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There has been a recent surge of interest in incorporating fairness aspects into classical clustering problems. Two recently introduced variants of the k-Center problem in this spirit are Colorful k-Center, introduced by Bandyapadhyay, Inamdar, Pai, and Varadarajan, and lottery models, such as the Fair Robust k-Center problem introduced by Harris, Pensyl, Srinivasan, and Trinh. To address fairness aspects, these models, compared to traditional k-Center, include additional covering constraints. Prior approximation results for these models require to relax some of the normally hard constraints, like the number of centers to be opened or the involved covering constraints, and therefore, only obtain constant-factor pseudo-approximations. In this paper, we introduce a new approach to deal with such covering constraints that leads to (true) approximations, including a 4-approximation for Colorful k-Center with constantly many colors-settling an open question raised by Bandyapadhyay, Inamdar, Pai, and Varadarajan-and a 4-approximation for Fair Robust k-Center, for which the existence of a (true) constant-factor approximation was also open. We complement our results by showing that if one allows an unbounded number of colors, then Colorful k-Center admits no approximation algorithm with finite approximation guarantee, assuming that P ≠ NP . Moreover, under the Exponential Time Hypothesis, the problem is inapproximable if the number of colors grows faster than logarithmic in the size of the ground set.
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An instance of colorful k-center consists of points in a metric space that are colored red or blue, along with an integer k and a coverage requirement for each color. The goal is to find the smallest radius ρ such that there exist balls of radius ρ around k of the points that meet the coverage requirements. The motivation behind this problem is twofold. First, from fairness considerations: each color/group should receive a similar service guarantee, and second, from the algorithmic challenges it poses: this problem combines the difficulties of clustering along with the subset-sum problem. In particular, we show that this combination results in strong integrality gap lower bounds for several natural linear programming relaxations. Our main result is an efficient approximation algorithm that overcomes these difficulties to achieve an approximation guarantee of 3, nearly matching the tight approximation guarantee of 2 for the classical k-center problem which this problem generalizes. algorithms either opened more than k centers or only worked in the special case when the input points are in the plane.
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Wireless sensor network topology optimization is a highly important issue, and topology control through node selection can improve the efficiency of data forwarding, while saving energy and prolonging lifetime of the network. To address the problem of connecting a wireless sensor network to the Internet in cyber-physical systems, here we propose a geometric gateway deployment based on a competitive swarm optimizer algorithm. The particle swarm optimization (PSO) algorithm has a continuous search feature in the solution space, which makes it suitable for finding the geometric center of gateway deployment; however, its search mechanism is limited to the individual optimum (pbest) and the population optimum (gbest); thus, it easily falls into local optima. In order to improve the particle search mechanism and enhance the search efficiency of the algorithm, we introduce a new competitive swarm optimizer (CSO) algorithm. The CSO search algorithm is based on an inter-particle competition mechanism and can effectively avoid trapping of the population falling into a local optimum. With the improvement of an adaptive opposition-based search and its ability to dynamically parameter adjustments, this algorithm can maintain the diversity of the entire swarm to solve geometric K-center gateway deployment problems. The simulation results show that this CSO algorithm has a good global explorative ability as well as convergence speed and can improve the network quality of service (QoS) level of cyber-physical systems by obtaining a minimum network coverage radius. We also find that the CSO algorithm is more stable, robust and effective in solving the problem of geometric gateway deployment as compared to the PSO or Kmedoids algorithms.
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BACKGROUND AND OBJECTIVE: differential expression analysis is one of the most popular activities in transcriptomic studies based on next-generation sequencing technologies. In fact, differentially expressed genes (DEGs) between two conditions represent ideal prognostic and diagnostic candidate biomarkers for many pathologies. As a result, several algorithms, such as DESeq2 and edgeR, have been developed to identify DEGs. Despite their widespread use, there is no consensus on which model performs best for different types of data, and many existing methods suffer from high False Discovery Rates (FDR). METHODS: we present a new algorithm, DeClUt, based on the intuition that the expression profile of differentially expressed genes should form two reasonably compact and well-separated clusters. This, in turn, implies that the bipartition induced by the two conditions being compared should overlap with the clustering. The clustering algorithm underlying DeClUt was designed to be robust to outliers typical of RNA-seq data. In particular, we used the average silhouette function to enforce membership assignment of samples to the most appropriate condition. RESULTS: DeClUt was tested on real RNA-seq datasets and benchmarked against four of the most widely used methods (edgeR, DESeq2, NOISeq, and SAMseq). Experiments showed a higher self-consistency of results than the competitors as well as a significantly lower False Positive Rate (FPR). Moreover, tested on a real prostate cancer RNA-seq dataset, DeClUt has highlighted 8 DE genes, linked to neoplastic process according to DisGeNET database, that none of the other methods had identified. CONCLUSIONS: our work presents a novel algorithm that builds upon basic concepts of data clustering and exhibits greater consistency and significantly lower False Positive Rate than state-of-the-art methods. Additionally, DeClUt is able to highlight relevant differentially expressed genes not otherwise identified by other tools contributing to improve efficacy of differential expression analyses in various biological applications.
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Algoritmos , Perfilação da Expressão Gênica , Humanos , Análise por Conglomerados , Perfilação da Expressão Gênica/métodos , Transcriptoma , Neoplasias da Próstata/genética , Biologia Computacional/métodos , Masculino , Software , Sequenciamento de Nucleotídeos em Larga EscalaRESUMO
This study examines the concept of demand response in household appliance use. Its primary aim is to explore the factors influencing electricity consumption behavior and employ K-means clustering to group households, estimating daily electricity consumption patterns. This understanding is essential for the development of effective demand response strategies within the Greater Accra Region, Ghana. The research leveraged metrics, such as the Silhouette Score and principal component analysis to ensure the quality of the clustering process, effectively combining qualitative and quantitative data. Insights were enhanced by incorporating consumer behavior surveys to better comprehend appliance use trends and optimize demand response strategies. The findings emphasize differences in voltage, intensity, power consumption, and smart meter data among different household clusters. Notably, clusters 1 and 3 emerge as high energy consumers, particularly in water and cold appliances. These insights offer valuable guidance for targeted energy management and optimization strategies. This study underscores the significance of using consumer behavior insights to enhance and optimize demand response programs, providing essential guidance to energy stakeholders, particularly in Ghana, for the efficient optimization of electricity consumption and the successful implementation of demand response initiatives.
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The Non-Uniform k-center (NUkC) problem has recently been formulated by Chakrabarty et al. [ICALP, 2016; ACM Trans Algorithms 16(4):46:1-46:19, 2020] as a generalization of the classical k-center clustering problem. In NUkC, given a set of n points P in a metric space and non-negative numbers r 1 , r 2 , , r k , the goal is to find the minimum dilation α and to choose k balls centered at the points of P with radius α · r i for 1 ≤ i ≤ k , such that all points of P are contained in the union of the chosen balls. They showed that the problem is NP -hard to approximate within any factor even in tree metrics. On the other hand, they designed a "bi-criteria" constant approximation algorithm that uses a constant times k balls. Surprisingly, no true approximation is known even in the special case when the r i 's belong to a fixed set of size 3. In this paper, we study the NUkC problem under perturbation resilience, which was introduced by Bilu and Linial (Comb Probab Comput 21(5):643-660, 2012). We show that the problem under 2-perturbation resilience is polynomial time solvable when the r i 's belong to a constant-sized set. However, we show that perturbation resilience does not help in the general case. In particular, our findings imply that even with perturbation resilience one cannot hope to find any "good" approximation for the problem.