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1.
Memory ; : 1-14, 2024 Sep 17.
Artigo em Inglês | MEDLINE | ID: mdl-39288236

RESUMO

Most people experience positive involuntary mental imagery (IMI) frequently in daily life; however, evidence for the importance and effects of positive IMI is largely indirect. The current study adapted a paradigm to experimentally induce positive IMI in participants' daily lives. This could in turn provide a means to directly test positive IMI's effects. In a within-subjects design, participants (N = 41) generated positive mental images (imagery condition) and sentences (verbal condition) from photo cues, half of which participants provided from their own living environment. Participants then recorded involuntary memories of the previously generated images or sentences in a seven-day diary, before returning to the lab and completing some measures including an involuntary memory task. In the diary, participants reported more involuntary memories from the imagery condition than from the verbal condition, and more involuntary memories from their own photos compared to the other photos. A more mixed pattern of findings was found across other tasks in the lab. The study indicates that the paradigm can be used as a means to induce positive IMI and that using photos as the basis for generating positive imagery increases the amount of IMI in daily life. Theoretical and potential clinical implications are discussed.

2.
Cogn Emot ; 38(1): 1-22, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-37943253

RESUMO

Positive emotions (PEs) impact cognitive processes, including executive functions (EFs; i.e. inhibition, working memory, cognitive flexibility). However, previous reviews and meta-analyses report contradicting results. Thus, this review takes a novel approach to overcome conflicting findings by clearly conceptualising PE induction and by providing a detailed description of the tasks used to assess EFs, as well as by exclusively focusing on EFs. A systematic literature review and meta-analysis was performed. Study inclusion criteria required that subjects were healthy individuals over 18 years, PEs were induced in a controlled laboratory setting, a baseline measurement and a control condition was required, and finally, EFs were measured as a dependent variable using valid measurement instruments. The literature search was performed on PRIMUS, including relevant databases such as ERIC, MEDLINE, Psych ARTICLES, Psych INFO or SocINDEX. From a total of 6,661 identified articles, only 13, which featured 20 experimental studies, were included. Results show that the overall induction of PEs successfully caused an increase in valence and/or positive emotions. However, no significant effects of PE on EFs were detected (d = -0.051, p = .405). Reasons and future research will be discussed.


Assuntos
Função Executiva , Memória de Curto Prazo , Humanos , Inibição Psicológica , Emoções
3.
Cogn Behav Ther ; 53(5): 544-560, 2024 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-38593029

RESUMO

This pilot study tested a single-session digital values affirmation for behavioral activation (VABA) intervention. Hypotheses predicted the VABA intervention would be more effective than an active control condition in improving mood, decreasing COVID-19 fear/worry and depressive symptoms, and promoting positively reinforcing behaviors during early weeks of the COVID-19 pandemic. Participants were a diverse sample of undergraduate students (N = 296) under a state-wide lockdown. Students were randomized to either VABA, a 10-min values clarification and affirmation task, or Control, a time- and attention-matched task. Positive and negative affects were assessed pre- and post-intervention. At next-day follow-up, positive and negative affects were reassessed, as well as past 24-h behavioral activation and depressive symptoms. Within-group increases in positive affect were observed in both conditions (VABA d = 0.39; Control d = 0.19). However, VABA produced a significantly larger increase than Control (F[2] = 3.856, p = .022, d = 0.22). At 24-h follow-up, behavioral activation, which was significantly higher in VABA versus Control (t[294] = -5.584, p < .001, d = 0.65), predicted fewer depressive symptoms (R2 change = .019, ß = -.134, p = .003). VABA is an ultra-brief intervention that appears to have acute effects on mood-enhancement and behavioral activation.


