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1.
Emerg Infect Dis ; 30(1): 192-194, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38147514

RESUMO

Fewer than 30 cases of Mycobacterium senegalense infection have been reported. We report a complicated case of M. senegalense infection in Memphis, Tennessee, in the southeastern United States. The patient's comorbidities of past organ transplant and insulin-dependent diabetes required delicate consideration of those health conditions to guide treatment.


Assuntos
Diabetes Mellitus , Transplante de Rim , Infecções por Mycobacterium não Tuberculosas , Infecções por Mycobacterium , Mycobacterium , Humanos , Mycobacterium/genética , Tennessee/epidemiologia , Transplante de Rim/efeitos adversos , Infecções por Mycobacterium/diagnóstico , Infecções por Mycobacterium/tratamento farmacológico , Infecções por Mycobacterium/etiologia , Infecções por Mycobacterium não Tuberculosas/diagnóstico , Infecções por Mycobacterium não Tuberculosas/tratamento farmacológico , Infecções por Mycobacterium não Tuberculosas/microbiologia
2.
Emerg Infect Dis ; 30(6): 1245-1248, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38782142

RESUMO

Choanephora infundibulifera is a member of the Mucorales order of fungi. The species is associated with plants as a saprophyte or parasite and may be responsible for spoilage or disease but is an uncommon cause of human infection. We describe C. infundibulifera rhinosinusitis in a young man with leukemia in Tennessee, USA.


Assuntos
Sinusite , Humanos , Masculino , Tennessee , Sinusite/microbiologia , Sinusite/diagnóstico , Sinusite/parasitologia , Leucemia-Linfoma Linfoblástico de Células Precursoras/complicações , Mucormicose/diagnóstico , Mucormicose/microbiologia , Mucormicose/tratamento farmacológico , Mucorales/isolamento & purificação , Mucorales/classificação , Rinite/microbiologia , Rinite/diagnóstico , Adulto , Antifúngicos/uso terapêutico , Rinossinusite
3.
MMWR Morb Mortal Wkly Rep ; 73(12): 260-264, 2024 Mar 28.
Artigo em Inglês | MEDLINE | ID: mdl-38547036

RESUMO

Syndromic polymerase chain reaction (PCR) panels are used to test for pathogens that can cause rash illnesses, including measles. Rash illnesses have infectious and noninfectious causes, and approximately 5% of persons experience a rash 7-10 days after receipt of a measles, mumps, and rubella (MMR) vaccine. MMR vaccine includes live attenuated measles virus, which is detectable by PCR tests. No evidence exists of person-to-person transmission of measles vaccine virus, and illness does not typically result among immunocompetent persons. During September 2022-January 2023, the Tennessee Department of Health received two reports of measles detected by syndromic PCR panels. Both reports involved children (aged 1 and 6 years) without known risk factors for measles, who were evaluated for rash that occurred 11-13 days after routine MMR vaccination. After public health responses in Tennessee determined that both PCR panels had detected measles vaccine virus, six state health departments collaborated to assess the frequency and characteristics of persons receiving a positive measles PCR panel test result in the United States. Information was retrospectively collected from a commercial laboratory testing for measles in syndromic multiplex PCR panels. During May 2022-April 2023, among 1,548 syndromic PCR panels, 17 (1.1%) returned positive test results for measles virus. Among 14 persons who received a positive test result and for whom vaccination and case investigation information were available, all had received MMR vaccine a median of 12 days before specimen collection, and none had known risk factors for acquiring measles. All positive PCR results were attributed to detection of measles vaccine virus. Increased awareness among health care providers about potential measles detection by PCR after vaccination is needed. Any detection of measles virus by syndromic PCR testing should be immediately reported to public health agencies, which can use measles vaccination history and assessment of risk factors to determine the appropriate public health response. If a person recently received MMR vaccine and has no risk factors for acquiring measles, additional public health response is likely unnecessary.


