Detalhe da pesquisa
1.
TNF dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species.
Cell
; 153(3): 521-34, 2013 Apr 25.
Artigo
Inglês
| MEDLINE | ID: mdl-23582643
2.
Tryptophan biosynthesis protects mycobacteria from CD4 T-cell-mediated killing.
Cell
; 155(6): 1296-308, 2013 Dec 05.
Artigo
Inglês
| MEDLINE | ID: mdl-24315099
3.
A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection.
PLoS Biol
; 22(4): e3002259, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38683873
4.
Converting cancer therapies into cures: lessons from infectious diseases.
Cell
; 148(6): 1089-98, 2012 Mar 16.
Artigo
Inglês
| MEDLINE | ID: mdl-22424221
5.
Outwitting evolution: fighting drug-resistant TB, malaria, and HIV.
Cell
; 148(6): 1271-83, 2012 Mar 16.
Artigo
Inglês
| MEDLINE | ID: mdl-22424234
6.
Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline.
Nature
; 589(7840): 143-147, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33299175
7.
An NAD+ Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death.
Mol Cell
; 73(6): 1282-1291.e8, 2019 03 21.
Artigo
Inglês
| MEDLINE | ID: mdl-30792174
8.
Rapid, antibiotic incubation-free determination of tuberculosis drug resistance using machine learning and Raman spectroscopy.
Proc Natl Acad Sci U S A
; 121(25): e2315670121, 2024 Jun 18.
Artigo
Inglês
| MEDLINE | ID: mdl-38861604
9.
Rifampicin drug resistance and host immunity in tuberculosis: more than meets the eye.
Trends Immunol
; 44(9): 712-723, 2023 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37543504
10.
Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism.
Cell
; 145(1): 39-53, 2011 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21376383
11.
Mycobacterial Mutagenesis and Drug Resistance Are Controlled by Phosphorylation- and Cardiolipin-Mediated Inhibition of the RecA Coprotease.
Mol Cell
; 72(1): 152-161.e7, 2018 10 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30174294
12.
The human proton pump inhibitors inhibit Mycobacterium tuberculosis rifampicin efflux and macrophage-induced rifampicin tolerance.
Proc Natl Acad Sci U S A
; 120(7): e2215512120, 2023 02 14.
Artigo
Inglês
| MEDLINE | ID: mdl-36763530
13.
Effectiveness of a comprehensive package based on electronic medication monitors at improving treatment outcomes among tuberculosis patients in Tibet: a multicentre randomised controlled trial.
Lancet
; 403(10430): 913-923, 2024 Mar 09.
Artigo
Inglês
| MEDLINE | ID: mdl-38309280
14.
Shorter Treatment for Nonsevere Tuberculosis in African and Indian Children.
N Engl J Med
; 386(10): 911-922, 2022 03 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35263517
15.
Bedaquiline-Pretomanid-Linezolid Regimens for Drug-Resistant Tuberculosis.
N Engl J Med
; 387(9): 810-823, 2022 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36053506
16.
A novel class of antimicrobial drugs selectively targets a Mycobacterium tuberculosis PE-PGRS protein.
PLoS Biol
; 20(5): e3001648, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35639773
17.
Mathematical model of oxygen, nutrient, and drug transport in tuberculosis granulomas.
PLoS Comput Biol
; 20(2): e1011847, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38335224
18.
Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.
Nature
; 571(7763): 72-78, 2019 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31217586
19.
A Nanopore Sequencing-based Pharmacogenomic Panel to Personalize Tuberculosis Drug Dosing.
Am J Respir Crit Care Med
; 209(12): 1486-1496, 2024 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38647526
20.
Infectious and clinical tuberculosis trajectories: Bayesian modeling with case finding implications.
Proc Natl Acad Sci U S A
; 119(52): e2211045119, 2022 12 27.
Artigo
Inglês
| MEDLINE | ID: mdl-36534797