Pesquisa | Secretaria de Estado da Saúde

1.

A single-embryo, single-cell time-resolved model for mouse gastrulation.

Mittnenzweig, Markus; Mayshar, Yoav; Cheng, Saifeng; Ben-Yair, Raz; Hadas, Ron; Rais, Yoach; Chomsky, Elad; Reines, Netta; Uzonyi, Anna; Lumerman, Lior; Lifshitz, Aviezer; Mukamel, Zohar; Orenbuch, Ayelet-Hashahar; Tanay, Amos; Stelzer, Yonatan.

Cell; 184(11): 2825-2842.e22, 2021 05 27.

Artigo Inglês | MEDLINE | ID: mdl-33932341

2.

Compromised SARS-CoV-2-specific placental antibody transfer.

Atyeo, Caroline; Pullen, Krista M; Bordt, Evan A; Fischinger, Stephanie; Burke, John; Michell, Ashlin; Slein, Matthew D; Loos, Carolin; Shook, Lydia L; Boatin, Adeline A; Yockey, Laura J; Pepin, David; Meinsohn, Marie-Charlotte; Nguyen, Ngoc Minh Phuong; Chauvin, Maeva; Roberts, Drucilla; Goldfarb, Ilona T; Matute, Juan D; James, Kaitlyn E; Yonker, Lael M; Bebell, Lisa M; Kaimal, Anjali J; Gray, Kathryn J; Lauffenburger, Douglas; Edlow, Andrea G; Alter, Galit.

Cell; 184(3): 628-642.e10, 2021 02 04.

Artigo Inglês | MEDLINE | ID: mdl-33476549

3.

Microbial exposure during early human development primes fetal immune cells.

Mishra, Archita; Lai, Ghee Chuan; Yao, Leong Jing; Aung, Thet Tun; Shental, Noam; Rotter-Maskowitz, Aviva; Shepherdson, Edwin; Singh, Gurmit Singh Naranjan; Pai, Rhea; Shanti, Adhika; Wong, Regina Men Men; Lee, Andrea; Khyriem, Costerwell; Dutertre, Charles Antoine; Chakarov, Svetoslav; Srinivasan, K G; Shadan, Nurhidaya Binte; Zhang, Xiao-Meng; Khalilnezhad, Shabnam; Cottier, Fabien; Tan, Alrina Shin Min; Low, Gillian; Chen, Phyllis; Fan, Yiping; Hor, Pei Xiang; Lee, Avery Khoo May; Choolani, Mahesh; Vermijlen, David; Sharma, Ankur; Fuks, Garold; Straussman, Ravid; Pavelka, Norman; Malleret, Benoit; McGovern, Naomi; Albani, Salvatore; Chan, Jerry Kok Yen; Ginhoux, Florent.

Cell; 184(13): 3394-3409.e20, 2021 06 24.

Artigo Inglês | MEDLINE | ID: mdl-34077752

4.

Stressful Beginnings with Long-Term Consequences.

Consiglio, Camila Rosat; Brodin, Petter.

Cell; 180(5): 820-821, 2020 03 05.

Artigo Inglês | MEDLINE | ID: mdl-32142672

5.

Stealth Killing by Uterine NK Cells for Tolerance and Tissue Homeostasis.

Dogra, Pranay; Farber, Donna L.

Cell; 182(5): 1074-1076, 2020 09 03.

Artigo Inglês | MEDLINE | ID: mdl-32888492

6.

Metabolic Dynamics and Prediction of Gestational Age and Time to Delivery in Pregnant Women.

Liang, Liang; Rasmussen, Marie-Louise Hee; Piening, Brian; Shen, Xiaotao; Chen, Songjie; Röst, Hannes; Snyder, John K; Tibshirani, Robert; Skotte, Line; Lee, Norman Cy; Contrepois, Kévin; Feenstra, Bjarke; Zackriah, Hanyah; Snyder, Michael; Melbye, Mads.

Cell; 181(7): 1680-1692.e15, 2020 06 25.

Artigo Inglês | MEDLINE | ID: mdl-32589958

7.

Maternal Fecal Microbiota Transplantation in Cesarean-Born Infants Rapidly Restores Normal Gut Microbial Development: A Proof-of-Concept Study.

Korpela, Katri; Helve, Otto; Kolho, Kaija-Leena; Saisto, Terhi; Skogberg, Kirsi; Dikareva, Evgenia; Stefanovic, Vedran; Salonen, Anne; Andersson, Sture; de Vos, Willem M.

Cell; 183(2): 324-334.e5, 2020 10 15.

Artigo Inglês | MEDLINE | ID: mdl-33007265

8.

Decidual NK Cells Transfer Granulysin to Selectively Kill Bacteria in Trophoblasts.

Crespo, Ângela C; Mulik, Sachin; Dotiwala, Farokh; Ansara, James A; Sen Santara, Sumit; Ingersoll, Kayleigh; Ovies, Cristian; Junqueira, Caroline; Tilburgs, Tamara; Strominger, Jack L; Lieberman, Judy.

Cell; 182(5): 1125-1139.e18, 2020 09 03.

Artigo Inglês | MEDLINE | ID: mdl-32822574

9.

Long-Term Programming of CD8 T Cell Immunity by Perinatal Exposure to Glucocorticoids.

Hong, Jun Young; Lim, Jaechul; Carvalho, Fernando; Cho, Jen Young; Vaidyanathan, Bharat; Yu, Shuang; Annicelli, Charles; Ip, W K Eddie; Medzhitov, Ruslan.

Cell; 180(5): 847-861.e15, 2020 03 05.