Assuntos
Exantema , Sarampo , Caxumba , Rubéola (Sarampo Alemão) , Criança , Humanos , Estados Unidos/epidemiologia , Lactente , Vacina contra Sarampo-Caxumba-Rubéola , Estudos Retrospectivos , Sarampo/diagnóstico , Sarampo/epidemiologia , Sarampo/prevenção & controle , Vírus do Sarampo/genética , Caxumba/prevenção & controle , Vacinação , Tennessee/epidemiologia , Reação em Cadeia da Polimerase , Rubéola (Sarampo Alemão)/prevenção & controle , Anticorpos Antivirais
4.
Ann Allergy Asthma Immunol ; 132(4): 485-490.e2, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38081410

RESUMO

BACKGROUND: Children in metro Shelby County, Tennessee, have disproportionally high asthma-related health care resource use (HRU) compared with those in other regions in Tennessee. OBJECTIVE: To describe the goals, logistics, and outcomes of the Changing High-Risk Asthma in Memphis through Partnership (CHAMP) program implemented to improve pediatric asthma care in Shelby County. METHODS: CHAMP established a multidisciplinary team with dedicated medical staff and community health workers, implemented a 24/7 call line to improve access to care, established a patient data registry to address fragmented care, assigned community health educators to improve asthma education and social needs, and partnered with services to address environmental triggers and social determinants of health. Patients eligible for CHAMP are Shelby County residents aged 2 to 18 years with high-risk asthma enrolled in Tennessee's Medicaid managed care program. Health care resource use outcomes 1-year pre- and post-CHAMP enrollment were analyzed for patients who had completed 1 year of CHAMP between January 2013 and December 2022. The 24/7 call line data between November 2013 and December 2022 were analyzed. RESULTS: CHAMP has enrolled 1348 children; 945 have completed 1 year (63% male; 90% identified as Black). At 1-year post-CHAMP enrollment, patients had 58%, 68%, 42%, and 53% reductions in emergency department visits, inpatient and observation visits, urgent care visits, and total asthma exacerbations, respectively. The number of asthma exacerbations per patient significantly decreased from 2.97 to 1.40 at 1-year post-CHAMP enrollment. Of the calls made to the 24/7 call line, 58% occurred after hours and 52% led to issue resolution without a medical facility visit. CONCLUSION: CHAMP successfully decreased asthma HRU in children with high-risk asthma in Shelby County by implementing initiatives that targeted barriers to asthma care.


Assuntos
Asma , Medicaid , Estados Unidos , Criança , Humanos , Masculino , Feminino , Asma/epidemiologia , Asma/terapia , Tennessee/epidemiologia , Programas de Assistência Gerenciada , Ohio
5.
BMC Infect Dis ; 24(1): 717, 2024 Jul 22.
Artigo em Inglês | MEDLINE | ID: mdl-39039476

RESUMO

BACKGROUND: The use of telemedicine has grown significantly since the COVID-19 pandemic and has the potential to improve access to specialized care for otherwise underserved populations. Incarcerated people living with HIV (PLWH) could potentially benefit from expanded access to HIV care through telemedicine. METHODS: All PLWH who were incarcerated within the Tennessee Department of Corrections and received care through the HIV telemedicine clinic at Regional One Hospital between 5/1/2019 through 2/28/2022 were identified from the electronic health records (EHR). Demographics, laboratory data, vaccine history, and treatment outcomes were abstracted from the EHR. Retention in care and viral suppression were defined using Centers for Disease Control and Prevention definitions. RESULTS: Of the 283 incarcerated PLWH receiving care from this telemedicine clinic, 78% remained retained in care and 94% achieved or maintaining viral suppression at 12 months. Many preventative care measures remained unperformed or undocumented, including vaccinations and testing for concurrent sexually transmitted infections. There were 56 patients (20%) found to have chronic hepatitis C in this population, with 71% either cured or still on treatment in this study period. CONCLUSIONS: Retention in care and viral suppression rates were excellent among incarcerated PLWH receiving telemedicine care for their HIV. HIV related primary health care screenings and vaccinations, however, were less consistently documented and represent areas for improvement.


