Malignant Warthin's tumour: a case study.

Malignant transformation of a benign Warthin's tumour (adenolymphoma) is extremely rare. The light microscopic and ultrastructural features of an adenocarcinoma arising in a Warthin's tumour in the parotid gland are described. Light microscopy demonstrated a transition zone from the benign to the malignant component, and the malignant cells revealed oncocytic features by both light- and electronmicroscopy.

[Primary and secondary neoplasms of the salivary glands in the province of Trieste (1977-1986). Histopathological review and epidemiological picture of 151 cases]. / Neoplasie primitive e secondarie delle ghiandole salivari nella provincia di Trieste (1977-1986). Revisione istopatologica ed inquadramento epidemiologico di 151 casi.

The authors carried out a histopathological and epidemiological study on 151 cases of primary and secondary neoplasms of the salivary glands. The parotid gland was involved in 117 cases (78.5%). The tumours were malignant in 20% (30 cases) of the lesions. The most common neoplasms were pleomorphic adenoma (74 cases) and adenolymphoma (35 cases). The occurrence of the latter were, for both sexes, directly correlated to the age of the subjects. The malignant neoplasms were also in direct relation to age. In 7 patients pleomorphic adenoma recurred (11.3%) and in 3 of these the tumour showed a carcinomatous change. The world standardized incidence of malignant forms in the province of Trieste was slightly lower than that for other countries with a similar socio-economic and demographic situation.