Cloning and sequencing of mouse glutaredoxin (grx) cDNA.
DNA Seq
; 10(3): 179-82, 1999.
Article
en En
| MEDLINE
| ID: mdl-10647820
ABSTRACT
Glutaredoxins are small proteins (12 kDa) with a conserved active sequence Cys-Pro-Tyr(-Phe)-Cys that catalyse GSH-disulfide oxidoreduction reactions in the presence of NADPH and glutathione reductase. Many mammalian glutaredoxins have been characterized and human and pig cDNA sequence determined. However, no mouse glutaredoxin cDNA or protein sequence has yet been reported. We have cloned a cDNA from a mouse liver library that encodes the putative mouse glutaredoxin homologue. The deduced polypeptide sequence encodes a 107 amino acid protein displaying a high degree of homology with other members of the glutaredoxin family.
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Banco de datos:
MEDLINE
Asunto principal:
Oxidorreductasas
/
Proteínas
Límite:
Animals
/
Humans
Idioma:
En
Año:
1999
Tipo del documento:
Article