Assuntos
COVID-19 , Infecções por HIV , Prisioneiros , Telemedicina , Humanos , Infecções por HIV/terapia , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , COVID-19/terapia , COVID-19/epidemiologia , Estudos de Coortes , Atenção à Saúde , SARS-CoV-2 , Tennessee
6.
J Urban Health ; 101(2): 349-363, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38485845

RESUMO

Inequities in urban greenspace have been identified, though patterns by race and socioeconomic status vary across US settings. We estimated the magnitude of the relationship between a broad mixture of neighborhood-level factors and residential greenspace using weighted quantile sum (WQS) regression, and compared predictive models of greenspace using only neighborhood-level, only individual-level, or multi-level predictors. Greenspace measures included the Normalized Difference Vegetation Index (NDVI), tree canopy, and proximity of the nearest park, for residential locations in Shelby County, Tennessee of children in the CANDLE cohort. Neighborhood measures include socioeconomic and education resources, as well as racial composition and racial residential segregation. In this sample of 1012 mother-child dyads, neighborhood factors were associated with higher NDVI and tree canopy (0.021 unit higher NDVI [95% CI: 0.014, 0.028] per quintile increase in WQS index); homeownership rate, proximity of and enrollment at early childhood education centers, and racial composition, were highly weighted in the WQS index. In models constrained in the opposite direction (0.028 unit lower NDVI [95% CI: - 0.036, - 0.020]), high school graduation rate and teacher experience were highly weighted. In prediction models, adding individual-level predictors to the suite of neighborhood characteristics did not meaningfully improve prediction accuracy for greenspace measures. Our findings highlight disparities in greenspace for families by neighborhood socioeconomic and early education factors, and by race, suggesting several neighborhood indicators for consideration both as potential confounders in studies of greenspace and pediatric health as well as in the development of policies and programs to improve equity in greenspace access.


Assuntos
Parques Recreativos , Características de Residência , Humanos , Tennessee , Feminino , Masculino , Criança , Características de Residência/estatística & dados numéricos , Parques Recreativos/estatística & dados numéricos , Características da Vizinhança , Fatores Socioeconômicos , Pré-Escolar , Adulto , Planejamento Ambiental
7.
Environ Health ; 23(1): 17, 2024 Feb 08.
Artigo em Inglês | MEDLINE | ID: mdl-38331928

RESUMO

BACKGROUND: Green space exposures may promote child mental health and well-being across multiple domains and stages of development. The aim of this study was to investigate associations between residential green space exposures and child mental and behavioral health at age 4-6 years. METHODS: Children's internalizing and externalizing behaviors in the Conditions Affecting Neurocognitive Development and Learning in Early Childhood (CANDLE) cohort in Shelby County, Tennessee, were parent-reported on the Child Behavior Checklist (CBCL). We examined three exposures-residential surrounding greenness calculated as the Normalized Difference Vegetation Index (NDVI), tree cover, and park proximity-averaged across the residential history for the year prior to outcome assessment. Linear regression models were adjusted for individual, household, and neighborhood-level confounders across multiple domains. Effect modification by neighborhood socioeconomic conditions was explored using multiplicative interaction terms. RESULTS: Children were on average 4.2 years (range 3.8-6.0) at outcome assessment. Among CANDLE mothers, 65% self-identified as Black, 29% as White, and 6% as another or multiple races; 41% had at least a college degree. Higher residential surrounding greenness was associated with lower internalizing behavior scores (-0.66 per 0.1 unit higher NDVI; 95% CI: -1.26, -0.07) in fully-adjusted models. The association between tree cover and internalizing behavior was in the hypothesized direction but confidence intervals included the null (-0.29 per 10% higher tree cover; 95% CI: -0.62, 0.04). No associations were observed between park proximity and internalizing behavior. We did not find any associations with externalizing behaviors or the attention problems subscale. Estimates were larger in neighborhoods with lower socioeconomic opportunity, but interaction terms were not statistically significant. CONCLUSIONS: Our findings add to the accumulating evidence of the importance of residential green space for the prevention of internalizing problems among young children. This research suggests the prioritization of urban green spaces as a resource for child mental health.


Assuntos
Mães , Parques Recreativos , Criança , Feminino , Humanos , Pré-Escolar , Ohio , Tennessee/epidemiologia
8.
Health Expect ; 27(3): e14074, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38769887

RESUMO

OBJECTIVE: Explore barriers to healthcare access in Hancock County, Tennessee using a conceptual framework for access to healthcare. METHODS: We collected data from 30 participants in Hancock County during 1 week in April 2023 using a combination of network and purposive sampling. We analyzed the data using thematic analysis and the conceptual framework of healthcare access. RESULTS: All dimensions of the conceptual framework of healthcare access presented barriers to healthcare access for participants of the study. A lack of acceptability of local healthcare among participants manifested in a perceived lack of availability of healthcare. This resulted in participants travelling or considering it necessary to travel long distances for care, even in a life-threatening emergency, despite the local availability of a hospital with an emergency department. CONCLUSIONS: A lack of acceptability can create healthcare access barriers similar to a lack of availability of healthcare facilities. PATIENT OR PUBLIC CONTRIBUTION: The research team met several times with the leader of a local community organization to discuss this research in Hancock County. These conversations helped to inform the study design and provided necessary background to conduct in-depth interviews. Members of the community organization helped identify individuals to interview and provide access to Remote Area Medical clinic patients. The research team discussed the final themes with the primary community collaborator.