Assuntos
COVID-19 , Depressão , Humanos , COVID-19/psicologia , Masculino , Feminino , Projetos Piloto , Adulto Jovem , Depressão/psicologia , Depressão/terapia , Adulto , Afeto , Adolescente , Medo/psicologia , Ansiedade/psicologia , Ansiedade/terapia , Terapia Cognitivo-Comportamental/métodos , Estudantes/psicologia
4.
Curr Psychol ; : 1-13, 2023 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-37359669

RESUMO

This study explores the relationship between initial daily negative mood, online game usage and subsequent positive mood; and examine the moderating roles of hedonistic motivation on the perspective of mood regulation theory. To gather data over five consecutive workdays, this study used the experience sampling method. We then obtained 800 valid daily data from 160 participants. The results of multilevel path analysis show that: (i) initial daily negative mood increases the usage of online games and further enhances subsequent positive mood; (ii) students with higher hedonic motivation will show a stronger positive correlation between initial daily negative mood and online game usage; (iii) students with higher hedonic motivation will show a stronger positive correlation between online game usage and subsequent positive mood. Theoretical and practical implications are also investigated in this study.

5.
Alcohol Clin Exp Res ; 46(8): 1580-1591, 2022 08.
Artigo em Inglês | MEDLINE | ID: mdl-36029302

RESUMO

BACKGROUND: Attentional bias (AB) has been linked to alcohol use, mood, and alcohol craving, with key differences across different types of mood and biological sex. However, further exploration of the role of AB across these alcohol variables is needed. The current study examined the relationship between mood and AB as predictors of alcohol craving using ecological momentary assessment (EMA). Exploratory analysis examined these effects as a function of biological sex. METHODS: Participants (n = 69) from a Midwestern University carried a mobile device for 15 days and provided ratings of momentary mood (positive mood, anxious mood, and sad mood), alcohol craving, and AB. Data were analyzed using a two-level multilevel regression model, with associations between craving, mood, and AB examined at both the momentary and between-subjects levels. RESULTS: Across assessments, positive and negative moods were positively associated with momentary craving, with AB found to operate differently between men and women. At the within-subjects level, increases in positive mood among men strengthened the AB-craving association, while women showed stronger AB-craving associations when positive mood decreased. At the between-subjects level, trait-like sadness led to positive AB-craving associations for men, however, this was the opposite for women. Similarly, AB-craving associations were positive and robust for men with trait-like positive mood but again the opposite was observed for women. CONCLUSIONS: The findings highlight the importance and nuances of biological sex in the context of mood, AB, and craving. Interventions targeting AB and/or emotion regulation may yield different outcomes for men and women.


Assuntos
Viés de Atenção , Fissura , Afeto/fisiologia , Consumo de Bebidas Alcoólicas/psicologia , Fissura/fisiologia , Avaliação Momentânea Ecológica , Etanol , Feminino , Humanos , Masculino , Comportamento Sexual
6.
Eat Weight Disord ; 27(8): 3317-3330, 2022 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-35972642

RESUMO

PURPOSE: Earlier work on engaging in physical exercise when experiencing negative affect demonstrated robust associations with eating disorder (ED) behaviors and attitudes; however, measurement of the behavior was primitive, relying on one yes/no question that cannot capture much variability. We report on the development of a self-report measure, the Reactive Exercise Scale (RES), that disentangles the tendency to engage in exercise in response to negative mood cues from the tendency to engage in exercise in response to eating and body image cues, which themselves may be associated with negative mood. The measure also assesses exercising in response to positive mood cues. METHODS: Exploratory factor analysis (EFA) guided item and factor selection. Confirmatory factor analysis (CFA) in an independent sample tested a 3-factor solution-exercising in response to negative mood cues, eating and body image cues, and positive mood cues. Correlations with exercise attitudes, eating disorder and body image attitudes, mood, and personality were used to evaluate construct validity. RESULTS: Results supported the 3-factor structure and indicated that exercising in response to negative mood cues may not uniquely relate to most aspects of ED psychopathology when accounting for eating and body image cues, which themselves are associated with negative mood. CONCLUSION: The RES captures the tendency to exercise in response to negative mood, positive mood, and eating and body image cues. Together, these constructs allow researchers to examine the unique relations of negative mood cued exercise with ED constructs, while accounting for appearance-related motives for which exercise may also be used. LEVEL OF EVIDENCE: Level III: evidence obtained from well-designed cohort or case-control analytic studies.


