Ventricular fibrillation: how do we stop the waves from breaking?

Weiss, J N; Chen, P S; Qu, Z; Karagueuzian, H S; Garfinkel, A

Weiss, J N; Chen, P S; Qu, Z; Karagueuzian, H S; Garfinkel, A.

Weiss JN; Cardiovascular Research Laboratory and the Departments of Medicine (Cardiology), Physiology and Physiological Science, UCLA School of Medicine and Cedars-Sinai Medical Center, Los Angeles, CA 90095-1760, USA. jweiss@mednet.ucla.edu

Circ Res ; 87(12): 1103-7, 2000 Dec 08.

Article en En | MEDLINE | ID: mdl-11110766

ABSTRACT

ABSTRACT

Combined experimental and theoretical developments have demonstrated that in addition to preexisting electrophysiological heterogeneities, cardiac electrical restitution properties contribute to breakup of reentrant wavefronts during cardiac fibrillation. Developing therapies that favorably alter electrical restitution properties have promise as a new paradigm for preventing fibrillation.

Asunto(s)

Fibrilación Ventricular/fisiopatología; Potenciales de Acción/efectos de los fármacos; Antiarrítmicos/uso terapéutico; Arritmias Cardíacas/tratamiento farmacológico; Arritmias Cardíacas/etiología; Electrofisiología; Historia Moderna 1601-; Humanos; Fibrilación Ventricular/prevención & control

Search on Google

Imprimir

XML

PubMed Links

Banco de datos: MEDLINE Asunto principal: Fibrilación Ventricular Tipo de estudio: Etiology_studies Límite: Humans Idioma: En Año: 2000 Tipo del documento: Article

Search on Google

Imprimir

XML

PubMed Links

Banco de datos: MEDLINE Asunto principal: Fibrilación Ventricular Tipo de estudio: Etiology_studies Límite: Humans Idioma: En Año: 2000 Tipo del documento: Article