Assuntos
Acessibilidade aos Serviços de Saúde , Pesquisa Qualitativa , Humanos , Tennessee , Feminino , Masculino , Adulto , Pessoa de Meia-Idade , Idoso , Entrevistas como Assunto
9.
BMC Public Health ; 24(1): 83, 2024 01 03.
Artigo em Inglês | MEDLINE | ID: mdl-38172812

RESUMO

BACKGROUND: In an effort to reduce viral transmission, many schools reduced class sizes during the recent pandemic. Yet the effect of class size on transmission is unknown. METHODS: We used data from Project STAR, a randomized controlled trial in which 10,816 Tennessee elementary students were assigned at random to smaller classes (13 to 17 students) or larger classes (22 to 26 students) in 1985-89. We merged Project STAR schools with data on local deaths from pneumonia and influenza in the 122 Cities Mortality Report System. Using mixed effects linear, Poisson, and negative binomial regression, we estimated the main effect of smaller classes on absence. We used an interaction to test whether the effect of small classes on absence was larger when and where community pneumonia and influenza prevalence was high. RESULTS: Small classes reduced absence by 0.43 days/year (95% CI -0.06 to -0.80, p < 0.05), but small classes had no significant interaction with community pneumonia and influenza mortality (95% CI -0.27 to + 0.30, p > 0.90), indicating that the reduction in absence due to small classes was not larger when community disease prevalence was high. CONCLUSION: Small classes reduced absence, but the reduction was not larger when disease prevalence was high, so the reduction in absence was not necessarily achieved by reducing infection. Small classes, by themselves, may not suffice to reduce the spread of respiratory viruses.


Assuntos
Influenza Humana , Pneumonia , Criança , Humanos , Influenza Humana/epidemiologia , Influenza Humana/prevenção & controle , Instituições Acadêmicas , Estudantes , Tennessee/epidemiologia , Pneumonia/epidemiologia , Pneumonia/prevenção & controle
10.
BMC Health Serv Res ; 24(1): 640, 2024 May 18.
Artigo em Inglês | MEDLINE | ID: mdl-38760660

RESUMO

BACKGROUND: Despite efforts to enhance the quality of medication prescribing in outpatient settings, potentially inappropriate prescribing remains common, particularly in unscheduled settings where patients can present with infectious and pain-related complaints. Two of the most commonly prescribed medication classes in outpatient settings with frequent rates of potentially inappropriate prescribing include antibiotics and nonsteroidal anti-inflammatory drugs (NSAIDs). In the setting of persistent inappropriate prescribing, we sought to understand a diverse set of perspectives on the determinants of inappropriate prescribing of antibiotics and NSAIDs in the Veterans Health Administration. METHODS: We conducted a qualitative study guided by the Consolidated Framework for Implementation Research and Theory of Planned Behavior. Semi-structured interviews were conducted with clinicians, stakeholders, and Veterans from March 1, 2021 through December 31, 2021 within the Veteran Affairs Health System in unscheduled outpatient settings at the Tennessee Valley Healthcare System. Stakeholders included clinical operations leadership and methodological experts. Audio-recorded interviews were transcribed and de-identified. Data coding and analysis were conducted by experienced qualitative methodologists adhering to the Consolidated Criteria for Reporting Qualitative Studies guidelines. Analysis was conducted using an iterative inductive/deductive process. RESULTS: We conducted semi-structured interviews with 66 participants: clinicians (N = 25), stakeholders (N = 24), and Veterans (N = 17). We identified six themes contributing to potentially inappropriate prescribing of antibiotics and NSAIDs: 1) Perceived versus actual Veterans expectations about prescribing; 2) the influence of a time-pressured clinical environment on prescribing stewardship; 3) Limited clinician knowledge, awareness, and willingness to use evidence-based care; 4) Prescriber uncertainties about the Veteran condition at the time of the clinical encounter; 5) Limited communication; and 6) Technology barriers of the electronic health record and patient portal. CONCLUSIONS: The diverse perspectives on prescribing underscore the need for interventions that recognize the detrimental impact of high workload on prescribing stewardship and the need to design interventions with the end-user in mind. This study revealed actionable themes that could be addressed to improve guideline concordant prescribing to enhance the quality of prescribing and to reduce patient harm.