Assuntos
Sinais (Psicologia) , Transtornos da Alimentação e da Ingestão de Alimentos , Humanos , Imagem Corporal , Afeto , Comportamento Alimentar , Exercício Físico
7.
Cogn Emot ; 35(6): 1136-1149, 2021 09.
Artigo em Inglês | MEDLINE | ID: mdl-34006189

RESUMO

This research investigated the effect of mood on self-reported effort in trying to focus back from mind wandering to ongoing things. We conducted three studies (one correlational and two experimental studies). Study 1 served as a correlational demonstration (questionnaires) of the negative relations between focus back effort and negative mood and between mind wandering and focus back effort at the trait level. Furthermore, a self-reported measure of focus back effort was developed to examine the effect of mood inductions on the ratings of focus back effort in the laboratory (Study 2) and daily life (Study 3). The findings of Studies 2 and 3 revealed that both in the laboratory and in daily life, participants in a negative mood reported lower levels of focus back effort rating than those in a positive mood. Thus, moods modulated mind wandering and an individual's effort in trying to focus back to some extent. Future work should account for the role of moods in mind wandering or focus back episodes.


Assuntos
Afeto , Laboratórios , Humanos , Estudos Longitudinais , Inquéritos e Questionários
8.
Cogn Process ; 22(2): 333-338, 2021 May.
Artigo em Inglês | MEDLINE | ID: mdl-33404901

RESUMO

In the present study, we investigated how positive mood affects the formation of time-based event expectancies. After positive or neutral mood inductions, participants performed a binary choice response task in which two target stimuli (circle and square) and two pre-target intervals (800 and 1600 ms) appeared equally often. One of the targets was paired with the short interval and the other target with the long interval in 90% of the trials. We found that participants from the positive and neutral groups showed markedly different behavioral patterns of time-based expectancy. The time-based expectancy was restricted to shorter intervals for the positive group and to longer intervals for the neutral group. We propose that positive mood increases attentional prioritization of information that is temporally closer to us.


Assuntos
Afeto , Atenção , Humanos
9.
Encephale ; 47(6): 533-539, 2021 Dec.
Artigo em Francês | MEDLINE | ID: mdl-33648753

RESUMO

INTRODUCTION: The Receptive Composite Montage (RCM) is a musical induction technique designed to cause a positive state to in-patients diagnosed with depression in a psychiatric institution. This research aims at proving that the RCM brings patients into a relaxation state and a positive mood within 20min. METHOD: Thirty-seven in-patients with depression took part in this study. The average age of the sample was slightly under 49 years old (48.73±12.41). The relaxing aspect of the RCM was monitored thanks to data given by an oximeter, which measures the heartbeats and the oxygen saturation level in the in-patient's bloodstream. In order to complete these data, a focal-sampling observation was carried out. Positive mood induction was estimated based on interviews. The data have been processed through analytical statistics. RESULTS: Heartbeats and oxygen saturation in the bloodstream during the relaxing phase of the montage (P<.001 and z=.018 respectively) tended to increase during the wake-up phase (P<.001) as was anticipated. In-patients who had felt a negative mood before listening to the RCM reported feeling a significant positive mood once they had listened to the RCM (z=.017). CONCLUSION: The results obtained show that the RCM does induce a relaxation state by decreasing heartbeats and breathing cycles. Moreover, the qualitative data show that when in-patients listen to the RCM, their mood becomes positive through an emotional exercise causing their mood to shift from negative to positive.


Assuntos
Musicoterapia , Afeto , Depressão , Hospitalização , Humanos , Pessoa de Meia-Idade , Saturação de Oxigênio
10.
Conscious Cogn ; 83: 102971, 2020 08.
Artigo em Inglês | MEDLINE | ID: mdl-32535498

RESUMO

Lucid dreaming is a unique phenomenon with potential applications for therapeutic interventions. Few studies have investigated the effects of lucidity on an individual's waking mood, which could have valuable implications for improving psychological wellbeing. The current experiment aims to investigate whether the experience of lucidity enhances positive waking mood, and whether lucidity is associated with dream emotional content and subjective sleep quality. 20 participants were asked to complete lucid dream induction techniques along with an online dream diary for one week, which featured a 19-item lucidity questionnaire, and subjective ratings of sleep quality, dream emotional content, and waking mood. Results indicated that higher lucidity was associated with more positive dream content and elevated positive waking mood the next day, although there was no relationship with sleep quality. The results of the research and suggestions for future investigations, such as the need for longitudinal studies of lucidity and mood, are discussed.


