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1.
Microbiology (Reading) ; 170(2)2024 02.
Artigo em Inglês | MEDLINE | ID: mdl-38363121

RESUMO

Fifty years of research has transformed our understanding of bacterial movement from one of description, based on a limited number of electron micrographs and some low-magnification studies of cells moving towards or away from chemical effectors, to probably the best understood behavioural system in biology. We have a molecular understanding of how bacteria sense and respond to changes in their environment and detailed structural insights into the workings of one of the most complex motor structures we know of. Thanks to advances in genomics we also understand how, through evolution, different species have tuned and adapted a core shared system to optimize behaviour in their specific environment. In this review, I will highlight some of the unexpected findings we made during my over 40-year career, how those findings changed some of our understanding of bacterial behaviour and biochemistry and some of the battles to have those observations accepted.


Assuntos
Bactérias , Quimiotaxia , Bactérias/genética , Flagelos , Movimento
2.
Am J Med Genet A ; 194(6): e63514, 2024 06.
Artigo em Inglês | MEDLINE | ID: mdl-38329159

RESUMO

Genetics has become a critical component of medicine over the past five to six decades. Alongside genetics, a relatively new discipline, dysmorphology, has also begun to play an important role in providing critically important diagnoses to individuals and families. Both have become indispensable to unraveling rare diseases. Almost every medical specialty relies on individuals experienced in these specialties to provide diagnoses for patients who present themselves to other doctors. Additionally, both specialties have become reliant on molecular geneticists to identify genes associated with human disorders. Many of the medical geneticists, dysmorphologists, and molecular geneticists traveled a circuitous route before arriving at the position they occupied. The purpose of collecting the memoirs contained in this article was to convey to the reader that many of the individuals who contributed to the advancement of genetics and dysmorphology since the late 1960s/early 1970s traveled along a journey based on many chances taken, replying to the necessities they faced along the way before finding full enjoyment in the practice of medical and human genetics or dysmorphology. Additionally, and of equal importance, all exhibited an ability to evolve with their field of expertise as human genetics became human genomics with the development of novel technologies.


Assuntos
Genética Médica , Humanos , História do Século XX , História do Século XXI , Genética Humana
3.
Camb Q Healthc Ethics ; : 1-9, 2024 Oct 14.
Artigo em Inglês | MEDLINE | ID: mdl-39397764

RESUMO

This paper describes the content and evolution of a fourth-year course for medical students on teaching pathographies of mental illness. (It is a follow-up to Nathan Carlin's Pathographies of Mental Illness that appeared as an Element in the Bioethics and Neuroethics series published by Cambridge University Press.) The course originally centered on classic (and some contemporary) memoirs; however, responding to student evaluations, newer material now ensures more diversity, with material written by women and people of color, and describes the difference that can make.

4.
Nurs Inq ; 29(2): e12423, 2022 04.
Artigo em Inglês | MEDLINE | ID: mdl-34091998

RESUMO

Mary Livermore's My Story of the War is a valuable piece of travel writing written from the point of view of a nurse who documented her unexpected personal and professional journey to administer the Sanitary Commission of the United States Union Army and provide nursing care during the American Civil War. Although Livermore's pre-war background had not been solely limited to the domestic sphere, her wartime experience involved a public negotiation between the traditional domestic realm assigned to women and new nursing professional functions that emerged during the war. In a context in which the general access of women to public writing was rather limited and in which nursing was not a formally regulated professional activity, Livermore's triumphal narrative reflects the increasing connection between progressively professional nursing functions that emerged in the context of war and a new women's rights leadership forged during her autobiographical journey.


Assuntos
Guerra Civil Norte-Americana , Cuidados de Enfermagem , Feminino , Humanos , Narração , Estados Unidos , Direitos da Mulher , Redação
5.
Cult Med Psychiatry ; 45(1): 74-96, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-32124132