Assuntos
Antibacterianos , Anti-Inflamatórios não Esteroides , Prescrição Inadequada , Padrões de Prática Médica , Pesquisa Qualitativa , United States Department of Veterans Affairs , Humanos , Anti-Inflamatórios não Esteroides/uso terapêutico , Estados Unidos , Antibacterianos/uso terapêutico , Prescrição Inadequada/estatística & dados numéricos , Prescrição Inadequada/prevenção & controle , Padrões de Prática Médica/estatística & dados numéricos , Masculino , Feminino , Entrevistas como Assunto , Pessoa de Meia-Idade , Pacientes Ambulatoriais , Tennessee
11.
Int J Biometeorol ; 68(4): 637-646, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38189990

RESUMO

Nighttime heat is an important factor in heat-health outcomes, though nighttime heat exposure and its impacts are poorly understood. We assessed overnight heat in indoor (n = 12) and outdoor (n = 3) living spaces in Knoxville, Tennessee, using iButton Hygrochrons in August 2021. Indoor sleep spaces, all of which were air conditioned, reported a variety of overnight conditions. Indoor sleep spaces were both warmer and cooler than outdoor temperatures overnight, and some participants noted having physical health effects of overnight heat in their homes. Downtown outdoor sleep spaces, including a park and encampment, exhibited an urban heat island signal, staying warmer than other outdoor areas. Future research should focus on the intensity and length of the overnight recovery period for individuals and how that affects heat-health outcomes, especially after being exposed to daytime heat. Specifically, do homes reach a cool enough temperature for recovery, and do outdoor sleeping spaces offer a long enough and cool enough period for recovery? We provide some recommendations for such future studies, including (1) focus on purposeful sampling, (2) use deliberate sensor placement for representative results, (3) prepare for participant drop-off due to non-compliance and technological problems, and (4) strategically gather demographic information.


Assuntos
Temperatura Alta , Habitação , Humanos , Cidades , Tennessee , Temperatura
12.
South Med J ; 117(8): 474-477, 2024 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-39094796

RESUMO

OBJECTIVE: Financial burdens of medical education are a major barrier for many students. The goal of this study is to identify and quantify unforeseen costs associated with being a medical student. METHODS: Medical students at the University of Tennessee Health Science Center were surveyed on unforeseen financial costs. Qualitative data were collected. RESULTS: Students spent significant extra funds in professional development, social spending, living, and technology. CONCLUSION: Schools and students should consider all aspects of life to have a fruitful education and appropriately provide loan funding and financial education for both enough and thoughtful use of financial resources during medical education.


Assuntos
Educação Médica , Estudantes de Medicina , Humanos , Estudantes de Medicina/estatística & dados numéricos , Tennessee , Educação Médica/economia , Educação Médica/métodos , Masculino , Feminino , Inquéritos e Questionários , Adulto
13.
South Med J ; 117(6): 291-295, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38830581

RESUMO

OBJECTIVES: The purpose of this study was to examine the factors associated with vision impairment (VI), age-related eye disease (ARED), and frequency of eye examinations among older adults. METHODS: A cross-sectional study (N = 166) was designed to identify barriers in vision and eye care services among adults 50 years and older in four counties in Appalachian Tennessee. Surveys were administered in March 2023. Simple and multiple logistic regression analyses were used to determine the risk factors of VI and ARED and the frequency of eye examinations. RESULTS: In two out of the three regression models, predictors such as traveling >10 mi to an eye care provider, barriers to eye care, and a lack of exposure to eye health information emerged as significant factors. Individuals who traveled >10 mi to an eye care provider were more than twice as likely than individuals who traveled shorter distances to have VI and not maintain routine eye care (adjusted odds ratio [AOR] 2.69, 95% confidence interval [CI] 1.08-6.75; AOR 2.82, 95% CI 1.05-7.55, respectively). Reporting barriers to eye care doubled the odds of ARED (AOR 2.33, 95% CI 1.02-5.34) and substantially increased the odds of reporting a 3-year or longer interval since the last eye examination (AOR 7.45, 95% CI 1.85-29.96) compared with having no barriers to eye care. Moreover, limited exposure to eye health information tripled the odds of VI (AOR 3.26, 95% CI 1.15-9.24) and not maintaining routine eye care (AOR 3.07, 95% CI 0.97-9.70) compared with more exposure to eye health information. Other predictors also were uncovered in the analysis. CONCLUSIONS: This study contributes to the scarce literature on risk factors associated with vision health among older adults in Appalachia.