Assuntos
Afeto/fisiologia , Sonhos/fisiologia , Sono REM/fisiologia , Adulto , Feminino , Humanos , Masculino , Adulto Jovem
11.
J Pediatr Psychol ; 45(6): 622-632, 2020 07 01.
Artigo em Inglês | MEDLINE | ID: mdl-32403122

RESUMO

OBJECTIVE: This research examined whether the positive effects of a peer-communicated social norm that reduces risk-taking behaviors persist over time and if a reminder of this peer-communicated safety message has any impact on this outcome. METHODS: Positive mood in 7- to 9-year olds was induced experimentally and risk taking intentions and behaviors were measured when the child was in a positive and neutral mood state and after they had been exposed to either a safety or neutral peer-communicated social norm message. A few weeks later, half of the participants who experienced the safety social norm message were exposed to a reminder of this message via a slogan and risk-taking measures were taken again when in a heightened positive mood state. RESULTS: Exposure to a safety norm successfully counteracted the increase in risk taking associated with a positive mood state. These effects persisted for several weeks regardless of whether the children were exposed to a reminder. CONCLUSION: Manipulating peer social norms holds promise as an approach to produce reductions in children's risk taking and these effects persist at least over several weeks.


Assuntos
Grupo Associado , Assunção de Riscos , Normas Sociais , Criança , Humanos , Intenção , Comportamento Social
12.
Neuroimage ; 193: 115-125, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-30831312

RESUMO

Blunted activation in the reward circuitry has been associated with anhedonia, the inability to experience pleasure in previously rewarding activities. In healthy individuals, reward-related activation has been found to be modulated by acute contextual factors such as induced positive mood. Accordingly, blunted reward response in anhedonia might involve a failure to appropriately modulate reward-related activation as a function of context. To test this hypothesis, 29 participants (19 females, mean age of 24.14 ±â€¯4.61, age range 18-34), with a wide range of anhedonic symptoms, underwent functional MRI while anticipating and receiving monetary rewards, before and after a positive mood induction. Change in neural activation from before to after mood induction was quantified, and effects of anhedonia were investigated through whole-brain, ROI, and functional connectivity analyses. Contrary to hypotheses, results indicated that during reward anticipation (but not receipt), nucleus accumbens activation decreased while its connectivity with the dorsolateral prefrontal cortex increased, following positive mood induction. Critically, anhedonia modulated both effects. The unexpected finding of decreased activation to reward cues following positive mood induction is compelling as it aligns with a prominent behavioral model of the effect of positive mood on exploration of rewarding and neutral stimuli. Furthermore, the modulation of this effect by anhedonia suggests that it may be a key process altered in anhedonia.


Assuntos
Afeto/fisiologia , Anedonia/fisiologia , Encéfalo/fisiologia , Vias Neurais/fisiologia , Recompensa , Adolescente , Adulto , Feminino , Humanos , Masculino , Prazer/fisiologia , Adulto Jovem
13.
Brain Behav Immun ; 67: 314-323, 2018 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-28923405

