico por imagem , Encéfalo/fisiopatologia , Epilepsia Rolândica/diagnóstico por imagem , Epilepsia Rolândica/fisiopatologia , Imageamento por Ressonância Magnética/métodos , Criança , Entropia , Feminino , Humanos
3.
J Neurophysiol ; 113(10): 3798-815, 2015 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-25833839

RESUMO

During general anesthesia, global brain activity and behavioral state are profoundly altered. Yet it remains mostly unknown how anesthetics alter sensory processing across cortical layers and modulate functional cortico-cortical connectivity. To address this gap in knowledge of the micro- and mesoscale effects of anesthetics on sensory processing in the cortical microcircuit, we recorded multiunit activity and local field potential in awake and anesthetized ferrets (Mustela putoris furo) during sensory stimulation. To understand how anesthetics alter sensory processing in a primary sensory area and the representation of sensory input in higher-order association areas, we studied the local sensory responses and long-range functional connectivity of primary visual cortex (V1) and prefrontal cortex (PFC). Isoflurane combined with xylazine provided general anesthesia for all anesthetized recordings. We found that anesthetics altered the duration of sensory-evoked responses, disrupted the response dynamics across cortical layers, suppressed both multimodal interactions in V1 and sensory responses in PFC, and reduced functional cortico-cortical connectivity between V1 and PFC. Together, the present findings demonstrate altered sensory responses and impaired functional network connectivity during anesthesia at the level of multiunit activity and local field potential across cortical layers.


Assuntos
Vias Aferentes/fisiologia , Anestesia , Potenciais Evocados/fisiologia , Córtex Pré-Frontal/fisiologia , Córtex Visual/fisiologia , Vigília/fisiologia , Estimulação Acústica , Vias Aferentes/efeitos dos fármacos , Animais , Feminino , Furões , Estimulação Luminosa , Análise Espectral , Córtex Visual/efeitos dos fármacos
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