Assuntos
Transtornos da Visão , Humanos , Tennessee/epidemiologia , Masculino , Feminino , Idoso , Estudos Transversais , Pessoa de Meia-Idade , Transtornos da Visão/epidemiologia , Fatores de Risco , Acessibilidade aos Serviços de Saúde/estatística & dados numéricos , Idoso de 80 Anos ou mais , Oftalmopatias/epidemiologia , Inquéritos e Questionários
14.
Ann Plast Surg ; 92(1): 50-54, 2024 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-37856233

RESUMO

INTRODUCTION: Previous studies have identified that there is limited, although expanding, access to acute hand care in Tennessee. Because of the rapid changes that occurred in health delivery and access during the coronavirus disease pandemic, we reassessed access to acute hand care, with particular interest in the utilization of telemedicine to assess if this increased access. METHOD: We surveyed Tennessee hospitals listed by the Tennessee Hospital Association on their management of hand trauma and availability of telemedicine programs. Census data including population demographics such as race, age, income, and county size were merged with the survey data. Descriptive analysis was performed comparing the 2021 cohort with the historic 2018 cohort and between counties that had hand care versus counties that had no hand care. RESULT: Survey response rate was 71.4% (n = 80 of 112). Telemedicine was used in 80% of the hospitals for other specialties but was not used for hand care. Overall, counties that offered hand trauma care reduced from 60% to 26% from 2018 to 2021 ( P < 0.001). This change was associated with a significant reduction of acute hand care among counties that were classified micropolitan (from 56.3% to 6.7%, P < 0.01). Percentage of hand specialists on staff and 24/7 specialists availability remained low and were similar to the availability in 2018. CONCLUSIONS: There was a decrease of acute hand care access in Tennessee during the coronavirus disease pandemic despite widespread utilization of telemedicine for other specialty consults. Expansion of telemedicine in acute hand care, targeted to micropolitan areas, may help to reduce variability in access to care.


Assuntos
COVID-19 , Traumatismos da Mão , Telemedicina , Humanos , Tennessee/epidemiologia , COVID-19/epidemiologia , Pandemias , Hospitais
15.
Plant Dis ; 108(6): 1612-1620, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38127637

RESUMO

Phytophthora nicotianae causes devastating disease in a range of hosts, including tobacco (N. tabacum L.), tomato, citrus, strawberry, and numerous ornamentals. Black shank, caused by P. nicotianae, is the most economically important disease to tobacco production in Tennessee and North Carolina. Black shank management includes the use of resistant cultivars, crop rotation, and fungicides. Fungicide resistance is a concern for black shank management due to the limited number of active ingredients available and the repeated exposure of pathogen populations to these products. In vitro fungicide sensitivity assays were conducted on 155 P. nicotianae isolates collected in Tennessee and North Carolina in 2021 and 2022 to determine their EC50 values for oxathiapiprolin, mandipropamid, and fluopicolide. The P. nicotianae was isolated predominantly from burley, dark, and flue-cured tobacco showing symptoms of black shank as well as tomato with buckeye rot symptoms. A discriminatory dose was used to determine each isolate's sensitivity to mefenoxam in 2021 and 2022. In 2021, EC50 values were determined for oxathiapiprolin, mandipropamid, and fluopicolide. In 2022, discriminatory doses based on EC75 values were used to determine each isolate's sensitivity to these fungicides. All isolates from the 2 years were sensitive to mefenoxam, mandipropamid, and fluopicolide. One isolate in 2022 was moderately sensitive to oxathiapiprolin, while all other isolates were sensitive.