Artigo Inglês | MEDLINE | ID: mdl-32142678

10.

The Role of Immune Factors in Shaping Fetal Neurodevelopment.

Lu-Culligan, Alice; Iwasaki, Akiko.

Annu Rev Cell Dev Biol; 36: 441-468, 2020 10 06.

Artigo Inglês | MEDLINE | ID: mdl-32722920

11.

The legacy of maternal SARS-CoV-2 infection on the immunology of the neonate.

Gee, Sarah; Chandiramani, Manju; Seow, Jeffrey; Pollock, Emily; Modestini, Carlotta; Das, Abhishek; Tree, Timothy; Doores, Katie J; Tribe, Rachel M; Gibbons, Deena L.

Nat Immunol; 22(12): 1490-1502, 2021 12.

Artigo Inglês | MEDLINE | ID: mdl-34616036

12.

Maternal gut bacteria drive intestinal inflammation in offspring with neurodevelopmental disorders by altering the chromatin landscape of CD4⁺ T cells.

Kim, Eunha; Paik, Donggi; Ramirez, Ricardo N; Biggs, Delaney G; Park, Youngjun; Kwon, Ho-Keun; Choi, Gloria B; Huh, Jun R.

Immunity; 55(1): 145-158.e7, 2022 01 11.

Artigo Inglês | MEDLINE | ID: mdl-34879222

13.

Over-celling fetal microbial exposure.

Kennedy, Katherine M; Bellissimo, Christian J; Breznik, Jessica A; Barrett, Jon; Braun, Thorsten; Bushman, Frederic D; De Goffau, Marcus; Elovitz, Michal A; Heimesaat, Markus M; Konnikova, Liza; Koren, Omry; Parry, Samuel; Rossi, Laura; Segata, Nicola; Simmons, Rebecca A; Surette, Michael G; Walter, Jens; Sloboda, Deborah M.

Cell; 184(24): 5839-5841, 2021 11 24.

Artigo Inglês | MEDLINE | ID: mdl-34822779

14.

Uterine NK cell education: Learning the ropes in pregnancy.

Wells, Alexandra I; Coyne, Carolyn B.

Immunity; 54(6): 1102-1104, 2021 06 08.

Artigo Inglês | MEDLINE | ID: mdl-34107267

15.

IL-6 boosts synaptogenesis STAT!

Faust, Travis E; Schafer, Dorothy P.

Immunity; 54(11): 2444-2446, 2021 11 09.

Artigo Inglês | MEDLINE | ID: mdl-34758335

16.

The CD94/NKG2A inhibitory receptor educates uterine NK cells to optimize pregnancy outcomes in humans and mice.

Shreeve, Norman; Depierreux, Delphine; Hawkes, Delia; Traherne, James A; Sovio, Ulla; Huhn, Oisin; Jayaraman, Jyothi; Horowitz, Amir; Ghadially, Hormas; Perry, John R B; Moffett, Ashley; Sled, John G; Sharkey, Andrew M; Colucci, Francesco.

Immunity; 54(6): 1231-1244.e4, 2021 06 08.

Artigo Inglês | MEDLINE | ID: mdl-33887202

17.

Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring.

Mirabella, Filippo; Desiato, Genni; Mancinelli, Sara; Fossati, Giuliana; Rasile, Marco; Morini, Raffaella; Markicevic, Marija; Grimm, Christina; Amegandjin, Clara; Termanini, Alberto; Peano, Clelia; Kunderfranco, Paolo; di Cristo, Graziella; Zerbi, Valerio; Menna, Elisabetta; Lodato, Simona; Matteoli, Michela; Pozzi, Davide.

Immunity; 54(11): 2611-2631.e8, 2021 11 09.

Artigo Inglês | MEDLINE | ID: mdl-34758338

18.

Viral infection of the ovaries compromises pregnancy and reveals innate immune mechanisms protecting fertility.

Tomac, Jelena; Mazor, Marija; Lisnic, Berislav; Golemac, Mijo; Kvestak, Daria; Bralic, Marina; Bilic Zulle, Lidija; Brinkmann, Melanie M; Dölken, Lars; Reinert, Line S; Paludan, Soren R; Krmpotic, Astrid; Jonjic, Stipan; Juranic Lisnic, Vanda.

Immunity; 54(7): 1478-1493.e6, 2021 07 13.

Artigo Inglês | MEDLINE | ID: mdl-34015257

19.

Megakaryocyte production is sustained by direct differentiation from erythromyeloid progenitors in the yolk sac until midgestation.

Iturri, Lorea; Freyer, Laina; Biton, Anne; Dardenne, Pascal; Lallemand, Yvan; Gomez Perdiguero, Elisa.

Immunity; 54(7): 1433-1446.e5, 2021 07 13.

Artigo Inglês | MEDLINE | ID: mdl-34062116

20.

Highly rigid H3.1/H3.2-H3K9me3 domains set a barrier for cell fate reprogramming in trophoblast stem cells.

Hada, Masashi; Miura, Hisashi; Tanigawa, Akie; Matoba, Shogo; Inoue, Kimiko; Ogonuki, Narumi; Hirose, Michiko; Watanabe, Naomi; Nakato, Ryuichiro; Fujiki, Katsunori; Hasegawa, Ayumi; Sakashita, Akihiko; Okae, Hiroaki; Miura, Kento; Shikata, Daiki; Arima, Takahiro; Shirahige, Katsuhiko; Hiratani, Ichiro; Ogura, Atsuo.

Genes Dev; 36(1-2): 84-102, 2022 01 01.

Artigo Inglês | MEDLINE | ID: mdl-34992147

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