RESUMO

Child soldiers have been heavily involved in contemporary African warfare. Since the 1990s, the 'child soldier crisis' has become a major humanitarian and human rights project. The figure of the child soldier has often been taken as evidence of the 'barbarism', dehumanization and trauma generated by modern warfare, but such images can obscure the complex reality of children's experiences of being part of armed groups during conflict. This article uses the published memoirs of former child soldiers from Sierra Leone, Sudan, Uganda, Eritrea and the Democratic Republic of the Congo to explore the instrumental and discursive nexus between child soldiers, memory, violence and humanitarianism. It assesses how (former-) children combatants remember and recount their experiences of war, and how these narratives can be shaped by humanitarian, literary and/or therapeutic framings. The article argues that these memoirs' significance lies in their affective truths and what they reveal about children's experience, and narrations, of war. Former child soldiers engage with, but also challenge, dominant contemporary humanitarian discourses surrounding childhood and violence to develop a 'victim, savage, saviour, campaigner' framework for their narratives. The article historically contextualizes the emergence of the 'child soldier memoir', before analysing the narratives of recruitment, indoctrination, and violence recounted by these former child soldiers, and their attempts to rework their identities in a post-conflict environment. It explores how former child soldiers narrate suffering and deploy discourses of trauma in their memoirs: some seeking to process wartime traumas, others leveraging their own suffering to position themselves as campaigners for those children still caught in conflict.


Assuntos
Memória , Militares/psicologia , Violência/psicologia , Guerra , Ferimentos e Lesões/psicologia , Adolescente , África , Criança , Feminino , Humanos , Masculino
6.
J Lesbian Stud ; 25(3): 258-273, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-32657257

RESUMO

Saving Delaney is one of a number of "special needs" parent memoirs published in the United States since 2000 and is the only memoir about raising a disabled child in the United States written by lesbian parents. Like many representations of disability, "special needs" parent memoirs use a problematic narrative in which the presumed negative effects of disability are individually overcome before life lived happily ever after. Also like popular and positive representations of disability, the children subjects of "special needs" parent memoirs are almost entirely white. In this paper, I contextualize Saving Delaney within histories of lesbian, gay, bisexual, and transgender (LGBT) family-making in the United States, drawing particular attention to the overrepresentation of children with disabilities among gay and lesbian adoptive parent households. Then, drawing attention to the overwhelming whiteness of both positive portrayals of children with disabilities in "special needs" parent memoirs and LGBT families in scholarship, data, and media, I argue that white privilege facilitates visibility and protection against disability stigmas. I demonstrate that LGBT family-making and caring for children with disabilities cohere as issues of comprehensive reproductive justice and that narratives like Delaney's fail to advance the reproductive justice movement due to reiterative entrenchment in the material and discursive privileges of whiteness.


Assuntos
Crianças com Deficiência , Homossexualidade Feminina/psicologia , Mães/psicologia , Minorias Sexuais e de Gênero/psicologia , Adulto , População Negra/psicologia , Criança , Cuidado da Criança , Família , Feminino , Humanos , Literatura Moderna , Estados Unidos , População Branca/psicologia
7.
J Lesbian Stud ; 25(1): 18-35, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-31809661

RESUMO

We argue that historical femme life writing forms a rich resource for femme theory that contributes to, challenges, and extends contemporary academic femme literature. We focus on the experiences of femmes during the second-wave feminist movement, specifically within the context of 1970s and 1980s U.S. lesbian feminism. The texts we examine include My Dangerous Desires by Amber Hollibaugh (2000), A Restricted Country by Joan Nestle (1987), Minnie Bruce Pratt's (1995) S/he, and selections from The Persistent Desire: A Femme-Butch Reader, edited by Nestle (1992). Informed by Clare Hemmings' (2011) and Victoria Hesford's (2013) critiques that past feminisms are often retold using reductive narratives, we (re)read this femme life writing to foreground the ways in which femmes have historically troubled and resisted monolithic accounts of lesbian feminism, lesbian identities, femininity, and sexuality. By centering queer feminine voices from this period to highlight major themes of this life writing, and drawing on Andi Schwartz's (2018) positioning of femme cultural production as a basis for theory, we argue that earlier iterations of queer femininities are relevant to and important for contemporary femme theory. Ultimately, we analyze what historical femme life writing reveals about the place of femininity within the lesbian and feminist communities of their time, how these dynamics inform current perceptions of queer and femme politics, and how femmes resist their cultural and critical marginalization.