RESUMO

Influenza vaccination is estimated to only be effective in 17-53% of older adults. Multiple patient behaviors and psychological factors have been shown to act as 'immune modulators' sufficient to influence vaccination outcomes. However, the relative importance of such factors is unknown as they have typically been examined in isolation. The objective of the present study was to explore the effects of multiple behavioral (physical activity, nutrition, sleep) and psychological influences (stress, positive mood, negative mood) on the effectiveness of the immune response to influenza vaccination in the elderly. A prospective, diary-based longitudinal observational cohort study was conducted. One hundred and thirty-eight community-dwelling older adults (65-85years) who received the 2014/15 influenza vaccination completed repeated psycho-behavioral measures over the two weeks prior, and four weeks following influenza vaccination. IgG responses to vaccination were measured via antigen microarray and seroprotection via hemagglutination inhibition assays at 4 and 16weeks post-vaccination. High pre-vaccination seroprotection levels were observed for H3N2 and B viral strains. Positive mood on the day of vaccination was a significant predictor of H1N1 seroprotection at 16weeks post-vaccination and IgG responses to vaccination at 4 and 16weeks post-vaccination, controlling for age and gender. Positive mood across the 6-week observation period was also significantly associated with post-vaccination H1N1 seroprotection and IgG responses to vaccination at 16weeks post-vaccination, but in regression models the proportion of variance explained was lower than for positive mood on the day of vaccination alone. No other factors were found to significantly predict antibody responses to vaccination. Greater positive mood in older adults, particularly on the day of vaccination, is associated with enhanced responses to vaccination.


Assuntos
Afeto , Vacinas contra Influenza/uso terapêutico , Influenza Humana/prevenção & controle , Vacinação/psicologia , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Imunoglobulina G/sangue , Estudos Longitudinais , Masculino , Estudos Prospectivos , Resultado do Tratamento
14.
J Pediatr Psychol ; 42(7): 748-758, 2017 08 01.
Artigo em Inglês | MEDLINE | ID: mdl-28369618

RESUMO

Objective: This study examined whether exposure to a safety norm could counteract the increase in risk taking children show when in an elevated positive mood state. Methods: Risk taking (intentions, behaviors) was measured in a neutral and positive (induced experimentally) mood state. Before completing the tasks in a positive mood, 120 children 7-10 years were exposed to either a safety norm or a control audio. Results: The control audio had no effect: children showed an increase in risk taking and intentions when in a positive mood compared with a neutral mood, replicating past research. In contrast, exposure to the safety norm counteracted this effect: children showed a decrease in risk taking and intentions when in a positive mood compared with a neutral mood. Conclusion: Manipulating children's exposure to social norms can be an effective strategy for reducing injury-risk behaviors even when they are in an elevated positive mood state.


Assuntos
Afeto , Comportamento Infantil/psicologia , Grupo Associado , Assunção de Riscos , Segurança , Normas Sociais , Ferimentos e Lesões/prevenção & controle , Criança , Feminino , Humanos , Intenção , Masculino , Ferimentos e Lesões/psicologia
15.
Ann Behav Med ; 50(1): 12-23, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26272466

RESUMO

BACKGROUND: Although a relationship between mood and pain has been established cross-sectionally, little research has examined this relationship using momentary within-person data. PURPOSE: We examined whether baseline depressive symptoms and within-person levels of negative and positive mood predicted momentary pain among 31 individuals with rheumatoid arthritis (RA). METHODS: Depressive symptomatology was measured at baseline. Mood and RA symptoms were self-reported via ecological momentary assessment five times a day for seven consecutive days. Analyses controlled for gender, age, weekend day, time of day, and experiences of stress. RESULTS: Greater momentary positive mood was associated with less momentary pain and fewer arthritis-related restrictions; negative mood was associated with more restrictions. Greater depressive symptomatology also predicted more pain and restrictions, an effect which was not accounted for by mood. CONCLUSIONS: Results suggest that both depression and mood are uniquely associated with momentary pain; as such, multi-component interventions may provide optimal disease management.


Assuntos
Afeto , Artrite Reumatoide/complicações , Artrite Reumatoide/psicologia , Depressão/complicações , Depressão/psicologia , Dor/complicações , Dor/psicologia , Depressão/diagnóstico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Autorrelato , Avaliação de Sintomas
16.
J Pediatr Psychol ; 40(4): 406-18, 2015 May.
Artigo em Inglês | MEDLINE | ID: mdl-25466880

RESUMO

OBJECTIVE: To examine whether children engage in greater risk taking when in a positive versus neutral mood state, and whether positive urgency trait relates to risk taking. METHODS: Positive mood in 7-10-year-old children was induced experimentally, and children's risk-taking intentions and actual behaviors were measured when the child was in a positive and neutral mood state. RESULTS: Within-person comparisons revealed that children showed greater risk-taking intentions and actual risk behaviors when in a positive mood state compared with a neutral one. Positive urgency was associated with greater risk taking when in a positive mood state, and this effect was stronger in the actual risk taking than intentions to risk take task. CONCLUSIONS: Mood state affects children's risk taking. Positive mood is associated with greater risk taking in elementary-school children, and those high in positive urgency are especially likely to show this effect. Implications for injury prevention are discussed.