Assuntos
Fungicidas Industriais , Nicotiana , Phytophthora , Doenças das Plantas , North Carolina , Fungicidas Industriais/farmacologia , Phytophthora/efeitos dos fármacos , Doenças das Plantas/microbiologia , Doenças das Plantas/prevenção & controle , Nicotiana/microbiologia , Tennessee , Piridinas/farmacologia , Amidas/farmacologia , Compostos Heterocíclicos com 3 Anéis/farmacologia , Norbornanos , Alanina/análogos & derivados , Hidrocarbonetos Fluorados , Pirazóis , Ácidos Carboxílicos
16.
Subst Use Misuse ; 59(4): 638-642, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38189325

RESUMO

BACKGROUND: Diphenhydramine (DPH), known as the brand name Benadryl, is an over-the-counter medication associated with accidental ingestion leading to nonfatal overdoses. Additionally, DPH has been used in tandem with illicit substances leading to fatal drug overdoses. OBJECTIVE: In response to DPH being seized with illicit drugs as an adulterant, as well as its growing intentional misuse, we sought to explore its recent involvement in fatal and nonfatal drug overdoses in the state of Tennessee. METHODS: We conducted a statewide cross-sectional study to determine the characteristics of DPH-involved fatal and nonfatal overdoses in Tennessee during 2019-2022 using data from the State Unintentional Drug Overdose Reporting System, the Electronic Surveillance System for the Early Notification of Community-based Epidemics, and the National Forensic Laboratory Information System Public Data Query System. Frequencies were generated to compare demographic characteristics, circumstances, and toxicology between fatal and nonfatal DPH-involved overdoses. RESULTS: We identified 143 suspected nonfatal DPH and 409 fatal DPH-involved overdoses in Tennessee from 2019 to 2022. Nonfatal overdoses remained consistent while fatal overdoses peaked in 2021. Most nonfatal overdoses were under 18 (63.4%), while most fatal overdoses were between 18 and 64 years of age (95.7%). For fatal overdoses, fentanyl was the most prevalent substance on toxicology followed by prescription opioids. CONCLUSION: Nonfatal overdoses remained consistent while fatal overdoses peaked in 2021 in Tennessee. Use of DPH among other illicit substances lends to evidence suggesting its use as an adulterant. Monitoring of DPH-involved fatal and nonfatal overdoses is critical to inform harm reduction initiatives.


Assuntos
Difenidramina , Overdose de Drogas , Humanos , Tennessee/epidemiologia , Estudos Transversais , Overdose de Drogas/epidemiologia , Analgésicos Opioides
17.
J Insect Sci ; 24(2)2024 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-38491949

RESUMO

A survey for parasitoids of Lopholeucaspis japonica Cockerell (Hemiptera: Diaspididae), an exotic scale of woody ornamentals, resulted in the discovery of 3 species of aphelinid parasitoid wasps, Pteroptrix chinensis (Howard), Aphytis hispanicus (Mercet), and Marlattiella prima Howard. This serves as the first report of these parasitoids reared from a host in the state of Tennessee, USA. Despite routine pesticide applications in the surveyed nursery and directed treatments of the infested plants to control the scale outbreak, the percentage of parasitized scale in privet and euonymus shrubs averaged 7.0% and 7.9%, respectively. These parasitoids may be useful in the natural or managed control of this pest in the United States, but additional research is needed to understand how these parasitoids contribute to the control of L. japonica in the landscape and how nursery production practices can be modified to promote parasitoid populations.


Assuntos
Hemípteros , Himenópteros , Praguicidas , Vespas , Animais , Tennessee
18.
Telemed J E Health ; 30(5): 1411-1417, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38150704

RESUMO

Introduction: Teledermatology adoption continues to increase, in part, spurred by the COVID-19 pandemic. This study analyzes the utility and cost savings of a store-and-forward teledermatology consultative system within the Veterans Health Administration (VA). Methods: Retrospective cohort of 4,493 patients across 14 remote sites in Tennessee and Kentucky from May 2017 through August 2019. The study measured the agreement between the teledermatology diagnoses and follow-up face-to-face clinic evaluations as well as the cost effectiveness of the teledermatology program over the study period. Results: Fifty-four percent of patients were recommended for face-to-face appointment for biopsy or further evaluation. Most patients, 80.5% received their face-to-face care by a VA dermatologist. There was a high level of concordance between teledermatologist and clinic dermatologist for pre-malignant and malignant cutaneous conditions. Veterans were seen faster at a VA clinic compared with a community dermatology site. Image quality improved as photographers incorporated teledermatologist feedback. From a cost perspective, teledermatology saved the VA system $1,076,000 in community care costs. Discussion: Teledermatology is a useful diagnostic tool within the VA system providing Veteran care at a cost savings.