Assuntos
Feminilidade , Literatura/história , Teoria Psicológica , Literatura Erótica , Feminino , Feminilidade/história , Feminismo/história , História do Século XX , Homossexualidade Feminina , Humanos , Narração , Fatores Raciais , Minorias Sexuais e de Gênero , Identificação Social , Redação
9.
J Clin Psychol ; 71(11): 1049-59, 2015 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-26378375

RESUMO

This introduction to this issue of JCLP: In Session ("Reflections of Senior Therapists") focuses on the multifaceted ways in which adult development influences what it means to be a psychotherapist and to do the work of psychotherapy. This issue brings together first person narratives written by a group of eminent psychotherapists as well as an empirical report, based on a major international survey, on the challenges, demands, and rewards experienced by senior therapists. Taken together, these essays provide a compelling case that not only can practicing psychotherapy during the later years of one's life continue to be fulfilling and meaningful, but also the lessons learned along the journey can make one an even wiser and more effective therapist than previously. Learning to do psychotherapy, like adult development itself, is not a process that at some point comes to an end, but one that is resumed again and again in every decade. These essays provide a rich array of information, insight, and guidance regarding the personal and professional experience of practicing therapy during every era of adulthood, including one's senior years.


Assuntos
Envelhecimento/psicologia , Pessoal de Saúde/psicologia , Narrativas Pessoais como Assunto , Psicoterapia , Idoso , Humanos
10.
J Lesbian Stud ; 19(1): 27-34, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25575319

RESUMO

This article reports on a federally funded research project in which old lesbians were invited to separate out and examine the complicated strands of lives lived through times of great social change-times in which notions of "woman," "sexuality," and "subjectivity" have been both over- and under-determined by dominant discourse (Stein, 1997). We argue, with Haug (1992), that close attention to the personal is central to critical feminist perspectives and that writers can become more aware of normalizing cultural influences when they pay close attention to language. In this article, we support our position with a case study of one participant in our "language school" (Haug, 1992). As we analyzed her written life narratives and oral testimony, we conclude that she was able to reconsider comfortable "coming out" narratives in order to construct new meaning and to challenge her understandings of the past.


Assuntos
Feminismo , Homossexualidade Feminina , Mudança Social , Mulheres , Feminino , Humanos , Percepção Social
11.
Gerontologist ; 64(6)2024 06 01.
Artigo em Inglês | MEDLINE | ID: mdl-38150319

RESUMO

BACKGROUND AND OBJECTIVES: The complexities surrounding aging, dementia, and care are timely issues that transcend beyond institutional boundaries, evincing a critical debate on later life across disciplines. The aim of this study is to offer fresh insights into the intricate paradigms of living and growing older with dementia. The study focuses on the Nobel Prize-winning author Annie Ernaux's memoir I Remain in Darkness (1999), which provides a candid account of her mother's journey through dementia from its onset to the gradual decline. RESEARCH DESIGN AND METHODS: This article employs the theoretical frameworks of literary gerontology, illness narratives and life writing to address the challenges of aging, dementia and care that are represented in Ernaux's memoir. It also addresses societal attitudes and stigma associated with aging and dementia by exploring the embarrassment that individuals and families experience when confronted with the deteriorating mental health of their loved ones. RESULTS: Ernaux's memoir explores the nuances of dementia and caregiving within both the familial and institutional context, and sheds light on the complex relationship between a mother and a daughter. Through the act of witnessing, Ernaux embarks on a path of healing, which allows her to confront her past wounds and better navigate the challenges that lie ahead. However, Ernaux's confessional memoir also troubles the ethics of life writing and identity issues, and seems to perpetuate the pathologizing medical gaze through the exposure of her mother's vulnerability and intimacy in the face of dementia and care. DISCUSSION AND IMPLICATIONS: Ernaux's account of her mother's dementia and aging is both a confessional piece of writing and a narrative therapy, which reveals the challenges of aging, illness, and unresolved family tensions. Her work illuminates the interconnectedness between the past, present, and future, and shows that illness narratives can act as a catalyst for transformative change, identity formation, and self-reflection. The article addresses the intricacies of old age, showcasing how life writing and humanities-based inquiry can bring to the fore key aspects of the latest stages in life, which are often unvoiced because they represent the most unpleasant and feared aspects of aging in contemporary society.