Assuntos
Afeto , Comportamento Infantil/psicologia , Assunção de Riscos , Criança , Feminino , Humanos , Intenção , Masculino
17.
Am J Geriatr Psychiatry ; 22(12): 1592-602, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-24566240

RESUMO

OBJECTIVE: This study examines effects of daily use of adult day service (ADS) programs by caregivers of individuals with dementia (IWD) on a salivary biomarker of stress reactivity, dehydroepiandrosterone-sulfate (DHEA-S), and whether these effects on DHEA-S are associated with daily variability in positive mood and depressive symptoms. METHODS: We used a daily diary design of 8 consecutive days with alternation of intervention (ADS) and nonintervention days to evaluate within- and between-person effects of the intervention. Family caregivers (N = 151) of IWD who were using ADS were interviewed daily by telephone at home. Saliva samples were collected from caregivers five times a day for 8 consecutive days and were assayed for DHEA-S. Daily telephone interviews assessed daily stressors and mood. RESULTS: DHEA-S levels were significantly higher on days after ADS use. Daily DHEA-S levels covaried significantly with daily positive mood but not with depressive symptoms. CONCLUSION: These results demonstrate an association of ADS use by family caregivers and higher DHEA-S levels on the next day. Prior research has found that higher DHEA-S levels are protective against the physiologic damaging effects of stressor exposure and may reduce risks of illness. Regular use of ADS may help reduce depletion of DHEA-S and allow the body to mount a protective and restorative response to the physiologic demands of caregiving. To our knowledge, this is the first study to examine DHEA-S levels across the day in connection with an intervention that affected daily exposure to stressors.


Assuntos
Afeto/fisiologia , Cuidadores/psicologia , Hospital Dia/psicologia , Sulfato de Desidroepiandrosterona/metabolismo , Demência/enfermagem , Depressão/metabolismo , Estresse Psicológico/metabolismo , Adulto , Idoso , Idoso de 80 Anos ou mais , Biomarcadores/metabolismo , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
18.
EBioMedicine ; 99: 104902, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38141395

RESUMO

BACKGROUND: Intravenous (IV) ketamine has emerged as a rapid and effective treatment for TRD. However, the specific neural mechanisms of ketamine's effects in humans remains unclear. Although neuroplasticity is implicated as a mechanism of action in animal models, relatively few randomized controlled trials (RCTs) in TRD patients have examined ketamine's impact on functional connectivity, a posited functional marker of neuroplasticity-particularly in the context of a mood-induction paradigm (termed miFC). METHODS: 152 adults with TRD (63% female; 37% male) were randomly allocated to receive a single infusion of ketamine or saline in a 2:1 ratio. We examined changes in connectivity (from baseline to 24-h post-infusion) that differed by treatment, and whether clinical treatment response at 24-h post-infusion was uniquely related (among patients allocated to ketamine relative to saline) to (1) pre-treatment connectivity and (2) changes in connectivity. We examined both miFC and rsFC, using prefrontal cortex and limbic seed regions. We also conducted a multiverse analysis to examine findings most robust against analytic decisions. FINDINGS: Across both miFC and rsFC, ketamine was associated with greater in prefrontal/limbic connectivity compared to saline, and lower baseline connectivity of limbic and prefrontal regions predicted greater treatment response in patients receiving ketamine. Greater connectivity increases in participants receiving ketamine was uniquely related to greater treatment response. In addition, certain findings were identified as being reproducible against different analytic decisions in multiverse analyses. INTERPRETATION: Our findings identify specific neural connectivity patterns impacted by ketamine and were uniquely related to outcomes following ketamine (relative to saline). These findings generally support prominent neuroplasticity models of ketamine's therapeutic efficacy. These findings lay new groundwork for understanding how to enhance and optimize ketamine treatments and develop novel rapid-acting treatments for depression. FUNDING: This research was supported by NIH grant R01MH113857 and by the Clinical and Translational Sciences Institute at the University of Pittsburgh (UL1-TR-001857).


