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Turk J Med Sci ; 50(SI-1): 549-556, 2020 04 21.
Artigo em Inglês | MEDLINE | ID: mdl-32293832

RESUMO

Coronaviruses (CoVs) cause a broad spectrum of diseases in domestic and wild animals, poultry, and rodents, ranging from mild to severe enteric, respiratory, and systemic disease, and also cause the common cold or pneumonia in humans. Seven coronavirus species are known to cause human infection, 4 of which, HCoV 229E, HCoV NL63, HCoV HKU1 and HCoV OC43, typically cause cold symptoms in immunocompetent individuals. The others namely SARS-CoV (severe acute respiratory syndrome coronavirus), MERS-CoV (Middle East respiratory syndrome coronavirus) were zoonotic in origin and cause severe respiratory illness and fatalities. On 31 December 2019, the existence of patients with pneumonia of an unknown aetiology was reported to WHO by the national authorities in China. This virus was officially identified by the coronavirus study group as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and the present outbreak of a coronavirus-associated acute respiratory disease was labelled coronavirus disease 19 (COVID-19). COVID-19's first cases were seen in Turkey on March 10, 2020 and was number 47,029 cases and 1006 deaths after 1 month. Infections with SARS-CoV-2 are now widespread, and as of 10 April 2020, 1,727,602 cases have been confirmed in more than 210 countries, with 105,728 deaths.


Assuntos
Betacoronavirus/fisiologia , Infecções por Coronavirus/epidemiologia , Coronavirus/classificação , Pneumonia Viral/epidemiologia , Enzima de Conversão de Angiotensina 2 , Animais , COVID-19 , China/epidemiologia , Coronavirus Humano 229E , Proteínas M de Coronavírus , Coronavirus Humano OC43 , Humanos , Coronavírus da Síndrome Respiratória do Oriente Médio , Proteínas do Nucleocapsídeo/química , Pandemias , Peptidil Dipeptidase A/química , Coronavírus Relacionado à Síndrome Respiratória Aguda Grave , SARS-CoV-2 , Glicoproteína da Espícula de Coronavírus/química , Turquia/epidemiologia , Proteínas da Matriz Viral/química , Montagem de Vírus , Internalização do Vírus
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