Assuntos
Cuidadores , Demência , Humanos , Demência/psicologia , Feminino , Cuidadores/psicologia , Envelhecimento/psicologia , Idoso
12.
J Med Humanit ; 2024 Jul 22.
Artigo em Inglês | MEDLINE | ID: mdl-39037561

RESUMO

This article examines two autobiographical texts that address the relationship between migration and struggles with mental health: Karla Cornejo Villavicencio's The Undocumented Americans (2021) and Dina Nayeri's The Ungrateful Refugee: What Immigrants Never Tell You (2020). Both memoirs help bring mental health issues to light in situations of precarity, and the texts indicate that it is not just the experience of physical dislocation that may cause or exacerbate struggles with mental health, but the disconnect from other people, from citizenship, and the nation itself. Nayeri and Cornejo Villavicencio do not focus on narratives of recovery or healing but provide space for the experiences of other undocumented migrants trying to navigate the European asylum system or difficulties in obtaining American citizenship. The article argues that the two authors use their experiences of migration and mental illness for greater advocacy purposes with regard to human rights. The struggles with mental health present in the two memoirs intertwine with the treatment of undocumented migrants as described by the two authors, going beyond the personal experience of mental health, or illness, connecting it with migration practices and policies in the United States and Europe.

13.
Cureus ; 16(9): e68832, 2024 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-39376811

RESUMO

Dr. John H. Charnley (1924-1982) revolutionized orthopedic surgery with his groundbreaking innovations in hip replacement with exceptional skill and a holistic thought process, which has had an impact to this day in the world of arthroplasty. His innovations have improved the lives of numerous patients who had painful and discomforting arthritis and have been instrumental in providing painless mobile joints to these patients. This article reviews Charnley's contributions to the development of low-friction arthroplasty using ultra-high-molecular-weight polyethylene and the use of acrylic bone cement for improved implant fixation. These advancements dealt with the critical issues of friction, wear, and implant stability, significantly enhancing patient outcomes and implant longevity. Charnley's work led to the global standardization of hip replacement procedures, influencing orthopedic practices globally and setting benchmarks for modern implant designs. His principles continue to inform ongoing research and advancements in hip replacement technology. This review also discusses the challenges and criticisms faced by Charnley's innovations, reflecting on their evolution and impact on contemporary orthopedic surgery. A surgeon blessed with a noble heart who would help his patients who were in trouble by going out of the way and was determined for a better tomorrow, self-driven by his compassion and ambition for treating his patients. Charnley's legacy remains pivotal in shaping the field and improving the quality of life for patients undergoing hip replacement surgery.

14.
Curr Opin Psychol ; 50: 101557, 2023 04.
Artigo em Inglês | MEDLINE | ID: mdl-36805288

RESUMO

It is not yet clear how nostalgia achieves the wide-ranging benefits on wellbeing documented by research. Much of the research favorable to nostalgia has employed experimental and quantitative methods within a laboratory setting. Literature and memoir offer a wider range of content for exploration into the complexity of nostalgia. Literature, memoir, and laboratory research have all illustrated the role of nostalgia in sustaining meaning, identity, and social connectedness. However, initial insights from this appraisal suggest a stronger emphasis in literary forms on the role of nostalgia in resolving conflict and coping with change and loss. Literary forms supplement laboratory efforts by providing a greater diversity of life experience and reflections that can yield more integrative syntheses over time.


Assuntos
Adaptação Psicológica , Acontecimentos que Mudam a Vida , Humanos
15.
J Med Biogr ; 31(3): 202-211, 2023 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-34081544

RESUMO

In the Second World War, there was a flowering of the battlefield surgery pioneered in the Spanish Civil War. There were small, mobile surgical units in all the theatres of the War, working close behind the fighting and deployed flexibly according to the nature of the conflict. With equipment transported by truck, jeep or mule, they operated in tents, bunkers and requisitioned buildings and carried out abdominal, thoracic, head and neck, and limb surgery. Their role was to save life and to ensure that wounded soldiers were stable for casualty evacuation back down the line to a base hospital. There is a handful of memoirs by British doctors who worked in these units and they make enthralling reading. Casualty evacuation by air replaced the use of mobile surgical units in later wars, throwing into doubt their future relevance in the management of battle wounds. But recent re-evaluations by military planners suggest that their mobility still gives them a place, so the wartime memoirs may have more value than simply as war stories.