Assuntos
COVID-19 , Redução de Custos , Dermatologia , Dermatopatias , Telemedicina , United States Department of Veterans Affairs , Humanos , Dermatologia/economia , Dermatologia/normas , Dermatologia/organização & administração , Estudos Retrospectivos , Dermatopatias/diagnóstico , Dermatopatias/economia , Estados Unidos , Telemedicina/economia , United States Department of Veterans Affairs/organização & administração , Feminino , Kentucky , Masculino , Controle de Qualidade , Pessoa de Meia-Idade , Tennessee , SARS-CoV-2 , Consulta Remota/economia , Idoso , Análise Custo-Benefício
19.
J Stroke Cerebrovasc Dis ; 33(1): 107472, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-37944281

RESUMO

BACKGROUND: While over half of US stroke patients were discharged to home, estimates of geographic access to outpatient stroke rehab facilities are unavailable. The objective of our study was to assess distance and travel time to the nearest outpatient stroke rehab facility in Tennessee, a high stroke prevalence state. METHODS: We systematically scraped Google Maps with the terms "stroke", "rehabilitation", and "outpatient" to identify Tennessee stroke rehab facilities. We then averaged/aggregated Census block-level travel distance and travel time to determine the mean travel distance/time to a facility for each of the 95 Tennessee counties and the overall state. Comparisons of mean travel time/distance were made between rural and urban counties and between low, medium, and high stroke prevalence counties. RESULTS: We found that 79% of facilities were in urban areas. Significantly higher median of mean travel times and distances (p values both <0.001) were observed in rural (22.0 miles, 31.6 min) versus urban counties (10.5 miles, 18.4 min). High (21.5 miles, 32.5 min) and medium (18.7 miles, 28.3 minutes) stroke prevalence counties, which often overlap with rural counties, had significantly higher median of mean travel times and distance than low stroke prevalence counties (7.3 miles, 14.5 min). CONCLUSIONS: Rural Tennessee counties were faced with high stroke prevalence, inadequate facilities, and significantly greater travel distance and time to access care. Additional efforts to address transportation barriers and accelerate telerehabilitation implementation are crucial for improving equal access to stroke aftercare in these areas.


Assuntos
Reabilitação do Acidente Vascular Cerebral , Acidente Vascular Cerebral , Humanos , Tennessee/epidemiologia , Acessibilidade aos Serviços de Saúde , Pacientes Ambulatoriais , Viagem , Acidente Vascular Cerebral/diagnóstico , Acidente Vascular Cerebral/epidemiologia , Acidente Vascular Cerebral/terapia , População Rural
20.
J Women Aging ; 36(2): 152-165, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-37917533

RESUMO

Older women face unique challenges regarding health disparities. This study aims to provide an understanding of older women's perceptions and situated experiences regarding the gendered health disparities they face, which are characterized by the policies related to older women's health and the geopolitical and social norms in which they live. The purpose of this project is to provide policy and decision-makers with insights and a better understanding of older women's experiences and perceptions of the policies that impact their health and healthcare. The data for this study was collected through semi-structured interviews with twelve women in Appalachian East Tennessee. Areas examined include: the women's perceived impact of federal, state, and local policies on the participants, particularly of Medicare and Medicaid; the role of social norming and health narratives, particularly stigmatization, discrimination, and health marginalization of older women; and the role of place and place-based drivers on these areas. This study sought to determine if these factors impact the participants' awareness or lack of awareness of policies related to older women. Findings showed that older women in East Tennessee lacked knowledge of health policies, that older women perceive systemic and individual discrimination in policymaking, clinical care, and health research, and that they perceive that place-based drivers have impacted their access to healthcare. These findings have implications for policymaking and intervention design in co-production with older women in order to mitigate older women's health disparities.


Assuntos
Medicaid , Medicare , Idoso , Feminino , Humanos , Estados Unidos , Tennessee , Saúde da Mulher , Política de Saúde , Pesquisa Qualitativa
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