Avaliação laboratorial da toxicidade molecular em eritrócitos talassêmicos / Laboratorial evaluation of molecular toxicity in thalassemic erythrocytes
Rev. bras. hematol. hemoter
; 28(4): 301-302, out.-dez. 2006. ilus, tab
Article
en Pt
| LILACS
| ID: lil-456243
Biblioteca responsable:
BR408.1
ABSTRACT
Oxygen-derived free radical damage is associated with the molecular toxicity of hemoglobin. Especially in thalassemia syndromes, this toxicity has a relationship with "free" alpha globin concentrations. This study of beta thalassemia trait blood samples from 39 individuals shows that the evaluation of methemoglobin is a sensitive method of indicating molecular toxicity and the superoxide dismutase concentration revealing the intensity of oxidative stress of this process.
Texto completo:
1
Banco de datos:
LILACS
Asunto principal:
Talasemia
/
Talasemia beta
/
Técnicas de Laboratorio Clínico
/
Eritrocitos
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
Pt
Año:
2006
Tipo del documento:
Article