Assuntos
Ketamina , Adulto , Masculino , Feminino , Animais , Humanos , Ketamina/farmacologia , Ketamina/uso terapêutico , Antidepressivos/farmacologia , Antidepressivos/uso terapêutico , Depressão/tratamento farmacológico , Córtex Pré-Frontal/diagnóstico por imagem , Resultado do Tratamento , Ensaios Clínicos Controlados Aleatórios como Assunto
19.
Behav Res Ther ; 174: 104490, 2024 03.
Artigo em Inglês | MEDLINE | ID: mdl-38354451

RESUMO

Previous laboratory work has shown that induction of positive mood prior to fear extinction decreases the negative valence of the conditional stimulus (CS) and reduces reinstatement of fear. Before translating these insights to clinical practice, it is important to test this strategy in anxious individuals. Students with a high fear of public speaking (N = 62) were randomized to either a positive mood induction, a negative mood induction, or no induction control group. All participants performed two weekly sessions of virtual reality exposure and a 1-week follow-up test including a spontaneous recovery test and reinstatement test after a social rejection (unconditional stimulus). We used self-reported fear measures and skin conductance responses. We expected that the positive group, compared to the other groups, would evaluate the CS (i.e., speaking in front of an audience) as less negative following exposure and would show less spontaneous recovery and reinstatement of fear following a social rejection. Although mood was successfully manipulated, there were no group differences in CS valence following exposure. In all conditions, VR exposure successfully reduced public speaking fear, and these effects were stable at follow-up. In contrast with expectations, the positive group showed more spontaneous recovery of CS negative valence than the negative group. To conclude, we found no evidence that positive mood induction prior to exposure optimizes exposure effects for anxious individuals.


Assuntos
Extinção Psicológica , Medo , Humanos , Medo/fisiologia , Extinção Psicológica/fisiologia , Fala , Condicionamento Clássico/fisiologia , Ansiedade/terapia
20.
JMIR Ment Health ; 11: e52790, 2024 Mar 13.
Artigo em Inglês | MEDLINE | ID: mdl-38477970

RESUMO

BACKGROUND: Therapist-guided exposure and response prevention (ERP) for the treatment of obsessive-compulsive disorder (OCD) is frequently conducted within clinical settings but rarely at places where patients are usually confronted with OCD symptom-provoking situations in daily life (eg, at home). OBJECTIVE: This study aimed to investigate patients' views on 1 ERP session at home via videoconference and its impact on treatment outcome. METHODS: A total of 64 inpatients with OCD received 1 session of therapist-guided videoconference-based ERP at home in adjunction to a multimodal inpatient treatment between 2015 and 2020. RESULTS: Compared with 64 age- and sex-matched controls who received a multimodal inpatient treatment without 1 session of videoconference-based ERP at home, patients who received 1 session of videoconference-based ERP in adjunction to a multimodal inpatient treatment showed stronger reductions in OCD symptom severity from admission to discharge. Before the videoconference-based ERP session, patients reported high rationale credibility and treatment expectancy. After the videoconference-based ERP session, patients reported medium-to-high positive mood as well as depth and smoothness of the session, and they perceived the working alliance as high. CONCLUSIONS: Results highlight the importance of administering therapist-guided ERP sessions in patients' natural environment to enhance treatment response in OCD. Videoconference-based ERP as add-on to treatment as usual is, therefore, a promising approach to facilitate the application of ERP in patients' natural environment and foster the generalization of ERP conducted in clinical settings.


Assuntos
Assistência Odontológica , Pacientes Internados , Humanos , Hospitalização , Alta do Paciente , Comunicação por Videoconferência
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