Assuntos
Medicina Militar , Militares , Humanos , II Guerra Mundial , Medicina Militar/história
16.
J Homosex ; 70(1): 135-148, 2023 Jan 02.
Artigo em Inglês | MEDLINE | ID: mdl-35904880

RESUMO

This essay analyzes how traditional notions of family are "queered" in contemporary memoir. I explore how heterosexual coupling becomes unnatural, undermining its equation with reproduction-and even the predictable forward march of family time becomes circular, haunted by alternate kinship models. I refer to this dynamic as "akin to kin" to consider how these representations both approximate and depart from normative ideas of family. I analyze several contemporary family memoirs to tease out moments in which "family" is imagined otherwise through queer relationalities.


Assuntos
Feminismo , Minorias Sexuais e de Gênero , Humanos , Identidade de Gênero , Heterossexualidade , Reprodução
18.
Polit Geogr ; 31(8): 495-508, 2012 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-23805031

RESUMO

This paper argues for the continued significance of the text as a source and focus in critical geopolitical inquiry. It establishes the utility of the military memoir in explorations of popular contemporary geopolitical imaginaries, and considers the memoir as a vector of militarism. The paper examines the memoirs written by military personnel about service in Afghanistan with the British armed forces, specifically about deployments to Helmand province between 2006 and 2012. The paper explores how Afghanistan is scripted through these texts, focussing on the explanations for deployment articulated by their authors, on the representations they contain and promote about other combatants and about civilian non-combatants, and the constitution and expression of danger in the spaces and places of military action which these texts construct and convey. The paper then turns to consider how a reading of the military memoir with reference to the genre of testimonio might extend and inform our understanding and use of these texts as a source for exploring popular geopolitics and militarism.

19.
Primates ; 63(3): 195-215, 2022 May.
Artigo em Inglês | MEDLINE | ID: mdl-35441992

RESUMO

This essay summarizes some of my findings while studying primates in the field from 1962 to 2018. Although I have studied primates throughout the tropics, I focused on Africa, primarily the Kibale Forest of Uganda. My research began in the early days of primate field studies when very little was known about the behavior and ecology of most species. Consequently, I was able to study nearly anything that could be observed under natural conditions. It was not necessary to specialize, and I opted to be a generalist. In much of my work I have attempted to understand the relationships between habitat quality, social organization, and population dynamics, emphasizing the great intraspecific variability that exists over time and between areas. Vocalizations have also long been of interest to me, starting with a description of predator-specific alarm calls and later showing how vocalizations among African monkeys appear to be evolutionarily stable. As my field experience progressed, I became increasingly involved with the conservation of tropical rain forests. In the last part of this essay I offer my thoughts on current trends in field primatology and some advice to the next generation of field biologists, stressing the importance of being a naturalist.


Assuntos
Ecologia , Ecossistema , Animais , Florestas , Primatas , Uganda
20.
Health (London) ; 26(5): 663-678, 2022 09.
Artigo em Inglês | MEDLINE | ID: mdl-34674571

RESUMO

The lifestyle model, which attributes etiological power and moral responsibility to the individual, is dominant in health promotion discourse. While sociologists rightly critique this model's individualistic outlook, there has been insufficient distinction between the two anti-individualistic models that commonly inform their work: the well-known "sociological model" and the culturally influential but under-conceptualized model tentatively called the "finitude model." Not only is there insufficient awareness of the different etiological causes (inequality and human fragility) and political orientations (redistribution and recognition) underlying the sociological and finitude models, but there is also insufficient recognition of how the finitude model may inform illness explanation. To raise awareness about the existence and analytical utility of the finitude model, I elucidate its core assumptions through a brief review of some influential texts in late-modern health politics. Further, I illustrate the empirical utility of the notion of the finitude model by analyzing how it is used to explain illness in Arthur Frank's and Kathlyn Conway's influential cancer memoirs. Thematic analysis of the memoirs produces two major findings. First, Frank and Conway rely on the finitude model to claim victimhood and blame the blamers. Second, they seem unaware of the double-edged character of such a model, which tends to downplay how social inequality shapes health. My analysis reveals the one-sidedness of both the finitude and sociological models, and that any illness explanation therefore needs to integrate both anti-individualistic models to challenge the lifestyle model successfully.


Assuntos
Estilo de Vida , Neoplasias , Humanos
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